About
Steering the commercial strategy for Bruker in the Central US, my role as Regional Sales…
Activity
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Rotation grad students should attend lab meetings. Its important to be in the lab as much as possible, but you'll also learn a lot about group…
Rotation grad students should attend lab meetings. Its important to be in the lab as much as possible, but you'll also learn a lot about group…
Liked by Savannah Snyder
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Calling all NMR experts (especially those with NP structure elucidation experience)! If you have ever been interested in pivoting to industry, this…
Calling all NMR experts (especially those with NP structure elucidation experience)! If you have ever been interested in pivoting to industry, this…
Liked by Savannah Snyder
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I am excited to share our tutorial article on nano-DESI imaging in ACS Measurement Science Au. We describe the basics of the technique and provide…
I am excited to share our tutorial article on nano-DESI imaging in ACS Measurement Science Au. We describe the basics of the technique and provide…
Liked by Savannah Snyder
Experience
Education
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The University of Akron
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Conducting analytical research of polymers using various mass spectrometers (i.e. MALDI-ToF, ESI-MS, etc.)
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Activities and Societies: Kanga Blue A Capella Honors Club Intramural Sports
•Participated in an all-girls A Capella group "Kanga Blue". President of the Honors Club. 2 years study of Spanish.
•Exxon Corporation Chemistry Scholarship, 2014. Julias Muelstein Scholarship in Chemistry, 2013. Presented at CERM 2014 Pittsburgh, PA, 2014.
•Graduated with Honors in Chemistry.
Volunteer Experience
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Judge: Akron Public Schools Science Fair
Akron Public Schools
- 2 years 1 month
Judging of middle school to high school level science projects in the Akron area.
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Sustainability Taskforce Member
Downtown Cuyahoga Falls Partnership
- Present 5 years
Environment
Working toward greater environmental sustainability of the Downtown Cuyahoga Falls area.
-Chose, organized, and helped lead the planting of native pollinators in 8 large planters downtown, with educational plaques describing the plants themselves and the pollinators that need them
-Worked with undergraduate University of Akron students on a project to compile data on green spaces and their impact on community, to bring to the city in order to create more green spaces -
Tree Board Member
City of Cuyahoga Falls Tree Board
- Present 1 year 8 months
Environment
As a member of the tree board, it is my duty to study, investigate, advise, develop and/or update annually, a written plan for the care, preservation, pruning, planting, replanting, removal or disposition of trees and shrubs along streets and in other public areas not under the control of the Park and Recreation Board.
Publications
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Elucidation of Low Molecular Weight Polymers in Vehicular Engine Deposits by Multidimensional Mass Spectrometry
ACS: Energy & Fuels
Engine oil is mainly comprised of base oils and various additives, which are low molecular weight polymers mixed into the oil resulting in a polymer blend. Dispersants and detergents, the two most abundant additives, are intended to keep the engine free of particulate but are not always successful. At high temperatures, species not combusted may undergo oxidation and degradation or create other byproducts, generating particulate deposition. Knowledge of the molecular makeup of these byproducts…
Engine oil is mainly comprised of base oils and various additives, which are low molecular weight polymers mixed into the oil resulting in a polymer blend. Dispersants and detergents, the two most abundant additives, are intended to keep the engine free of particulate but are not always successful. At high temperatures, species not combusted may undergo oxidation and degradation or create other byproducts, generating particulate deposition. Knowledge of the molecular makeup of these byproducts is essential, as particulate accumulation can cause serious issues to the engine and ultimately to the operator. In this study, unknown deposits from the air-intake valve of a vehicular engine have been analyzed via a palette of mass spectrometry (MS) methods, including matrix-assisted laser desorption/ionization MS with postacquisition data processing, atmospheric solids analysis probe MS, and electrospray ionization MS interfaced with 2D separation via reversed-phase liquid chromatography and ion mobility spectrometry. Low molecular weight, aminated poly(propylene glycol) and polyisobutylene detergents and a poly(methyl methacrylate) viscosity modifier were conclusively identified in the deposit, along with oxidized polyethylene chains leaked into the oil/additives blend from vehicular tubing and tanks. The use of different methods was essential for the confident elucidation of the low molecular weight macromolecules giving rise to the vehicular engine particulates.
Other authorsSee publication -
Amino Acid Specific Nonenzymatic Montmorillonite-Promoted RNA Polymerization
ChemSystemsChem
Understanding prebiotic RNA synthesis is essential to both the RNA world and RNA‐protein co‐evolution theories of the origin of life. Nonenzymatic templated RNA synthesis occurs in solution or by montmorillonite clay heterogenous catalysis but the high magnesium concentrations required are deleterious to protocell membranes. Here, we explore a multicomponent environmental system consisting of amino acids, RNA mononucleotides and montmorillonite at various Mg2+ concentrations. We show that…
Understanding prebiotic RNA synthesis is essential to both the RNA world and RNA‐protein co‐evolution theories of the origin of life. Nonenzymatic templated RNA synthesis occurs in solution or by montmorillonite clay heterogenous catalysis but the high magnesium concentrations required are deleterious to protocell membranes. Here, we explore a multicomponent environmental system consisting of amino acids, RNA mononucleotides and montmorillonite at various Mg2+ concentrations. We show that specific alpha amino acids, especially those that were prebiotically most relevant, act as prebiotic coenzymes and further enhance montmorillonite‐catalyzed polymerization in a cooperative mechanism to produce even longer RNA oligomers. Significantly, and different from template‐directed nonenzymatic RNA polymerization by primer extension, added Mg2+ is not required for montmorillonite‐catalyzed polymerization, especially as enhanced by specific amino acids. Thus amino acid specific montmorillonite‐catalyzed RNA polymerization is compatible with protocell membranes and could occur in a wider variety of geochemical environments of various Mg2+ concentrations.
