The Role of Zinc in Wound Healing and Its Food Sources Zinc is an essential trace element that plays a critical role in various biological processes. It is a component of over 300 enzymes and is involved in DNA synthesis, cell division, and protein synthesis. Its importance in wound healing has been the subject of extensive research, revealing its role in cellular repair, immune function, and tissue regeneration. Zinc acts as a co-factor for several enzymes involved in the wound healing process. It is essential for the synthesis of collagen, a protein that provides structural integrity to tissues. Zinc also plays a role in the inflammatory response, helping to control infection and initiate the healing process. Studies have shown that zinc modulates the activity of metalloproteinases, enzymes that break down damaged tissue, thus facilitating tissue repair. Source: www.sciencedirect.com Zinc deficiency can significantly impair the body's ability to heal wounds. A lack of zinc affects cellular metabolism and can lead to delayed wound closure, increased risk of infection, and poor scar formation. Source: www.ncbi.nlm.nih.gov Dietary sources of zinc include animal-based foods like oysters, beef, and chicken, as well as plant-based options like pumpkin seeds, chickpeas, and whole grains. Source: www.nutritiondata.self.com The RDA for zinc varies by age and sex. For adult men, the RDA is 11mg per day, while for adult women, it is 8mg per day. Pregnant and lactating women require higher amounts, around 11-13mg per day. Source: www.ods.od.nih.gov Low levels of zinc can lead to a range of health issues, including impaired immune function, loss of appetite, and delayed wound healing. On the other hand, excessive zinc intake can lead to nausea, vomiting, and inhibition of copper absorption, which can result in neurological issues. Source: www.mayoclinic.org, www.webmd.com Zinc is a vital nutrient for wound healing, playing a multifaceted role in cellular repair, inflammation control, and tissue regeneration. Ensuring adequate zinc intake through a balanced diet can significantly improve wound healing outcomes and overall health. Source: www.antiagingetc.net
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One of the most concerning metabolic health issues, which has been scarcely addressed till now is non alcoholic fatty liver disease(NAFLD).Around 40% of the Indian population is suffering from this disease. It is no brainer , NAFLD is linked with accumulation of fat on the liver & people who have obesity /type 2 diabetes have high risk of/suffer from NAFLD. While starting point of addressing this disease is exercise regularly, eat less sugar, have lot of fibre etc, however there is more to the NAFLD story here- one of the reasons why the disease is never detected at early stage( even before doctor tell you that you have fatty liver stage 1) Yes it is gut & oral microbial dysbiosis. Let us discuss both of them Gut Dysbiosis: There is bidirectional relationship between gut & liver via gut-liver axis. Liver receives 75% of blood supply from the intestine while the liver releases bile acid to metabolise fat. In case of gut dysbiosis, certain microbes &/or their byproducts could move to liver & impact liver functions. Metabolites that impact liver function & could lead to fatty liver include - Bile Acid metabolism: Gut microbiome impacts bile acid pool & conversion of primary to secondary bile acid. Imbalanced gut could lead to low BA synthesis, thereby influencing lipid & glucose metabolism -TMA: Proteobacteria, if active, could produce TMA, a byproduct of choline, which enters the liver & gets converted into TMAO. This leads to choline deficiency which decrease VLDL formation & triglyceride export, thereby causing fat accumulation -Butyrate, an essential short chain fatty acid, plays a key role in regulating liver function & inhibiting cell proliferation in hepatic cells by suppressing sirtuin1 expression. Low level of butyrate directly impacts liver -LPS: endotoxin produced by gut microbes could lead to intestinal permeability which allows bacteria & its products to move to the liver, causing liver injury. Oral Dysbiosis: Wrong nutrition choices & poor oral hygiene could lead to growth & pro-inflammatory activity of P.Gingivalis which could, via oral-liver axis, express virulence factors such as LPS, Gingipain & biofilm formation. This pathpoint could trigger insulin resistance, immune system overactivation & fat accumulation causing liver disease. On the other hand, via oral-gut-liver axis, this specific microbe could move to gut via saliva & trigger inflammation & intestinal permeability, further causing fat accumulation, low butyrate production & increased risk of NAFLD : https://lnkd.in/gnfnQMds Regulate your microbiome to promote production of anti-inflammatory metabolites & suppress pro-inflammatory metabolites to reduce risk of NAFLD at the earliest stage. #gutmicrobiome #oralhealth #obesity #type2diabetes #NAFLD Sakshi Bali Shashi Shekhar M. Dr Kamal Karnatak Rupinder Singh Tarun Kumar Citations https://lnkd.in/gBbgfmuq https://lnkd.in/gtCcMQFs
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Founder-Genefitletics|IEAlumni|Biotech CEO of the Year 2024 (India)|Built Asia’s first biochemistry+mathematics platform for microbiome therapeutics to restore human health|Bringing revolution in preventative oncology
