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Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci
Kristina Beck, Mandy M. Peak, Takayuki Ota, David Nemazee, Cornelis Murre
J Exp Med. 2009 Sep 28; 206(10): 2271–2284. doi: 10.1084/jem.20090756
PMCID:
PMC2757879
Abstract Article PDF–5.1M

Is Cited by the Following 60 Articles in this Archive:

Exclusive Characteristics of the p.E555K Dominant-Negative Variant in Autosomal Dominant E47 Deficiency
Takanori Utsumi, Miyuki Tsumura, Masato Yashiro, Zenichiro Kato, Kosuke Noma, Fumiaki Sakura, Reiko Kagawa, Yoko Mizoguchi, Shuhei Karakawa, Hidenori Ohnishi, Charlotte Cunningham-Rundles, Peter D. Arkwright, Masao Kobayashi, Hirokazu Kanegane, Dusan Bogunovic, Bertrand Boisson, Jean-Laurent Casanova, Takaki Asano, Satoshi Okada
J Clin Immunol. 2024; 44(7): 167. Published online 2024 Jul 29. doi: 10.1007/s10875-024-01758-x
Correction in:
J Clin Immunol. 2024; 44(8): 178.
PMCID:
PMC11286708
Abstract Article PDF–4.5M
Exclusive Characteristics of the p.E555K Dominant-Negative Variant in Autosomal Dominant E47 Deficiency
Takanori Utsumi, Miyuki Tsumura, Masato Yashiro, Zenichiro Kato, Kosuke Noma, Fumiaki Sakura, Reiko Kagawa, Yoko Mizoguchi, Shuhei Karakawa, Hidenori Ohnishi, Charlotte Cunningham-Rundles, Peter D. Arkwright, Masao Kobayashi, Hirokazu Kanegane, Dusan Bogunovic, Bertrand Boisson, Jean-Laurent Casanova, Takaki Asano, Satoshi Okada
J Clin Immunol. 2024; 44(7): 167. Published online 2024 Jul 29. doi: 10.1007/s10875-024-01758-x
Correction in:
J Clin Immunol. 2024; 44(8): 178.
PMCID:
PMC11286708
Abstract Article PDF–4.5M
Kidins220 regulates the development of B cells bearing the λ light chain
Anna-Maria Schaffer, Gina Jasmin Fiala, Miriam Hils, Eriberto Natali, Lmar Babrak, Laurenz Alexander Herr, Mari Carmen Romero-Mulero, Nina Cabezas-Wallscheid, Marta Rizzi, Enkelejda Miho, Wolfgang WA Schamel, Susana Minguet
eLife. 2024; 13: e83943. Published online 2024 Jan 25. doi: 10.7554/eLife.83943
PMCID:
PMC10810608
Abstract Article PDF–3.9M
SH2 domain-containing inositol 5-phosphatases support the survival of Burkitt lymphoma cells by promoting energy metabolism
Florian Mayr, Vanessa Kruse, Dominik C. Fuhrmann, Sebastian Wolf, Jens Löber, Saed Alsouri, Nadia Paglilla, Kwang Lee, Björn Chapuy, Bernhard Brüne, Thorsten Zenz, Björn Häupl, Thomas Oellerich, Michael Engelke
Haematologica. 2024 May 1; 109(5): 1445–1459. Published online 2023 Nov 2. doi: 10.3324/haematol.2023.283663
PMCID:
PMC11063853
Abstract Article PDF–3.7M
Temporal analyses reveal a pivotal role for sense and antisense enhancer RNAs in coordinate immunoglobulin lambda locus activation
Zeqian Gao, Alastair L Smith, James N F Scott, Sarah L Bevington, Joan Boyes
Nucleic Acids Res. 2023 Oct 27; 51(19): 10344–10363. Published online 2023 Sep 13. doi: 10.1093/nar/gkad741
PMCID:
PMC10602925
Abstract Article PDF–1.9M
Unpacking the Complexity of Epithelial Plasticity: From Master Regulator Transcription Factors to Non-Coding RNAs
Charlene Waryah, Eric Alves, Roberta Mazzieri, Riccardo Dolcetti, Erik W. Thompson, Andrew Redfern, Pilar Blancafort
Cancers (Basel) 2023 Jun; 15(12): 3152. Published online 2023 Jun 11. doi: 10.3390/cancers15123152
PMCID:
PMC10326823
Abstract Article PDF–1.9M
TCF3 haploinsufficiency defined by immune, clinical, gene-dosage, and murine studies
Brigette Boast, Shubham Goel, Luis I. González-Granado, Julie Niemela, Jennifer Stoddard, Emily S.J. Edwards, Sandali Seneviratne, Dominik Spensberger, Juan F. Quesada, Luis M. Allende, John McDonnell, Alexandria Haseley, Harry Lesmana, Magdalena A. Walkiewicz, Emad Muhammad, Julian J. Bosco, Thomas A. Fleisher, Shai Cohen, Steven M. Holland, Menno C. van Zelm, Anselm Enders, Hye Sun Kuehn, Sergio D. Rosenzweig
J Allergy Clin Immunol. Author manuscript; available in PMC 2024 Sep 1.
