"Testing and treating on the basis of gut instinct is one thing, but triaging based on a test is another." Join alejandro zuretti at ADLM 2024 for a roundtable on the MeMed BV test, which quickly differentiates between bacterial and viral infections. He will explain how this technology enhances patient care, reduces unnecessary antibiotic use, and streamlines workflows. Dr. Zuretti will share insights on the test's functionality, cost, and implementation. Learn firsthand how MeMed BV offers cost savings and improves patient experiences by reducing length of stay, increasing treatment satisfaction, and lowering morbidity and mortality, especially for children and the elderly. #HealthcareInnovation #MeMedBV #ADLM2024 #ClinicalExcellence #RapidDiagnostics https://lnkd.in/gTPaNqAW
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According to the World Health Organisation (WHO), there are 11 million sepsis-related deaths every year. Long turnaround times have also severely limited the role of diagnostics leading to both damaging overtreatment and deadly undertreatment when antimicrobial resistant (#AMR) organisms are involved. Today, we are proud to announce a collaboration with Day Zero Diagnostics to develop an end-to-end solution for the same-day diagnosis, and AMR profiling, of bloodstream infections — a leading cause of sepsis. Read more: https://lnkd.in/eQ39fGYQ
Oxford Nanopore and Day Zero Diagnostics Partner to Develop a New Class of Bloodstream Infection Diagnostics
nanoporetech.com
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ASCP Daily Diagnosis 11/29 CST Clinicians and microbiologists who care for patients with diabetic foot infections may be able to decrease the use of mycobacterial cultures and health care costs because these infections are uncommon. Clinicians and microbiologists who care for patients with diabetic foot infections can use these data to implement diagnostic stewardship practices to limit the use of mycobacterial cultures, decrease health care costs, and limit potential patient harm from unnecessary antibiotic exposure. https://lnkd.in/gBsAaZ3w
Mycobacterial infections rare among people with diabetic foot infections
healio.com
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Did you know that between 50% and 60% of women will experience at least one urinary tract infection in their lifetime? And up to half of the bacteria that cause the infections are resistant to at least one antibiotic But, now a test that can identify how to treat a UTI in 45mins has now been selected and its been awarded a £8m prize The winning Sysmex Astrego AB PA-100 AST system is based on technology from Uppsala University in Sweden. A 400-microlitre sample of urine is placed on a phone-sized cartridge and then into a shoebox-sized analyser unit. It can spot bacterial infection within 15 minutes, and identify the antibiotic to treat it within 45 minutes. The test costs about £25 for one cartridge in the private sector, but industry experts say public-sector adoption and high-volume production could see that drop. However, if it became cheap enough for public health facilities or pharmacies, there’s no reason why it couldn’t be effective and really helpful #diagnostics #UTI #pointofcare
Rapid UTI test that cuts detection time to 45 minutes awarded Longitude prize
theguardian.com
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The millions of people impacted by the chronic aftereffects of COVID-19 following infection with SARS-CoV-2 present a significant public health challenge. A recent study in the Annals of Internal Medicine examined whether current tests were adequate to identify post-acute sequelae of SARS-CoV-2 (PASC). PASC, or long COVID, encompasses a broad range of symptoms that can significantly impact quality of life. Depending on the specific manifestations, the symptoms can vary from moderate to severe. Despite its widespread effects, no validated biomarkers exist for this condition. #LongCOVID #COVID19Research #Biomarkers #HealthcareInnovation #ClinicalResearch #PublicHealth #MedicalScience #LabTesting #PandemicResearch #InfectiousDiseases #HealthcareChallenges #ScienceInHealthcare #PatientOutcomes #ResearchUpdates #HealthScience https://lnkd.in/dCW_3G4M
Study finds no clinically useful biomarkers for long COVID in routine lab tests
news-medical.net
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📢The Citest Diagnostics Inc. #Candidaalbicans Rapid Test is a cutting-edge diagnostic tool specifically designed to detect Candida albicans antigens from vaginal swabs. Candida albicans is a #fungus that can cause various infections, including vaginal yeast infections. This rapid test offers significant advantages in diagnosing Candida infections. It provides a quick and accurate assessment of Candida albicans antigens, allowing #healthcare professionals to promptly diagnose and initiate appropriate treatment for patients. The test's high sensitivity and specificity ensure reliable results, enhancing the accuracy of Candida infection diagnosis. With its user-friendly design and efficient workflow, the Candida albicans Rapid Test streamlines the diagnostic process, leading to improved patient care and timely interventions.🛡️ 🔎Learn more: https://lnkd.in/gTvxPt-D
