Miltenyi Biotec’s Post

Have you ever thought about how your cells feel after sorting? 🤔 This article touches "the impact of shear forces, osmotic forces, laser excitation, and electrical charges on cell health during traditional FACS" in stem cell research. https://lnkd.in/e8--8Xnv Need hard scientific data about the impact on cells? 😱 This recent publication from AstraZeneca makes a strong case why sorting with the microfluidic sorter MACSQuant Tyto has a minimum impact on the metabolism of cells and is less disruptive compared to classical droplet-based sorting. https://lnkd.in/eEi8wvnT Want to know why the Tyto is such a gentleman? 😇 It´s all about pressure, decompression, charges and shear forces. Get more insights here: https://lnkd.in/e-zautJa #astrazeneca #metabolomics #cellandgenetherapy #sterile #infectiousdisease #personalizedmedicine #flowcytometry #facs #microfluidic

🔬🌿 Unlocking the Power of Stem Cells: A Journey Through Potency and Promise 🧬 In our latest blog post, we dive deep into the world of stem cells, exploring the different types and their potency. From the pluripotent embryonic stem cells (ESCs) to the multipotent adult stem cells (ASCs) and the groundbreaking induced pluripotent stem cells (iPSCs), we unravel the unique properties and potential applications of each type. 🔍 We also shine a spotlight on mesenchymal stem cells (MSCs), a promising subtype of ASCs that have garnered significant attention in regenerative medicine. 💪 Companies like 23 Century Lifecord in Malaysia are at the forefront of harnessing the power of MSCs derived from umbilical cord blood to develop innovative treatments for various conditions. 🇲🇾 But which stem cell type holds the most promise? 🤔 We compare the potency and characteristics of ESCs, ASCs, and iPSCs, discussing the advantages and limitations of each. While ESCs offer the broadest differentiation potential, ethical concerns and the risk of teratoma formation have limited their clinical applications. ASCs, particularly MSCs, provide a more accessible and ethically acceptable option, with the ability to target specific tissues and exert immunomodulatory effects. iPSCs bridge the gap between ESCs and ASCs, enabling patient-specific therapies and disease modeling, but their clinical translation is still in the early stages. The future of stem cell-based therapies is bright, and by staying informed about the latest developments and supporting ongoing research efforts, we can contribute to the advancement of these life-changing technologies. 🌟 Read our blog post now to uncover the fascinating world of stem cells and learn how companies like 23 Century Lifecord are pushing the boundaries of regenerative medicine! 🔗 Link in the comments below. 👇 https://lnkd.in/gSw2ACG2 #StemCells #RegenerativeMedicine #CellTherapy #MedicalResearch #23CenturyLifecord #Biotechnology #Science #Innovation

Are you up to speed on the ongoing debate reshaping our approach to stem cell research, emphasising a more ethically considerate path? Our latest update delves into induced Pluripotent Stem Cells (iPSCs). Unlike embryonic stem cells, iPSCs present a less contentious alternative, steering clear of the ethical and moral debates. iPSC technology is changing regenerative medicine, enabling researchers to bypass the ethical concerns of using embryos. It's a fundamental shift in the scientific community's approach to exploring potential treatments and therapies. Stay informed with our iPSC-dedicated series of articles on how these induced Pluripotent Stem Cells could impact future medical breakthroughs. It's an exciting time for #CGT, and we're here to keep you updated, so don't forget to follow us! Do you have questions? Start a conversation with our BDs Tristan Pritchard-Meaker and Sophia Kolbe! #ipsc #stemcellresearch #celltherapymanufacturing

🗣 Exciting news for our collaborators and #stemcell scientists working with FGF-2… We have rebranded our star product: The Thermostable FGF-2, formerly known as STAB, now is named...    👇👇👇   *FGF-2 TOP® (Thermostability Optimized) As a crucial factor to obtain high quality cultures during #stemcell expansion (#pluripotent and #mesenchymal) and differentiation (#neural, #myogenic, #endothelial), the heat stable version of FGF-2 with extended half-life (>7days) at 37ºC is becoming the new gold-standard for the field 🧪 However, to date very few options are available on the market, and most of them come with inconsistent quality attributes, or are offered at very high costs - thus impeding the progress of advanced stem cell science 🔬 Since we got the license for the patented engineered sequence of the #ThermostableFGF2 from Enantis, at Core Biogenesis we have proven a solid track record for enabling scientists to optimize their stem cell culture protocols, while offering the only available product at lower price - 50-70% less than market average, thanks to our sustainable biomanufacturing platform 🌱 Now, is the perfect time to give our product the credit it deserves, and stand-out from the rest! Choosing TOP (Thermostability Optimized) was an easy decision thanks to the 👉 ▪️ TOP Performance 🥇 ▪️ TOP Results 🧫 ▪️ TOP Users 👩🔬👨🔬 *All the product specifications and formats are preserved as before, with the only difference of the new name 🔝 Join us in our mission to improve current lab protocols and democratise the access to advanced stem cell science 🙌 If you are interested in FGF-2 TOP® or want to learn more, contact us: https://lnkd.in/eJ3DcmiW #stemcellresearch #pluripotentstemcells #thermostablefgf2 #productrebranding

