DEEPSYNC’s Post

Pioneering Biomimetic Neuroprosthetics: A Leap Forward in Restoring Sensation and Mobility Researchers at the ETH Zurich Neuroengineering Lab, led by Professor Stanisa Raspopovic, have unveiled groundbreaking advancements in neuroprosthetics. Their innovative prosthetic legs, equipped with biomimetic stimulation technology, allow amputees to experience natural sensations for the first time. Unlike conventional prostheses, which often induce artificial and unpleasant sensations, this new approach mimics the body's natural neural responses. 🦿💡 By connecting prosthetic limbs to the sciatic nerve via implanted electrodes, the neuroprosthesis establishes direct communication with the brain, enabling the transmission of real-time feedback about pressure and movement. 🧠⚡ Reference: Biomimetic computer-to-brain communication enhancing naturalistic touch sensations via peripheral nerve stimulation” by Giacomo Valle, Natalija Katic Secerovic, Dominic Eggemann, Oleg Gorskii, Natalia Pavlova, Francesco M. Petrini, Paul Cvancara, Thomas Stieglitz, Pavel Musienko, Marko Bumbasirevic and Stanisa Raspopovic, 20 February 2024, Nature Communications #biomedicalengineering #upf #upfcomunicació #engineering #pompeufabra #bioengineering #technews

A team from Chalmers, Université de Fribourg - Universität Freiburg, and the Netherlands Institute for Neuroscience has made a breakthrough in vision implants. They’ve developed a tiny, durable implant with neuron-sized electrodes, holding immense promise for future vision restoration. The implant is a thread-like structure with multiple electrodes in a row, each representing a pixel. This could revolutionize how the visually impaired perceive images, making it more detailed. Crafted from flexible, non-corrosive materials, the implant can last longer in the body, overcoming challenges of corrosion and rigidity seen in older technologies. “Miniaturisation of vision implant components is essential. Especially the electrodes, as they need to be small enough to be able to resolve stimulation to large numbers of spots in the ‘brain visual areas’. The main research question for the team was, ‘can we fit that many electrodes on an implant with the materials we have and make it small enough and also effective?’ and the answer from this study was – yes,” says Professor Maria Asplund, who led the technology development part of the project and is Professor of Bioelectronics at Chalmers. This groundbreaking work paves the way for developing implants with thousands of electrodes, significantly enhancing the image resolution for users.  Read more: https://lnkd.in/d-6UP_Ea #VisionImplants #Bioelectronics #Innovation #Neuroscience

Latest news about Zhuoliang He's latest publication on Advanced Science. 👏👏👏

FULL Ep. 7 | Paula Vilarinho - Advanced Biomems for Tissue Engineering: Application in Hard Tissues CICECO SPOTLIGHT IS OUT! Researcher Paula Vilarinho, along with her team, discovered that polymeric piezoelectric coatings might decrease the rejection rates of metallic implants. The device, which was targeted for bone tissue regeneration, can also be used in, for example, neuronal regeneration. So there's a pipeline of applications that would be explored in the future. https://lnkd.in/dBTMym5Q

Curious about how researchers at Harvard University are developing plant-derived sealants to treat corneal injuries? A recent study by Harvard's Laboratory of Adaptive and Regenerative Biology has been exploring the biomechanics of a plant-derived sealant, in order to understand the sealant's ability to provide a secure and stable seal for corneal injuries. The researchers used a Texture Analyser to assess and optimise the mechanical properties of the sealant, such as measuring the adhesive strength and viscosity of the sealant which provided valuable insights into its effectiveness. Overall the research provides crucial information about the biomechanical properties of the sealant, which could lead to advancements in the treatment and management of corneal injuries. Read more: https://bit.ly/47c9s9B | See which instrument they used: https://bit.ly/2K3wlqI

