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Dopamine D3 Receptor Antagonism Reverses the Escalation of Oxycodone Self-administration and Decreases Withdrawal-Induced Hyperalgesia and Irritability-Like Behavior in Oxycodone-Dependent Heterogeneous Stock Rats
Giordano de Guglielmo, Marsida Kallupi, Sharona Sedighim, Amy H. Newman, Olivier George
Front Behav Neurosci. 2019; 13: 292. Published online 2020 Jan 14. doi: 10.3389/fnbeh.2019.00292
PMCID:
PMC6971096
Abstract Article PDF–1.5M

Is Cited by the Following 21 Articles in this Archive:

Oxycodone: A Current Perspective on Its Pharmacology, Abuse, and Pharmacotherapeutic Developments
James E. Barrett, Aryan Shekarabi, Saadet Inan
Pharmacol Rev. 2023 Nov; 75(6): 1062–1118. Published online 2023 Nov. doi: 10.1124/pharmrev.121.000506
Correction in:
Pharmacol Rev. 2023 Dec 15; 76(1): 195.
PMCID:
PMC10595024
Currently embargoed: Free in PMC on Nov 1, 2024; PubMed
Chronic Administration of a Norepinephrine Antagonist Prevents and Partially Reverses Escalation of Cocaine Self-Administration
H. Beldjoud, A. Avelar, G. de Guglielmo, M. Kallupi, S. Sedighim, Nathan Velarde, Brent Boomhower, Nathan Rizo, Lieselot L. G. Carrette, O. George
Addict Biol. Author manuscript; available in PMC 2024 Sep 1.
Published in final edited form as: Addict Biol. 2023 Sep; 28(9): e13316. doi: 10.1111/adb.13316
PMCID:
PMC10614571
Abstract Article PDF–965K
Pharmacological and Physicochemical Properties Optimization for Dual-Target Dopamine D3 (D3R) and μ-Opioid (MOR) Receptors Ligands as Potentially Safer Analgesics
Alessandro Bonifazi, Elizabeth Saab, Julie Sanchez, Antonina L. Nazarova, Saheem A. Zaidi, Khorshada Jahan, Vsevolod Katritch, Meritxell Canals, J. Robert Lane, Amy Hauck Newman
J Med Chem. Author manuscript; available in PMC 2024 May 14.
Published in final edited form as: J Med Chem. 2023 Aug 10; 66(15): 10304–10341. Published online 2023 Jul 19. doi: 10.1021/acs.jmedchem.3c00417
PMCID:
PMC11091828
Abstract Article PDF–4.5M
Strain and Sex-Related Behavioral Variability of Oxycodone Dependence in Rats
Michelle R. Doyle, Angelica R. Martinez, Ran Qiao, Selen Dirik, Francesca Di Ottavio, Glenn Pascasio, Rémi Martin-Fardon, Christopher Benner, Olivier George, Francesca Telese, Giordano de Guglielmo
Neuropharmacology. Author manuscript; available in PMC 2023 Oct 1.
Published in final edited form as: Neuropharmacology. 2023 Oct 1; 237: 109635. Published online 2023 Jun 15. doi: 10.1016/j.neuropharm.2023.109635
PMCID:
PMC10353778
Abstract Article PDF–983K
Opioid withdrawal: role in addiction and neural mechanisms
Sean C. Monroe, Anna K. Radke
Psychopharmacology (Berl) Author manuscript; available in PMC 2024 Jul 1.
Published in final edited form as: Psychopharmacology (Berl). 2023 Jul; 240(7): 1417–1433. Published online 2023 May 10. doi: 10.1007/s00213-023-06370-2
PMCID:
PMC11166123
Abstract Article PDF–408K
Effects of selective dopamine D3 receptor partial agonist/antagonists on oxycodone self-administration and antinociception in monkeys
Kendall Woodlief, Mia I. Allen, Jeremy C. Cornelissen, Matthew L. Banks, Amy Hauck Newman, Michael A. Nader
Neuropsychopharmacology. 2023 Nov; 48(12): 1716–1723. Published online 2023 Apr 28. doi: 10.1038/s41386-023-01590-8
PMCID:
PMC10579365
Currently embargoed: Free in PMC on Nov 1, 2024; PubMed
3,4-Methylenedioxypyrovalerone High-Responder Phenotype as a Tool to Evaluate Candidate Medications for Stimulant Use Disorder
Michelle R. Doyle, Lindsey N. Peng, Jianjing Cao, Kenner C. Rice, Amy Hauck Newman, Gregory T. Collins
J Pharmacol Exp Ther. 2023 Mar; 384(3): 353–362. Published online 2023 Mar. doi: 10.1124/jpet.122.001419
PMCID:
PMC9976791
Abstract Article PDF–1.0M
Dopamine D3/D2 Receptor Ligands Based on Cariprazine for the Treatment of Psychostimulant Use Disorders that May be Dual Diagnosed with Affective Disorders
Emma S. Gogarnoiu, Caleb D. Vogt, Julie Sanchez, Alessandro Bonifazi, Elizabeth Saab, Anver Basha Shaik, Omar Soler-Cedeño, Guo-Hua Bi, Benjamin Klein, Zheng-Xiong Xi, J. Robert Lane, Amy Hauck Newman
J Med Chem. Author manuscript; available in PMC 2024 May 17.
