Michelle Routhenstein, MS, RD, CDCES, CDN’s Post

Dietary patterns may influence lung function growth beyond the possible effects of individual foods and nutrients. In our recent paper (https://rdcu.be/c7OvF), we have shown that children with a health-conscious diet at mid-childhood had higher lung function in adolescence, whereas those with a diet high in processed foods had lower lung function. This could not be explained by vitamins, antioxidants, or fibres, suggesting the importance of a ‘whole diet’ approach. These associations partly depended on genetic makeup; for example, children with a higher level of an anti-inflammatory protein in the lung (CC16) may benefit more from a healthy diet and be more vulnerable to a poor diet at the same time. #diet #lung_function #childhealth #genes #gene_diet_interaction #growth #ALSPAC #WIPH_QMUL Rosetrees

🧠 The Power of Ketogenic Diets: Ketogenic diets are emerging as a game-changer in managing various neurological disorders in adults. From epilepsy to Alzheimer's disease, migraine, amyotrophic lateral sclerosis (ALS), and malignant glioma, the evidence is compelling. Studies reveal that reducing carbohydrate intake and increasing fat consumption can positively impact seizure control in refractory epilepsy patients and enhance cognitive function in those battling Alzheimer's. The therapeutic efficacy of ketogenic diets stems from the production of ketone bodies, serving as an alternative energy source for the brain. This metabolic shift reduces neuronal excitability, modulates neurotransmission, and curbs inflammation in the central nervous system, ultimately alleviating symptoms across neurological conditions. Despite their promising therapeutic benefits, ketogenic therapies in adults may come with some adverse effects. Commonly discussed in studies are weight loss, gastrointestinal disturbances, and temporary lipid level fluctuations. While weight loss may be desirable for some, monitoring caloric intake becomes crucial for those aiming to maintain or gain weight. Gastrointestinal issues like constipation, diarrhea, and nausea are frequently reported among adults on ketogenic diets. Strategies such as smaller, frequent meals, increased fibre and fluid intake, and gradual introduction of medium-chain triglycerides (MCTs) can mitigate these side effects. Additionally, guidance from a specialized Dietitian is indispensable to address these adverse effects and ensure treatment safety and efficacy. Another discussed adverse effect is the temporary rise in blood lipid levels, often a response to increased fat consumption in the ketogenic diet. Though usually transient and non-detrimental, regular lipid level monitoring is essential, adjusting the diet as needed to minimize this effect. In summary, ketogenic diets prove to be an effective therapeutic option for managing various neurological disorders in adults, operating through mechanisms like ketone body production and metabolic modulation. Despite their potential benefits, awareness of potential adverse effects is crucial, alongside professional healthcare guidance to ensure treatment safety and efficacy. Let's unlock neurological health together! 💪 #KetogenicTherapy #NeuroHealth #WellnessJourney #BrainHealth #Nutrition #Dietitian ➡ Full article: McDonald TJW, Cervenka MC. Ketogenic Diets for Adult Neurological Disorders. The American Society for Experimental NeuroTherapeutics, Inc. Published online September 17, 2018.

“Let food be thy medicine, and let medicine be thy food" Hippocrates This quote could not be more relevant than it is today. Many of our current health issues, including the overburdening of our health systems can be alleviated with simple dietary changes. Reading this review by Dr's Vijay and Valdes in the European Journal of Clinical Nutrition really highlights the role that our Gut microbiome plays in promoting many of our current chronic health conditions that we are seeing today. This is closely linked to out Gut barrier integrity which has been shown to be critical in maintaining healthy homeostasis. The review is open access and I invite you to check this out in the link below: https://lnkd.in/eVbusuuV

