CU Cancer Center member Maria Amaya, MD, PhD, is looking at how to improve treatment methods for acute myeloid leukemia with fellow CU researchers. “We think the reason why this leukemia is so aggressive, and why we have a difficult time healing these patients, is because they have these leukemia populations called leukemia stem cells,” Amaya said. “When patients develop leukemia, they have a leukemia stem cell that can give rise to the whole disease, which is what we call the myeloblast.” Learn more about the leukemia research Amaya is a part of here: https://lnkd.in/gJrqwe4r #LeukemiaAwareness #Leukemia #CancerResearch #Oncology
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Check out our new paper in #Cancer #Cell Jiyang Yu Cell Press
B-Cell Development Vulnerability in Leukemia Suggests Novel Combination Therapy A recent breakthrough by scientists at St. Jude Children's Research Hospital has shed light on which tumor cells in B-cell acute lymphoblastic leukemia (B-ALL) resist treatment and how this resistance can be overcome. The researchers were led by senior co-corresponding author Jun Yang, PhD. Their findings of this vulnerability in leukemia informed the development of a new combination therapy that better controlled high-risk B-ALL in mouse models.
B-Cell Development Vulnerability in Leukemia Suggests Novel Combination Therapy
https://www.insideprecisionmedicine.com
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🔬 Dr. Maria Amaya, an assistant professor in the CU Division of Hematology, is spearheading groundbreaking research aimed at advancing treatment methods for acute myeloid leukemia (AML). AML is known for its aggressive nature, affecting primarily older adults with a challenging median age at diagnosis of 69 years. Despite intensive therapies, the relative five-year survival rate stands at only 31.9%, underscoring the urgent need for more effective treatments. "Our goal is to disrupt the leukemia stem cells that drive AML, potentially leading to more durable remissions," explains Dr. Amaya. Her research has identified STAT3's involvement in mitochondrial function and oxidative phosphorylation (OXPHOS), crucial processes for cancer cell survival. By inhibiting STAT3 with a small molecule called "stattic," Dr. Amaya and her team have observed mitochondrial dysfunction and subsequent cell death in leukemia stem cells. Join us in applauding Dr. Maria Amaya and her team for their impactful contributions to leukemia research and patient care. Read the full story below! 👏 https://bit.ly/4cH6E79 #LeukemiaResearch #MedicalInnovation #HealthcareScience #CUAnschutz #ResearchHighlight #AMLTreatment
CU Researcher Works to Improve Acute Myeloid Leukemia Therapies
news.cuanschutz.edu
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Passionate Healthcare Innovator | Expert in Sales & Marketing | Driven by Personal Experience to Advance Cancer Screening & Early Detection | Open to New Opportunities
Exciting Developments in Cancer Screening Technology! 🚀 Hi everyone, I came across an article recently that discusses a groundbreaking advancement in cancer screening technology. A study at Penn Medicine found that two chronic lymphocytic leukemia (CLL) patients treated with CAR T cell therapy have remained in remission for over a decade, highlighting the long-term effectiveness and potential of this personalized cancer treatment. This is GROUNDBREAKING! As someone deeply passionate about the healthcare field and driven by personal experience, these advancements give me hope and reinforce my commitment to this industry. It’s innovations like these that inspire me to continue working towards making a difference in cancer screening and early detection. I’d love to hear your thoughts on this development. How do you think this technology will impact the future of cancer treatment and patient outcomes? #Healthcare #Biotech #CancerScreening #Oncology #Innovation #MedicalDevices #EarlyDetection #HealthcareTechnology #ProfessionalNetworking #CareerDevelopment #Pennmedicine Best, Ashley
Study of Patients with Leukemia Remission after CAR T Therapy
pennmedicine.org
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#ICYMI At the Lymphoma, Leukemia & Myeloma Congress, John Allan, MD, Weill Cornell Medicine, discussed novel updates in the #CLL treatment landscape, highlighting studies that focused on the use of #BTK inhibitor combination treatments for CLL. Learn more: https://lnkd.in/dEhSJdat #Oncologist #OncologyNews #Oncology
Novel Updates in the Chronic Lymphocytic Leukemia Treatment Landscape
hmpgloballearningnetwork.com