I am delighted 😊 to share an article we have published in IOPScience in which we developed a full-head model of a virtual patient implanted with a cochlear implant (CI). Cochlear and head tissues were segmented and post-processed based on µCT and MR images derived from open repositories. We created the full-head model and simulated intra and extracochlear electric fields upon stimulation of different electrodes (apical, medial, and basal) and CI modes (monopolar, bipolar, tripolar, and partial tripolar), as well as for different tissue conductivity values. This study also places special emphasis on the analysis of the electric field in the facial nerve, hopefully for a better understanding of the underlying bioelectrical mechanisms of facial nerve stimulation. 👩🎓 You can take a look at the article in DOI: https://lnkd.in/dTiD98wF 👉 👉 Note: We have made the complete model available for the CI community on ZENODO for further use in research and teaching (https://lnkd.in/dVjuc_gH) 🤙 Our group is now working on developing a pipeline for the electrical simulation of full-head models and their validation based on images and clinical data in real CI patients. Manuel Lazo, Attila Fráter, Francisco Ropero Romero, Serafín Sánchez Gómez, Javier Reina-Tosina #iopscience #NewArticle #PMB #CochlearImplant #modelling #cochlea #MRI #CT #fullhead #bioelectricity #openaccess #zenodo #FacialNerve #FEM #bioengineering #physics #medicine #audiology #ORL

See the whole body or get organ-specific. Visualize and quantify both ultrasound and photoacoustic signals from the entire mouse body or select areas of interest—Macro to Micro! Learn more about the Vevo F2 LAZR-X by visiting https://lnkd.in/gzhEGay #seeingmorematters #visualsonics #VevoF2 #hightolowfrequency #ultrasound #imaging #research #science #photoacoustics

📢 We have a new paper out dealing with corneal tissue engineering!🔬🧪 In this study recently published in the Journal of Materials and Design #TeamBioEngine and friends have developed a groundbreaking ultrathin, tough and super flexible biomaterial using a decellularized amniotic membrane (AM) coated with Polydimethylsiloxane (PDMS). This innovative approach has resulted in a eye membrane with improved mechanical behavior, transparency, and reduced degradation rate. Through in vitro and in vivo evaluations, we have demonstrated remarkable biomechanical, biological, and antibacterial properties. Specifically, in a rabbit model, the application of the AM/PDMS membrane on corneal defect wounds showed enhanced corneal tissue healing and improved epithelial cell morphology. 🐇 Our research opens new possibilities for more effective and efficient treatments in ocular injury cases, bringing hope for a brighter future in eye care. Link to paper: https://lnkd.in/dXQkEXMh #tissueengineering #biomaterials #eyecare #cornealtissue #celltherapy #flexiblematerials Mazaher Gholipourmalekabadi DTU Health Tech DTU - Technical University of Denmark

New Publication Glad to share our research work published in the journal Molecular Simulation. In this work, we conducted systematic nanotribological investigation employing Molecular Dynamics simulations to unravel the nanofriction behavior and its velocity dependence at the articular cartilage soft interfaces under extreme conditions (a combination of higher loads and sliding velocities). Analysis conducted at high velocity in a simplified tissue-like hydrated environment revealed that articular cartilage can resist heavy deformation and exhibit low frictional properties by means of even a structured monolayer of water entrained at the interface. This study provides mechanistic insights into friction mechanisms at the cartilage interface which could lead to wear-like conditions under physiological sliding contact conditions. Also, it is evident from this work how nanoscale mechanisms at collagen-water interface would serve as new bio-inspirations for developing smart mechanical solutions for various applications. You can read the full paper here. Open for research collaborations. https://lnkd.in/dKpnjTZq #publication #nanomechanics #biotribology #softmatter #molecularsimulations

A research team from the Department of Materials Science and Engineering (DMSE) at the Korea Advanced Institute of Science and Technology (KAIST) have developed a biomimetic scaffold to aid the growth of bone tissue. The piezoelectric scaffold utilises the osteogenic ability of hydroxyapatite to generate electrical signals when pressure is applied and demonstrated potential for promoting bone regeneration through in vitro and in vivo experiments in rats. Learn more in Technology Networks: https://rb.gy/2yqqfu #Bioengineering #MaterialsScience