Ilja Boone’s Post

Ophthopedia Update:Natural History of Optic Disc With Physiologic Large Cup: Incidence, Predictors of Glaucoma Conversion After Minimum 10-Year Follow-up: To investigate the natural history of optic disc with physiologic large cup (PLC) (ie, vertical cup/disc ratio [VCDR] ≥0.6 without retinal nerve fiber layer defect) and the risk factors for glaucoma conversion. #Ophthalmology #Ophthotwitter #Scicomm

“We want to use a more objective measure to quantify patient’s inflammation.” - Edmund Tsui, MD In this video interview at ARVO 2024, Edmund Tsui, MD, presents an overview of his team's research using swept-source OCT with the ANTERION® platform to look at anterior chamber cells in patients with uveitis. Using an in-house customized algorithm, his team identified the number of cells in each patient, which they found correlated very well with the standardization of uveitis nomenclature or SUN clinical grading. Based on the results, Dr. Tsui suggests that swept-source anterior segment OCT offers practitioners an opportunity to have a high-resolution, reproducible, objective, and quantifiable method to quantify anterior chamber inflammation. See the full interview here: https://lnkd.in/e25zcJdV Edmund Tsui, MD, MS #ANTERION #HeidelbergEngineering #HeidelbergEngineeringUS #ARVO2024 #OCT #uveitis #ophthalmology

From Mashable Science: New implant can track the health of organ transplants in real time https://bit.ly/45QEJP9

Absolutely, Linda Griffith! It's truly astonishing how little we know about the science behind conditions like #endometriosis and #adenomyosis, which impact so many women. We can't accept this status quo any longer. It's high time for innovative therapies and diagnostics. Women have waited far too long. Thanks to leaders like you we are asking the harder questions to change this reality. Your Open Endoscopy Forum Gynecology Science and Technology Workshop this Friday, Sept. 22 is a great start: https://cgr.mit.edu/oef/ 💥Not so fun facts that fire me up: Endometriosis affects 1 in 10 women. ⭐️ The estimated US economic burden is a staggering $78–119 billion annually. ⭐️ Women often wait 8 to 12 years for a diagnosis. ⭐️ Black women are 50% less likely to be diagnosed compared to white women. Adenomyosis affects 1 in 5 women. ⭐️ Rates are approximately 60% higher in black women compared to white women. ⭐️ While the economic burden lacks a reliable statistic, it's undoubtedly BIG. ⭐️ There are no approved medical guidelines or therapeutic treatments, with the "gold standard" being hysterectomy. We urgently need forums that encourage dialogue and collaboration among all stakeholders, and MIT could be the catalyst for this change. Let's roll up our sleeves and make it happen! 💪🔬 #CollaborationMatters #WomensHealth

 I am very pleased to announce the publication of my latest research paper and would like to thank all co-authors for their valuable contributions. 🧬 In this work, we investigated the role of BMP9 on vascular homeostasis and endothelial cell identity. We show that BMP9 is required for the correct identity of liver endothelial cells and that its loss leads to dilated vascular vessels in multiple organs (liver, brain, kidney, lung). We have also demonstrated for the first time that BMP9 deletion is sufficient to induce arteriovenous shunting and malformations, reminiscent of what can be observed in HHT patients. Overall, we demonstrate that BMP9 plays a key role in the pathogenesis of HHT. ⬇️ if you want to know more, follow the link : https://lnkd.in/dESH4Aux Authors A Desroches-Castan, D Koca, H Liu, C Roelants, L Resmini, N Ricard, C Bouvard, N Chaumontel, P L Tharaux, E Tillet, C Battail, O Lenoir, S Bailly  #endothelialcells #vasculardiseases #raredisease #HHT #PAH #ResearchPublication 

Curious about the best strategies for fluid management in acute and acute-on-chronic liver failure? Discover evidence-based tips and hemodynamic optimization techniques in our latest chapter! 💧 📚 ➡ Fluid Management in Liver Failure In this chapter, fluid management in both acute and acute-on chronic liver failure is discussed. For each pathology, the specific hemodynamic alterations are first described and followed by some general and specific considerations during hemodynamic optimization and evidence-based guidance in the choice of fluids. 💙 Get the book "Rational Use of Intravenous Fluids in critically Ill Patients": https://lnkd.in/efRWnPR8 🔎 Discover our free members portal: https://lnkd.in/eYNzTE_A 📑 PDF: https://lnkd.in/ePH3Gkye

From Mashable Science: New implant can track the health of organ transplants in real time https://bit.ly/45PvsXA

📣 A new paper published by Gelu M. Breaza et al. "Pancreaticoduodenectomy with Anatomical Vascular Variant in Groove Pancreatitis—A Case Report" 🔗Read the full paper at: https://lnkd.in/djyF4cPi 👉 This article belongs to the Special Issue: "Updates on Pancreatic Diseases: A Surgical and Multidisciplinary Approach", https://lnkd.in/djUN-7Z2 #pancreas #pancreatitis

WHITE DOT SYNDROME (MEWDS) - In 1984 Jampol et aldescribed a new posterior uveitis, which they named multiple evanescent white dot syndrome (MEWDS). - The disease occurred in young people (mean age 28 years), predominantly women (90%). - characterized by unilateral, 100 to 200 μm gray-white dots at the level of the retinal pigment epithelium or outer retina and a foveal granularity. - The disease spontaneously remitted over ~2 months with recovery of normal or near normal (20/30 or better) acuity in all cases. - No systemic disease was evident, and no treatment appeared warranted. Am J Ophthalmol. Author manuscript; available in PMC 2022 Aug 1.Published in final edited form as:Am J Ophthalmol. 2021 Aug; 228: 198–204. Published online 2021 Apr 15. doi: 10.1016/j.ajo.2021.03.050 #uveitis #whitedotsyndrome #MEWDS

Tracheobronchopathia osteochondroplastica: a case report highlighting the importance of clinico-radiologic correlation https://lnkd.in/dvdT-d9i