Journal of Stem Cell Research Stem cell research stands at the forefront of medical science, offering the potential to revolutionize the way we understand and treat a wide array of diseases and injuries. By investigating the unique properties and capabilities of stem cells, researchers aim to unlock new therapies that can regenerate damaged tissues, treat incurable diseases, and improve patient outcomes. Stem cells are unique cells with the ability to develop into many different cell types in the body during early life and growth. They serve as a repair system, replenishing adult tissues. Read our recent published work at: https://lnkd.in/gB5FdYzX Submit your work at: [email protected] For anymore queries whatsapp at: +1 (438) 699-5365 #stemcell #celltherapy #StemCellInnovation #CallForPapers #ResearchSubmission #BiotechResearch #InnovativeTherapies #StemCellScience #RegenerativeMedicine #StemCellResearch #postdoc #researcher

15th Annual Stem Cell Society Singapore (SCSS) Symposium The 15th Annual Stem Cell Society Singapore (SCSS) Symposium will be held in person from 29th November to 1st December 2023, at the Auditorium, L2 Matrix Building, Biopolis. SCSS's annual symposium is the most important stem cell event in town, bringing together local and international scientists, healthcare professionals, industry players, and anyone interested in or supporting stem cell research and cell therapy. The 2023 Symposium will focus on "Stem Cell Innovations in Research and Healthcare," and we are especially excited and proud to present as keynote speakers Prof Shinya Yamanaka, Kyoto University, and Prof Suchun Zhang, Duke-NUS. We are enthusiastic to share stimulating science in the field of stem cells and cell therapy with you once more. Please see our website at  https://lnkd.in/g3D8Fezh for more details. The deadline for early registration and abstract submission is October 15, 2023. #stemcell #celltherapy #biotech #research #singapore #researchanddevelopment #healthcare #innovation #cellculture

Glaucoma is a leading cause of vision loss, which can’t be reversed due to the loss of cells responsible for vision. Most efforts with stem cell transplants have not been successful because the cells never arrive at their designated destination. Now, a research team led by Petr Baranov, MD, PhD, assistant scientist at the Schepens Eye Institute of Mass Eye and Ear, has found a promising method for repopulating these cells by changing the microenvironment in the eye, enabling stem cells to migrate and survive in the retina in preclinical models. Learn about the study, which was recently published in PNAS: http://spklr.io/6041mLLU.

Stem cells can self-renew and differentiate into a vast array of specialized cell types and are therefore of high value as a research model for studying development and disease. This eBook provides a comprehensive collection of articles and interviews about the unique challenges scientists face with stem cell workflows and the benefits of automated solutions for stem cell imaging, isolation, and retrieval. Read to learn about: ☑️ The challenges of stem cell research ☑️ The benefits of single-cell isolation versus cell population studies ☑️ Fully automated image-based single-cell and colony picking for stem cells ☑️ Precise transfer of stem cell clones and colonies ☑️ Induced pluripotent stem cell (iPSC) culture, maintenance, and characterization Download now: https://ow.ly/JooG50QqXya #stemcells #labautomation #stemcellworkflows #lifescienceresearch #cellcelector

🌟 Inner Ear Organoids: Exciting in vitro model development showcased at the global Stem Cell Event last week in Hambourg 🌟 Last week at ISSCR, Sylvie Pucheu, Léa Jaillot, Ezeddine Harmouch and Azel Z. from LBN Montpellier University presented their recent work on an Efficient Embryoid-based Method to Improve Generation of Otic Vesicles from Human Induced Pluripotent Stem Cells. This 3D in vitro strategy aims to better understand the mechanisms of human otic development and test novel regenerative therapies to combat hearing loss and balance impairments. 🔬 Innovation: The research team adapted a protocol to improve embryoid body-based otic induction from hiPSCs, preserving the integrity and viability of cells forming the otic embryoid bodies (OEBs) and otic vesicle-like structures. Using a Sox2-GFP reporter hiPSC line, we tracked the progression from pluripotency to otic progenitors, showing robust otic induction and improved vesicle generation between days 11-60 of cell cultures. This is a great milestone for the OrgaEar project directed by Professor Azel Zine, that we conduct in collaboration with the University of Montpellier and the support of SATT AxLR. #Organoids #Innovation #StemCells #InVitroModels #TherapiesDevelopment #InnerEarPathologies #ISSCR2024 #HearingResearch #RegenerativeMedicine