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Depletion of the Microbiome Alters the Recruitment of Neuronal Ensembles of Oxycodone Intoxication and Withdrawal
Sierra Simpson, Adam Kimbrough, Brent Boomhower, Rio McLellan, Marcella Hughes, Kokila Shankar, Giordano de Guglielmo, Olivier George
eNeuro. 2020 May-Jun; 7(3): ENEURO.0312-19.2020. Prepublished online 2020 Apr 27. Published online 2020 May 21. doi: 10.1523/ENEURO.0312-19.2020
PMCID:
PMC7242819
Abstract Article PDF–3.8M

Is Cited by the Following 29 Articles in this Archive:

Sex differences in opioid response: a role for the gut microbiome?
Caitlin Han, Melissa T. Manners, Shivon A. Robinson
Front Pharmacol. 2024; 15: 1455416. Published online 2024 Aug 29. doi: 10.3389/fphar.2024.1455416
PMCID:
PMC11390522
Abstract Article PDF–706K
The interplay between the microbiota and opioid in the treatment of neuropathic pain
Zexiong Gong, Qingsheng Xue, Yan Luo, Buwei Yu, Bo Hua, Zhiheng Liu
Front Microbiol. 2024; 15: 1390046. Published online 2024 Jun 10. doi: 10.3389/fmicb.2024.1390046
PMCID:
PMC11197152
Abstract Article PDF–1.0M
Gut dysbiosis was inevitable, but tolerance was not: temporal responses of the murine microbiota that maintain its capacity for butyrate production correlate with sustained antinociception to chronic voluntary morphine
Izabella Sall, Randi Foxall, Lindsey Felth, Soren Maret, Zachary Rosa, Anirudh Gaur, Jennifer Calawa, Nadia Pavlik, Jennifer L. Whistler, Cheryl A. Whistler
Version 1. bioRxiv. Preprint. 2024 Apr 17. doi: 10.1101/2024.04.15.589671
PMCID:
PMC11042308
Abstract Article PDF–2.0M
Long access heroin self-administration significantly alters gut microbiome composition and structure
Jonathan M. Greenberg, Andrew D. Winters, Branislava Zagorac, David J. Kracht, Dina M. Francescutti, Nazzareno Cannella, Roberto Ciccocioppo, Leah C. Solberg Woods, James Mackle, Gary T. Hardiman, Brittany N. Kuhn, Peter W. Kalivas, Donald M. Kuhn, Mariana Angoa-Perez
Front Psychiatry. 2024; 15: 1369783. Published online 2024 Feb 27. doi: 10.3389/fpsyt.2024.1369783
PMCID:
PMC10927763
Abstract Article PDF–6.1M
Microbiome Depletion Increases Fentanyl Self-Administration and Alters the Striatal Proteome Through Short-Chain Fatty Acids
Rebecca S. Hofford, Katherine R. Meckel, Elizabeth J. Wiser, Weiwei Wang, Jonathon P. Sens, Michelle Kim, Arthur Godino, TuKiet T. Lam, Drew D. Kiraly
eNeuro. 2024 Feb; 11(2): ENEURO.0388-23.2023. Prepublished online 2023 Dec 21. Published online 2024 Feb 9. doi: 10.1523/ENEURO.0388-23.2023
PMCID:
PMC10875718
Abstract Article PDF–2.0M
Blocking IL-17A prevents oxycodone-induced depression-like effects and elevation of IL-6 levels in the ventral tegmental area and reduces oxycodone-derived physical dependence in rats
Saadet Inan, Joseph J Meissler, Shingo Bessho, Sonita Wiah, Cagla Tukel, Toby K Eisenstein, Scott M Rawls
Brain Behav Immun. Author manuscript; available in PMC 2025 Mar 1.
Published in final edited form as: Brain Behav Immun. 2024 Mar; 117: 100–111. Published online 2024 Jan 8. doi: 10.1016/j.bbi.2024.01.001
PMCID:
PMC10932873
Currently embargoed: Free in PMC on Mar 1, 2025; PubMed
Opioid Trail: Tracking Contributions to Opioid Use Disorder from Host Genetics to the Gut Microbiome
Eamonn P. Duffy, Ryan K. Bachtell, Marissa A. Ehringer
Neurosci Biobehav Rev. Author manuscript; available in PMC 2025 Jan 1.
