Brian Loyal’s Post

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Life Science + AI + Cloud

It’s been an incredible adventure to help bring ESM3 to AWS - one of the best of my career. Huge congratulations to Alex Rives , Tom Sercu , Salvatore Candido and the rest of the team at EvolutionaryScale!

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Matt Wood Matt Wood is an Influencer

VP AI, AWS

New! Announcing new frontier biological foundation models on AWS in a collab with the amazing EvolutionaryScale. The opportunity for AI to improve health care is huge: it will be one of the biggest drivers of health and wellness improvements this decade - accelerating the momentum behind precision care, drug discovery, and biological research and development by several orders of magnitude. Today, we're bringing this reality one step closer through a collaboration with EvolutionaryScale, bringing their new "ESM3" biological AI models to everyone on AWS. Let's take a closer look… 🧬 Our biology is made up of systems - billions of vibrating, chaotic, multi-dimensional, densely-packed, beautiful, complex, interconnected systems - each one nudging countless others to stay in balance with one another. 🩵 AI offers perhaps the largest opportunity in a generation to build new ways of understanding and simulating these chaotic systems, allowing us to precisely manage them and tip the scales in favor of health and wellness. 🌤️ Today, we are announcing a partnership with EvolutionaryScale, and the availability of new cutting edge “ESM3” biological AI on AWS. 💭Just how LLMs learn to understand the relationships between words and topics, and can interpret a prompt to express them in different modalities, so ESM3’s AI models learn to understand relationships between sequence, structure and function, and can interpret a prompt to express them in different modalities. 💬 ESM3 can reason over the sequences, structures, and functions of proteins to generate new protein structures - with atomic level accuracy - which "fit" within the complex, multi-dimensional systems of real biology while meeting the precise functional requirements of the prompt. 🙌 Using models like these, there is an opportunity to speed up drug development by designing active molecules more quickly and efficiently, create more personalized treatments, drive down antibiotic resistance, improve diagnostics and disease detection (especially for rare diseases), create new vaccines, and improve chronic disease management. 🫀 Over time, these models will not only understand how biological molecules function together, but also… …how cells interact with other cells in tissues… …how tissues interact with other tissues in organs… …and how our organs interact with each other in our own bodies… …leading the way for sophisticated new ways to find health and wellness through balance. It'll take a beat, but it's a very exciting, promising new area. ESM3 is available on SageMaker and HealthOmics today, so it can be incorporated into health and life sciences drug discovery workflows immediately. We'll also add ESM3 to Bedrock later this year. Fire it up and prompt healthy. PS: Below, a new fluorescent protein designed by ESM3. It has the same function as the protein which makes some coral glow, but in an entirely new sequence - more novel than it is similar to existing proteins.

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Yusuf Azizullah

CEO, GBAC | BoardroomEducation.com Accreds | WEF Thought Leader | Board, Audit Committee | Qualified Investor | AI/Cloud Gov | Public Co. Board Exp; NYSE, NASDAQ, TSX, LSE. ASX

1mo

Congrats to Tom Sercu , Salvatore Candido on the $142 million funding , what is exciting among others things for innovation , AWS SageMaker will debiase the data and analytics for a more health equity! All the best disrupting !

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Yanjun (Jane) Qi

Professor / Senior Manager / Principal Applied Scientist /AWS Bedrock

2mo

Kudos to Brian.. this is great

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