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Cebranopadol Blocks the Escalation of Cocaine Intake and Conditioned Reinstatement of Cocaine Seeking in Rats
Giordano de Guglielmo, Alessandra Matzeu, Jenni Kononoff, Julia Mattioni, Rémi Martin-Fardon, Olivier George
J Pharmacol Exp Ther. 2017 Sep; 362(3): 378–384. Published online 2017 Sep. doi: 10.1124/jpet.117.241042
PMCID:
PMC5539589
Abstract Article PDF–309K

Is Cited by the Following 25 Articles in this Archive:

Novel Opioids in the Setting of Acute Postoperative Pain: A Narrative Review
Ashley Wang, Jasper Murphy, Lana Shteynman, Neil Daksla, Abhishek Gupta, Sergio Bergese
Pharmaceuticals (Basel) 2024 Jan; 17(1): 29. Published online 2023 Dec 25. doi: 10.3390/ph17010029
PMCID:
PMC10819619
Abstract Article PDF–2.6M
Strain and Sex-Related Behavioral Variability of Oxycodone Dependence in Rats
Michelle R. Doyle, Angelica R. Martinez, Ran Qiao, Selen Dirik, Francesca Di Ottavio, Glenn Pascasio, Rémi Martin-Fardon, Christopher Benner, Olivier George, Francesca Telese, Giordano de Guglielmo
Neuropharmacology. Author manuscript; available in PMC 2023 Oct 1.
Published in final edited form as: Neuropharmacology. 2023 Oct 1; 237: 109635. Published online 2023 Jun 15. doi: 10.1016/j.neuropharm.2023.109635
PMCID:
PMC10353778
Abstract Article PDF–983K
Nociceptin Receptor-Related Agonists as Safe and Non-addictive Analgesics
Huiping Ding, Norikazu Kiguchi, MaryBeth Dobbins, E. Alfonso Romero-Sandoval, Shiroh Kishioka, Mei-Chuan Ko
Drugs. Author manuscript; available in PMC 2024 Jun 1.
Published in final edited form as: Drugs. 2023 Jun; 83(9): 771–793. Published online 2023 May 20. doi: 10.1007/s40265-023-01878-5
PMCID:
PMC10948013
Abstract Article PDF–584K
The Downregulation of Opioid Receptors and Neuropathic Pain
Lin Li, Jing Chen, Yun-Qing Li
Int J Mol Sci. 2023 Mar; 24(6): 5981. Published online 2023 Mar 22. doi: 10.3390/ijms24065981
PMCID:
PMC10053236
Abstract Article PDF–981K
Cebranopadol as a Novel Promising Agent for the Treatment of Pain
Wojciech Ziemichod, Jolanta Kotlinska, Ewa Gibula-Tarlowska, Natalia Karkoszka, Ewa Kedzierska
Molecules. 2022 Jul; 27(13): 3987. Published online 2022 Jun 21. doi: 10.3390/molecules27133987
PMCID:
PMC9268744
Abstract Article PDF–1.3M
Attenuated G protein signaling and minimal receptor phosphorylation as a biochemical signature of low side-effect opioid analgesics
Pooja Dasgupta, Anika Mann, Willma E. Polgar, Rainer K. Reinscheid, Nurulain T. Zaveri, Stefan Schulz
Sci Rep. 2022; 12: 7154. Published online 2022 May 3. doi: 10.1038/s41598-022-11189-6
PMCID:
PMC9065038
Abstract Article PDF–2.2M
PPL-138 (BU10038): A bifunctional NOP/mu partial agonist that reduces cocaine self-administration in rats
Andrea Cippitelli, Madeline Martinez, Gilles Zribi, Gerta Cami-Kobeci, Stephen M. Husbands, Lawrence Toll
Neuropharmacology. Author manuscript; available in PMC 2023 Jun 15.
Published in final edited form as: Neuropharmacology. 2022 Jun 15; 211: 109045. Published online 2022 Apr 1. doi: 10.1016/j.neuropharm.2022.109045
PMCID:
PMC9074796
Abstract Article PDF–1.5M
Strategies towards safer opioid analgesics - a review of old and upcoming targets
Balazs Varga, John M. Streicher, Susruta Majumdar
Br J Pharmacol. Author manuscript; available in PMC 2024 Apr 1.