Published in final edited form as: Neurosci Biobehav Rev. 2024 Jan; 156: 105487. Published online 2023 Nov 30. doi: 10.1016/j.neubiorev.2023.105487
PMCID:
PMC10836641
Currently embargoed: Free in PMC on Jan 1, 2025; PubMed
Insights into the Current and Possible Future Use of Opioid Antagonists in Relation to Opioid-Induced Constipation and Dysbiosis
Nariman Essmat, Dávid Árpád Karádi, Ferenc Zádor, Kornél Király, Susanna Fürst, Mahmoud Al-Khrasani
Molecules. 2023 Dec; 28(23): 7766. Published online 2023 Nov 24. doi: 10.3390/molecules28237766
PMCID:
PMC10708112
Abstract Article PDF–1.6M
Multi-omics analysis revealing the interplay between gut microbiome and the host following opioid use
Udhghatri Kolli, Richa Jalodia, Shamsudheen Moidunny, Praveen Kumar Singh, Yuguang Ban, Junyi Tao, Gonzalo Nathaniel Cantu, Eridania Valdes, Sundaram Ramakrishnan, Sabita Roy
Gut Microbes. 2023; 15(2): 2246184. Published online 2023 Aug 23. doi: 10.1080/19490976.2023.2246184
PMCID:
PMC10448978
Abstract Article PDF–5.5M
Clinical and preclinical evidence for gut microbiome mechanisms in substance use disorder
Rebecca S. Hofford, Drew D. Kiraly
Biol Psychiatry. Author manuscript; available in PMC 2025 Feb 15.
Published in final edited form as: Biol Psychiatry. 2024 Feb 15; 95(4): 329–338. Published online 2023 Aug 10. doi: 10.1016/j.biopsych.2023.08.004
PMCID:
PMC10884738
Currently embargoed: Free in PMC on Feb 15, 2025; PubMed
Microbial short-chain fatty acids regulate drug seeking and transcriptional control in a model of cocaine seeking
Katherine R. Meckel, Sierra S. Simpson, Arthur Godino, Emily G. Peck, Jonathon P. Sens, Michael Z. Leonard, Olivier George, Erin S. Calipari, Rebecca S. Hofford, Drew D. Kiraly
Neuropsychopharmacology. 2024 Jan; 49(2): 386–395. Published online 2023 Aug 2. doi: 10.1038/s41386-023-01661-w
PMCID:
PMC10724273
Currently embargoed: Free in PMC on Jan 1, 2025; PubMed
Effect of germ-free status on transcriptional profiles in the nucleus accumbens and transcriptomic response to chronic morphine
Jonathon P. Sens, Rebecca S. Hofford, Drew D. Kiraly
Mol Cell Neurosci. Author manuscript; available in PMC 2024 Sep 1.
Published in final edited form as: Mol Cell Neurosci. 2023 Sep; 126: 103874. Published online 2023 Jun 12. doi: 10.1016/j.mcn.2023.103874
PMCID:
PMC10921993
Abstract Article PDF–1.6M
Sex-dependent gut microbiota-brain-cognition associations: a multimodal MRI study
Shujun Zhang, Huanhuan Cai, Chunli Wang, Jiajia Zhu, Yongqiang Yu
BMC Neurol. 2023; 23: 169. Published online 2023 Apr 27. doi: 10.1186/s12883-023-03217-3
PMCID:
PMC10134644
Abstract Article PDF–2.2M
Linking the gut microbiome to microglial activation in opioid use disorder
Danielle Antoine, Greeshma Venigalla, Bridget Truitt, Sabita Roy
Front Neurosci. 2022; 16: 1050661. Published online 2022 Dec 16. doi: 10.3389/fnins.2022.1050661
PMCID:
PMC9800800
Abstract Article PDF–2.2M
Seeking the Psilocybiome: Psychedelics meet the microbiota-gut-brain axis
John R. Kelly, Gerard Clarke, Andrew Harkin, Sinead C. Corr, Stephen Galvin, Vishnu Pradeep, John F. Cryan, Veronica O'Keane, Timothy G. Dinan
