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Cortical and Subcortical Cerebrovascular Resistance Index in Mild Cognitive Impairment and Alzheimer's Disease
Daniel A. Nation, Christina E. Wierenga, Lindsay R. Clark, Sheena I. Dev, Nikki H. Stricker, Amy J. Jak, David P. Salmon, Lisa Delano-Wood, Katherine J. Bangen, Robert A. Rissman, Thomas T. Liu, Mark W. Bondi
J Alzheimers Dis. Author manuscript; available in PMC 2014 Jul 9.
Published in final edited form as: J Alzheimers Dis. 2013; 36(4): 689–698. doi: 10.3233/JAD-130086
PMCID:
PMC4089500
Abstract Article PDF–668K

Is Cited by the Following 30 Articles in this Archive:

Establishing the distribution of cerebrovascular resistance using computational fluid dynamics and 4D flow MRI
Axel Vikström, Petter Holmlund, Madelene Holmgren, Anders Wåhlin, Laleh Zarrinkoob, Jan Malm, Anders Eklund
Sci Rep. 2024; 14: 14585. Published online 2024 Jun 25. doi: 10.1038/s41598-024-65431-4
PMCID:
PMC11199643
Abstract Article PDF–2.5M
Spontaneous cerebrovascular reactivity at rest in older adults with and without mild cognitive impairment and memory deficits
Allison C Engstrom, John Paul Alitin, Arunima Kapoor, Shubir Dutt, Trevor Lohman, Isabel J Sible, Anisa J Marshall, Fatemah Shenasa, Aimée Gaubert, Farrah Ferrer, Amy Nguyen, David Robert Bradford, Kathleen Rodgers, Lorena Sordo, Elizabeth Head, Xingfeng Shao, Danny JJ Wang, Daniel A Nation
Version 1. medRxiv. Preprint. 2024 Jun 19. doi: 10.1101/2024.06.18.24309109
PMCID:
PMC11213117
Abstract Article PDF–441K
Blockage of VEGF function by bevacizumab alleviates early-stage cerebrovascular dysfunction and improves cognitive function in a mouse model of Alzheimer’s disease
Min Zhang, Zhan Zhang, Honghong Li, Yuting Xia, Mengdan Xing, Chuan Xiao, Wenbao Cai, Lulu Bu, Yi Li, Tae-Eun Park, Yamei Tang, Xiaojing Ye, Wei-Jye Lin
Transl Neurodegener. 2024; 13: 1. Published online 2024 Jan 3. doi: 10.1186/s40035-023-00388-4
PMCID:
PMC10763201
Abstract Article PDF–6.0M
New evidence for fractional pressure ratio prediction by pulsatility index from transcranial Doppler in patients with symptomatic cerebrovascular stenosis disease
Xiaotong Xu, Raynald, Xian Li, Ruichen Li, Hongchao Yang, Xi Zhao, Zhongrong Miao, Dapeng Mo
Quant Imaging Med Surg. 2024 Jan 3; 14(1): 264–272. Published online 2023 Nov 7. doi: 10.21037/qims-23-701
PMCID:
PMC10784021
Abstract Article PDF–355K
Cerebrovascular Pulsatility Index Is Reduced in Autosomal Dominant Polycystic Kidney Disease
Cortney N. Steele, Ester S. Oh, Wei Wang, Heather Farmer-Bailey, Berenice Gitomer, Michel Chonchol, Kristen L. Nowak
Am J Nephrol. 2023 Sep; 54(5-6): 165–174. Published online 2023 May 16. doi: 10.1159/000530583
PMCID:
PMC10529076
Abstract Article
The impact of a high-sodium diet regimen on cerebrovascular morphology and cerebral perfusion in Alzheimer's disease
Jin Yu, Hong Zhu, Mark S. Kindy, Saeid Taheri
Cereb Circ Cogn Behav. 2023; 4: 100161. Published online 2023 Jan 29. doi: 10.1016/j.cccb.2023.100161
PMCID:
PMC9895990
Abstract Article PDF–9.8M
Older adults with perivascular spaces exhibit cerebrovascular reactivity deficits
Arunima Kapoor, Belinda Yew, Jung Yun Jang, Shubir Dutt, Yanrong Li, John Paul M. Alitin, Aimee Gaubert, Jean K Ho, Anna E. Blanken, Isabel J Sible, Anisa Marshall, Xingfeng Shao, Mara Mather, Danny J J Wang, Daniel A Nation
Neuroimage. Author manuscript; available in PMC 2023 Mar 23.