Published in final edited form as: Br J Pharmacol. 2023 Apr; 180(7): 975–993. Published online 2022 Jan 21. doi: 10.1111/bph.15760
PMCID:
PMC9133275
Abstract Article PDF–2.0M
Deep brain stimulation of the nucleus accumbens shell attenuates cocaine withdrawal but increases cocaine self-administration, cocaine-induced locomotor activity, and GluR1/GluA1 in the central nucleus of the amygdala in male cocaine-dependent rats
Marsida Kallupi, Jenni Kononoff, Philippe A. Melas, Johanna S. Qvist, Giordano de Guglielmo, Eric R. Kandel, Olivier George
Brain Stimul. Author manuscript; available in PMC 2023 Jan 1.
Published in final edited form as: Brain Stimul. 2022 Jan-Feb; 15(1): 13–22. Published online 2021 Nov 3. doi: 10.1016/j.brs.2021.11.003
PMCID:
PMC8816878
Abstract Article PDF–642K
Functional Profile of Systemic and Intrathecal Cebranopadol in Non-human Primates
Huiping Ding, Claudio Trapella, Norikazu Kiguchi, Fang-Chi Hsu, Girolamo Caló, Mei-Chuan Ko
Anesthesiology. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Anesthesiology. 2021 Sep 1; 135(3): 482–493. doi: 10.1097/ALN.0000000000003848
PMCID:
PMC8446297
Abstract Article PDF–1.2M
Oxycodone in the Opioid Epidemic: High ‘Liking’, ‘Wanting’, and Abuse Liability
Cherkaouia Kibaly, Jacob A. Alderete, Steven H. Liu, Hazem S. Nasef, Ping-Yee Law, Christopher J. Evans, Catherine M. Cahill
Cell Mol Neurobiol. Author manuscript; available in PMC 2022 Jul 1.
Published in final edited form as: Cell Mol Neurobiol. 2021 Jul; 41(5): 899–926. Published online 2020 Nov 27. doi: 10.1007/s10571-020-01013-y
PMCID:
PMC8155122
Abstract Article PDF–1.0M
Crosstalk between Opioid and Anti-Opioid Systems: An Overview and Its Possible Therapeutic Significance
Ewa Gibula-Tarlowska, Jolanta H. Kotlinska
Biomolecules. 2020 Oct; 10(10): 1376. Published online 2020 Sep 28. doi: 10.3390/biom10101376
PMCID:
PMC7599993
Abstract Article PDF–1.2M
Effects of Cebranopadol on Cocaine-induced Hyperactivity and Cocaine Pharmacokinetics in Rats
Huimei Wei, Linyue Shang, Chang-Guo Zhan, Fang Zheng
Sci Rep. 2020; 10: 9254. Published online 2020 Jun 9. doi: 10.1038/s41598-020-66250-z
PMCID:
PMC7283222
Abstract Article PDF–4.2M
Cebranopadol reduces cocaine self-administration in male rats: Dose, treatment and safety consideration
Huimei Wei, Ting Zhang, Chang-Guo Zhan, Fang Zheng
Neuropharmacology. Author manuscript; available in PMC 2022 Jul 29.
Published in final edited form as: Neuropharmacology. 2020 Aug 1; 172: 108128. Published online 2020 May 8. doi: 10.1016/j.neuropharm.2020.108128
PMCID:
PMC9334146
Abstract Article PDF–1.7M
Oxycodone self-administration and withdrawal behaviors in male and female Wistar rats
Adam Kimbrough, Jenni Kononoff, Sierra Simpson, Marsida Kallupi, Sharona Sedighim, Kenia Palomino, Dana Conlisk, Jeremiah D. Momper, Giordano de Guglielmo, Olivier George
Psychopharmacology (Berl) Author manuscript; available in PMC 2021 May 1.
