About
Passionate about the intersection of computer science and biology.
Activity
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A couple of weeks ago, I transitioned out of Tierra, the company I founded 9 years ago. I do so with mixed and bittersweet emotions, having watched…
A couple of weeks ago, I transitioned out of Tierra, the company I founded 9 years ago. I do so with mixed and bittersweet emotions, having watched…
Liked by Nicholas Larus-Stone
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This was fun to build over the weekend! Can you tell the difference between an AI and a human?
This was fun to build over the weekend! Can you tell the difference between an AI and a human?
Shared by Nicholas Larus-Stone
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❓Who's the AI? A fun little game: you get placed in a chatroom with two other players. Any number of them may be an AI You have 60s to chat with…
❓Who's the AI? A fun little game: you get placed in a chatroom with two other players. Any number of them may be an AI You have 60s to chat with…
Liked by Nicholas Larus-Stone
Experience
Education
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Harvard University
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Activities and Societies: Captain of Harvard Club Squash, Director of External Relations for Harvard Computer Society, Director of Web Development for Freshman Intramurals, Harvard University PRISE Fellow, Peer Advising Fellow, Teaching Fellow, Phillips Brooks House Association Volunteer
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Activities and Societies: Queens' College University Challenge, Lacrosse
Licenses & Certifications
Volunteer Experience
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Volunteer
Harvard Youth Leadership Initiative
- 1 year 10 months
Publications
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Systems Optimizations for Learning Certifiably Optimal Rule Lists
SysML
Other authors -
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Learning Certifiably Optimal Rule Lists
KDD 2017
We present the design and implementation of a custom discrete optimization technique for building rule lists over a categorical feature space. Our algorithm provides the optimal solution, with a certificate of optimality. By leveraging algorithmic bounds, ecient data structures, and computational reuse, we achieve several orders of magnitude speedup in time and a massive reduction of memory consumption. We demonstrate that our approach produces optimal rule lists on practical problems in…
We present the design and implementation of a custom discrete optimization technique for building rule lists over a categorical feature space. Our algorithm provides the optimal solution, with a certificate of optimality. By leveraging algorithmic bounds, ecient data structures, and computational reuse, we achieve several orders of magnitude speedup in time and a massive reduction of memory consumption. We demonstrate that our approach produces optimal rule lists on practical problems in seconds. This framework is a novel alternative to CART and other decision tree methods.
Other authorsSee publication
Courses
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Artificial Intelligence
CS 182
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Computational Transcriptomics
SCRB152
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Computer Security
R209
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Computing Hardware
CS 141
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Data Structures and Algorithms
CS 124
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Discrete Mathematics for Computer Science
CS 20
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Introduction to Computer Science I
CS 50
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Introduction to Computer Science II
CS 51
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Introduction to Probability
Stat 110
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Machine Learning
CS 181
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Modern Compiler Design
L25
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Multicore Semantics and Programming
R204
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Operating Systems
CS 161
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Probabilistic Machine Learning
LE49
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Supervised Reading and Research
CS91r
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Systems Programming and Machine Organization
CS 61
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Theory of Computation
CS 121
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Topics in Cryptography and Privacy
CS227r
Honors & Awards
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Phi Beta Kappa
Harvard University
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KPCB Fellow
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Languages
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Spanish
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More activity by Nicholas
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Excited to share that Quotient Therapeutics has entered into a strategic partnership with Pfizer to identify potential novel targets for the…
Excited to share that Quotient Therapeutics has entered into a strategic partnership with Pfizer to identify potential novel targets for the…
Liked by Nicholas Larus-Stone
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Enjoyed speaking with Andrew Dunn to announce NOETIK $40M Series A led by Polaris Partners, Amy Schulman. The NOETIK team has made incredible…
Enjoyed speaking with Andrew Dunn to announce NOETIK $40M Series A led by Polaris Partners, Amy Schulman. The NOETIK team has made incredible…
Liked by Nicholas Larus-Stone
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Indeed: finding and optimizing drugs in rudimentary in vitro assays is like “finding the best sprinter and sending them to run a marathon” Thank you…
Indeed: finding and optimizing drugs in rudimentary in vitro assays is like “finding the best sprinter and sending them to run a marathon” Thank you…
Liked by Nicholas Larus-Stone
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This hackathon is a fantastic opportunity for anyone interested in the intersection of biology and AI! Join us to gain firsthand experience with one…
This hackathon is a fantastic opportunity for anyone interested in the intersection of biology and AI! Join us to gain firsthand experience with one…
Liked by Nicholas Larus-Stone
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Not only an amazing event, also a very nice opportunity to visit the Bio Base Europe Pilot Plant and see it's new 75 000 L fermenter in action!
