Navigating the complexities of biological systems requires more than just data. It demands a comprehensive approach. Each multiomics project is customized to meet your unique research goals, using cutting-edge mass spectrometry technology. The process starts with meticulous sample preparation, from extracting metabolites and lipids to protein digestion. Then comes an in-depth quantification of molecules using tried and tested LCMS methods ensuring that each type of omics data is of the highest quality. But it doesn’t stop there. The omics data is integrated with advanced bioinformatics and can be merged with other datasets like metadata or genomics studies. This holistic approach uncovers insights that might otherwise remain hidden, helping you answer the most challenging biological questions. ⬇ Learn more about our multiomics capabilities ⬇ https://lnkd.in/e_e_WWhm #Multiomics #MassSpectrometry #Bioinformatics #BoldScience
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I'm happy to announce my contribution to the textbook -Metaproteomics: Methods and Protocols-, part of the Methods in Molecular Biology series by Springer Nature. Our chapter, "Label-Free Quantitative Proteomics of Oral Microbial Communities," explores innovative techniques in this field. It was an honor to collaborate with metaproteomics experts worldwide on this project. Check it out here: [Springer Link](https://lnkd.in/ddZEVT8X) #Metaproteomics #Proteomics #MicrobialCommunities #ScientificResearch #MethodsInMolecularBiology #SpringerNature #OralMicrobiome #OralMicrobiology ---
Label-Free Quantitative Proteomics of Oral Microbial Communities
link.springer.com
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𝗛𝗼𝘄 𝗼𝘂𝗿 𝗮𝗽𝗽𝗿𝗼𝗮𝗰𝗵 𝘁𝗼 𝗺𝘂𝗹𝘁𝗶-𝗼𝗺𝗶𝗰𝘀 𝗱𝗮𝘁𝗮 𝗮𝗻𝗮𝗹𝘆𝘀𝗶𝘀 𝗮𝗹𝗹𝗼𝘄𝘀 𝗯𝗲𝘁𝘁𝗲𝗿 𝘂𝗻𝗱𝗲𝗿𝘀𝘁𝗮𝗻𝗱𝗶𝗻𝗴 𝗼𝗳 𝘁𝗵𝗲 𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝗳𝗶𝗰 𝗽𝗿𝗼𝗯𝗹𝗲𝗺𝘀 👇 What is multi-omics? Through simultaneous analysis of different omics datasets – genomics, transcriptomics, proteomics, metabolomics, microbiomics, and epigenomics – multi-omics offers a comprehensive view of biological systems and potential for deep insights into the intricate interactions within living organisms. But how? While traditional single-omics approaches may offer valuable insights, they miss the complex network of interactions governing biological processes. With multi-omics this gap can be bridged through modeling of detailed relationships between molecular components. By assessing the flow of information from one omics level to another we can obtain a more complete understanding of health, disease, and physiology and ridge the gap from genotype to phenotype. At VUGENE, we leverage sophisticated bioinformatics methods for multi-omics data integration analysis, uncovering novel biological insights and pushing the boundaries of scientific knowledge. Despite diverse noise, high heterogeneity, and non-uniformly missing data our robust computational and modeling strategies are essential to extract meaningful insights from vast data volumes. Our approach to multi-omic data empowers researchers to make groundbreaking discoveries that single-omics methods might overlook. 👩🏻💻Text authors: Milda Milčiūtė Vilija Lomeikaite, PhD Juozas Gordevicius #VUGENE #datascience #bioinformatics #multiomics #research
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Bioinformatics is an interdisciplinary science integrating genomics, transcriptomics, proteomics, and other omics data to drive innovation in drug discovery. Let's embrace this revolutionary approach to develop more effective and safer drugs for the future. Here is how Bioinformatics contributes to drug discovery. #drugdiscovery #bioinformatics #aiinbioinformatics
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🔬 New Method in Spatial Proteomics 🔬 A recent study detailed in bioRxiv (https://buff.ly/3Sv5rbH), introduces a novel high-resolution strategy for mapping the subcellular organization. This innovative method combines organelle immuno-capture with mass spectrometry, marking a significant advancement in spatial proteomics. 🌐 Key Insights: 🔵 Comprehensive Proteomic Mapping: Applied to a wide array of membranous and membrane-less compartments, this method offers an unprecedented detailed view of the subcellular proteome. 🔵 Revealing Protein Networks: Over 7,600 proteins have been mapped, revealing their subcellular localization, defining spatial protein networks, and uncovering intricate interconnections between cellular compartments. 🔍 This groundbreaking approach opens new doors in understanding the complex dynamics of cellular components and their interactions. 📢 Join the Conversation 📢 To my fellow biologists, bioinformaticians, and pharma leaders: How might this new method enhance your research? Let's discuss the potential applications and share our insights! 👇 💬 #SpatialProteomics #CellBiology #Bioinformatics #MassSpectrometry #ProteinMapping #InnovationInScience