Published in final edited form as: Neuroimage. 2022 Dec 1; 264: 119746. Published online 2022 Nov 9. doi: 10.1016/j.neuroimage.2022.119746
PMCID:
PMC10033456
Abstract Article PDF–1.1M
Mediation of the APOE Associations With Cognition Through Cerebral Blood Flow: The CIBL Study
Yan-Li Wang, Mengfan Sun, Fang-Ze Wang, Xiaohong Wang, Ziyan Jia, Yuan Zhang, Runzhi Li, Jiwei Jiang, Linlin Wang, Wenyi Li, Yongan Sun, Jinglong Chen, Cuicui Zhang, Baolin Shi, Jianjian Liu, Xiangrong Liu, Jun Xu
Front Aging Neurosci. 2022; 14: 928925. Published online 2022 Jun 30. doi: 10.3389/fnagi.2022.928925
PMCID:
PMC9279129
Abstract Article PDF–781K
Potential Mechanisms Underlying Resistance to Dementia in Non-Demented Individuals with Alzheimer’s Disease Neuropathology
Frédérique K. Kok, Suzanne L. van Leerdam, Elizabeth C.M. de Lange
J Alzheimers Dis. 2022; 87(1): 51–81. Prepublished online 2022 Mar 7. Published online 2022 May 3. doi: 10.3233/JAD-210607
PMCID:
PMC9198800
Abstract Article PDF–1.3M
Cerebrovascular reactivity deficits in cognitively unimpaired older adults: vasodilatory versus vasoconstrictive responses
Belinda Yew, Jung Yun Jang, Shubir Dutt, Yanrong Li, Isabel J. Sible, Aimée Gaubert, Jean K. Ho, Anna E. Blanken, Anisa Marshall, Xingfeng Shao, Danny J. J. Wang, Daniel A. Nation
Neurobiol Aging. Author manuscript; available in PMC 2024 Mar 22.
Published in final edited form as: Neurobiol Aging. 2022 May; 113: 55–62. Published online 2022 Feb 23. doi: 10.1016/j.neurobiolaging.2022.02.006
PMCID:
PMC10958374
Abstract Article PDF–1.0M
VEGF signalling causes stalls in brain capillaries and reduces cerebral blood flow in Alzheimer’s mice
Muhammad Ali, Kaja Falkenhain, Brendah N Njiru, Muhammad Murtaza-Ali, Nancy E Ruiz-Uribe, Mohammad Haft-Javaherian, Stall Catchers, Nozomi Nishimura, Chris B Schaffer, Oliver Bracko
Brain. 2022 Apr; 145(4): 1449–1463. Published online 2022 Jan 20. doi: 10.1093/brain/awab387
PMCID:
PMC9150081
Abstract Article PDF–1.7M
Arterial stiffening acts synergistically with APOE genotype and AD biomarker status to influence memory in older adults without dementia
Katherine J. Bangen, Denis S. Smirnov, Lisa Delano-Wood, Christina E. Wierenga, Mark W. Bondi, David P. Salmon, Douglas Galasko
Alzheimers Res Ther. 2021; 13: 121. Published online 2021 Jul 1. doi: 10.1186/s13195-021-00851-2
PMCID:
PMC8246656
Abstract Article PDF–948K
Evidence of cerebral hemodynamic dysregulation in middle-aged APOE ε4 carriers: The PREVENT-Dementia study
Maria-Eleni Dounavi, Audrey Low, Elizabeth F McKiernan, Elijah Mak, Graciela Muniz-Terrera, Karen Ritchie, Craig W Ritchie, Li Su, John T. O’Brien
J Cereb Blood Flow Metab. 2021 Nov; 41(11): 2844–2855. Published online 2021 Jun 2. doi: 10.1177/0271678X211020863
PMCID:
PMC8543665
Abstract Article PDF–483K
Type 2 Diabetes Mellitus May Exacerbate Gray Matter Atrophy in Patients With Early-Onset Mild Cognitive Impairment
Chang Li, Zhiwei Zuo, Daihong Liu, Rui Jiang, Yang Li, Haitao Li, Xuntao Yin, Yuqi Lai, Jian Wang, Kunlin Xiong
Front Neurosci. 2020; 14: 856. Published online 2020 Aug 11. doi: 10.3389/fnins.2020.00856
PMCID:
PMC7432296
Abstract Article PDF–3.1M
Hypertension and Alzheimer’s disease: indirect effects through circle of Willis atherosclerosis
Graham M L Eglit, Alexandra J Weigand, Daniel A Nation, Mark W Bondi, Katherine J Bangen
Brain Commun. 2020; 2(2): fcaa114. Published online 2020 Jul 21. doi: 10.1093/braincomms/fcaa114
PMCID:
PMC7846096
Abstract Article PDF–298K