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A synbiotic preparation (SIM01) for post-acute #COVID-19 syndrome in Hong Kong (RECOVERY): a randomised, double-blind, placebo-controlled trial « Treatment with SIM01 alleviates multiple symptoms of PACS. Our findings have implications on the management of PACS through gut #microbiome modulation. Further studies are warranted to explore the beneficial effects of SIM01 in other chronic or post-infection conditions » https://lnkd.in/eMr7FW6D
A synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong (RECOVERY): a randomised, double-blind, placebo-controlled trial
thelancet.com
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Please see my new article in Contagion_Live describing 2 new papers published in OFID on topics in Skin/ Soft Tissue Infections. These papers should help guide primary care/IM/ Hospitalist and Infectious Disease Consultant interactions regarding the care of patients with lower limb cellulitis and infected diabetic foot ulcers (DFU) #contagionlive #infectiousdiseases #diabeticfootulcer #cellulitis #empiricantibiotics https://lnkd.in/dYBnvgZ4
Two Pragmatic Approaches to Skin and Soft Tissue Infections
contagionlive.com
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🔬🦠 The AIM Viral project implements a single test for diagnosing #COVID19 and other respiratory illnesses in clinics and emergency departments. It will assess how multi-pathogen testing impacts patient care and antibiotic use. https://lnkd.in/eXcjriH6
Assessing the Implementation of Point-of-Care Multiplex Viral Testing in Primary Care (AIM-Viral) » Upstream Lab
https://upstreamlab.org
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Today is the first day of World AMR Awareness Week. Antimicrobial Resistance (AMR) occurs when bacteria, viruses, fungi and parasites no longer respond to antimicrobial agents. As a result of drug resistance, antibiotics and other antimicrobial agents become ineffective and infections become difficult or impossible to treat, increasing the risk of disease spread, severe illness and death. The World AMR Awareness Week is a global campaign to raise awareness and understanding of AMR. On the hub below we’ve selected ten resources related to antimicrobial resistance. Shared with us by hub members and patient safety advocates, they provide valuable insights and practical guidance about AMR: https://lnkd.in/ef_JTad4 #WorldAMRAwarenessWeek #AantimicrobialResistance #AMR #patientsafety #medicationsafety #medicinessafety
Top picks: 10 key resources on antimicrobial resistance
pslhub.org
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Chief Science Officer & Co-founder, Board Certified Infectious Disease and Internal Medicine Physician, Epidemiology, Clinical Informatics, IDSA member, Medical Writer, Children's Book Author, and Musician
Rapid diagnostic tests for infectious diseases, such as PCR, are still not widely available and are not universally accepted as part of sepsis protocols. Healthcare providers and institutions have been slow to adopt these technologies. However, studies have demonstrated that the use of these tools coupled with antimicrobial stewardship may lead to a survival benefit! #antimicrobialstewardship #antibioticresistance #publichealth #sepsis #prescriberesponsibly https://lnkd.in/efasa_nK
Rapid diagnostic tests and antimicrobial stewardship programs for the management of bloodstream infection: What is their relative contribution to improving clinical outcomes? A systematic review and network meta-analysis
academic.oup.com
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Independent Consultant
1moMore and more evidence is indicating that the life-threatening response to infection is due to persistently elevated NETosis. Simultaneous co-infections with both viruses and bacteria commonly occur as this article points out https://theconversation.com/when-covid-19-or-flu-viruses-kill-they-often-have-an-accomplice-bacterial-infections-187056 and both types of pathogens in addition to fungi can trigger excessive NET induction, formation, and result in a lack of NET clearance. Therefore, I would also like to see NET measurement standardized and clinically approved. An increase in circulating NETs positively correlates with the risk of developing DIC and NETs very likely need to be therapeutically targeted in addition to the use of appropriate antimicrobials.