High Fat Diet 32 (HFD32): A Super-High-Fat Pelleted Diet for Diabetes and Obesity Research in Mice and Rats   Introduction: CLEA Japan introduces HFD32, a revolutionary high-fat diet (32% fat content, 60% energy from fat) for in vivo research on diabetes and obesity. Unlike traditional powdered high-fat diets, HFD32 comes in convenient pellets, enhancing ease of use and animal acceptance.   Features: ・Super-high fat content: Induces obesity and glucose intolerance effectively. ・Pellet form: Improves handling and reduces dust exposure compared to powdered diets. ・Proven efficacy: Triggers significant weight gain, impaired glucose tolerance, and increased visceral fat in mice studies. ・Versatile research tool: Suitable for diabetes and obesity studies, as well as investigating the effects of sugar, light cycles, and sterilization on metabolic syndrome.   Availability and Storage: ・Pre-packaged (3 kg, 6 x 500 g bags) and readily available in both irradiated and non-irradiated variants. ・Frozen storage mandatory; defrosts quickly for feeding (1h at -20°C, 3h at -80°C).   Additional Information: ・HFD32 comes with detailed reference data on mouse studies, ingredients, fatty acid composition, and test results. ・A comprehensive FAQ section addresses common questions regarding delivery, custom diets, storage, and compatibility with other research protocols.   In conclusion, CLEA Japan's HFD32 presents a reliable and convenient solution for inducing diabetes and obesity models in mice and rats, contributing to advancements in metabolic research. For more detailed information, please click here 👉 https://lnkd.in/gz4dJXt3 #experimentalanimal #dietinducedobesity #diabetes #cleajapan

Gut Microbiota and Obesity: The Chicken or the Egg? Although the link between gut microbiota and obesity is increasingly reported, the pathophysiological mechanisms and clinical outcomes are still under debate. This overview of human and animal data addresses several pathophysiologic mechanisms, dietary habits, exercise and probiotic and symbiotic supplementation in the fields of gut microbiota and obesity. Overall, obesity impairs gut microbiota composition due to factors that may be linked to the onset of the disease, such as excessive consumption of high-energy foods, sugars and fats, as well as a low fiber intake and physical inactivity. Conversely, low-energy diets, physical exercise, and probiotic and prebiotic supplementations can enhance gut microbiota in patients with obesity, in addition to improving cardiometabolic markers. As for perspectives, further research is warranted to ascertain proper dietary manipulation, physical exercise protocols and dosing regimens of probiotics. Regarding the latter, the effects on indicators of obesity are clinically modest, and hence skepticism must be exercised. Read the rest of the article here https://buff.ly/3GmGrwj 👈 Visit our website https://buff.ly/3N1bcK8 😄 Watch The Impact of Preventable Disease on Enterprises. https://buff.ly/43DgkdQ 👈 Pre-register here: https://buff.ly/3NzDfAZ 👈 Follow Us on LinkedIn https://buff.ly/3Jy2Wk7 👈 #ImmuneSystem #GutMicrobiota #Thier #HealthisWealth #ImmuneHealth #StayHealthy #GutHealthBenefits

#aging #nutrition #longevity #health https://lnkd.in/gXH-kSYn Abstract Ageing is a multifactorial process associated with reduced function and increased risk of morbidity and mortality. Recently, nine cellular and #molecular #hallmarks of #ageing have been identified, which characterise the ageing process, and collectively, may be key determinants of the ageing trajectory. These include genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion and altered intercellular communication. Healthier dietary patterns reduce the risk of age-related diseases and increase longevity and may influence positively one or more of these hallmarks. The Mediterranean dietary pattern (MedDiet) is a plant-based eating pattern that was typical of countries such as Greece, Spain, and Italy pre-globalisation of the food system and which is associated with better health during ageing. Here we review the potential effects of a MedDiet on each of the nine hallmarks of ageing, and provide evidence that the MedDiet as a whole, or individual elements of this dietary pattern, may influence each hallmark positively—effects which may contribute to the beneficial effects of this dietary pattern on age-related disease risk and longevity. We also highlight potential avenues for future research.