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Unlocking New Lifesaving Treatment for Blood Cancer Patients - Research from Sylvester Comprehensive Cancer Center and colleagues reveals a groundbreaking approach using an older drug to expand donor options for high-risk blood cancer patients. This innovative method offers hope for patients, particularly those from underrepresented groups. The ASCO and EHA presentations share promising outcomes and advancements. Read more about this transformative study here. #BloodCancerTreatment #StemCellTransplantation #ResearchBreakthroughs #CancerCareInnovations
https://go.upcontent.com/093b69d9-ceae-475d-9047-2e9d8c1aaa24
eurekalert.org
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Therapies targeting the biological mechanisms of pre-leukemic #MDS may improve patient outcomes, according to data presented at the #SOHO2023 annual meeting by Juan Jose Rodriguez-Sevilla, PhD, MD Anderson Cancer Center. Learn more: https://lnkd.in/eVFcb9sS Society of Hematologic Oncology #Oncology #OncologyNews #MyelodysplasticSyndrome
Exploring Potential Novel Therapeutic Interventions for Patients With Early-Stage Myelodysplastic Syndromes
hmpgloballearningnetwork.com
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Founder - CEO FrizeMedia Content / Influencer Marketing Digital / Online Advertising Social Media GrowthHacking SEO
A large number of cases of cancer are identified to be leukemia. Leukemia is a sort of cancer of the blood and marrow. The disease is characterized through the overproducing of immature blood cells (stem cells) that are not able to fully develop and to carry out the activities of normal blood cells. According to their functions and structure, there are three different types of cells within the normal blood: red blood cells, white blood cells and platelets. Through the process of hematopoiesis, these three types of blood cells are developed from a distinctive type of blood cell called stem cell. Stem cells divide and go through several stages of development to finally form a mature blood cell of a particular type, with a certain, distinctive function in the body.
#Leukemia - General Aspects Symptoms And Causes #cancer #FrizeMedia
internetbusinessideas-viralmarketing.com
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Let’s Build a Better World Together. Multidisciplinary Artist / Designer. UCLA Design | Media Arts Alum.
The future of immunity
UCLA researchers have developed a new method to engineer more powerful immune cells that can be used for an “off-the-shelf” cancer immunotherapy in which immune cells from a single cord-blood donor can be used to treat multiple patients. @UCLAHealth https://ucla.in/4blwtJI
Novel technology positions ‘off-the-shelf' cancer immunotherapy for the clinic
newsroom.ucla.edu
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Founder - CEO FrizeMedia Content / Influencer Marketing Digital / Online Advertising Social Media GrowthHacking SEO
A large number of cases of cancer are identified to be leukemia. Leukemia is a sort of cancer of the blood and marrow. The disease is characterized through the overproducing of immature blood cells (stem cells) that are not able to fully develop and to carry out the activities of normal blood cells. According to their functions and structure, there are three different types of cells within the normal blood: red blood cells, white blood cells and platelets. Through the process of hematopoiesis, these three types of blood cells are developed from a distinctive type of blood cell called stem cell. Stem cells divide and go through several stages of development to finally form a mature blood cell of a particular type, with a certain, distinctive function in the body.
#Leukemia - General Aspects Symptoms And Causes #cancer #FrizeMedia
internetbusinessideas-viralmarketing.com
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Doctoral Researcher at University of Helsinki | R programming | Single-cell RNAseq data analysis | Drug combination optimization
Good news! Our article "Tracing back primed resistance in cancer via sister cells" has been published in Nature Nommunications. It reported a new single-cell lineage tracing method for uncovering the pre-existing resistant cellular states in cancer. Here is the press release for our study: https://lnkd.in/dNcRwvFh #singlecellanalysis #rnaseq #drugresistance #drugrepurposing #anticancer #cancerresearch #ovariancancer #chemotherapy #immunotherapy
Sister cells uncover pre-existing resistant states in cancer | University of Helsinki
helsinki.fi
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