Please join us: Friday, June 21 at 11 AM PT for an important conversation: A Turning Point in ALS Trials https://lnkd.in/gwxGEJVv June 21 marks the northern hemisphere’s summer solstice – a turning point – and on this day, the ALS/MND community undertakes activities to express our hope for a turning point in the search for cause, treatment, and cure of ALS/MND. To drive a turnaround in trials for ALS and other neurological diseases, we at Modality advocate for new tools that increase understanding of the course of disease and response to treatment. Together with partners such as MGH, Everything ALS, and recently, Verge Genomics, we're building the most comprehensive audio/visual dataset of people living with ALS. Please join us: Friday, June 21 at 11 AM PT for a 45-minute live webinar in which we will share highlights from our recent publications and discuss advancements in digital endpoints and the potential to accelerate clinical research with special guest Karl Kieburtz, MD, MPH, Co-Founder and Chair of Clintrex, and principal investigator for numerous multi-center trials in neurology. Please register here: A Turning Point in ALS Trials (you'll be prompted to "Sign in with Zoom" or "verify with email"). https://lnkd.in/gwxGEJVv #ALS #clinicaltrials
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🔍 Don't Miss Our Upcoming Webinar: "Mistakes in Diagnosis" Join us on November 13, at 12:00 CET for a deep dive into the analysis of diagnostic mistakes, their causes, consequences, and solutions Hurry to secure one of the last 30 spots! This is an opportunity you don't want to miss. 🕛 🔬 Topics include: 1. Lack of continuity amongst hospitals 2. Lack of time during patient visits 3. Lack of trust between multi-clinical or multinational clinics and labs 🎤 Featuring: Elina Sharifullina - Global Scientific Chief Officer at Ornament Health - Doctor of Philosophy (PhD) in Neurobiology and Neurosciences - Doctor of Medicine (MD) in Endocrinology - 9 years of industry experience This is a must-attend event for medical professionals who often struggle with limited time and information during initial diagnoses. Learn how biomarkers and their dynamics can revolutionize your diagnostic process. Stay tuned for more webinars, including sessions on understanding biomarkers, even for professions where it might not seem necessary. We're committed to elevating healthcare knowledge. 🚀 👉 Register Now: https://lnkd.in/d3MRgnn5 #OrnamentApp #healthrevolution
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🔬 Research 101; Early Bird discount!!!!! The Charaka Project is now accepting applications for its Research Module, Research 101. We have had a phenomenal time in the last cycle and we have returned with a freshened-up module. Please, hurry and avail a 30% early-bird discount until the 28th of March. We'll be taking the following topics for our small working groups. 1️⃣ Impact of point-of-care ultrasound (POCUS) on early diagnosis and clinical decision-making in patients with suspected acute heart failure in the emergency department. 2️⃣ Comparative effectiveness and safety of minimally invasive surgical techniques versus traditional laparoscopic approaches for the management of benign ovarian cysts in women of reproductive age. 3️⃣ The evolving role of artificial intelligence (AI) in the diagnosis and management of depression: A narrative review of the current landscape and future directions. 4️⃣ The intersection of chronic stress, inflammation, and cardiovascular disease risk: A narrative review exploring potential therapeutic targets. 🔗 You can find the registration link here: https://lnkd.in/evtt7Ka9 🏷 Tag interested folks and comment down below to seek availability information. 📒 the topics can be changed for the better, as per the development of the protocol. #researchmd #systematicreview #academicguide #literaturesearch #researchcommunity #guidance #researchmethods #srma #USMLE #opportunity #research #IMG
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Welcome to the OM1 Parkinson’s Disease Dataset! With no currently known cure and no interventions that meaningfully reduce the progression of PD, it is tremendously important to find potential patient populations as early as possible since these medications are most effective in the early stages. With the OM1, Inc. Research-Grade, Parkinson’s Disease, Real-World Data (RWD), companies can access longitudinal, multi-source, curated datasets, offering rapid access to deep clinical data, insights, and outcomes. OM1 RWD offers; ✔ 803,000+ total Parkinson’s Disease patients in the OM1 Real-World Data Cloud. ✔6,200+ Parkinson’s disease patients with neurologist notes ✔5,308+ Parkinson’s disease patients with deep clinical data With our specialized RWD for PD, customers can leverage data and OM1 expertise to access; ✔Advanced therapies and comorbidities ✔Demographically & geographically diverse population ✔Social Determinants of Health (SDoH) data ✔Clinical notes for additional extraction and curation Meet our expert, Carl D. Marci, M.D. our Chief Clinical Officer and Managing Director of Mental Health and Neuroscience at OM1. Let’s connect to learn more about how OM1 can support necessary insights around current research studies. Check out the links below for more information; 📍Book a meeting: https://lnkd.in/eJcKBAJK 📍Neuro eBook: https://lnkd.in/eKhdanKx 📍PD Smart Link : https://lnkd.in/eF4adVxY #parkinsonsdisease #pd #neuroscience #patientjourneys
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The first comment has the link 🔗 to the full text article.