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Assembling complete genomes directly from metagenomes is now a reality! Zymo Research has introduced its Metagenome Assembly Service, leveraging the advanced capabilities of PacBio HiFi sequencing. By harnessing the power of long-read sequencing and sophisticated bioinformatics tools, this innovative service enables researchers to meticulously analyze and reconstruct metagenomes from accurately assembled genomes or genome bins. This development significantly enhances the comprehension of metagenomes, thereby boosting the pace of scientific discoveries. “The application of long-read sequencing in metagenome assembly signifies a milestone within the field of metagenomics. Zymo Research takes great pride in pioneering this service for the benefit of the entire microbiology community. This service allows researchers to focus on scientific discovery, liberating them from the complexities of wet-lab tasks and intricate bioinformatics algorithms in metagenomics workflows." Dr. Shuiquan Tang, Director of Microbiomics at Zymo Research. Read the press release: https://lnkd.in/gizBcCF4 Learn more about Zymo Research's Metagenome Assembly Analysis Service: https://lnkd.in/g6etR8RC ------ #Metagenomics #NGS #Microbiome #Microbiology #Biotech #LifeScience
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A Game-Changer in Bioinformatics! Our latest article on Newzchain delves into how PipeBio is revolutionizing the field by providing scientists with a powerful #cloud-based platform for bioinformatics analysis. PipeBio’s platform is tailored to meet the complex needs of modern biological research, offering robust tools that enhance the ability to analyze and interpret biological data effectively. Backed by Y Combinator, their service facilitates groundbreaking discoveries in genomics, proteomics, and other critical areas of biotechnology by simplifying the computational challenges that researchers face daily. Read the full article here: https://lnkd.in/gaBfknCf #Bioinformatics #Biotech #CloudComputing #ScientificResearch #PipeBio #Genomics #Proteomics #Newzchain
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The advancements in Bioinformatics & Computational Biology are truly fascinating and hold immense potential for shaping the future of molecular biology. #Bioinformatics #ComputationalBiology #MolecularBiology #DNAAlphabets #ScienceAdvancements #ResearchInnovation #Biotechnology #Genetics #DataAnalysis #EmergingScience #ScientificDiscovery #InnovationInBiology #RNApolymerase #researchbreakthroughs
Scientists create artificial DNA that can be transcribed by a natural enzyme. Scientists at the University of California San Diego have made progress in expanding the genetic alphabet by creating artificial DNA that can be transcribed by a natural enzyme. Researchers found that RNA polymerase, a crucial enzyme in protein synthesis, was able to recognize and transcribe an artificial base pair in the same way it does with natural base pairs. The findings open up possibilities for creating custom proteins and could revolutionize how scientists approach designer proteins for therapeutic purposes. Read more: https://lnkd.in/dXPE5MUp. #dna #biotechnology #medical #research #biology
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Scientists create artificial DNA that can be transcribed by a natural enzyme. Scientists at the University of California San Diego have made progress in expanding the genetic alphabet by creating artificial DNA that can be transcribed by a natural enzyme. Researchers found that RNA polymerase, a crucial enzyme in protein synthesis, was able to recognize and transcribe an artificial base pair in the same way it does with natural base pairs. The findings open up possibilities for creating custom proteins and could revolutionize how scientists approach designer proteins for therapeutic purposes. Read more: https://lnkd.in/dXPE5MUp #dna #biotechnology #medical #research #biology
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Scientists create artificial DNA that can be transcribed by a natural enzyme. Scientists at the University of California San Diego have made progress in expanding the genetic alphabet by creating artificial DNA that can be transcribed by a natural enzyme. Researchers found that RNA polymerase, a crucial enzyme in protein synthesis, was able to recognize and transcribe an artificial base pair in the same way it does with natural base pairs. The findings open up possibilities for creating custom proteins and could revolutionize how scientists approach designer proteins for therapeutic purposes. Read more: https://lnkd.in/dXPE5MUp. #dna #biotechnology #medical #research #biology
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