Galleri Test

The Galleri test requires a single blood draw that can easily be incorporated into your routine wellness visit. At only 0.5%, the test has a low false positive rate (among those without cancer).¹⁻² Nearly 99% of people who take the Galleri test will receive a No Cancer Signal Detected result — which is exactly what you want to hear.³ Learn more about the science behind the test: https://bit.ly/46qpldj #MultiCancerEarlyDetection #MCED #CancerScreening Rx only. Important Safety Information: http://bit.ly/33m8pFa The Galleri test does not detect a signal for all cancers and not all cancers can be detected in the blood. False positive and false negative results do occur. The Galleri test should be used in addition to healthcare provider recommended screening tests. A Galleri result of No Cancer Signal Detected does not rule out cancer. The Galleri test identifies DNA in the bloodstream shed by cancer cells and does not predict future genetic risk for cancer. References: 1. Klein EA, Richards D, Cohn A, et al. Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set. Ann Oncol. 2021 Sep;32(9):1167-77. doi: 10.1016/j.annonc.2021.05.806 2. Schrag D, Beer TM, McDonnell CH, et al. Blood-based tests for multi-cancer early detection (PATHFINDER): a prospective cohort study. Lancet. 2023;402:1251-1260. doi: 10.1016/S0140 6736(23)01700-2 3. National Cancer Institute NIH. Age and Cancer Risk. https://bit.ly/4dIEeu7

When Mike was diagnosed with tonsil cancer,* he chose to receive treatment at Mercy because their care team could see him sooner than any other provider he contacted. Patient experience is a priority for Mercy, whose care team expedites diagnostic workup and treatment for patients who test positive with the Galleri multi-cancer early detection test. Hear the impact of Mercy’s seamless care coordination on this patient’s experience: https://bit.ly/4dAU2PS #CancerScreening #MultiCancerEarlyDetection See Important Safety Information: http://bit.ly/33m8pFa Galleri should be used in addition to healthcare provider recommended screening tests. The Galleri test does not detect a signal for all cancers and not all cancers can be detected in the blood. False positive and false negative results do occur. Galleri is a screening test and does not diagnose cancer. Diagnostic testing is needed to confirm cancer. *Based on a clinical study of people ages 50 to 79, around 1% are expected to receive a Cancer Signal Detected result. After diagnostic evaluation, around 40% of these people are expected to have a confirmed cancer diagnosis. The overall sensitivity in study participants with head and neck cancer was 85.7% (63.2% for stage I, 82.4% for stage II, 84.2% for stage III, 96.0% for stage IV).

“Mercy is taking the approach of precision-based medicine to guide our treatment recommendations to improve quality and the care that we provide our patients,” says Daniel Mackey, MD, medical oncologist. When describing the Galleri test, Mackey says, “This opens a whole new frontier, where we might have more treatment options.” Watch as Mackey shares how the Galleri test helps advance precision-based medicine at St. Louis-based Mercy health system. Hear the full story: https://bit.ly/3WTrKc8 #CancerScreening #MultiCancerEarlyDetection See Important Safety Information: http://bit.ly/33m8pFa Galleri should be used in addition to healthcare provider recommended screening tests. The Galleri test does not detect a signal for all cancers and not all cancers can be detected in the blood. False positive and false negative results do occur. Galleri is a screening test and does not diagnose cancer. Diagnostic testing is needed to confirm cancer.

We’re looking forward to connecting with International Association of Fire Fighters (IAFF) leaders from across the US at #IAFFConvention24. Join us to learn how you can be more proactive about your health with the Galleri multi-cancer early detection screening test. #Galleri #MultiCancerEarlyDetection #FireFighters Rx only. See Important Safety Information: http://bit.ly/33m8pFa Galleri should be used in addition to healthcare provider recommended screenings. The Galleri test does not detect a signal for all cancers and not all cancers can be detected in the blood. False positive and false negative results do occur.

While doctors can currently screen for 5 specific cancers individually, nearly 70% of cancers have no recommended screening tests.¹⁻²* Adding the Galleri test gives your doctor the chance to screen for many of the deadliest cancers, including those with no recommended screening tests today.¹⁻³* Rx only. Learn more and See Important Safety Information: http://bit.ly/33m8pFa #CancerScreening #DetectCancerEarly #Galleri The Galleri test does not detect a signal for all cancers and not all cancers can be detected in the blood. False positive and false negative results do occur. Galleri is a screening test and does not diagnose cancer. Diagnostic testing is needed to confirm cancer. The Galleri test should be used in addition to healthcare provider recommended screening tests. *Assumes screening is available for all prostate, breast, cervical, and colorectal cancer cases and 43% of lung cancer cases (based on the estimated proportion of lung cancers that occur in screen-eligible individuals older than 40 years).

 References: 1. American Cancer Society. Cancer facts & figures 2022. https://lnkd.in/d2jQGCEY [GRAIL, LLC. Data on file: GA-2021-0065] 2. Surveillance, Epidemiology, and End Results (SEER) Program SEER*Stat Database: Incidence - SEER 18 Regs Research Data, Nov 2017 Sub. Includes persons aged 50+ diagnosed 2006-2015. [GRAIL, LLC. Data on file: GA-2021-0065.] 3. Klein EA, Richards D, Cohn A, et al. Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set. Ann Oncol. 2021 Sep;32(9):1167-77. doi: 10.1016/j.annonc.2021.05.806

This #BreastCancerResearchDay, we want to thank the dedicated cancer researchers who are committed to helping us learn more and find new ways to prevent, detect, and treat this disease. #BreastCancer #CancerResearch #CancerDetection Reference: 1. World Breast Cancer Research Day. Tower Cancer Research Foundation. [cited 2024 Jun 07]. https://lnkd.in/eg2WJEq5