One of the most concerning metabolic health issues, which has been scarcely addressed till now is non alcoholic fatty liver disease(NAFLD).Around 40% of the Indian population is suffering from this disease. It is no brainer , NAFLD is linked with accumulation of fat on the liver & people who have obesity /type 2 diabetes have high risk of/suffer from NAFLD. While starting point of addressing this disease is exercise regularly, eat less sugar, have lot of fibre etc, however there is more to the NAFLD story here- one of the reasons why the disease is never detected at early stage( even before doctor tell you that you have fatty liver stage 1) Yes it is gut & oral microbial dysbiosis. Let us discuss both of them Gut Dysbiosis: There is bidirectional relationship between gut & liver via gut-liver axis. Liver receives 75% of blood supply from the intestine while the liver releases bile acid to metabolise fat. In case of gut dysbiosis, certain microbes &/or their byproducts could move to liver & impact liver functions. Metabolites that impact liver function & could lead to fatty liver include - Bile Acid metabolism: Gut microbiome impacts bile acid pool & conversion of primary to secondary bile acid. Imbalanced gut could lead to low BA synthesis, thereby influencing lipid & glucose metabolism -TMA: Proteobacteria, if active, could produce TMA, a byproduct of choline, which enters the liver & gets converted into TMAO. This leads to choline deficiency which decrease VLDL formation & triglyceride export, thereby causing fat accumulation -Butyrate, an essential short chain fatty acid, plays a key role in regulating liver function & inhibiting cell proliferation in hepatic cells by suppressing sirtuin1 expression. Low level of butyrate directly impacts liver -LPS: endotoxin produced by gut microbes could lead to intestinal permeability which allows bacteria & its products to move to the liver, causing liver injury. Oral Dysbiosis: Wrong nutrition choices & poor oral hygiene could lead to growth & pro-inflammatory activity of P.Gingivalis which could, via oral-liver axis, express virulence factors such as LPS, Gingipain & biofilm formation. This pathpoint could trigger insulin resistance, immune system overactivation & fat accumulation causing liver disease. On the other hand, via oral-gut-liver axis, this specific microbe could move to gut via saliva & trigger inflammation & intestinal permeability, further causing fat accumulation, low butyrate production & increased risk of NAFLD : https://lnkd.in/gpxNmR_X Regulate your microbiome to promote production of anti-inflammatory metabolites & suppress pro-inflammatory metabolites to reduce risk of NAFLD at the earliest stage. #gutmicrobiome #oralhealth #obesity #type2diabetes #NAFLD Sakshi Bali Shashi Shekhar M. Dr Kamal Karnatak Rupinder Singh Tarun Kumar Citations https://lnkd.in/gp7yw-FN https://lnkd.in/gAV838Mf
Decoding the Onset & Progression of NAFLD #nafld #health #fattyliver #fattyliversymptoms
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Exploring the Abundance of Microorganisms in the Body and Cell Damage. #LivingSpringsRetreat #barbaraoneill #causeofailments #healthylifestyle #diseases #naturalremedies #geneticshealing #DNA #DNAdesign #mineraldeficiency #healing #portfolioshorts #shorts #reels 𝗠𝗘𝗗𝗜𝗖𝗔𝗟 𝗗𝗜𝗦𝗖𝗟𝗔𝗜𝗠𝗘𝗥 This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Neither Barbara O'Neill nor the publisher of this content takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All viewers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement or lifestyle program.
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𝐓𝐡𝐞 𝐇𝐞𝐚𝐥𝐢𝐧𝐠 𝐏𝐨𝐰𝐞𝐫𝐬 𝐨𝐟 𝐂𝐥𝐨𝐯𝐞𝐬: 𝐃𝐢𝐬𝐞𝐚𝐬𝐞𝐬 𝐚𝐧𝐝 𝐀𝐢𝐥𝐦𝐞𝐧𝐭𝐬 𝐓𝐡𝐞𝐲 𝐂𝐚𝐧 𝐇𝐞𝐚𝐥 Cloves, the aromatic flower buds of the Syzygium aromaticum tree, have been used for centuries as a spice and a natural remedy in various cultures. Their medicinal properties are attributed to the presence of compounds like eugenol, flavonoids, and tannins. Here, we explore some of the diseases and ailments that cloves can help heal when used as local herbs or home remedies. 1. Toothache and Oral Health: Cloves are widely known for their analgesic and antiseptic properties, making them an effective remedy for toothaches and other oral health issues. Eugenol, the primary compound in cloves, acts as a natural anesthetic and antibacterial age https://lnkd.in/dPNxdWZN
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Barbara O'Neill Discusses Inherited DNA Weaknesses.
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Save the #date, #13.05.2024 #Role of #father's #nutrition in shaping the #development, #wellbeing and #lifetime #health of the #offspring Our #diet and #lifestyle have massive effects on our day to day #health. This event will explore how #social media can influence the #eating #habits of #young people, the effect of inactivity on our #body and how a #father's diet can actually affect an #unborn #baby and its #lifetime health. #Thankyou #pintofscience
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The Wonders of Cloves - https://lnkd.in/dqqTK-Af The article explores the various health benefits of cloves, a common spice with extraordinary properties. It delves into how cloves can aid in digestion, alleviate toothaches, and even improve liver health. Additionally, the article discusses how cloves possess antimicrobial properties that may help fight infections and boost the immune system. It also highlights their potential to regulate blood sugar levels and promote bone health. Overall, the article sheds light on the numerous wonders of cloves and their potential to enhance overall well-being. #cloves #healthbenefits #spices #naturalremedies #seniorhealth #seniorstodaymagazine #seniorstoday #evergreenclubapp
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