COPD Foundation’s Post

This World Liver Day, Briota Technologies is proud to announce its involvement in the NCD Diseases Elimination Program, dedicated to eradicating Non-Communicable Diseases (NCDs) globally. As we commemorate #WorldLiverDay, it's crucial to recognize the significance of liver health in our overall well-being. The liver plays a vital role in our body's metabolic processes, and maintaining its health is essential for a vibrant life. At Briota Technologies, we are committed to leveraging cutting-edge technology and innovative solutions to combat NCDs, including liver diseases. Through our NCD Diseases Elimination Program, we aim to raise awareness, provide resources, and implement preventive measures to promote liver health worldwide. Join us in our mission to #beatNCDs and create a healthier future for generations to come. Let's pledge to prioritize our liver's well-being through healthy choices and lifestyle practices. Together, we can make a difference and build a world where everyone can thrive. #WorldLiverDay #SwasthaBharat #Liverhealth #beatNCDs स्वस्थ लिवर, स्वस्थ जीवन की कुंजी है। इस विश्व लिवर दिवस पर, हम सभी को लिवर की सेहत के महत्व को समझना और इसे सुरक्षित रखने के लिए कदम उठाने की आवश्यकता है। #WorldLiverDay #SwasthaBharat #Liverhealth #beatNCDs Briota Technologies Briota ApS American Association for the Study of Liver Diseases (AASLD) Inserm Institute for Translational Medicine and Liver Disease, University of Strasbourg European Foundation for the Study of Chronic Liver Failure (EF CLIF) Canadian Association for the Study of the Liver

🔔[Congress]🔔 Here it is, the complete presentation of our CSO Benjamin Lelouvier at «7èmes JOURNEES SCIENTIFIQUES FRANCOPHONES du Club Alzheimer de Montpellier». This presentation is about applications of the microbiome beyond the gut, through 2 exciting projects: -Microbiome variations in Alzheimer’s Disease (the MICMALZ project) -Alterations of the skin microbiota by tick bites 👉To watch the video (in French): https://lnkd.in/eNmUT3HZ #Alzheimer #Microbiome #neurodegenerative diseases #alzheimersdisease

Dermal injury drives a skin to gut axis that disrupts the intestinal microbiome A study has discovered that skin damage can significantly impact the gut's microbiome and immune response in mice. When the skin is injured or experiences specific changes, such as the breakdown of hyaluronic acid (a component of the skin), this triggers changes in the gut. Researchers observed increased expression of certain genes related to the body's defense mechanisms in the colon, alongside alterations in the composition and behaviour of gut bacteria. These findings demonstrate a direct "skin-gut axis," showing how skin damage can disturb intestinal homeostasis and modify the gut microbiome. This interaction was illustrated by experiments where skin damage led to an increased risk of colitis (inflammation of the colon), a condition that could be mitigated by oral antibiotics or by transferring the gut microbiome from affected mice to healthy ones. This research highlights a novel communication pathway between the skin and the gut, emphasising the interconnectedness of body systems and the complex role of the microbiome in health and disease. Link to Study:https://lnkd.in/gsxXRK3x #microbiome #guthealth #gutskinaxis

Cellular neighborhoods in the healthy and inflamed gut Cells within the intestines perform various roles including nutrient absorption, sensing, and maintaining homeostasis. Certain chronic disorders are distinctly characterized by gut inflammation, which disrupts intestinal cells and can lead to a remodeling of the gut and the introduction of new immune cells. To better understand the types of cells and their positioning within the intestines, researchers used a new technique known as MERFISH (multiplexed-error robust-fluorescence in situ hybridization) to analyze 940 genes in 1.35 million intestinal cells in a mouse model of colitis. They identified cell populations associated with healthy and inflamed states, mapped their spatial neighborhoods, and traced the evolution of these populations during the inflammation process. One significant cell type to note was fibroblasts, that, when in a distressed state, can induce inflammation associated fibroblasts (IAFs), which may help remodel extracellular matrixes, recruit immune cells, and produce inflammatory cytokines. #ScienceMission #ScienceNEwsHighlights https://lnkd.in/gJh_Mamw

