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Sphingosine 1-phosphate receptor 3 and RhoA signaling mediate inflammatory gene expression in astrocytes
Stephanie S. Dusaban, Jerold Chun, Hugh Rosen, Nicole H. Purcell, Joan Heller Brown
J Neuroinflammation. 2017; 14: 111. Published online 2017 Jun 2. doi: 10.1186/s12974-017-0882-x
PMCID:
PMC5455202
Abstract Article PDF–1.0M

Is Cited by the Following 59 Articles in this Archive:

Lysophospholipid receptors in neurodegeneration and neuroprotection
Eric Birgbauer
Explor Neuroprotective Ther. Author manuscript; available in PMC 2024 Sep 6.
Published in final edited form as: Explor Neuroprotective Ther. 2024; 4(4): 349–365. Published online 2024 Aug 22. doi: 10.37349/ent.2024.00088
PMCID:
PMC11379401
Abstract Article PDF–414K
Inhibition of Sphingosine Kinase 1 Reduces Sphingosine-1-Phosphate and Exacerbates Amyloid-Beta-Induced Neuronal Cell Death in Mixed-Glial-Cell Culture
Tomoki Minamihata, Katsura Takano-Kawabe, Mitsuaki Moriyama
Neurol Int. 2024 Aug; 16(4): 709–730. Published online 2024 Jul 4. doi: 10.3390/neurolint16040054
PMCID:
PMC11270188
Abstract Article PDF–4.3M
Spatiotemporal sphingosine-1-phosphate receptor 3 expression within the cerebral vasculature after ischemic stroke
Hana Matuskova, Lisa T. Porschen, Frank Matthes, Arne G. Lindgren, Gabor C. Petzold, Anja Meissner
iScience. 2024 Jun 21; 27(6): 110031. Published online 2024 May 20. doi: 10.1016/j.isci.2024.110031
PMCID:
PMC11167442
Abstract Article PDF–4.9M
Dysregulation of sphingolipid metabolism in pain
Jianfeng Wang, Guangda Zheng, Linfeng Wang, Linghan Meng, Juanxia Ren, Lu Shang, Dongtao Li, Yanju Bao
Front Pharmacol. 2024; 15: 1337150. Published online 2024 Mar 8. doi: 10.3389/fphar.2024.1337150
PMCID:
PMC10957601
Abstract Article PDF–1.8M
Nuclear SphK2/S1P signaling is a key regulator of ApoE production and Aβ uptake in astrocytes
Masato Komai, Yuka Noda, Atsuya Ikeda, Nanaka Kaneshiro, Yuji Kamikubo, Takashi Sakurai, Takashi Uehara, Nobumasa Takasugi
J Lipid Res. 2024 Mar; 65(3): 100510. Published online 2024 Jan 26. doi: 10.1016/j.jlr.2024.100510
PMCID:
PMC10907773
Abstract Article PDF–2.9M
Human motor neurons derived from induced pluripotent stem cells are susceptible to SARS-CoV-2 infection
Gioia Cappelletti, Claudia Colombrita, Fiona Limanaqi, Sabrina Invernizzi, Micaela Garziano, Claudia Vanetti, Claudia Moscheni, Serena Santangelo, Silvia Zecchini, Daria Trabattoni, Vincenzo Silani, Mario Clerici, Antonia Ratti, Mara Biasin
Front Cell Neurosci. 2023; 17: 1285836. Published online 2023 Dec 5. doi: 10.3389/fncel.2023.1285836
PMCID:
PMC10728732
Abstract Article PDF–2.3M
Density of Sphingosine-1-Phosphate Receptors Is Altered in Cortical Nerve-Terminals of Insulin-Resistant Goto-Kakizaki Rats and Diet-Induced Obese Mice
Cecilia Skoug, Hüseyin Erdogan, Lotte Vanherle, João P. P. Vieira, Frank Matthes, Lena Eliasson, Anja Meissner, João M. N. Duarte
Neurochem Res. 2024; 49(2): 338–347. Published online 2023 Oct 4. doi: 10.1007/s11064-023-04033-4
PMCID:
PMC10787890
Abstract Article PDF–1.1M
Therapeutic Plasma Exchange and Multiple Sclerosis Dysregulations: Focus on the Removal of Pathogenic Circulatory Factors and Altering Nerve Growth Factor and Sphingosine-1-Phosphate Plasma Levels
Dimitar Tonev, Albena Momchilova
Curr Issues Mol Biol. 2023 Oct; 45(10): 7749–7774. Published online 2023 Sep 25. doi: 10.3390/cimb45100489
PMCID:
PMC10605592
Abstract Article PDF–7.2M
Immune System and Brain/Intestinal Barrier Functions in Psychiatric Diseases: Is Sphingosine-1-Phosphate at the Helm?
