Phosphorylated Peptides: A Key Figure in Biological Processes https://lnkd.in/eHfrQVPv
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The former 1B48 nucleic acid extractor is designed to specifically adsorb nucleic acid molecules in various samples using magnetic beads. By utilizing the movement of magnetic rods in different holes, the instrument efficiently transfers the magnetic beads to achieve the purification of nucleic acid molecules. This extractor is capable of automatically extracting nucleic acid from a range of sources including whole blood, bacteria, plasmid, virus, serum free, and plant samples. Its versatility makes it a valuable tool in scientific research, CDC activities, food safety assessments, clinical testing procedures, forensic medicine applications, and other relevant fields. Features: - Intelligence: Preset 8 groups of programs, editable for storing 100 groups of programs - Efficiency: 10 to 40 mins to complete (Determined by reagent used), 48 samples were extracted - Flexibility: multiple operation modes, temperature control, freely programming, flexible operation - Compatibility: compatible with various manufacturers’ reagents for DNA extractor - Safety: UV Disinfect, the safety doors automatically open for protection function For more information, please visit 👉 https://lnkd.in/dgpRERss Or contact our sales team at 👉 [email protected] “We are redefining science through innovative biotech solutions “ #automatedDNAextractor #innovativetech #Nanjing superyears Gene Technology Co.,ltd.
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The former 1B48 nucleic acid extractor is designed to specifically adsorb nucleic acid molecules in various samples using magnetic beads. By utilizing the movement of magnetic rods in different holes, the instrument efficiently transfers the magnetic beads to achieve the purification of nucleic acid molecules. This extractor is capable of automatically extracting nucleic acid from a range of sources including whole blood, bacteria, plasmid, virus, serum free, and plant samples. Its versatility makes it a valuable tool in scientific research, CDC activities, food safety assessments, clinical testing procedures, forensic medicine applications, and other relevant fields. Features: - Intelligence: Preset 8 groups of programs, editable for storing 100 groups of programs - Efficiency: 10 to 40 mins to complete (Determined by reagent used), 48 samples were extracted - Flexibility: multiple operation modes, temperature control, freely programming, flexible operation - Compatibility: compatible with various manufacturers’ reagents for DNA extractor - Safety: UV Disinfect, the safety doors automatically open for protection function For more information, please visit 👉 https://lnkd.in/dgpRERss Or contact our sales team at 👉 [email protected] “We are redefining science through innovative biotech solutions “ #automatedDNAextractor #innovativetech #Nanjing Superyears Gene Technology Co.,Ltd
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The former 1B48 nucleic acid extractor is designed to specifically adsorb nucleic acid molecules in various samples using magnetic beads. By utilizing the movement of magnetic rods in different holes, the instrument efficiently transfers the magnetic beads to achieve the purification of nucleic acid molecules. This extractor is capable of automatically extracting nucleic acid from a range of sources including whole blood, bacteria, plasmid, virus, serum free, and plant samples. Its versatility makes it a valuable tool in scientific research, CDC activities, food safety assessments, clinical testing procedures, forensic medicine applications, and other relevant fields. Features: - Intelligence: Preset 8 groups of programs, editable for storing 100 groups of programs - Efficiency: 10 to 40 mins to complete (Determined by reagent used), 48 samples were extracted - Flexibility: multiple operation modes, temperature control, freely programming, flexible operation - Compatibility: compatible with various manufacturers’ reagents for DNA extractor - Safety: UV Disinfect, the safety doors automatically open for protection function For more information, please visit 👉 https://lnkd.in/dgpRERss Or contact our sales team at 👉 [email protected] “We are redefining science through innovative biotech solutions “ #automatedDNAextractor #innovativetech #Nanjing superyears Gene Technology Co.,ltd.
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"The conditions that led to the formation of the first organisms and the ways that life originates from a lifeless chemical soup are poorly understood. . . . We now show how the interplay between these compound classes [amino acids and nucleobases] can give rise to new self-replicating molecules using a dynamic combinatorial approach. We report two strategies for the fabrication of chimeric amino acid/nucleobase self-replicating macrocycles capable of exponential growth. . . . [S]elf-replication in the present systems start from units containing only a single nucleobase. Self-replication is accompanied by self-assembly, spontaneously giving rise to an ordered one-dimensional arrangement of nucleobase nanostructures."
