Molecular Assemblies, Inc.’s Post

Here are 13 new technologies that you can learn about at #SynBioBeta2024 this year: https://lnkd.in/gJyKRH4U #GenerativeAI for #bio (e.g. Absci) Enzymatic #DNA Synthesis (e.g. Molecular Assemblies, Inc.) #Cellfree synthetic biology (e.g. Stemloop, Inc.) DNA #DataStorage (e.g. Twist Bioscience) Cellular Reprogramming (e.g. bit.bio) Precision #Fermentation (e.g. TurtleTree) Biological #carboncapture (e.g. Novonesis) #Bioremediation (e.g. Allonnia) #PersonalizedMedicine (e.g. Centivax) #Biomaterials (e.g. Checkerspot) #Biomanufacturing and scale up (e.g. Pow.bio) #3DBioPrinting (e.g. United Therapeutics Corporation) High Throughput Fermentation (e.g. TJX Bioengineering)

Ignorance is bliss, but not in the case of molecular biology Nucleic acid contaminants can affect downstream applications in two main ways: - They artificially inflate the reported concentration, and you therefore use less template than intended - They inhibit enzymes, preventing reactions from proceeding as expected The Thermo Scientific™ Acclaro™ Sample Intelligence technology in the NanoDrop™ One, OneC and Eight models, identifies and corrects for common contaminants in your samples, giving you a better understanding of sample quality. Save time, money and precious samples, by using NanoDrop™ as part of your sample preparation workflow Contact Labtech to arrange a demonstration, or to learn more, before you have to endure the pain of troubleshooting failed assays https://lnkd.in/eG4Kw5zx https://lnkd.in/ec22UwUD https://lnkd.in/eQv5QMYU

“STOP CLONING!” The main message from the CEOs at the top DNA synthesis companies like Twist Bioscience, Molecular Assemblies, Inc. , ELEGEN , DNA Script , Ribbon Biolabs: Your valuable scientific resources should be focused on value-add research. They shouldn’t be spending time, energy, and money on commoditized parts of the study design. Leverage the speed, expertise, and cost savings of CROs and platform technologies that can get you to data output faster. #synbiobeta2024

SFBN Feed: Making Sense of Scents https://lnkd.in/gntjnt59 In a first, UCSF scientists created a molecular-level, 3D picture of how an odor molecule activates a human odorant receptor. Click here to view original post Click Here to Publish/Feature Your Company or Product News [...] #BayArea #SanFrancisco #Biotech #Lifescience #News

In science, an analyte is the star of the show! It's a substance whose chemical constituents are being identified and measured. This could be anything from a tiny molecule to a giant protein. #Science #Analyte #Investigation #MicrolitGlossary #Microlit #EnablingInnovations

𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡𝐞𝐫𝐬 𝐂𝐡𝐚𝐫𝐚𝐜𝐭𝐞𝐫𝐢𝐬𝐞 𝐚𝐧 𝐀𝐧𝐭𝐢-𝐂𝐑𝐈𝐒𝐏𝐑 𝐏𝐫𝐨𝐭𝐞𝐢𝐧 𝐓𝐡𝐚𝐭 𝐏𝐮𝐥𝐥𝐬 𝐀𝐩𝐚𝐫𝐭 𝐚 𝐂𝐑𝐈𝐒𝐏𝐑-𝐂𝐚𝐬 𝐂𝐨𝐦𝐩𝐥𝐞𝐱 Researchers in Canada and China report the characterisation of AcrIF25, an anti-CRISPR protein that inhibits the type I-F CRISPR-Cas system by dismantling the fully assembled effector complex. The team, led by Alan Davidson at University of Toronto, reports that AcrIF25 is the first example of a protein that disassembles a large and stable macromolecular complex without any external energy source, and presents it as a paradigm for macromolecular complex inhibitors with potential in biotech applications. The findings were published yesterday in Nature. https://lnkd.in/eAp5uSK6 #crisprmedicinenews #crisprmedicine #crispr #cas9 #geneediting

This week, we’re diving into how Raman spectroscopy can revolutionize monitoring and controlling upstream processes in mammalian cell culture. In the featured video, we explore a study showcasing the precision of Raman spectroscopy in analyzing glucose and lactate levels in 25 bioreactors. The results? Impressive accuracy with glucose at +/- 0.3 g/L and lactate at +/- 0.2 g/L! Imagine multiplexing various metabolite profiles simultaneously, integrating data into your control loops, and achieving real-time insights without extensive prep. Pair a Raman probe from Tornado - A Bruker Company with a biocapacitance probe from Aber Instruments Ltd, and you get comprehensive QC with viability data built right in! 📚 Learn more about the versatility of this groundbreaking instrument. Contact ProAnalytics LLC today! 👉 Read Article: https://buff.ly/4biks7j #Bioprocessing #CellCulture #RamanSpectroscopy #UpstreamProcessing #Biotechnology #LabTech

𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡𝐞𝐫𝐬 𝐂𝐡𝐚𝐫𝐚𝐜𝐭𝐞𝐫𝐢𝐬𝐞 𝐚𝐧 𝐀𝐧𝐭𝐢-𝐂𝐑𝐈𝐒𝐏𝐑 𝐏𝐫𝐨𝐭𝐞𝐢𝐧 𝐓𝐡𝐚𝐭 𝐏𝐮𝐥𝐥𝐬 𝐀𝐩𝐚𝐫𝐭 𝐚 𝐂𝐑𝐈𝐒𝐏𝐑-𝐂𝐚𝐬 𝐂𝐨𝐦𝐩𝐥𝐞𝐱 Researchers in Canada and China report the characterisation of AcrIF25, an anti-CRISPR protein that inhibits the type I-F CRISPR-Cas system by dismantling the fully assembled effector complex. The team, led by Alan Davidson at University of Toronto, reports that AcrIF25 is the first example of a protein that disassembles a large and stable macromolecular complex without any external energy source, and presents it as a paradigm for macromolecular complex inhibitors with potential in biotech applications. The findings were published yesterday in Nature. https://lnkd.in/eAp5uSK6 #crisprmedicinenews #crisprmedicine #crispr #cas9 #geneediting

📢 Revolutionizing Bioprocess Monitoring with Spectroscopy! 🌟 Scientists are improving upstream monitoring in bioprocessing using novel ATR-FTIR spectroscopy. 🔍 This technique allows for non-invasive analysis of cell health and productivity. 📊 The study highlighted high accuracy in measuring glucose and lactic acid levels. 🛠️ This approach simplifies monitoring, potentially paving the way for advanced, in-line bioprocess analytics. 💡 Future developments could enhance efficiency in biomanufacturing. #BioprocessUpdates #Bioprocessing #Spectroscopy #ATRFTIR #UpstreamMonitoring #CellHealth #Biomanufacturing #NonInvasiveAnalysis #GlucoseMeasurement #LacticAcid #ProcessAnalytics #InnovationInScience #BiotechResearch #LaboratoryTech #EfficiencyInManufacturing #FutureOfBiotech ▷ Read the full article here: 📎 https://lnkd.in/dJmkA2PK

Based on a table created by Albert Vilella I created this graph of (minimum) sequencing cost vs (maximum) yield. Pretty cool, I didn't really expect such a strong correlation. Also, long read sequencing methods from PacBio and Oxford Nanopore Technologies are doing remarkably well. The original table (with much more info): https://lnkd.in/eusS3MkF #ngs #Bioinformatics.