Zibotentan, an Endothelin A Receptor Antagonist, Prevents Amyloid-β-Induced Hypertension and Maintains Cerebral Perfusion
Jennifer C. Palmer, Hannah M. Tayler, Laurence Dyer, Patrick G. Kehoe, Julian F.R. Paton, Seth Love
J Alzheimers Dis. 2020; 73(3): 1185–1199. Prepublished online 2020 Jan 2. Published online 2020 Feb 4. doi: 10.3233/JAD-190630
PMCID:
PMC7081103
Abstract Article PDF–299K
Increasing cerebral blood flow improves cognition into late stages in Alzheimer’s disease mice
Oliver Bracko, Brendah N Njiru, Madisen Swallow, Muhammad Ali, Mohammad Haft-Javaherian, Chris B Schaffer
J Cereb Blood Flow Metab. 2020 Jul; 40(7): 1441–1452. Published online 2019 Sep 7. doi: 10.1177/0271678X19873658
PMCID:
PMC7308509
Abstract Article PDF–1.3M
Vascular dysfunction – the disregarded partner of Alzheimer’s disease
Melanie D. Sweeney, Axel Montagne, Abhay P. Sagare, Daniel A. Nation, Lon S. Schneider, Helena C. Chui, Michael G. Harrington, Judy Pa, Meng Law, Danny J. J. Wang, Russell E. Jacobs, Fergus N. Doubal, Joel Ramirez, Sandra E. Black, Maiken Nedergaard, Helene Benveniste, Martin Dichgans, Costantino Iadecola, Seth Love, Philip M. Bath, Hugh S. Markus, Rustam A. Salman, Stuart M. Allan, Terence J. Quinn, Rajesh N. Kalaria, David J. Werring, Roxana O. Carare, Rhian M. Touyz, Steve C. R. Williams, Michael A. Moskowitz, Zvonimir S. Katusic, Sarah E. Lutz, Orly Lazarov, Richard D. Minshall, Jalees Rehman, Thomas P. Davis, Cheryl L. Wellington, Hector M. Gonzalez, Chun Yuan, Samuel N. Lockhart, Timothy M. Hughes, Christopher L. H. Chen, Perminder Sachdev, John T. O’Brien, Ingmar Skoog, Leonardo Pantoni, Deborah R. Gustafson, Geert Jan Biessels, Anders Wallin, Eric E. Smith, Vincent Mok, Adrian Wong, Peter Passmore, Frederick Barkof, Majon Muller, Monique M. B. Breteler, Gustavo C. Roman, Edith Hamel, Sudha Seshadri, Rebecca F. Gottesman, Mark A. van Buchem, Zoe Arvanitakis, Julie A. Schneider, Lester R. Drewes, Vladimir Hachinski, Caleb E. Finch, Arthur W. Toga, Joanna M. Wardlaw, Berislav V. Zlokovic
Alzheimers Dement. Author manuscript; available in PMC 2020 Jan 1.
Published in final edited form as: Alzheimers Dement. 2019 Jan; 15(1): 158–167. doi: 10.1016/j.jalz.2018.07.222
PMCID:
PMC6338083
Article PDF–482K
The role of brain vasculature in neurodegenerative disorders
Melanie D. Sweeney, Kassandra Kisler, Axel Montagne, Arthur W. Toga, Berislav V. Zlokovic
Nat Neurosci. Author manuscript; available in PMC 2019 Apr 1.
Published in final edited form as: Nat Neurosci. 2018 Oct; 21(10): 1318–1331. Published online 2018 Sep 24. doi: 10.1038/s41593-018-0234-x
PMCID:
PMC6198802
Abstract Article PDF–998K
Reduced Regional Cerebral Blood Flow Relates to Poorer Cognition in Older Adults With Type 2 Diabetes
Katherine J. Bangen, Madeleine L. Werhane, Alexandra J. Weigand, Emily C. Edmonds, Lisa Delano-Wood, Kelsey R. Thomas, Daniel A. Nation, Nicole D. Evangelista, Alexandra L. Clark, Thomas T. Liu, Mark W. Bondi
Front Aging Neurosci. 2018; 10: 270. Published online 2018 Sep 10. doi: 10.3389/fnagi.2018.00270
PMCID:
PMC6139361
Abstract Article PDF–1.1M
APOE genotype modifies the association between central arterial stiffening and cognition in older adults
Francis E. Cambronero, Dandan Liu, Jacquelyn E. Neal, Elizabeth E. Moore, Katherine A. Gifford, James G. Terry, Sangeeta Nair, Kimberly R. Pechman, Katie E. Osborn, Timothy J. Hohman, Susan P. Bell, J. David Sweatt, Thomas J. Wang, Joshua A. Beckman, John Jeffrey Carr, Angela L. Jefferson
Neurobiol Aging. Author manuscript; available in PMC 2019 Jul 1.