#FridayFeeling read a blog about the recent publication of the #eHealthH2H randomised control trial (#RCT) protocol. #digitalhealth #nurseresearch #heartfailure #colorectalcancer #remotemonitor University of Stavanger, Marianne Storm, Ingvild Morken, Dr Rosalynn Austin, Oda Nordfonn, Hege Wathne, Kristin Hjorthaug Urstad, Bjørg Karlsen, Ingvild Dalen, Kari Hanne Gjeilo, Alison Richardson, Glyn Elwyn, Edvin Bru, Jon Arne Søreide, Hartwig Kørner, Rune Mo, Anna Strömberg, Hilde Lurås, and Mia Lunde Husebø https://lnkd.in/eyznYHNr
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President & Founder Care Constitution, LLC & ORintelligence, LLC - Professor at George Washington University - School of Medicine and Health Sciences
A Quantitative Human Factors Study of Neurology Examination with the Aid of AI and Digital Technology: This post addresses the challenge of monitoring patients with neuromuscular conditions, as outlined by the MGnet initiative (https://lnkd.in/gtXYF8c4). We propose a comprehensive digital solution that can automatically compute the MG-Composite score from a standard Zoom call (reference: https://lnkd.in/dqe_PZbn). However, to ensure the validity of this approach, we also need to understand the factors that can influence the reproducibility of the MG-Composite score during a standard clinical examination performed by a certified neurologist. This new manuscript (reference: https://lnkd.in/g6iDkP57) investigates why specialists may often assign different scores to the same patient based on the same telemedicine Zoom call.
Enhancing discovery and treatment for the myasthenia gravis patient community
mgnet.rarediseasesnetwork.org
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Today, I am pleased to highlight a significant achievement by a wonderful member of our research group. In 2021, Hannah Nora Wolf took her first steps into the complex world of biomedical research as part of her master's degree. Recently, she brought her findings to light, opening avenues for potentially groundbreaking developments in the future. 🔬 Research Highlights: In her master's thesis, Hannah Nora Wolf investigated the potential of human antibodies isolated from the blood of NMOSD patients to bind ex vivo to mouse retinas. These antibodies were shown to stimulate gliosis and alter cytokine patterns without affecting complement transcription. These initial results could serve as a stepping stone for innovative studies in this area. 💪 We appreciate every contribution: As we all strive for significant publications, it is critical to recognize the tremendous impact that even a first publication has, especially for young scientists. I remember my first steps in this field being a mixture of excitement and respect. It's important to give publicly funded data a platform, even if it doesn't make a perfect, well-rounded story. Sharing this data with a balance of caution and objective criticism can be productive ground for learning and growth. 🔎 Shared Excellence: This journey was fostered by the collective efforts of the entire amazing ***Experimental Ophthalmology Marburg*** team, complemented by the insights of NMOSD experts in Munich. 💼 A glimpse into the future: Get ready to see more from Hannah Nora Wolf, as her ongoing PhD work already hints at promising discoveries, with a particular focus on endothelial cells. 🎉 Celebratory Notice: Just 11 days after publication, nearly 300 people have already engaged with Hannah's findings. Such outreach would not have been possible if the research had remained in the drawer. Let's celebrate the impact and reach that sharing research can have, and foster a spirit of collaboration and intellectual curiosity in the scientific community. Let's celebrate Hannah's dedication and hard work together, and stay tuned for more groundbreaking updates from her research journey! https://lnkd.in/er3VFSNp #ScientificResearch #Teamwork #MasterThesis #NMOSD
NMOSD IgG Impact Retinal Cells in Murine Retinal Explants
paulylab.de
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If you are interested in recent advances in drug development for #parkinsons #alzheimers , Don't miss this event! To learn more, email [email protected]. #CPath #CPAD #CPP #Parkinsons #datasharing #drugdevelopment #patientvoice #globalhealth #collaboration #neurodegeneration #neuroscience #neurodegenerativediseases