Published in final edited form as: J Allergy Clin Immunol. 2023 Sep; 152(3): 736–747. Published online 2023 Jun 3. doi: 10.1016/j.jaci.2023.05.017
PMCID:
PMC10527523
Abstract Article PDF–1.6M
Identification of TCF3 germline variants in pediatric B-cell acute lymphoblastic leukemia
Carolin Escherich, Wenan Chen, Satoshi Miyamoto, Yui Namikawa, Wenjian Yang, David T. Teachey, Zhenhua Li, Elizabeth A. Raetz, Eric Larsen, Meenakshi Devidas, Paul L. Martin, W. Paul Bowman, Gang Wu, Ching-Hon Pui, Stephen P. Hunger, Mignon L. Loh, Masatoshi Takagi, Jun J. Yang
Blood Adv. 2023 May 23; 7(10): 2177–2180. Published online 2022 Dec 30. doi: 10.1182/bloodadvances.2022008563
PMCID:
PMC10196986
Article PDF–351K
FBXW7β isoform drives transcriptional activation of the proinflammatory TNF cluster in human pro-B cells
Scarlett Y. Yang, Katharina E. Hayer, Hossein Fazelinia, Lynn A. Spruce, Mukta Asnani, Kathryn L. Black, Ammar S. Naqvi, Vinodh Pillai, Yoseph Barash, Kojo S. J. Elenitoba-Johnson, Andrei Thomas-Tikhonenko
Blood Adv. 2023 Apr 11; 7(7): 1077–1091. Published online 2022 Nov 5. doi: 10.1182/bloodadvances.2022007910
PMCID:
PMC10111352
Abstract Article PDF–2.9M
Regulatory programs of B-cell activation and germinal center reaction allow B-ALL escape from CD19 CAR T-cell therapy
Nam Gyu Im, Amy Guillaumet-Adkins, Megha Wal, Anna J. Rogers, Julia Frede, Claire C. Havig, Jing Yang, Praveen Anand, Sarah K. Stegmann, Johannes M. Waldschmidt, Noori Sotudeh, Leili Niu, Jordan Voisine, Michal R. Schweiger, Clemens Grassberger, Jens G. Lohr, Birgit Knoechel
Cancer Immunol Res. Author manuscript; available in PMC 2023 Mar 1.
Published in final edited form as: Cancer Immunol Res. 2022 Sep 1; 10(9): 1055–1068. doi: 10.1158/2326-6066.CIR-21-0626
PMCID:
PMC9444959
Abstract Article PDF–2.2M
Asymmetrical forward and reverse developmental trajectories determine molecular programs of B cell antigen receptor editing
Michael K. Okoreeh, Domenick E. Kennedy, Akinola Olumide Emmanuel, Margaret Veselits, Azam Moshin, Robert H. Ladd, Steven Erickson, Kaitlin C. McLean, Brianna Madrigal, David Nemazee, Mark Maienschein-Cline, Malay Mandal, Marcus R. Clark
Sci Immunol. Author manuscript; available in PMC 2022 Nov 5.