Published in final edited form as: J Med Chem. 2023 Feb 9; 66(3): 1809–1834. Published online 2023 Jan 20. doi: 10.1021/acs.jmedchem.2c01624
PMCID:
PMC11100975
Abstract Article PDF–3.1M
Effects of buprenorphine, methadone, and cariprazine on economic choice between remifentanil and food in squirrel monkeys
Alishan S. Amirali, Jacquelin C. Hecker, Hector M. Figueroa, Devin P. Effinger, Rodrigo A. Montoro, Hank P. Jedema, Caleb D. Vogt, Amy Hauck Newman, Charles W. Schindler, Charles W. Bradberry
Addict Neurosci. Author manuscript; available in PMC 2024 Mar 1.
Published in final edited form as: Addict Neurosci. 2023 Mar; 5: 100065. Published online 2023 Jan 18. doi: 10.1016/j.addicn.2023.100065
PMCID:
PMC9979865
Abstract Article PDF–193K
Current Perspectives on Selective Dopamine D3 Receptor Antagonists/Partial Agonists as Pharmacotherapeutics for Opioid and Psychostimulant Use Disorders
Amy Hauck Newman, Zheng-Xiong Xi, Christian Heidbreder
Curr Top Behav Neurosci. Author manuscript; available in PMC 2024 Jan 1.
Published in final edited form as: Curr Top Behav Neurosci. 2023; 60: 157–201. doi: 10.1007/7854_2022_347
PMCID:
PMC9652482
Abstract Article PDF–1.2M
2‐Arachidonoylglycerol‐mediated endocannabinoid signaling modulates mechanical hypersensitivity associated with alcohol withdrawal in mice
Amanda Morgan, Danielle Adank, Keenan Johnson, Emily Butler, Sachin Patel
Alcohol Clin Exp Res. 2022 Nov; 46(11): 2010–2024. Published online 2022 Oct 12. doi: 10.1111/acer.14949
PMCID:
PMC10091740
Abstract Article PDF–4.6M
A highly D3R-selective and efficacious partial agonist (S)-ABS01-113 compared to its D3R-selective antagonist enantiomer (R)-ABS01-113 as potential treatments for opioid use disorder
Ewa Galaj, Guo-Hua Bi, Benjamin Klein, Briana Hempel, Anver Basha Shaik, Emma S. Gogarnoiu, Jacob Friedman, Jenny Lam, Rana Rais, John F. Reed, Shelley H. Bloom, Tracy L. Swanson, Jennifer L. Schmachtenberg, Amy J. Eshleman, Aaron Janowsky, Zheng-Xiong Xi, Amy Hauck Newman
Neuropsychopharmacology. 2022 Dec; 47(13): 2309–2318. Published online 2022 Jul 25. doi: 10.1038/s41386-022-01379-1
PMCID:
PMC9309443
Abstract Article PDF–2.2M
Altered Accumbal Dopamine Terminal Dynamics Following Chronic Heroin Self-Administration
Brianna E. George, Monica H. Dawes, Emily G. Peck, Sara R. Jones
Int J Mol Sci. 2022 Aug; 23(15): 8106. Published online 2022 Jul 23. doi: 10.3390/ijms23158106
PMCID:
PMC9332320
Abstract Article PDF–2.3M
Glucocorticoid Receptor-Regulated Enhancers Play a Central Role in the Gene Regulatory Networks Underlying Drug Addiction
Sascha H. Duttke, Patricia Montilla-Perez, Max W. Chang, Hairi Li, Hao Chen, Lieselot L. G. Carrette, Giordano de Guglielmo, Olivier George, Abraham A. Palmer, Christopher Benner, Francesca Telese
Front Neurosci. 2022; 16: 858427. Published online 2022 May 16. doi: 10.3389/fnins.2022.858427
PMCID:
PMC9149415
Abstract Article PDF–13M
Escalated (Dependent) Oxycodone Self-Administration Is Associated with Cognitive Impairment and Transcriptional Evidence of Neurodegeneration in Human Immunodeficiency Virus (HIV) Transgenic Rats
Yu Fu, Irene Lorrai, Barry Zorman, Daniele Mercatelli, Chase Shankula, Jorge Marquez Gaytan, Celine Lefebvre, Giordano de Guglielmo, Hyunjae Ryan Kim, Pavel Sumazin, Federico M. Giorgi, Vez Repunte-Canonigo, Pietro Paolo Sanna
Viruses. 2022 Apr; 14(4): 669. Published online 2022 Mar 24. doi: 10.3390/v14040669
PMCID:
PMC9030762
Abstract Article PDF–3.8M
Deep brain stimulation of the nucleus accumbens shell attenuates cocaine withdrawal but increases cocaine self-administration, cocaine-induced locomotor activity, and GluR1/GluA1 in the central nucleus of the amygdala in male cocaine-dependent rats
Marsida Kallupi, Jenni Kononoff, Philippe A. Melas, Johanna S. Qvist, Giordano de Guglielmo, Eric R. Kandel, Olivier George
Brain Stimul. Author manuscript; available in PMC 2023 Jan 1.