Other authorsSee publication -
Sequencing of Side-Chain Liquid Crystalline Copolymers by Matrix-Assisted Laser Desorption/Ionization Tandem Mass Spectrometry
Polymers
Polyether based side-chain liquid crystalline (SCLC) copolymers with distinct microstructures were prepared using living anionic polymerization techniques. The composition, end groups, purity, and sequence of the resulting copolymers were elucidated by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) and tandem mass spectrometry (MS/MS). MALDI-MS analysis confirmed the presence of (CH3)3CO– and –H end groups at the initiating (α) and terminating (ω) chain end…
Polyether based side-chain liquid crystalline (SCLC) copolymers with distinct microstructures were prepared using living anionic polymerization techniques. The composition, end groups, purity, and sequence of the resulting copolymers were elucidated by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) and tandem mass spectrometry (MS/MS). MALDI-MS analysis confirmed the presence of (CH3)3CO– and –H end groups at the initiating (α) and terminating (ω) chain end, respectively, and allowed determination of the molecular weight distribution and comonomer content of the copolymers. The comonomer positions along the polymer chain were identified by MS/MS, from the fragments formed via C–O and C–C bond cleavages in the polyether backbone. Random and block architectures could readily be distinguished by the contiguous fragment series formed in these reactions. Notably, backbone C–C bond scission was promoted by a radical formed via initial C–O bond cleavage in the mesogenic side chain. This result documents the ability of a properly substituted side chain to induce sequence indicative bond cleavages in the polyether backbone.
Other authorsSee publication -
Synthesis and 3D Printing of PEG-Poly(propylene fumarate) Diblock and Triblock Copolymer Hydrogels
ACS Macro Letters
PEG-based hydrogels are used widely in
exploratory tissue engineering applications but in general
lack chemical and structural diversity. Additive manufacturing
offers pathways to otherwise unattainable scaffold morphol-
ogies but has been applied sparingly to cross-linked hydrogels.
Herein, monomethyl ether poly(ethylene glycol) (PEG) and
PEG−diol were used to initiate the ring-opening copoly-
merization (ROCOP) of maleic anhydride and propylene oxide to yield well-defined…PEG-based hydrogels are used widely in
exploratory tissue engineering applications but in general
lack chemical and structural diversity. Additive manufacturing
offers pathways to otherwise unattainable scaffold morphol-
ogies but has been applied sparingly to cross-linked hydrogels.
Herein, monomethyl ether poly(ethylene glycol) (PEG) and
PEG−diol were used to initiate the ring-opening copoly-
merization (ROCOP) of maleic anhydride and propylene oxide to yield well-defined diblock and triblock copolymers of PEG− poly(propylene maleate) (PPM) and ultimately PEG-poly(propylene fumarate) (PPF) with different molecular mass PEG macroinitiators and block length ratios. Using continuous digital light processing (cDLP), hydrogels were photochemically printed from an aqueous solution which resulted in a 10-fold increase in elongation at break compared to traditional diethyl fumarate (DEF) based printing. Furthermore, PPF−PEG−PPF triblock hydrogels were also found to be biocompatible in vitro across a number of engineered MC3T3, NIH3T3, and primary Schwann cells.Other authorsSee publication -
Chlorine/oxygen transfer reactions of [PCl2N]3 using oxygenated Lewis bases as a possible route to [PON]3
Phosphorus, Sulfur, and Silicon
Abstract: "The reactions of [PCl2N]3 with oxygen containing Lewis bases (O=E) such as hexamethylphosphoramide (HMPA) and triethylphosphine oxide result in Cl/O exchange. The reactions occur via a two-step process which involves (1) formation of an intermediate salt [P3N3Cl5O]- P3N3Cl4O-O=E and [E-Cl]+[Cl]−. In addition to spectral characterizations, both phosphazene products of the HMPA reactions have been characterized by X-ray crystallography. As shown by reaction chemistry and the…
Abstract: "The reactions of [PCl2N]3 with oxygen containing Lewis bases (O=E) such as hexamethylphosphoramide (HMPA) and triethylphosphine oxide result in Cl/O exchange. The reactions occur via a two-step process which involves (1) formation of an intermediate salt [P3N3Cl5O]- P3N3Cl4O-O=E and [E-Cl]+[Cl]−. In addition to spectral characterizations, both phosphazene products of the HMPA reactions have been characterized by X-ray crystallography. As shown by reaction chemistry and the Gutmann–Beckett Lewis acidity scale, the P=O of the phosphazene ring in P3N3Cl4O-O=E has a strong Lewis acid character. We also discuss attempts to use other O=E and more vigorous reaction conditions with the goal of preparing [PON]3 or its base-stabilized adducts. Such molecules could be precursors to novel PNO materials."