Do more to screen for cancer by adding the Galleri test. When used in addition to recommended screening tests, Galleri can increase the chance of finding cancer early.¹⁻³ Discover multi-cancer early detection testing with Galleri: https://bit.ly/4cjhd0t #Summer #Wellness #Galleri #CancerScreening Rx only. Important Safety Information: http://bit.ly/33m8pFa The Galleri test does not detect a signal for all cancers and not all cancers can be detected in the blood. False positive and false negative results do occur. The Galleri test should be used in addition to healthcare provider recommended screening tests. References: 1. Schrag D, Beer TM, McDonnell CH, et al. Blood-based tests for multi-cancer early detection (PATHFINDER): a prospective cohort study. Lancet. 2023;402:1251-1260. https://lnkd.in/e88jG9kd 2. US Preventive Services Task Force. A,B,C grade recommendations, cancer, screenings. [cited 2023 Oct 23]. https://bit.ly/3PAPU7r 3. Hackshaw A, Cohen SS, Reichert H, et al. Estimating the population health impact of a multi-cancer early detection genomic blood test to complement existing screening in the US and UK. Br J Cancer. 2021 Nov;125 (10): 1432-144. doi: 10.1038/s41416-021-01498-4.

Doctors today can screen individually for 5 specific cancers and 70% of cancers have no recommended screening tests.¹⁻²* Adding the Galleri test to recommended cancer screening tests can increase your chance of finding cancer early.³⁻⁵ Talk to your doctor about multi-cancer early screening with the Galleri test: https://bit.ly/4cjhd0t #MultiCancerEarlyDetection #MCED #CancerScreening #Healthcare Rx only. Important Safety Information: http://bit.ly/33m8pFa The Galleri test does not detect a signal for all cancers and not all cancers can be detected in the blood. False positive and false negative results do occur. Galleri is a screening test and does not diagnose cancer. Diagnostic testing is needed to confirm cancer. The Galleri test should be used in addition to healthcare provider recommended screening tests. *Assumes screening is available for all prostate, breast, cervical, and colorectal cancer cases and 43% of lung cancer cases (based on the estimated proportion of lung cancers that occur in screen-eligible individuals older than 40 years). References: 1. US Preventive Services Task Force. Recommendations Cancer. Accessed 7Mar2023. https://bit.ly/3PAPU7r. 2. Surveillance, Epidemiology, and End Results (SEER) Program SEER*Stat Database: Incidence - SEER 18 Regs Research Data, Nov 2017 Sub. Includes persons aged 50+ diagnosed 2006-2015. [GRAIL, LLC. Data on file: GA-2021-0065.] 3. Schrag D, Beer TM, McDonnell CH, et al. Blood-based tests for multi-cancer early detection (PATHFINDER): a prospective cohort study. Lancet. 2023;402:1251-1260. doi: 10.1016/S0140 6736(23)01700-2 4. US Preventive Services Task Force. A,B,C grade recommendations, cancer, screenings. [cited 2023 Oct 23]. https://bit.ly/3PAPU7r 5. Hackshaw A, Cohen SS, Reichert H, et al. Estimating the population health impact of a multi-cancer early detection genomic blood test to complement existing screening in the US and UK. Br J Cancer. 2021 Nov;125 (10): 1432-144. doi: 10.1038/s41416-021-01498-4

“By the time you realize you have lung cancer, it’s often too late to do anything about it.” This #WorldLungCancerDay 🫁, we’re sharing Rich and Staci’s experience with the Galleri test to raise awareness for multi-cancer early detection testing and the importance of recommended cancer screenings. After learning about the Galleri test from Rich’s family member, Rich and Staci talked to their doctor and decided to take the test. Staci’s test came back negative, but Rich received a Cancer Signal Detected result with a predicted Cancer Signal Origin for lung cancer. After imaging and a biopsy, the lung cancer diagnosis was confirmed, and Rich started treatment right away. Rx only. Learn more about Galleri and See Important Safety Information: http://bit.ly/33m8pFa #LungCancer #MultiCancerEarlyDetection #MCED #CancerScreening Galleri should be used in addition to healthcare provider recommended screening tests. The Galleri test does not detect a signal for all cancers and not all cancers can be detected in the blood. False positive and false negative results do occur. Galleri is a screening test and does not diagnose cancer. Diagnostic testing is needed to confirm cancer. Based on a clinical study of people ages 50 to 79, around 1% are expected to receive a Cancer Signal Detected”result which includes predicted Cancer Signal Origin(s). After diagnostic evaluation, around 40% of these people are expected to have a confirmed cancer diagnosis. The overall sensitivity in study participants with lung cancer was 74.8% (21.9% for stage I, 79.5% stage II, 90.7% stage III, 95.2% stage IV).

The Galleri multi-cancer early detection test is transforming cancer screening with ability to screen for a “fingerprint” of the deadliest cancers before they become symptomatic, including those without recommended screening tests today.¹ Discover the importance of multi-cancer early detection screening: https://bit.ly/4cjhd0t #Galleri #MultiCancerEarlyDetection #CancerScreening See Important Safety Information: http://bit.ly/33m8pFa Galleri should be used in addition to healthcare provider recommended screening tests. The Galleri test does not detect a signal for all cancers and not all cancers can be detected in the blood. False positive and false negative results do occur. A Galleri result of No Cancer Signal Detected does not rule out cancer. Based on a clinical study of people ages 50 to 79, around 1% are expected to receive a “Cancer Signal Detected” result. After diagnostic evaluation, around 40% of these people are expected to have a confirmed cancer diagnosis. References: 1. Klein EA, Richards D, Cohn A, et al. Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set. Ann Oncol. 2021;32(9):1167-77. DOI: https://bit.ly/3Pn3RqX.