If you don’t know kidney injury has occurred, how can you treat for it? Join Sarah Sweet, DVM to explore how research into novel kidney biomarkers has expanded our understanding of kidney injury and function.
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Assistant Professor at The Ohio State University, Principal Investigator at the Center for Gene Therapy at Nationwide Children's Hospital | $75K NIH Targeted Genome Editor Delivery Award' 23
Dear LinkedIn colleagues and friends, I am happy to announce that my collaborator, Meisam Naeimi Kararoudi, PhD and I won an NIH targeted challenge phase 1 prize on our project aiming to design a programmable non-viral delivery system for CRISPR-based gene therapy. This approach leverages the use of Extracellular vesicles as programmable non-viral delivery vehicles for multiple gene therapy applications such as CRISPR. In our project, we will be using multiple novel technologies under development in my lab and Dr. Kararoudi's lab at Nationwide Children's Hospital. Winning this NIH prize underscores the significant potential of and interest in using extracellular vesicles as promising non-viral delivery vehicles. You can find more details of the challenge here: https://lnkd.in/d3Vmusfm. #extracellularvesicles #exosomes #nih #crispr #biotech #biotechinnovation #genetherapy #innovation #science #technology #columbusohio #geneticdisorders
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Platform trials offer a groundbreaking way to streamline clinical research, but they often struggle with efficient resource allocation to different treatment arms. According to a JAMA Network Open study (Access full article here: https://lnkd.in/eqeD9gAs), randomized platform clinical trials frequently lack clear reporting on their adaptive elements and results. These trials are increasingly favored due to advantages over RCTs, addressing issues of inflexibility, slow timelines, and high costs. CIMS RTSM's powerful Adaptive Randomization feature presents a solution. By dynamically adjusting the probability of patient assignment to different arms based on accumulating data, it helps researchers: ⚡ Prioritize promising therapies: Focus resources on treatments showing the most potential. ⚡ Optimize patient outcomes: Increase the likelihood that patients receive the most beneficial interventions. ⚡ Conserve resources: Reduce costs and accelerate the research process.
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📃Scientific paper: Front cover Abstract: The cover image is based on the Research Article Targeting upregulated RNA binding protein RCAN1.1: a promising strategy for neuroprotection in acute ischemic stroke by Yan Yun et al., https://lnkd.in/eZUfcFhp. [Image: see text] Continued on ES/IODE ➡️ https://etcse.fr/jUc ------- If you find this interesting, feel free to follow, comment and share. We need your help to enhance our visibility, so that our platform continues to serve you.
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#BePartOfResearch - Did you know that The National Institute for Health and Care Research has over 900 studies for Cancers? Find out how you can get involved in research by visiting their website: https://lnkd.in/ebCn9cfu @NIHRtakepart @NIHRresearch #CancerResearch #CancerClinicalTrials #ResearchFunding
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💧 Why settle for anything less than perfection in your analytics for drug production processes? Our UltraPure Water is your lab's best friend, ensuring that pesky enzymes stay far, far away. Here’s why you'll love it: ✨ Produced under stringent #GMP guidelines - because we take purity seriously! ✨ No DNase, no RNase, no worries! ✨ Proven Performance in: Buffer preparation, DNA/RNA purification, DNA sequencing and libraries, Gene mapping, Recombinant DNA and Cloning, PCR analysis, Northern Blot and Southern Blot. So, if you're aiming for excellence in your research and production, Canvax's UltraPure Water is the way to go. Dive into purity with us! ➡️ Check it out now: https://lnkd.in/dXccg4it #Canvax #UltraPureWater #GMP #LifeSciences #Biotechnology #DrugProduction
Canvax | UltraPure Water, DNASE/RNASE - Free
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https://lnkd.in/gGAMKKGq Follow this and the latest organoid and chip news at your new community website: ‘Signet Therapeutics, a biotech company using organoid disease models and AI to advance targeted cancer therapy, today announced that the FDA has granted its IND application for sigx1094 as a potential treatment for diffuse gastric cancer (DGC). This marks a significant milestone as sigx1094 is the first targeted drug candidate for DGC, a disease currently lacking effective treatments. The company is poised to commence a Phase I clinical trial to assess the safety and efficacy of sigx1094 in patients with DGC and other advanced solid tumors' Source FOX40. https://lnkd.in/gGAMKKGq #organoids #organonachip
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A whole series of unique presentations on the latest CAR T cell research presented by STEMCELL Technologies and Scientist.com! Learn more and register for tomorrow’s half-day virtual event, here: https://bit.ly/3VXSCc2 Topics include: ☑️ Enhancing CAR T cell function ☑️ Scaling up non-viral manufacturing of CAR T cells ☑️ Scalable workflows for translational T cell research and T cell therapy development ☑️ Tools and technologies for T cell sourcing, isolation, expansion and activation ☑️ Tips and tricks for qualifying raw/ancillary materials and navigating regulatory hurdles. #TCell #DrugDevelopment
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Starting shortly (3 p.m. EDT): Join the #WorldSepsisDay presentation with Accelerate Diagnostics titled "Rapid, accurate antibiotic response for #sepsis: accelerating phenotypic, actionable diagnostics for improved patient outcomes." https://lnkd.in/e5naZGwD #WSD2023
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Xegen, or the best proof that developing international business works... even if you are not (yet 😉) a multinational company. The pilars: - All Xegen customers are delighted with the quality of the services, whether in France, Germany, Belgium or the US. - ISO13485 certification - Co-design with customers - Transparency Customers are now entrusting us with their new projects 💪 Trust is important, it's earned over time... and it creates long-lasting relationships. Run Xegen, Run ! 😁
CEO, Chief Scientific Officer at XEGEN | Tackling biological challenges using omics data analysis (personalized medicine / life understanding)
Xegen one step forward on the US market I'm pleased to announce that Xegen is now registered on Sam.gov, enabling us to expand our collaborations with US federal entities. We are starting an ambitious project with a US research laboratory funded by the Veterans Affairs, which is the recognition of our uniqueness in multiomics / NGS data analysis and complex results interpretation. More to follow 😉 #NGS, #Analysis, #US
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