David Martín-Hernández, Marina Muñoz-López, Hiram Tendilla-Beltrán, Javier R. Caso, Borja García-Bueno, Luis Menchén, Juan C. Leza
Int J Mol Sci. 2023 Aug; 24(16): 12634. Published online 2023 Aug 10. doi: 10.3390/ijms241612634
PMCID:
PMC10454107
Abstract Article PDF–2.2M
S1P Lyase Deficiency in the Brain Promotes Astrogliosis and NLRP3 Inflammasome Activation via Purinergic Signaling
Shah Alam, Sumaiya Yasmeen Afsar, Maya Anik Wolter, Luisa Michelle Volk, Daniel Nicolae Mitroi, Dagmar Meyer zu Heringdorf, Gerhild van Echten-Deckert
Cells. 2023 Jul; 12(14): 1844. Published online 2023 Jul 13. doi: 10.3390/cells12141844
PMCID:
PMC10378183
Abstract Article PDF–3.5M
Central Versus Peripheral Drug Exposure Ratio, a Key Differentiator for Siponimod Over Fingolimod?
Marc Bigaud, Pamela Ramseier, Sarah Tisserand, Meike Lang, Beatrice Urban, Christian Beerli, Göril Karlsson
Neurol Ther. 2023 Aug; 12(4): 1187–1203. Published online 2023 May 17. doi: 10.1007/s40120-023-00487-4
PMCID:
PMC10310674
Abstract Article PDF–1.5M
Molecular and neuroimmune pharmacology of S1P receptor modulators and other disease-modifying therapies for multiple sclerosis
Yasuyuki Kihara, Jerold Chun
Pharmacol Ther. Author manuscript; available in PMC 2024 Feb 12.
Published in final edited form as: Pharmacol Ther. 2023 Jun; 246: 108432. Published online 2023 May 4. doi: 10.1016/j.pharmthera.2023.108432
PMCID:
PMC10860660
Abstract Article PDF–1.6M
Epigenetic Regulation Mediated by Sphingolipids in Cancer
Nicolò Bozzini, Sofia Avnet, Nicola Baldini, Margherita Cortini
Int J Mol Sci. 2023 Mar; 24(6): 5294. Published online 2023 Mar 10. doi: 10.3390/ijms24065294
PMCID:
PMC10048860
Abstract Article PDF–1.7M
Time- and Sex-Dependent Effects of Fingolimod Treatment in a Mouse Model of Alzheimer’s Disease
Pablo Bascuñana, Mirjam Brackhan, Luisa Möhle, Jingyun Wu, Thomas Brüning, Ivan Eiriz, Baiba Jansone, Jens Pahnke
Biomolecules. 2023 Feb; 13(2): 331. Published online 2023 Feb 9. doi: 10.3390/biom13020331
PMCID:
PMC9953119
Abstract Article PDF–4.2M
Sphingosine-1-phosphate Signalling in Aneurysmal Subarachnoid Haemorrhage: Basic Science to Clinical Translation
Ben Gaastra, John Zhang, Will Tapper, Diederik Bulters, Ian Galea
Transl Stroke Res. 2024; 15(2): 352–363. Published online 2023 Feb 7. doi: 10.1007/s12975-023-01133-9
PMCID:
PMC10891271
Abstract Article PDF–1.2M
Signal Transduction and Gene Regulation in the Endothelium
Michel V. Levesque, Timothy Hla
Cold Spring Harb Perspect Med. 2023 Jan; 13(1): a041153. doi: 10.1101/cshperspect.a041153
PMCID:
PMC9722983
Currently embargoed: Free in PMC on Jan 1, 2025; PubMed
Differential Enantiomer-Specific Signaling of Cannabidiol at CB1 Receptors
Taryn Bosquez-Berger, Sierra Wilson, Christos Iliopoulos-Tsoutsouvas, Shan Jiang, Jim Wager-Miller, Spyros P. Nikas, Ken P. Mackie, Alexandros Makriyannis, Alex Straiker
Mol Pharmacol. 2022 Dec; 102(6): 259–268. Published online 2022 Dec. doi: 10.1124/molpharm.121.000305
PMCID:
PMC11033957
Abstract Article PDF–1.9M
Ceramide/Sphingosine 1-Phosphate Axis as a Key Target for Diagnosis and Treatment in Alzheimer’s Disease and Other Neurodegenerative Diseases
Antía Custodia, Daniel Romaus-Sanjurjo, Marta Aramburu-Núñez, Diego Álvarez-Rafael, Laura Vázquez-Vázquez, Javier Camino-Castiñeiras, Yago Leira, Juan Manuel Pías-Peleteiro, José Manuel Aldrey, Tomás Sobrino, Alberto Ouro
Int J Mol Sci. 2022 Aug; 23(15): 8082. Published online 2022 Jul 22. doi: 10.3390/ijms23158082
PMCID:
PMC9331765
Abstract Article PDF–1.2M
Sphingosine 1-Phoshpate Receptors are Located in Synapses and Control Spontaneous Activity of Mouse Neurons in Culture
Cecilia Skoug, Isak Martinsson, Gunnar K. Gouras, Anja Meissner, João M. N. Duarte
Neurochem Res. 2022; 47(10): 3114–3125. Published online 2022 Jul 4. doi: 10.1007/s11064-022-03664-3