Not only an amazing event, also a very nice opportunity to visit the Bio Base Europe Pilot Plant and see it's new 75 000 L fermenter in action!
Liked by Nicholas Larus-Stone
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A few days ago, we paid a visit to Eigen Therapeutics at their HQ in Redwood City. As one would expect from a biotech company, they did not lead us…
A few days ago, we paid a visit to Eigen Therapeutics at their HQ in Redwood City. As one would expect from a biotech company, they did not lead us…
Liked by Nicholas Larus-Stone
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A flavor of what I've been working on at Sphinx...
A flavor of what I've been working on at Sphinx...
Liked by Nicholas Larus-Stone
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I am beyond excited to announce that I have been promoted to Chief Scientific Officer at ImmuneBridge! This is something that, until recently, I had…
I am beyond excited to announce that I have been promoted to Chief Scientific Officer at ImmuneBridge! This is something that, until recently, I had…
Liked by Nicholas Larus-Stone
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Q: How many ways can data inside a CSV or spreadsheet be structured? A: A lot! At Sphinx Bio, we've been tackling this challenge head-on. We're…
Q: How many ways can data inside a CSV or spreadsheet be structured? A: A lot! At Sphinx Bio, we've been tackling this challenge head-on. We're…
Shared by Nicholas Larus-Stone
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Nice writeup in Nature Biotech about our work with Wisconsin Alumni Research Foundation (WARF) to demonstrate Ginkgo Bioworks, Inc.'s technology for…
Nice writeup in Nature Biotech about our work with Wisconsin Alumni Research Foundation (WARF) to demonstrate Ginkgo Bioworks, Inc.'s technology for…
Liked by Nicholas Larus-Stone
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I'll be heading to InsureTech Connect with my co-founder Michael and I'm looking forward to speaking on a panel about the future of agent-led…
I'll be heading to InsureTech Connect with my co-founder Michael and I'm looking forward to speaking on a panel about the future of agent-led…
Liked by Nicholas Larus-Stone
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I'm excited to launch the free tier of PlatePlanner! PlatePlanner is a tool for research scientists that helps them quickly create beautiful…
I'm excited to launch the free tier of PlatePlanner! PlatePlanner is a tool for research scientists that helps them quickly create beautiful…
Liked by Nicholas Larus-Stone
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In the fourth and final part of our series on Octant’s multiplexing capabilities, we cover the power of Deep Mutational Scans (DMS) to map function…
In the fourth and final part of our series on Octant’s multiplexing capabilities, we cover the power of Deep Mutational Scans (DMS) to map function…
Liked by Nicholas Larus-Stone
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“The gap between a small required effort and zero effort is vast, from the user's perspective.”
“The gap between a small required effort and zero effort is vast, from the user's perspective.”
Posted by Nicholas Larus-Stone
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Check out my latest on developing an open-source framework for scientific automation. I propose a framework to integrate robots and controllers…
Check out my latest on developing an open-source framework for scientific automation. I propose a framework to integrate robots and controllers…
Liked by Nicholas Larus-Stone
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