Published in final edited form as: Sci Immunol. 2022 Aug 5; 7(74): eabm1664. Published online 2022 Aug 5. doi: 10.1126/sciimmunol.abm1664
PMCID:
PMC9636592
Abstract Article PDF–2.6M
MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors
Rachel E. Brown, Justin Jacobse, Shruti A. Anant, Koral M. Blunt, Bob Chen, Paige N. Vega, Chase T. Jones, Jennifer M. Pilat, Frank Revetta, Aidan H. Gorby, Kristy R. Stengel, Yash A. Choksi, Kimmo Palin, M. Blanca Piazuelo, Mary Kay Washington, Ken S. Lau, Jeremy A. Goettel, Scott W. Hiebert, Sarah P. Short, Christopher S. Williams
JCI Insight. 2022 May 23; 7(10): e153045. Published online 2022 May 23. doi: 10.1172/jci.insight.153045
PMCID:
PMC9220854
Abstract Article PDF–14M
Helix-Loop-Helix Proteins in Adaptive Immune Development
Megan Aubrey, Zachary J. Warburg, Cornelis Murre
Front Immunol. 2022; 13: 881656. Published online 2022 May 12. doi: 10.3389/fimmu.2022.881656
PMCID:
PMC9134016
Abstract Article PDF–3.0M
Immune Memory in Aging: a Wide Perspective Covering Microbiota, Brain, Metabolism, and Epigenetics
Ozlem Bulut, Gizem Kilic, Jorge Domínguez-Andrés
Clin Rev Allergy Immunol. 2022; 63(3): 499–529. Published online 2021 Dec 15. doi: 10.1007/s12016-021-08905-x
PMCID:
PMC8671603
Abstract Article PDF–1.5M
Bursty gene expression and mRNA decay pathways orchestrate B cell activation
Yi Zhou, Cornelis Murre
Sci Adv. 2021 Dec; 7(49): eabm0819. Published online 2021 Dec 3. doi: 10.1126/sciadv.abm0819
PMCID:
PMC8641932
Abstract Article PDF–4.6M
Identification of clinical molecular targets for childhood Burkitt lymphoma
Jing Zhang, Leijun Meng, Weiyun Jiang, Hong Zhang, Aiwu Zhou, Naiyan Zeng
Transl Oncol. 2020 Dec; 13(12): 100855. Published online 2020 Sep 15. doi: 10.1016/j.tranon.2020.100855
PMCID:
PMC7502376
Abstract Article PDF–4.5M
Burkitt lymphoma-related TCF3 mutations alter TCF3 alternative splicing by disrupting hnRNPH1 binding
Takashi Yamazaki, Lizhi Liu, Erin G. Conlon, James L. Manley
RNA Biol. 2020; 17(10): 1383–1390. Published online 2020 Jun 4. doi: 10.1080/15476286.2020.1772559
PMCID:
PMC7549684
Abstract Article PDF–1.3M
TCF3 mutually exclusive alternative splicing is controlled by long-range cooperative actions between hnRNPH1 and PTBP1
Takashi Yamazaki, Lizhi Liu, James L. Manley
RNA. 2019 Nov; 25(11): 1497–1508. doi: 10.1261/rna.072298.119
PMCID:
PMC6795145
Abstract Article PDF–1.6M
Chromosome dynamics near the sol-gel phase transition dictate the timing of remote genomic interactions
Nimish Khanna, Yaojun Zhang, Joseph S. Lucas, Olga K. Dudko, Cornelis Murre
Nat Commun. 2019; 10: 2771. Published online 2019 Jun 24. doi: 10.1038/s41467-019-10628-9
PMCID:
PMC6591236
Abstract Article PDF–3.4M
The Concerted Action of E2-2 and HEB Is Critical for Early Lymphoid Specification
Thibault Bouderlique, Lucia Peña-Pérez, Shabnam Kharazi, Miriam Hils, Xiaoze Li, Aleksandra Krstic, Ayla De Paepe, Christian Schachtrup, Charlotte Gustafsson, Dan Holmberg, Kristina Schachtrup, Robert Månsson
Front Immunol. 2019; 10: 455. Published online 2019 Mar 18. doi: 10.3389/fimmu.2019.00455
PMCID:
PMC6433000
Abstract Article PDF–11M
E47 modulates hepatic glucocorticoid action
M. Charlotte Hemmer, Michael Wierer, Kristina Schachtrup, Michael Downes, Norbert Hübner, Ronald M. Evans, N. Henriette Uhlenhaut
Nat Commun. 2019; 10: 306. Published online 2019 Jan 18. doi: 10.1038/s41467-018-08196-5
PMCID:
PMC6338785
Abstract Article PDF–1.5M
Helix–loop–helix proteins and the advent of cellular diversity: 30 years of discovery
Cornelis Murre
Genes Dev. 2019 Jan 1; 33(1-2): 6–25. doi: 10.1101/gad.320663.118
PMCID:
PMC6317319
Abstract Article PDF–3.1M
BRWD1 orchestrates epigenetic landscape of late B lymphopoiesis
Malay Mandal, Mark Maienschein-Cline, Patrick Maffucci, Margaret Veselits, Domenick E. Kennedy, Kaitlin C. McLean, Michael K. Okoreeh, Sophiya Karki, Charlotte Cunningham-Rundles, Marcus R. Clark
Nat Commun. 2018; 9: 3888. Published online 2018 Sep 24. doi: 10.1038/s41467-018-06165-6
PMCID:
PMC6155124
Abstract Article PDF–3.9M
TCF3 alternative splicing controlled by hnRNP H/F regulates E-cadherin expression and hESC pluripotency
Takashi Yamazaki, Lizhi Liu, Denis Lazarev, Amr Al-Zain, Vitalay Fomin, Percy Luk Yeung, Stuart M. Chambers, Chi-Wei Lu, Lorenz Studer, James L. Manley
Genes Dev. 2018 Sep 1; 32(17-18): 1161–1174. doi: 10.1101/gad.316984.118
Correction in:
Genes Dev. 2019 Jun 1; 33(11-12): 733–736.