Published in final edited form as: Neurobiol Aging. 2018 Jul; 67: 120–127. Published online 2018 Feb 20. doi: 10.1016/j.neurobiolaging.2018.02.009
PMCID:
PMC5985659
Abstract Article PDF–590K
Cerebrovascular resistance: effects on cognitive decline, cortical atrophy, and progression to dementia
Belinda Yew, Daniel A. Nation, for the Alzheimer’s Disease Neuroimaging Initiative
Brain. 2017 Jul; 140(7): 1987–2001. Published online 2017 Jun 1. doi: 10.1093/brain/awx112
PMCID:
PMC6059092
Abstract Article PDF–722K
Macrovascular and microvascular cerebral blood flow in adults at risk for Alzheimer's disease
Lindsay R. Clark, Sara E. Berman, Leonardo A. Rivera-Rivera, Siobhan M. Hoscheidt, Burcu F. Darst, Corinne D. Engelman, Howard A. Rowley, Cynthia M. Carlsson, Sanjay Asthana, Patrick Turski, Oliver Wieben, Sterling C. Johnson
Alzheimers Dement (Amst) 2017; 7: 48–55. Published online 2017 Jan 23. doi: 10.1016/j.dadm.2017.01.002
PMCID:
PMC5318539
Abstract Article PDF–1.4M
Cerebral Hypoperfusion and the Energy Deficit in Alzheimer's Disease
Seth Love, J.Scott Miners
Brain Pathol. 2016 Sep; 26(5): 607–617. Published online 2016 Sep 26. doi: 10.1111/bpa.12401
PMCID:
PMC8028913
Abstract Article PDF–377K
Brain imaging of neurovascular dysfunction in Alzheimer’s disease
Axel Montagne, Daniel A. Nation, Judy Pa, Melanie D. Sweeney, Arthur W. Toga, Berislav V. Zlokovic
Acta Neuropathol. Author manuscript; available in PMC 2017 May 1.
Published in final edited form as: Acta Neuropathol. 2016 May; 131(5): 687–707. Published online 2016 Apr 1. doi: 10.1007/s00401-016-1570-0
PMCID:
PMC5283382
Abstract Article PDF–1.3M
The Utility of Cerebral Blood Flow as a Biomarker of Preclinical Alzheimer’s Disease
Chelsea C. Hays, Zvinka Z. Zlatar, Christina E. Wierenga
Cell Mol Neurobiol. Author manuscript; available in PMC 2017 Jan 30.
Published in final edited form as: Cell Mol Neurobiol. 2016 Mar; 36(2): 167–179. Published online 2016 Feb 22. doi: 10.1007/s10571-015-0261-z
PMCID:
PMC5278904
Abstract Article PDF–1.2M
Cerebrovascular disease in ageing and Alzheimer’s disease
Seth Love, J. Scott Miners
Acta Neuropathol. 2016; 131: 645–658. Published online 2015 Dec 28. doi: 10.1007/s00401-015-1522-0
PMCID:
PMC4835514
Abstract Article PDF–1.8M
The major cerebral arteries proximal to the Circle of Willis contribute to cerebrovascular resistance in humans
Esther AH Warnert, Emma C Hart, Judith E Hall, Kevin Murphy, Richard G Wise
J Cereb Blood Flow Metab. 2016 Aug; 36(8): 1384–1395. Published online 2015 Nov 20. doi: 10.1177/0271678X15617952
PMCID:
PMC4976750
Abstract Article PDF–436K
Pulse Pressure in Relation to Tau-Mediated Neurodegeneration, Cerebral Amyloidosis, and Progression to Dementia in Very Old Adults
Daniel A. Nation, Emily C. Edmonds, Katherine J. Bangen, Lisa Delano-Wood, Blake K. Scanlon, S. Duke Han, Steven D. Edland, David P. Salmon, Douglas R. Galasko, Mark W. Bondi, for the Alzheimer’s Disease Neuroimaging Initiative Investigators
JAMA Neurol. Author manuscript; available in PMC 2015 May 12.
Published in final edited form as: JAMA Neurol. 2015 May 1; 72(5): 546–553. doi: 10.1001/jamaneurol.2014.4477
PMCID:
PMC4428938
Abstract Article PDF–717K
Elevated cerebrovascular resistance index is associated with cognitive dysfunction in the very-old
Lindsay R Clark, Daniel A Nation, Christina E Wierenga, Katherine J Bangen, Sheena I Dev, David D Shin, Lisa Delano-Wood, Thomas T Liu, Robert A Rissman, Mark W Bondi
Alzheimers Res Ther. 2015; 7: 3. Published online 2015 Jan 21. doi: 10.1186/s13195-014-0080-3
PMCID:
PMC4942967
Abstract Article PDF–1002K