Worldwide Clinical Trials’ Post

Ever wondered why patients juggle three pills instead of one with the same ingredients? The same curiosity led us to explore the benefits of combining multiple drugs into one formulation, which makes drug administration more convenient for patients. In a systematic review of 109 studies, we compared Single-tablet combination therapies (STCTs) as well as fixed-dose combinations ([FDCs] of non-tablet formulations) with the equivalent active compounds and doses in loose-dose combinations (LDCs) across four evidence domains: clinical trials, real-world evidence (RWE), health-related quality of life (HRQoL) studies, and economic evaluations. Our findings? Patients on STCTs not only showed significantly higher adherence and persistence compared to LDCs but also enjoyed positive perks – think reduced need for add-on medications, better blood pressure control, and improved hemoglobin A1C. Additionally, FDCs emerged with cost savings associated with lower medical costs and reduced healthcare resource utilization. Intrigued? Dive into our recently published article here: https://lnkd.in/eZjkBzwT

Thoughts on this? >> Agios plans thalassemia filing in US after unveiling data in transfusion-dependent patients >> Comment below! >>> lqventures.com #strategy #competitiveintelligence #marketing #pharmaceutical #productmarketing #healthcare #biotech #pharma

Thoughts on this? >> Agios plans thalassemia filing in US after unveiling data in transfusion-dependent patients >> Comment below! >>> lqventures.com #strategy #competitiveintelligence #marketing #pharma #healthcare #pharmaceutical #productmarketing #biotech

In a recent article for Healthline Media, OMA President Dr. Angela Fitch speaks on the increase in pricing for popular GLP-1 medications, including Ozempic and Mounjaro. The article discusses the high demand for anti-obesity medications and what the price increases might mean for patients taking the medications. Read the full article at https://bit.ly/48cYj8x #oma #obesity #medication #antiobesitymedication

I would like to provide a brief overview of the pharmacotherapy options available for treating heart failure and the latest breakthroughs in this field. #evidencebasedmedicine #HeartHealth #Pharmacotherapy #MedicalAdvancements #medicalaffairs

There have now been several such analyses (including from Novo itself) showing remarkably consistent numbers for the 1st year. I believe this is the first one with a 2 year data point. Semaglutide showing additional attrition from 1 in 3 to just 1 in 4 users. Some thoughts: 1. Injections are a huge problem. 2. GI tolerability is an even bigger problem. 3. I do not believe the theory that patients stop because they have reached their target weight. If you’ve struggled with obesity you don’t stop your life-altering therapy just because you are no longer obese. It’s a nonsensical explanation. You wouldn’t apply it to any other medical condition. 4. We need easy to use and much more tolerable oral daily drugs. 5. RCTs are not reflective of RWE (this should be obvious).

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Clinical Trial Shows Drug Developed to Treat Uncontrolled Hypertension Significantly Lowers Blood Pressure #ClinicalTrial #HypertensionTreatment #BloodPressure #MedicalResearch #Healthcare #DrugDevelopment #HealthNews #CardiovascularHealth #HypertensionResearch #MedicalBreakthrough #BloodPressureControl #HealthScience #HeartHealth #MedicineAdvancements #HighBloodPressure #Pharmaceuticals #HealthDiscoveries #HypertensionMedication #MedicalInnovation #ResearchFindings