🌟✨ Reflecting on the first day of the World Congress of Inflammation from the IAIS in Québec ! ✨🌟 Organized by the International Association of Inflammation Societies (IAIS), under the leadership of Dr. Jason McDougall, President, and the Local Organizing Committee chaired by Dr. Marc Pouliot, Université Laval, the congress promises to be a resounding success ! The day kicked off with an extraordinary keynote lecture by Pr. Paul Kubes from the University of Calgary, titled "Homeostasis: Just a level of inflammation." Pr. Kubes introduced us to the concept of immunophysiology, explaining how the immune system integrates with tissues to maintain homeostasis and how its disruption leads to inflammation. His insights into the roles of alveolar macrophages in the lungs and Kupffer cells in the liver were truly enlightening. 🌟✨ Highlights from the WCI Symposium on Lung Inflammation ! ✨🌟 Following the inspiring keynote lecture by Pr. Paul Kubes, the "Novel Points of Control of Lung Inflammation" symposium, sponsored by GREMI, the French Society of Inflammation, and Ambiotis, delved into groundbreaking advancements in lung inflammation research. Chaired by Dr. Véronique Witko-Sarsat and Dr. Mustapha Si-Tahar, the session featured: 🔬 Effect of CFTR modulators on lung inflammation and neutrophil functions in cystic fibrosis by Dr. Véronique Witko-Sarsat 🔬 Neonatal cross-talk of alveolar macrophages and neutrophils regulating lung inflammation by Dr. Erwan Pernet 🔬 Metabolic control of virus-induced lung inflammation by Mustapha Si-Tahar 🔬 Specialized pro-resolving mediators in respiratory diseases by Prof. Bruce Levy Each speaker brought forth innovative insights and unveiled promising pathways for therapeutic breakthroughs, leaving us inspired and hopeful for the future of respiratory health. A heartfelt thank you to all the speakers and participants for making this session an incredible success! 🎉 #WCI #GREMI #LungInflammation #RespiratoryHealth #neutrophil #macrophage #cysticfibrosis #INSERM #InstitutCochin #CFTR #VirusInflammation #TherapeuticBreakthroughs

The oral cavity is one of the most diverse microbiomes in the human body, sustaining hundreds of different species. Oral microbes can migrate to various areas of the body, known as dysbiosis. Here, we explore the consequences of oral dysbiosis and how it can increase the pathogenesis of certain diseases. Learn more: https://brnw.ch/21wH8wq #openscience #openaccess #oralhealth

Dermal injury drives a skin-to-gut axis that disrupts the intestinal microbiome A study has discovered that skin damage can significantly impact the gut's microbiome and immune response in mice. When the skin is injured or experiences specific changes, such as the breakdown of hyaluronic acid (a component of the skin), this triggers changes in the gut. Researchers observed increased expression of certain genes related to the body's defense mechanisms in the colon, alongside alterations in the composition and behavior of gut bacteria. These findings demonstrate a direct "skin-gut axis," showing how skin damage can disturb intestinal homeostasis and modify the gut microbiome. This interaction was illustrated by experiments where skin damage led to an increased risk of colitis (inflammation of the colon), a condition that could be mitigated by oral antibiotics or by transferring the gut microbiome from affected mice to healthy ones. This research highlights a novel communication pathway between the skin and the gut, emphasising the interconnectedness of body systems and the complex role of the microbiome in health and disease. Link to Study:https://lnkd.in/gsxXRK3x

Parkinson's Onset and the Link to Gut Bacteria: Unveiling the Role of Opportunistic Bacterial Pathogens Recent research is revolutionizing our understanding of Parkinson's Disease, indicating that the gut may be a key player in the onset of this neurodegenerative condition. Notable studies Dr. HAYDEH PAYAMI in Nature have revealed a significant link between an excess of opportunistic pathogens in the gut — some of these include E. coli and Klebsiella species — and the development of Parkinson's Disease. These bacteria usually coexist harmlessly within our digestive system but can become harmful under certain conditions, such as a weakened immune system. The findings suggest that for individuals with Parkinson's Disease, these pathogens may be a crucial factor in triggering the disease. This supports the hypothesis that Parkinson's could originate in the gut and subsequently affect brain function and health. Dr. HAYDEH PAYAMI groundbreaking study utilized deep shotgun sequencing of fecal DNA from Parkinson's Disease patients and control groups. This method identified unique microbial patterns and significant imbalances in the gut microbiome of those with Parkinson's Disease, providing compelling evidence of the disease's potential gut origins. These discoveries underscore the critical role of gut health, not only for digestion but also for its extensive influence on neurological well-being. As we delve deeper into the complexities of the human microbiome, these findings offer renewed hope and pathways for treatment for millions impacted by Parkinson's globally. Image and sources: https://lnkd.in/es9FsKdy https://lnkd.in/d6S3qK4J #ParkinsonsDisease #GutHealth #Microbiome #HealthInnovation

🔍📑 New research shows virtual chromoendoscopy as a promising alternative to dye-spraying chromoendoscopy in detecting lesions and dysplasia in long-standing inflammatory bowel disease. Comparable performance indicates potential for enhanced screening. https://lnkd.in/d9WaMuz6 #IBD #Gastroenterology #MedicalResearch #TurkishJournalofGastroenterology #TJG #GastroenterologyResearch #MedicalJournals #GastrointestinalResearch #November #NewIssue

Agarikon mushroom supports immunity, has antiviral and antibacterial benefits, and may help fight cancer. It promotes respiratory health, acts as an antioxidant, and enhances mental well-being, serving as a holistic remedy for health challenges. #agarikon #MedicinalMushrooms #ImmuneSupport #antiviral #antibacterial #antiinflammatoryfood #respiratoryhealth #antioxidants #anticancerpotential #mentalwellbeing