Other authorsSee publication -
Oxygen/Chlorine Transfer Reactions of Cyclic Chlorophosphazenes Using Methane Sulfonic Acid
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Substitution of oxygen atoms onto a trichlorophosphazene molecule was attempted, succeeding in partial substitution.
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Courses
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Advanced Chemistry Lab I
3150:380
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Advanced Chemistry Lab II
3150:381
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Advanced Chemistry Lab Ill
3150:480
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Advanced Inorganic Chemistry
3150:472
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Analytical Chemistry I
3150:423
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Analytical Chemistry II
3150:424
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Biochemistry I
3150:401
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Biochemistry: Structural Biology of Proteins and Nucleic Acids
3150:715
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Calculus II
3450:222
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Calculus III
3450:223
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Chemical Education
3150:592
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Elementary Classical Physics I
3650:291
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Elementary Classical Physics II
3650:292
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Honors Colloquium: Natural Science
1870:470
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Honors Colloquium: Social Science
1870:360
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Honors Project in Chemistry
3150:497
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Introduction to Differential Equations
3450:335
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Mechanism and Synthesis
3150:683
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Metals in Medicine
3150:631
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Organic Chemistry I
3150:263
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Organic Chemistry II
3150:264
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Organic Chemistry Lab I
3150:265
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Organic Chemistry Lab II
3150:266
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Physical Chemistry I
3150:313
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Physical Chemistry II
3150:314
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Research Problems in Chemistry
3150:499
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ST: Analytical Chemistry
3150:710
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Spectromeric Identification of Organic Compounds
3150:670
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Transition Metal Organometallics
3150:619
Projects
Honors & Awards
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ASMS Graduate Student Travel Award
American Society of Mass Spectrometry
The ASMS Graduate Student Award recognizes graduate students whose academic achievements and current mass spectrometry research display a high level of excellence and distinction. Up to twenty awards for up to $1,000 each will be conferred annually.
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UA's SRWC Outstanding Student Member Award
University of Akron SRWC
This award recognizes the positive impact they have on themselves and the programs in which they participated by demonstrating excellence in sportsmanship and being a role model for others. To be eligible, the student must possess a minimum 2.5 grade point average and have participated in at least 3 programs throughout the year.
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Exxon Corporation Chemistry Scholarship
The University of Akron Chemistry Dept
This endowed fund was established by the Exxon Education Foundation for the purpose of providing financial assistance to junior or senior students in the Department of Chemistry. The selection of recipients is made by the faculty committee within the Department of Chemistry on the basis of academic achievement and financial need.
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Julias Muehlstein Scholarship in Chemistry
The University of Akron Chemistry Department
This award is presented to students pursuing a BS Chemistry degree who showed exemplary academics.
Languages
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English
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More activity by Savannah
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Incredible discovery shedding more light on the composition of RNA glycosylation, possible through such an amazing collaboration led by Ryan Flynn!…
Incredible discovery shedding more light on the composition of RNA glycosylation, possible through such an amazing collaboration led by Ryan Flynn!…
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Brag alert! TWO VAN ANDEL INSTITUTE GRADUATE SCHOOL students were awarded prizes for their posters yesterday at the Corewell Health Metabolomics…
Brag alert! TWO VAN ANDEL INSTITUTE GRADUATE SCHOOL students were awarded prizes for their posters yesterday at the Corewell Health Metabolomics…
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Really enjoyed the opportunity to host Steve Chen, co-founder of YouTube, at #CZBiohubCHI today with the team from the University of Illinois…
Really enjoyed the opportunity to host Steve Chen, co-founder of YouTube, at #CZBiohubCHI today with the team from the University of Illinois…
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#TeamMassSpec, one of the ideas in the recent 5-year strategy plan for the Division of Analytical Chemistry, ACS is to potentially create new…
#TeamMassSpec, one of the ideas in the recent 5-year strategy plan for the Division of Analytical Chemistry, ACS is to potentially create new…
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Today is the last day to visit us at #IMSC to talk all things #massspectrometry. Come to booth A in the Melbourne Convention and Exhibition Centre…
Today is the last day to visit us at #IMSC to talk all things #massspectrometry. Come to booth A in the Melbourne Convention and Exhibition Centre…
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Fantastic presence from Bruker at the International Society for Heart Research conference at sunny Long Beach CA. Thank you Erica Forsberg Nannan Tao…
Fantastic presence from Bruker at the International Society for Heart Research conference at sunny Long Beach CA. Thank you Erica Forsberg Nannan Tao…
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Congratulations to Benjamin Garcia at the Washington University School of Medicine in St. Louis on winning the ASBMB Ruth Kirschstein Diversity in…
Congratulations to Benjamin Garcia at the Washington University School of Medicine in St. Louis on winning the ASBMB Ruth Kirschstein Diversity in…
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