Published in final edited form as: Psychopharmacology (Berl). 2020 May; 237(5): 1545–1555. Published online 2020 Feb 29. doi: 10.1007/s00213-020-05479-y
PMCID:
PMC7269712
Abstract Article PDF–744K
Dopamine D3 Receptor Antagonism Reverses the Escalation of Oxycodone Self-administration and Decreases Withdrawal-Induced Hyperalgesia and Irritability-Like Behavior in Oxycodone-Dependent Heterogeneous Stock Rats
Giordano de Guglielmo, Marsida Kallupi, Sharona Sedighim, Amy H. Newman, Olivier George
Front Behav Neurosci. 2019; 13: 292. Published online 2020 Jan 14. doi: 10.3389/fnbeh.2019.00292
PMCID:
PMC6971096
Abstract Article PDF–1.5M
NOP Receptor Agonist Ro 64-6198 Decreases Escalation of Cocaine Self-Administration in Rats Genetically Selected for Alcohol Preference
Hongwu Li, Giulia Scuppa, Qianwei Shen, Alessio Masi, Cinzia Nasuti, Nazzareno Cannella, Roberto Ciccocioppo
Front Psychiatry. 2019; 10: 176. Published online 2019 Mar 29. doi: 10.3389/fpsyt.2019.00176
PMCID:
PMC6450143
Abstract Article PDF–1.0M
NOP-related mechanisms in substance use disorders
Roberto Ciccocioppo, Anna Maria Borruto, Ana Domi, Koji Teshima, Nazzareno Cannella, Friedbert Weiss
Handb Exp Pharmacol. Author manuscript; available in PMC 2019 Jul 19.
Published in final edited form as: Handb Exp Pharmacol. 2019; 254: 187–212. doi: 10.1007/164_2019_209
PMCID:
PMC6641545
Abstract Article PDF–380K
Assessment of the Abuse Potential of Cebranopadol in Nondependent Recreational Opioid Users: A Phase 1 Randomized Controlled Study
Karin Göhler, Marta Sokolowska, Kerri A. Schoedel, Robert Nemeth, Elke Kleideiter, Isabella Szeto, Marie-Henriette Eerdekens
J Clin Psychopharmacol. 2019 Jan-Feb; 39(1): 46–56. Published online 2018 Dec 6. doi: 10.1097/JCP.0000000000000995
PMCID:
PMC6319565
Abstract Article PDF–410K
Pain And Opioid Systems, Implications In The Opioid Epidemic.
Nicolas Massaly, Jose A. Morón
Curr Opin Behav Sci. Author manuscript; available in PMC 2020 Apr 1.
Published in final edited form as: Curr Opin Behav Sci. 2019 Apr; 26: 69–74. Published online 2018 Oct 30. doi: 10.1016/j.cobeha.2018.10.002
PMCID:
PMC6457459
Abstract Article PDF–464K
Adolescent cannabinoid exposure induces irritability-like behavior and cocaine cross-sensitization without affecting the escalation of cocaine self-administration in adulthood
Jenni Kononoff, Philippe A. Melas, Marsida Kallupi, Giordano de Guglielmo, Adam Kimbrough, Maria Scherma, Paola Fadda, Denise B. Kandel, Eric R. Kandel, Olivier George
Sci Rep. 2018; 8: 13893. Published online 2018 Sep 17. doi: 10.1038/s41598-018-31921-5
PMCID:
PMC6141462
Abstract Article PDF–2.3M
A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates
Huiping Ding, Norikazu Kiguchi, Dennis Yasuda, Pankaj R. Daga, Willma E. Polgar, James J. Lu, Paul W. Czoty, Shiroh Kishioka, Nurulain T. Zaveri, Mei-Chuan Ko
Sci Transl Med. Author manuscript; available in PMC 2019 Aug 29.
Published in final edited form as: Sci Transl Med. 2018 Aug 29; 10(456): eaar3483. doi: 10.1126/scitranslmed.aar3483
PMCID:
PMC6295194
Abstract Article PDF–1.8M
Nociceptin/orphanin FQ receptor ligands and translational challenges: focus on cebranopadol as an innovative analgesic
G. Calo, D.G. Lambert
Br J Anaesth. 2018 Nov; 121(5): 1105–1114. Published online 2018 Aug 22. doi: 10.1016/j.bja.2018.06.024
PMCID:
PMC6208290
Abstract Article PDF–455K
A systematic review of the role of the nociceptin receptor system in stress, cognition, and reward: relevance to schizophrenia
Muhammad Saad Khan, Isabelle Boileau, Nathan Kolla, Romina Mizrahi
Transl Psychiatry. 2018; 8: 38. Published online 2018 Feb 2. doi: 10.1038/s41398-017-0080-8
PMCID:
PMC5804030
Abstract Article PDF–514K
Cebranopadol, a Mixed Opioid Agonist, Reduces Cocaine Self-administration through Nociceptin Opioid and Mu Opioid Receptors
Qianwei Shen, Yulin Deng, Roberto Ciccocioppo, Nazzareno Cannella
Front Psychiatry. 2017; 8: 234. Published online 2017 Nov 13. doi: 10.3389/fpsyt.2017.00234
PMCID:
PMC5693905
Abstract Article PDF–650K