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[INNOVATION UPDATE] WHIM Syndrome is named for its symptoms that include warts, hypogammaglobulinemia, infections, and myelokathexis (a disorder causing low levels of white blood cells). In patients with WHIM, an overactive receptor known as CXCR4 causes mature blood cells to be retained in the bone marrow preventing their participation in immune system functions. Mavorixafor (Xolremdi) is a small molecule inhibitor of CXCR4 that was recently approved by the US Food and Drug Administration to boost circulating white blood cells in patients with WHIM Syndrome. Learn more about this innovative treatment in the latest Emerging Health Care Innovation Brief: https://hubs.la/Q02DBNJs0 #whim #rarediseases #immunodeficiency #patientcare #healthcare #innovation #horizonscanning #ecri

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