C-Path’s 2023 Neuroscience Program Annual Meeting is set for Thursday, November 30 in Washington D.C. Bringing stakeholders together from both the Critical Path for Alzheimer’s Disease and the Critical Path for Parkinson’s consortia, this meeting will build off the recent advancements in drug development for Parkinson's and Alzheimer's, exploring important opportunities to apply lessons from successes in both therapeutic areas. The key objectives of the meeting are to: 🔑 Examine the state of markers of disease modification across the disease continuum, with an emphasis on early disease stages (and how to optimize their definition), in AD and PD. 🔑 Contextualize clinical meaningfulness across the disease continuum in AD and PD by incorporating the patient voice. 🔑 Prioritize which drug development tools are needed to accelerate development of disease modifying treatments in partnership with industry and drug development experts. To learn more, email [email protected]. Daniel Jorgensen, MD, MPH, MBA Kristen Swingle Klaus Romero Diane Stephenson Sudhir Sivakumaran, Ph.D. #CPath #CPAD #CPP #Parkinsons #Alzheimers #datasharing #drugdevelopment #patientvoice #globalhealth #collaboration
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Mayo Clinic and The MOG Project are united in the mission to improve the lives of individuals with MOGAD. Learn how this strategic alliance is advancing the science behind the devastating neurological illness in this "Eye on Innovation." https://bit.ly/3xEsbxT
Progressive alliance advances science through patient-powered research - Insights
news.mayocliniclabs.com
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C2N applauds the terrific work of CEOi - Global CEO Initiative on Alzheimer's Disease BBM Workgroup and the many experts who contributed their time, resources, and knowledge to develop an impactful guide that will significantly elevate the quality of blood biomarker tests for the benefit of patients dealing with cognitive concerns. We believe the guide highlights the importance of robust, rigorously-studied biomarkers. Indeed, we think these standards will pave the way for faster adoption of high-performing blood tests that will meet the criteria. The expert recommendations are available at Nature Portfolio Reviews Neurology. We appreciate the special recognition from the expert panel for the higher accuracy of Liquid Chromatography with tandem mass spectrometry (LC-MS-MS), and for the high bar the experts set for confirmatory testing. This is the high bar we also set for ourselves when we launched our PrecivityAD2 test in the U.S. last summer and more recently in Brazil and Australia via lab partners, Grupo Fleury and Healius Limited, respectively. All patients deserve the highest quality care. https://lnkd.in/eHTqqvNq. https://lnkd.in/edUWv9ri https://lnkd.in/eqefnnAu #Alzheimers #Nature # #liquidbiopsy #CEOi #bloodbiomarkers #research #precisionmedicine
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Friedreich ataxia (FA) is an inherited, multisystem neurodegenerative disease that results in profound changes to speech, swallowing, balance, walking, cardiac health and upper limb function. TRACK-FA is an imaging study focussed on building a better understanding of the impact FA has on the brain and its relationship to clinical features of the disease. The team of investigators working across 7 sites in the USA (University of Florida, University of Minnesota & Children's Hospital of Philadelphia), Brazil (Universidade Estadual de Campinas), Australia (Monash University), Germany (RWTH Aachen University) and Canada (McGill University) scan patients every 12 months over 3 years using sophisticated brain imaging techniques. Patients are also completing a comprehensive battery of clinical assessments to establish the relationship between the brain and behaviour. Redenlab are supporting the study through the inclusion of a digital speech protocol. Data will inform future protocol design in ataxia and strengthen links between meaningful clinical outcomes and underlying neuropathology. For more information on the protocol and the team at Monash University leading the study, visit https://lnkd.in/gUgKThPc To learn more about Redenlab and our work, visit https://redenlab.com/ #friedreichataxia #neurodegenerativedisease #clinicalstudy #research #speech
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