LNP Development Event Series

❗ Early bird Discount is Expiring Soon ❗ This Friday marks your last chance to take advantage of discounts of up to $1,100 for the 3rd Annual LNP Immunogenicity & Toxicity Summit. Join leaders from Moderna, BioNTech, Pfizer, AstraZeneca, AbbVie, Beam Therapeutics, Orna Therapeutics and lots more at the only event dedicated to advancing and improving prediction, characterization and monitoring of LNP safety. Secure your place ➡️ https://ter.li/z5g3uh

❗JUST LAUNCHED – The 3rd LNP Immunogenicity & Toxicity Summit   📈 Assess LNP toxicity while predicting and monitoring clinical safety to ensure regulatory compliance for vaccines, gene and cell therapies   💡Returning as the only forum solely dedicated to assessing non-clinical and clinical LNP safety risk, by optimizing in vitro and in vivo tools for prediction, dosing and route of administration, characterize the immune response, and nanoparticle design to assess and improve safety in vaccines, gene and cell therapies.   🔎 Join experts from Pfizer, AstraZeneca, Moderna, Eli Lilly and Company and Beam Therapeutics, as they dive deep into mechanisms of toxicity, optimal delivery strategy, PEG-lipid alternatives and in vitro prediction, to progress development of safer LNP-delivered therapeutics.   Across the 3 days you will gain insights into: ✔ Non-clinical assessment of LNP safety, including in vitro and in vivo models to advance prediction and risk assessment ✔ Case studies showcasing clinical data and immune-monitoring, as well as next-generation LNPs with optimal safety profiles ✔ Discussions on current regulatory guidelines, to support submissions and filings ✔ Solutions to control anti-PEG reactions, and refined LNP design to prevent immunogenic reactions ✔ Strategies to improve delivery, dosing and routes of administration to enhance specificity and mitigate adverse effects   View the full program here: https://ter.li/r7xq78   The LNP team hope to see you in Boston this December!

❗BRAND NEW AGENDA – The 2nd LNP Characterization & Analytical Development Summit 📈 Revolutionizing Your LNP Drug Product Quality, Safety, Efficacy & Regulatory Compliance 💡 With resources tightened in parallel to regulatory scrutiny growing, the need for advanced analytical strategy has never been more pressing, to create bulletproof regulatory submissions. Diversity of formulations has spread excitement across the LNP field, however this brings more complex challenges when seeking thorough characterization data packages to advance from phase to phase. 🔎 Lipid nanoparticle professionals with expertise in characterization, analytical development, quality, regulatory and more have committed their time to the 2nd LNP Characterization & Analytical Development Summit to reevaluate their strategy as 2024 closes to hit the ground running in 2025. Some of the challenges addressed across the 3 days includes: 🔸 Focus in on the latest strategies to comprehensively characterize structural properties of complex lipid nanoparticles, including both static and dynamic properties to create an all-encompassing characterization profile of your LNP with NeoVac 🔸 Maximize translatability through seamless transition from in vitro to in vivo assay development to ensure efficiency of phase to phase development with Moderna 🔸 Manage the diverse interactions with LNP components and the payload, indicating the endosomal release outcomes to evolve with the increasingly complex drug products with Prime Medicine, Inc. 🔸 Develop a robust potency assay to reflect the mechanisms of action and total functionality of the LNP with Tessera Therapeutics View the full program here – https://ter.li/22norl For more information, please feel free to drop me a message and I would be more than happy to help. The LNP team hope to see you in Boston this November! Kieran Crewe Stephanie N. Clementine Aston #lnp #nanoparticle #drugdelivery #lipid #liposome #mrna #crispr #geneediting #nonviral

