Dr. Heath Jolliff

Objective The aim of this study was to examine the relationship between state marijuana legalization and the rates of unintentional ingestions of marijuana in children younger than 6 years.

Methods This was a retrospective review of all marijuana ingestions in the National Poison Data System in children younger than 6 years between January 1, 2000, and July 31, 2017. Data analysis from NPDS included, age, sex, state and year of occurrence, clinical effects, therapies, health care… Show more

Objective The aim of this study was to examine the relationship between state marijuana legalization and the rates of unintentional ingestions of marijuana in children younger than 6 years.

Methods This was a retrospective review of all marijuana ingestions in the National Poison Data System in children younger than 6 years between January 1, 2000, and July 31, 2017. Data analysis from NPDS included, age, sex, state and year of occurrence, clinical effects, therapies, health care facility utilization, and medical outcome. Population of children younger than 6 years was obtained from the US Census Bureau. Public records search provided state legal status of marijuana and year of state marijuana legalization.

Results From 2000 through 2008, there was no significant change in the annual number or rate of ingestions of marijuana in children younger than 6 years across the United States. Following 2009, there was mean annual increase of 27% per year, rising to 742 ingestions per year or 2.98 ingestions per 100,000 population, respectively, in 2017. More than 70% of all cases occurred in states with legalized marijuana. Of all pediatric patients, 54.6% received some form of hospital-based care, of which 7.5% required critical care. Pediatric patients experienced a wide range of symptoms from drowsiness and confusion, to seizures and coma. Medical treatments ranged from hydration therapy to sedation and intubation. Poison centers safely managed 23.4% of these pediatric cases by phone, without the need for hospital evaluation.

Conclusion There was a strong association between the legalization of marijuana and ingestions of marijuana by children younger than 6 years. Show less

Our primary goal was to evaluate children ≤ 5 years of age, after exploratory ingestions of lisdexamfetamine, who were treated in Emergency Departments (EDs), or monitored at home, to determine a dose threshold that produces serious effects. The evaluation of children in EDs with nontoxic or minimally toxic ingestions is a significant cost. Whereas, monitoring these same patients at home could be a cost saving tool for hospitals and individuals. This is the first study to report the effects of… Show more

Our primary goal was to evaluate children ≤ 5 years of age, after exploratory ingestions of lisdexamfetamine, who were treated in Emergency Departments (EDs), or monitored at home, to determine a dose threshold that produces serious effects. The evaluation of children in EDs with nontoxic or minimally toxic ingestions is a significant cost. Whereas, monitoring these same patients at home could be a cost saving tool for hospitals and individuals. This is the first study to report the effects of pediatric lisdexamfetamine ingestions. Show less

OBJECTIVE: To generate national estimates of hydrocarbon-related exposures occurring in children ≤5 years of age who were treated in US emergency departments or called a regional poison control center.

Myocardial infarction is a rarely reported complication of amphetamine use. We report the case of a healthy 31-year-old man who presented to our emergency department with no clinical evidence of an acute coronary event after intravenous injection of amphetamines. However, he subsequently experienced a non-Q-wave anterior wall myocardial infarction associated with the use of amphetamines.