🧠 Understanding the Role of Diet and Nutrition in Parkinson's Disease Management 🧠🌿 Explore how dietary choices can impact Parkinson's disease. Learn key strategies to support health, alleviate symptoms, and enhance quality of life. Join us on this journey to better living through nutrition! 🌟 Read Here 👉 https://shorturl.at/V4dz4 Call 📞 - +91 91040 80055 #ParkinsonsAwareness #NutritionMatters #HealthyLiving #WellnessJourney #Drchiragsolanki #Neurosurgeon

I fell down the personalized nutrition and fxmed rabbit hole ~15 years ago... ✨️I remember talking to colleagues way back when about detoxification and being told that was junk science. ✨️I was at medical conference in 2016 and was basically laughed at for mentioning the microbiome in a conversation about antibiotic stewardship and its implicationsin chronic disease epidemic. ✨️I've had heated debates about SIBO, non-celiac gluten sensitivity, and glyphosate reactivity with colleagues who insisted they didn't exist. ✨️I'll never forget the absolute AWKWARD silence I was met with when I once stated my case for reversing diabetes and autoimmune remission through lifestyle and diet at medical meeting. The good news is, the science in this field is evolving at an incredible pace... And the intrest in fxmed and nutrition is catching up. During these past 15 years I've been in this space, we've seen some of these concepts become practically mainstream: ✔️ The impact of the microbiome on disease and health risk ✔️ Lifestyle medicine has a proven risk reduction of 80% and 90% for CVD and diabetes respectively* ✔️ SIBO and dysbiosis are well-established contributors to IBS and the mind-gut connection is generally well-known ✔️ Heavy metal, PCBs, glyphosate and other toxicant exposures have been linked to neurological, metabolic, and immune disease We still have some ways to go, but it's kinda incredible to see the forward momentum of this evidence-informed movement 🙌🏽 👉🏽 What do you think had been the biggest mainstream "aha" that used to be misunderstood or underestimated? Let's keep the conversation going in the comment's below 👇🏽! I'll leave these here 😉: PMID: 34584224 https://lnkd.in/ebxsJURh PMID: 31315227 https://lnkd.in/e-duw7B9 PMID: 28274108 https://lnkd.in/e7CsXpc7 *PMID: 30800027 https://lnkd.in/eWC73wJq PMID: 33281521 https://lnkd.in/eXRhBmDv PMID: 35389853 https://lnkd.in/eNbFSgFu PMID: 35215417 https://lnkd.in/epmQucPV PMID: 36911452 https://lnkd.in/eTHAZTiJ PMID: 36430748 https://lnkd.in/eTTAVB2e #lifestylemedicine #personalizednutrition #functionalmedicine

What is the Healthy Gut Microbiota Composition? A Changing Ecosystem across Age, Environment, Diet, and Disease : #gutmicrobiota, #diversity, #health, #diet, #nutrition, #age, #milkshakefeeding, #necrotizing #enterocolitis, #weaning, #enterotypes, #irritablebowelsyndrome, #inflammation #bowelcancer, #celiacdiseasedisease, #colorectalcancer , #obesity, #type1diabetes #type2diabetes, #Alzheimer’sdisease, #Parkinson’s, #hepaticencephalopathy, #autismspectrumdisorder, #personalizedmedicine

A recent study of n=8,010 adults without HTN, using data from the National Health and Nutrition Examination Survey found higher flavonoid intake was associated with prevalence of hypertension. Noticeably, two flavonoids: anthocyanin and flavan-3-ols were found to be negatively associated with prevalence of hypertension (38% and 21% reduction in risk of hypertension respectively when comparing higher intake to the lowest intake). As potent antioxidants, flavonoids were believed to protect the vascular system, reduce inflammation, and oxidative stress in the body. They are most abundantly found in fruits and vegetables like berries. Balancing our diet with adequate and a variety of flavonoids-rich produce can help maximize their cardio-protective potentials. #flavonoids #anthocyanin #flavan3ols #hypertension. Read More Here: https://lnkd.in/e6gr-gez