❗BRAND NEW AGENDA – The 2nd LNP Characterization & Analytical Development Summit 📈 Revolutionizing Your LNP Drug Product Quality, Safety, Efficacy & Regulatory Compliance 💡 With resources tightened in parallel to regulatory scrutiny growing, the need for advanced analytical strategy has never been more pressing, to create bulletproof regulatory submissions. Diversity of formulations has spread excitement across the LNP field, however this brings more complex challenges when seeking thorough characterization data packages to advance from phase to phase. 🔎 Lipid nanoparticle professionals with expertise in characterization, analytical development, quality, regulatory and more have committed their time to the 2nd LNP Characterization & Analytical Development Summit to reevaluate their strategy as 2024 closes to hit the ground running in 2025. Some of the challenges addressed across the 3 days includes: 🔸 Focus in on the latest strategies to comprehensively characterize structural properties of complex lipid nanoparticles, including both static and dynamic properties to create an all-encompassing characterization profile of your LNP with NeoVac 🔸 Maximize translatability through seamless transition from in vitro to in vivo assay development to ensure efficiency of phase to phase development with Moderna 🔸 Manage the diverse interactions with LNP components and the payload, indicating the endosomal release outcomes to evolve with the increasingly complex drug products with Prime Medicine, Inc. 🔸 Develop a robust potency assay to reflect the mechanisms of action and total functionality of the LNP with Tessera Therapeutics View the full program here – https://ter.li/22norl For more information, please feel free to drop me a message and I would be more than happy to help. The LNP team hope to see you in Boston this November! Kieran Crewe Stephanie N. Clementine Aston #lnp #nanoparticle #drugdelivery #lipid #liposome #mrna #crispr #geneediting #nonviral

🔦 Speaker Spotlight 🔦 Join Kinkini Roy, PhD and 80+ LNP experts to discuss critical strategies to develop stable, safe and site specific LNP drug products at the 3rd Lipid Nanoparticles Development Europe Summit (24-26 September, Berlin). Take a look at the agenda: https://ter.li/1dmn5 We caught up with Kinkini Roy, PhD recently, who told us how excited they are to be presenting their work alongside Sandipan Dawn, PhD in an exclusive deep-dive workshop titled ”Exploring the Rise of LNP Alternative Drug Delivery Systems”. In this hands-on session, they will compare the challenges faced with LNPs alongside polymeric systems, pinpointing translatable learnings to take forward. See full details of their session: https://ter.li/1dmn5s Unite with these industry leaders at the ultimate end-to-end LNP development discussion, to accelerate the clinical development of lipid nanoparticles and advance the therapeutic potential for mRNA, siRNA, CRISPR, cell therapy and lots more. #LipidNanoparticles #DrugDevelopment #LNP #Therapeutics #mRNA #siRNA #CRISPR #CellTherapy #Pharma #Biotech #Innovation

BRAND NEW Speakers Alert! With the latest data and brand new speakers for 2024, the 3rd Lipid Nanoparticles Development Europe Summit in Berlin this September is providing the most up-to-date insights into LNP development and innovation. See the full speaker list: https://ter.li/d2pkqu Gain the answers to all your LNP questions from Bayer, CureVac, Pantherna Therapeutics GmbH, Ethris, Insmed Incorporated and more! Check out the agenda: https://ter.li/d2pkqu

Exciting to see one of our expert speakers Rongjun Chen and their team from Imperial College London partnering with GSK on a new collaboration to eradicate the expensive cold-chain storage process of RNA vaccines. Hear from Rongjun and 20+ other incredible speakers at the 3rd Lipid Nanoparticles Development Europe Summit this September in Berlin. Check out the full speaker list: https://ter.li/ij1v5w https://lnkd.in/ezmifQAZ

Have you heard about the revolutionary partnership between CordenPharma and Certest? Teaming up to add ionisable lipids into their LNP formulations, they're advancing the commercialisation of xRNA/xDNA.   📈 Stay ahead of the LNP curve by joining us at the 3rd Lipid Nanoparticles Development Europe Summit, the only industry-focused LNP summit in Europe.   Check out the newly-released agenda: https://ter.li/mp19m3   Unite with 100+ LNP discovery, formulation, characterisation, and manufacturing experts this September to learn and advance your clinical progress.   🚨 Even better, register by midnight this Friday to save €1,100! https://ter.li/iuxakw

📢 BRAND NEW AGENDA RELEASE 📢 Fancy joining the LNP community in Berlin this September?