PMCID:
PMC6120717
Abstract Article PDF–1.8M
Inhibitor of DNA Binding 2 Inhibits Epithelial-Mesenchymal Transition via Up-Regulation of Notch3 in Breast Cancer
Xiao-Fen Wen, Min Chen, Yang Wu, Min-Na Chen, Aleksandra Glogowska, Thomas Klonisch, Guo-Jun Zhang
Transl Oncol. 2018 Oct; 11(5): 1259–1270. Published online 2018 Aug 14. doi: 10.1016/j.tranon.2018.07.015
PMCID:
PMC6097462
Abstract Article PDF–770K
Epigenetic silencing of miR-125b is required for normal B-cell development
Guideng Li, Alex Yick-Lun So, Reeshelle Sookram, Stephanie Wong, Jessica K. Wang, Yong Ouyang, Peng He, Yapeng Su, Rafael Casellas, David Baltimore
Blood. 2018 Apr 26; 131(17): 1920–1930. Prepublished online 2018 Mar 19. doi: 10.1182/blood-2018-01-824540
PMCID:
PMC5921965
Abstract Article
Mycobacteria exploit nitric oxide‐induced transformation of macrophages into permissive giant cells
Kourosh Gharun, Julia Senges, Maximilian Seidl, Anne Lösslein, Julia Kolter, Florens Lohrmann, Manfred Fliegauf, Magdeldin Elgizouli, Martina Vavra, Kristina Schachtrup, Anna L Illert, Martine Gilleron, Carsten J Kirschning, Antigoni Triantafyllopoulou, Philipp Henneke
EMBO Rep. 2017 Dec; 18(12): 2144–2159. Published online 2017 Nov 2. doi: 10.15252/embr.201744121
Correction in:
EMBO Rep. 2018 Dec; 19(12): e47190.
PMCID:
PMC5709734
Abstract Article PDF–1.3M
Evidence for Ig Light Chain Isotype Exclusion in Shark B Lymphocytes Suggests Ordered Mechanisms
Anna Iacoangeli, Anita Lui, Ashley Haines, Yuko Ohta, Martin Flajnik, Ellen Hsu
J Immunol. 2017 Sep 1; 199(5): 1875–1885. Published online 2017 Jul 31. doi: 10.4049/jimmunol.1700762
PMCID:
PMC5563170
Abstract Article PDF–2.0M
Relevance of ID3-TCF3-CCND3 pathway mutations in pediatric aggressive B-cell lymphoma treated according to the non-Hodgkin Lymphoma Berlin-Frankfurt-Münster protocols
Marius Rohde, Bettina R. Bonn, Martin Zimmermann, Jonas Lange, Anja Möricke, Wolfram Klapper, Ilske Oschlies, Monika Szczepanowski, Inga Nagel, Martin Schrappe, MMML-MYC-SYS Project, ICGC MMML-Seq Project, Markus Loeffler, Reiner Siebert, Alfred Reiter, Birgit Burkhardt
Haematologica. 2017 Jun; 102(6): 1091–1098. doi: 10.3324/haematol.2016.156885
PMCID:
PMC5451341
Abstract Article PDF–1.4M
Mechanisms of central tolerance for B cells
David Nemazee
Nat Rev Immunol. Author manuscript; available in PMC 2017 Oct 1.
Published in final edited form as: Nat Rev Immunol. 2017 May; 17(5): 281–294. Published online 2017 Apr 3. doi: 10.1038/nri.2017.19
PMCID:
PMC5623591
Abstract Article PDF–1.0M