Published in final edited form as: Brain Stimul. 2022 Jan-Feb; 15(1): 13–22. Published online 2021 Nov 3. doi: 10.1016/j.brs.2021.11.003
PMCID:
PMC8816878
Abstract Article PDF–642K
Structure Activity Relationships for a Series of Eticlopride-based Dopamine D2/D3 Receptor Bitopic ligands
Anver Basha Shaik, Comfort A. Boateng, Francisco O. Battiti, Alessandro Bonifazi, Jianjing Cao, Li Chen, Rezvan Chitsazi, Saiprasad Ravi, Kuo Hao Lee, Lei Shi, Amy Hauck Newman
J Med Chem. Author manuscript; available in PMC 2022 Oct 29.
Published in final edited form as: J Med Chem. 2021 Oct 28; 64(20): 15313–15333. Published online 2021 Oct 12. doi: 10.1021/acs.jmedchem.1c01353
PMCID:
PMC9617622
Abstract Article PDF–2.1M
Effects of the selective dopamine D3 receptor antagonist PG01037 on morphine-induced hyperactivity and antinociception in mice
Christian A. Botz-Zapp, Stephanie L. Foster, Desta M. Pulley, Briana Hempel, Guo-Hua Bi, Zheng-Xiong Xi, Amy Hauck Newman, David Weinshenker, Daniel F. Manvich
Behav Brain Res. Author manuscript; available in PMC 2022 Oct 11.
Published in final edited form as: Behav Brain Res. 2021 Oct 11; 415: 113506. Published online 2021 Aug 2. doi: 10.1016/j.bbr.2021.113506
PMCID:
PMC8403645
Abstract Article PDF–1.2M
Paradoxical changes in brain reward status during oxycodone self-administration in a novel test of the negative reinforcement hypothesis
Jacques D. Nguyen, Yanabel Grant, Michael A. Taffe
Br J Pharmacol. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Br J Pharmacol. 2021 Sep; 178(18): 3797–3812. Published online 2021 Jun 8. doi: 10.1111/bph.15520
PMCID:
PMC8387405
Abstract Article PDF–1.3M
Dopamine D3 receptor-based medication development for the treatment of opioid use disorder: Rationale, progress, and challenges
Ewa Galaj, Amy Hauck Newman, Zheng-Xiong Xi
Neurosci Biobehav Rev. 2020 Jul; 114: 38–52. Published online 2020 May 3. doi: 10.1016/j.neubiorev.2020.04.024
PMCID:
PMC7252042
Abstract Article PDF–987K
Oxycodone self-administration and withdrawal behaviors in male and female Wistar rats
Adam Kimbrough, Jenni Kononoff, Sierra Simpson, Marsida Kallupi, Sharona Sedighim, Kenia Palomino, Dana Conlisk, Jeremiah D. Momper, Giordano de Guglielmo, Olivier George
Psychopharmacology (Berl) Author manuscript; available in PMC 2021 May 1.
Published in final edited form as: Psychopharmacology (Berl). 2020 May; 237(5): 1545–1555. Published online 2020 Feb 29. doi: 10.1007/s00213-020-05479-y
PMCID:
PMC7269712
Abstract Article PDF–744K