PMCID:
PMC9470655
Abstract Article PDF–3.7M
The Role of Immunosenescence in Cerebral Small Vessel Disease: A Review
Alessandro Del Cuore, Gaetano Pacinella, Renata Riolo, Antonino Tuttolomondo
Int J Mol Sci. 2022 Jul; 23(13): 7136. Published online 2022 Jun 27. doi: 10.3390/ijms23137136
PMCID:
PMC9266569
Abstract Article PDF–1.2M
Gα12 and Gα13: Versatility in Physiology and Pathology
Paipai Guo, Yu Tai, Manman Wang, Hanfei Sun, Lingling Zhang, Wei Wei, Yang K. Xiang, Qingtong Wang
Front Cell Dev Biol. 2022; 10: 809425. Published online 2022 Feb 14. doi: 10.3389/fcell.2022.809425
PMCID:
PMC8883321
Abstract Article PDF–1.5M
Sphingosine-1-Phosphate Signaling in Ischemic Stroke: From Bench to Bedside and Beyond
Shuo-Qi Zhang, Jun Xiao, Man Chen, Luo-Qi Zhou, Ke Shang, Chuan Qin, Dai-Shi Tian
Front Cell Neurosci. 2021; 15: 781098. Published online 2021 Nov 30. doi: 10.3389/fncel.2021.781098
PMCID:
PMC8669352
Abstract Article PDF–735K
Modulation of the Blood–Brain Barrier for Drug Delivery to Brain
Liang Han
Pharmaceutics. 2021 Dec; 13(12): 2024. Published online 2021 Nov 27. doi: 10.3390/pharmaceutics13122024
PMCID:
PMC8708282
Abstract Article PDF–1.4M
Blood-Brain Barrier Dysfunction Amplifies the Development of Neuroinflammation: Understanding of Cellular Events in Brain Microvascular Endothelial Cells for Prevention and Treatment of BBB Dysfunction
Fuyuko Takata, Shinsuke Nakagawa, Junichi Matsumoto, Shinya Dohgu
Front Cell Neurosci. 2021; 15: 661838. Published online 2021 Sep 13. doi: 10.3389/fncel.2021.661838
PMCID:
PMC8475767
Abstract Article PDF–2.7M
Critical Roles of Lysophospholipid Receptors in Activation of Neuroglia and Their Neuroinflammatory Responses
Bhakta Prasad Gaire, Ji-Woong Choi
Int J Mol Sci. 2021 Aug; 22(15): 7864. Published online 2021 Jul 23. doi: 10.3390/ijms22157864
PMCID:
PMC8346064
Abstract Article PDF–929K
The Role of Fatty Acids in Ceramide Pathways and Their Influence on Hypothalamic Regulation of Energy Balance: A Systematic Review
Andressa Reginato, Alana Carolina Costa Veras, Mayara da Nóbrega Baqueiro, Carolina Panzarin, Beatriz Piatezzi Siqueira, Marciane Milanski, Patrícia Cristina Lisboa, Adriana Souza Torsoni
Int J Mol Sci. 2021 May; 22(10): 5357. Published online 2021 May 19. doi: 10.3390/ijms22105357
PMCID:
PMC8160791
Abstract Article PDF–3.4M
Central Acting Hsp10 Regulates Mitochondrial Function, Fatty Acid Metabolism, and Insulin Sensitivity in the Hypothalamus
Kristina Wardelmann, Michaela Rath, José Pedro Castro, Sabine Blümel, Mareike Schell, Robert Hauffe, Fabian Schumacher, Tanina Flore, Katrin Ritter, Andreas Wernitz, Toru Hosoi, Koichiro Ozawa, Burkhard Kleuser, Jürgen Weiß, Annette Schürmann, André Kleinridders
Antioxidants (Basel) 2021 May; 10(5): 711. Published online 2021 Apr 30. doi: 10.3390/antiox10050711
PMCID:
PMC8145035
Abstract Article PDF–3.5M
Krankheitsmodifizierende Therapie der sekundär progredienten Multiplen Sklerose
Olaf Hoffmann, Ralf Gold
Nervenarzt. 2021; 92(10): 1052–1060. German. Published online 2021 Mar 3. doi: 10.1007/s00115-021-01080-6
PMCID:
PMC8484088
Abstract Article PDF–386K
Critical roles of sphingosine kinase 1 in the regulation of neuroinflammation and neuronal injury after spinal cord injury
Chenjian Wang, Tianzhen Xu, Brittany Bolduc Lachance, Xiqiang Zhong, Guangjie Shen, Tao Xu, Chengxuan Tang, Xiaofeng Jia
J Neuroinflammation. 2021; 18: 50. Published online 2021 Feb 18. doi: 10.1186/s12974-021-02092-4
PMCID:
PMC7893778
Abstract Article PDF–11M
Astrocytes: a double-edged sword in neurodegenerative diseases
Zhi-Bin Ding, Li-Juan Song, Qing Wang, Gajendra Kumar, Yu-Qing Yan, Cun-Gen Ma
Neural Regen Res. 2021 Sep; 16(9): 1702–1710. Published online 2021 Jan 25. doi: 10.4103/1673-5374.306064
PMCID:
PMC8328766
Abstract Article PDF–1.8M