Spontaneous Emergence of Self-Replicating Molecules Containing Nucleobases and Amino Acids
pubs.acs.org
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Czech Republic: Terpenes and Terpenoids Conjugated with BODIPYs: An Overview of Biological and Chemical Properties
Terpenes and Terpenoids Conjugated with BODIPYs: An Overview of Biological and Chemical Properties
pubs.acs.org
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Pakistan: Recent synthetic strategies for N-arylation of pyrrolidines: a potential template for biologically active molecules
Recent synthetic strategies for N-arylation of pyrrolidines: a potential template for biologically active molecules - Molecular Diversity
link.springer.com
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Thrilled to share a new comprehensive review article from Prof. Brajendra Singh group recently published in the journal Synthesis as part of the Special Issue on Emerging Trends in Glycoscience. This review covers work the latest advancements in the synthesis of spirocyclic nucleosides - a fascinating class of sugar-modified compounds with important biological activities. The review covers the various strategies developed over the past decades to access different types of spirocyclic nucleosides, including those functionalized at the C-1', C-2', C-3' and C-4' positions of the sugar moiety. These conformationally restricted nucleoside analogues have shown promise as potential therapeutics, with applications in areas like antiviral, anticancer, and plant growth regulation. Some key highlights from the review: Comprehensive coverage of synthetic methodologies for diverse spirocyclic nucleoside scaffolds Discussion of the potential biological and conformational impacts of the spirocyclic modification Insights into the synthetic challenges and approaches used to overcome them Check out the full article for all the details: https://lnkd.in/g8VzCYuG #glycoscience #nucleosides #organicsynthesis #drugdiscovery #medicinalchemistry SYNTHESIS Journal Vivek Sharma
Advances in the Synthesis of Spirocyclic Nucleosides
thieme-connect.com
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Here Donndelinger et al describes a novel application of charge Inversion Ion/Ion Reaction and Electron Capture Dissociation (ECD) for phosphopeptide sequencing via Matrix-assisted laser desorption/ionization (MALDI) MS. 🛎Overview: Donndelinger et al methodology reacting multiply charged polyaminoamine (PAMAM) dendrimer cation with a singly charged phosphopeptide anion generated via MALDI. Which then produces dendrimer cation to produce multiply protonated phosphopeptide cations. The product phosphopeptide cations are the fragmented with ECD generating full sequence coverage and enabling phosphate bond localization. 🎯 Summary: Donndelinger et al method exploits the relative ionization efficiency of phosphopeptides in negative ion mode. While also increasing the magnitude and polarity of phosphopeptide charge to versions amendable to ECD fragmentation. Which enables full sequence coverage and phosphate bond localization of MALDI-generated phosphopeptides. Donndelinger et al did compare their method to classical CID fragmentation, when they observed that CID failed generate full sequence coverage and phosphate bond locations remain ambiguous. #massspectrometry #massspec #chemistry #biopharmaceutical #biotech #pharmaceutical #processdevelopment #processmonitoring #mabs #glycobiology #biotechnology #glycotechnology #glycan #medicalsciences #medicalcommunications #medicaldevices #analytical #biopharma https://lnkd.in/eSesR4-b
Sequencing of Phosphopeptides Using a Sequential Charge Inversion Ion/Ion Reaction and Electron Capture Dissociation Workflow
pubs.acs.org
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📄 New #ApplicationNote is OUT 📄 👉 Targeted nucleic acid detection for subsequent sequencing or quantification enables many microbial analysis applications. Nucleic acid detection on a single-cell level offers an unprecedented resolution and insight into the diversity of complex microbial communities if performed in high throughput. Cell isolation into semi-permeable capsules (SPCs) provides a unique opportunity to perform multi-step compartmentalized biochemical reactions. Why SPCs are useful for microbial genomics? 🔘 Isolation of individual cells to retain the linkage between microbial genomes and any additional DNA; 🔘 Analysis of thousands of cells in parallel; 🔘 Compatible with harsh chemical or enzymatic lysis conditions with no trade-offs in terms of the performance of downstream biochemical assays. 🔗 Explore the intricacies of microbial target amplification in #SPCs through our latest application note on our Resource Downloads section: https://lnkd.in/er3bSifq 🔗 Visit our 🟣 #Flux page to get acquainted with your new SPC generation platform: https://atrandi.com/flux 🏷️ #Atrandi #AtrandiBiosciences #Sequencing #Biosciences
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PhD proposal: Development of new bioconjugation reactions applied to nucleic acids
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