Mapping the Biogeographical Distribution of Human Surface Organ Microbiomes - A Clinical Study
#Mysummary
It very interesting question that I have always thought about but how can someone do it practically? Analysing the microbiome of multiple surface organs all at once and look for differences?
Well this study analyzed 1,608 samples from 53 sites across 7 surface organs (oral cavity, esophagus, stomach, small intestine, appendix, large intestine, and skin) in 33 deceased human subjects.
1- Microbial diversity varied dramatically among organs, with the stomach harboring the lowest diversity due to its acidic environment, while the large intestine exhibited the highest diversity.
2- Distinct microbial compositions were observed among organs, with Bacteroides, Parabacteroides, and Fusobacterium enriched in the large intestine, skin, and oral cavity, respectively.
3- Intra-organ sites also displayed unique microbial signatures, such as Corynebacterium and Staphylococcus on the skin, and Aggregatibacter in the jaws of the oral cavity.
#Mythoughts
The approach of taking deceased individuals is smart but I am not sure how relevant it is.
It is important however to recognize that different organs harbor different microbiomes and they are connected! We should stop considering the microbiome as a separate organ while the interactions are diverse!
HAPPY to hear your THOUGHTS and Stay POSITIVE!
#Myinspiration
"We're no longer living in a world of information scarcity, but one of information abundance. The challenge now is not finding information but navigating through it." - Jonas Gahr Støre
Here is the link to the paper: https://lnkd.in/eCAeMtYe
#microbiome #health #science #nutrition
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2wThis is a huge breakthrough - and one we needed desperately before validating any personalized nutrition programs. Love seeing all the new digital twin tech that’s being built out there!