Did you know that #chronicspontaneousurticaria (CSU) is not a superficial disease but thought to be driven by mast cell activation? While the exact pathogenesis is unknown, one pathway leading to mast cell activation is Bruton's tyrosine kinase (BTK) signaling which mediates the release of histamine and other inflammatory mediators leading to common CSU symptoms including itching, hives and angioedema. To learn more, explore educational resources related to #CSU on our website. https://lnkd.in/eDtbZqxj #dermatology #allergy
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Committed to providing US health care professionals medical and scientific information about Novartis products and disease education. See our community guidelines: http://bit.ly/2JnT2CP. If you have a medical inquiry, please contact us via http://bit.ly/31YWY3F or call us at 1-844-NVSocial. Our posts are for US HCP audiences only. • Please be patient; sometimes responses take time. • Please do not include your personal information in your posts. • We will respond to your questions/comments M-F, 9a-5p EST (no holidays). • The purpose of our posts is to share disease state education and congress information. We reserve the right to hide or remove any post that mentions specific product(s) or treatment(s) as that is not the intent of our posts. • If needed, we’ll show you how to get us your contact and case info securely. • We reserve the right to engage with posts on a case-by-case basis; not all posts will be acknowledged or responded to. • Novartis Pharmaceuticals Corporation does not endorse and is not responsible for the content of third-party links we may share. • Replying to or mentioning users does not imply our endorsement.
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Updates
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BCR::ABL is a common and well-understood oncoprotein in CML. At Novartis, we continue to investigate BCR::ABL1 in our commitment to CML. See how we are exploring CML at SOHO. Visit us at Booth 108. #SOHO2024
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Increased levels of BAFF may play a role in B-cell driven autoimmune diseases. Find out how Novartis is reimagining medicine and researching ways to target BAFF signaling in ITP and wAIHA at SOHO. Visit us at Booth 108. #SOHO2024
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Learn more about #LDL-C goal attainment and the impact of baseline demographics from the phase 3 VICTORION-INITIATE clinical trial at the #ESC2024 congress! Dr. Peter P. Toth will present his poster on #LDL-C goal attainment from 15:00-15:50 and Dr. Michael Koren will discuss baseline demographics from 16:00-16:50 on August 30th at Station 4 Research Gateway.
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Interested in learning more about chronic spontaneous urticaria (#CSU)? Diagnostic delays and suboptimal management of CSU may impact quality of life, including work productivity and performance. To gain perspective on best practices for the assessment, diagnosis, and management of CSU, watch our video series on Dermatology Times. https://lnkd.in/eu2pek7v #dermatology #allergy #ChronicSpontaneousUrticaria
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Novartis is committed to raising awareness of IgA nephropathy (IgAN) through education on its disease pathogenesis, which involves activation of the complement and endothelin systems in hit 4 of the multihit mechanism of disease (MOD). Watch this short video to learn more. #kidneydisease
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Interested in learning more about the management of atherosclerotic cardiovascular disease (#ASCVD)? Explore our new interactive patient case study in the award-winning Cardiovascular Halls of Science. #Cardiology https://lnkd.in/ehzJgeBa
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Did you know that Bruton's tyrosine kinase (BTK) signaling plays a role in chronic spontaneous urticaria (CSU) pathophysiology? BTK mediates mast cell activation, degranulation, and release of inflammatory mediators, which may lead to the symptoms of #CSU such as itch, wheals, and angioedema. This mast cell activation occurs through crosslinking of immunoglobulin (Ig)E by autoallergens or IgG, or crosslinking of high-affinity IgE receptor by IgG. To learn more, explore CSU resources for HCPs on our website. https://lnkd.in/eTfKbCWb #dermatology #allergy
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Chronic spontaneous urticaria (CSU) is an unpredictable skin condition, with limited treatment options and diagnostic delays. The latest publication in Dermatology and Therapy discusses practical considerations to diagnosing and managing #CSU
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Attending #ASPC? Come see us at Booth 8 to explore educational resources about #KnowLp(a)! Learn about updated screening recommendations, view videos featuring medical experts, and review infographics with important information about this independent, genetic, and causal risk driver for CVD. For more, check out our award-winning Halls of Science and Innovation: https://lnkd.in/eNesYTsx
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