In this research article, the proteomes of more than 3000 individual nuclei have been analyzed to identify regulators of nucleoplasmic protein transport in macrophages, linking functional variability to proteome variability. Learn more: https://lnkd.in/e6t74V4B #massspectrometry #proteomics #timsTOF #TIMS
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The precision of the SomaScan Assay has been maintained or improved across all assay versions, up to and including the most recent release covering 11,000 proteins. This can be measured using the coefficient of variation, which is a powerful tool to compare performance across proteomics platforms. Lower CVs are more favorable and are an indicator of assay reproducibility. Nature's recent published correction to a previous study is important to us, supporting our belief that the SomaScan Platform is leading the industry with dependably low coefficients of variation. You can read the correction here: https://lnkd.in/gc3Q_ctu
Author Correction: Large-scale plasma proteomics comparisons through genetics and disease associations - Nature
nature.com
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The precision of the SomaScan Assay has been maintained or improved across all assay versions, up to and including the most recent release covering 11,000 proteins. This can be measured using the coefficient of variation, which is a powerful tool to compare performance across proteomics platforms. Lower CVs are more favorable and are an indicator of assay reproducibility. Nature's recent published correction to a previous study is important to us, supporting our belief that the SomaScan Platform is leading the industry with dependably low coefficients of variation. You can read the correction here: https://lnkd.in/gc3Q_ctu
Author Correction: Large-scale plasma proteomics comparisons through genetics and disease associations - Nature
nature.com
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The precision of the SomaScan Assay has been maintained or improved across all assay versions, up to and including the most recent release covering 11,000 proteins. This can be measured using the coefficient of variation, which is a powerful tool to compare performance across proteomics platforms. Lower CVs are more favorable and are an indicator of assay reproducibility. Nature’s recent published correction to a previous study is important to us, supporting our belief that the SomaScan Platform is leading the industry with dependably low coefficients of variation. You can read the correction here: https://lnkd.in/gc3Q_ctu
Author Correction: Large-scale plasma proteomics comparisons through genetics and disease associations - Nature
nature.com
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The precision of the SomaScan Assay has been maintained or improved across all assay versions, up to and including the most recent release covering 11,000 proteins. This can be measured using the coefficient of variation, which is a powerful tool to compare performance across proteomics platforms. Lower CVs are more favorable and are an indicator of assay reproducibility. Nature's recent published correction to a previous study is important to us, supporting our belief that the SomaScan Platform is leading the industry with dependably low coefficients of variation. You can read the correction here: https://lnkd.in/gc3Q_ctu
Author Correction: Large-scale plasma proteomics comparisons through genetics and disease associations - Nature
nature.com
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The precision of the SomaScan Assay has been maintained or improved across all assay versions, up to and including the most recent release covering 11,000 proteins. This can be measured using the coefficient of variation, which is a powerful tool to compare performance across proteomics platforms. Lower CVs are more favorable and are an indicator of assay reproducibility. Nature's recent published correction to a previous study is important to us, supporting our belief that the SomaScan Platform is leading the industry with dependably low coefficients of variation. You can read the correction here: https://lnkd.in/gc3Q_ctu
Author Correction: Large-scale plasma proteomics comparisons through genetics and disease associations - Nature
nature.com
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If you want to see the power of a great technology check this out! This is just another example on what can be achieved by researchers choosing the best technology for their application rather than the one everybody talks about…. Microarrays are still an amazing tool, outperforming other technologies on sensitivity, reproducibility and dynamic range
The precision of the SomaScan Assay has been maintained or improved across all assay versions, up to and including the most recent release covering 11,000 proteins. This can be measured using the coefficient of variation, which is a powerful tool to compare performance across proteomics platforms. Lower CVs are more favorable and are an indicator of assay reproducibility. Nature’s recent published correction to a previous study is important to us, supporting our belief that the SomaScan Platform is leading the industry with dependably low coefficients of variation. You can read the correction here: https://lnkd.in/gc3Q_ctu
Author Correction: Large-scale plasma proteomics comparisons through genetics and disease associations - Nature
nature.com
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Trent Paul in lab published a new paper on Protein Science. In this paper, we elucidate how U1-70K interacts with SRSF1, and how this interaction is regulated by phosphorylation of the two proteins. This work provides new insight into the early stages of spliceosome assembly. https://lnkd.in/eKNb2uwY
The U1‐70K and SRSF1 interaction is modulated by phosphorylation during the early stages of spliceosome assembly
onlinelibrary.wiley.com
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As a SDS-PAGE-based high-throughput proteomics assay, GAPPIS enables whole-proteome molecular weight measurements, and expression analysis. GAPPIS is powerful for identifying protein cleavages and studying a wide range of biological processes.
Gel-Assisted Proteome Position Integral Shift Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Caspase 3 Substrates
pubs.acs.org
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Unlock the power of #Peptidomics with our cutting-edge techniques! Discover the intricacies of peptide molecules in biological samples. Our mass spectrometry methods ensure precise identification and quantification, advancing #BiomedicalResearch, #BiomarkerDiscovery, and #DiseaseDiagnosis. Dive deeper: https://lnkd.in/geYDvgj5 #MassSpectrometry #Proteomics #PeptideAnalysis
Peptidomics Analysis, Peptidomics Methods and Strategies, Analysis of Peptides | INOMIXO
inomixo.com
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Sub single cell proteomics from Prof. Slavov's group. Now single cell level is not enough, we want to see which proteins are regultors and most importent, they functions 😁 . So here Prof. Slavov still use plexDIA method on timsTOF SCP to monitor protein changes in single nucleus~. Since this is timsTOF SCP, we are looking forward to result on tims Ultra 2~ 😃
Single-nucleus proteomics identifies regulators of protein transport
biorxiv.org
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