Int J Clin Health Psychol. 2023 Apr-Jun; 23(2): 100349. Published online 2022 Dec 14. doi: 10.1016/j.ijchp.2022.100349
PMCID:
PMC9791138
Abstract Article PDF–1.2M
Neuronal Correlates of Hyperalgesia and Somatic Signs of Heroin Withdrawal in Male and Female Mice
Yocasta Alvarez-Bagnarol, Renata C. N. Marchette, Chase Francis, Marisela Morales, Leandro F. Vendruscolo
eNeuro. 2022 Jul-Aug; 9(4): ENEURO.0106-22.2022. Prepublished online 2022 Jun 21. Published online 2022 Jul 6. doi: 10.1523/ENEURO.0106-22.2022
PMCID:
PMC9267003
Abstract Article PDF–2.1M
Gut-Microbiome Implications in Opioid Use Disorder and Related Behaviors
Bridget Herlihy, Sabita Roy
Adv Drug Alcohol Res. 2022; 2: 10311. Published online 2022 Mar 15. doi: 10.3389/adar.2022.10311
PMCID:
PMC10880781
Abstract Article PDF–784K
Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice
Andrea Dimet-Wiley, Qinglong Wu, Jerrin T. Wiley, Aditya Eswar, Harshini Neelakantan, Tor Savidge, Stan Watowich
Sci Rep. 2022; 12: 484. Published online 2022 Jan 10. doi: 10.1038/s41598-021-03670-5
PMCID:
PMC8748953
Abstract Article PDF–2.2M
Opioid Use, Gut Dysbiosis, Inflammation, and the Nervous System
Richa Jalodia, Yaa Fosuah Abu, Mark Ryan Oppenheimer, Bridget Herlihy, Jingjing Meng, Irina Chupikova, Junyi Tao, Nillu Ghosh, Rajib Kumar Dutta, Udhghatri Kolli, Yan Yan, Eridania Valdes, Madhulika Sharma, Umakant Sharma, Shamsudheen Moidunny, Sabita Roy
J Neuroimmune Pharmacol. Author manuscript; available in PMC 2023 Jun 17.
Published in final edited form as: J Neuroimmune Pharmacol. 2022 Jun; 17(1-2): 76–93. Published online 2022 Jan 7. doi: 10.1007/s11481-021-10046-z
PMCID:
PMC10276355
Abstract Article PDF–919K
Microbiome First Approaches to Rescue Public Health and Reduce Human Suffering
Rodney R. Dietert
Biomedicines. 2021 Nov; 9(11): 1581. Published online 2021 Oct 30. doi: 10.3390/biomedicines9111581
PMCID:
PMC8615664
Abstract Article PDF–420K
Drugs and Bugs: The Gut-Brain Axis and Substance Use Disorders
Sierra Simpson, Rio Mclellan, Emma Wellmeyer, Frederic Matalon, Olivier George
J Neuroimmune Pharmacol. 2022; 17(1-2): 33–61. Published online 2021 Oct 25. doi: 10.1007/s11481-021-10022-7
PMCID:
PMC9074906
Abstract Article PDF–2.4M
Opioid Modulation of the Gut–Brain Axis in Opioid-Associated Comorbidities
Li Zhang, Sabita Roy
Cold Spring Harb Perspect Med. 2021 Sep; 11(9): a040485. doi: 10.1101/cshperspect.a040485
PMCID:
PMC8415294
Abstract Article PDF–2.5M
Bacteria - derived short chain fatty acids restore sympathoadrenal responsiveness to hypoglycemia after antibiotic-induced gut microbiota depletion
Edmund F. LaGamma, Furong Hu, Fernando Pena Cruz, Philip Bouchev, Bistra B. Nankova
Neurobiol Stress. 2021 Nov; 15: 100376. Published online 2021 Aug 3. doi: 10.1016/j.ynstr.2021.100376
PMCID:
PMC8358200
Abstract Article PDF–3.8M
Prenatal Opioid Administration Induces Shared Alterations to the Maternal and Offspring Gut Microbiome: A Preliminary Analysis
Gregory G. Grecco, Yong Gao, Hongyu Gao, Yunlong Liu, Brady K. Atwood
Drug Alcohol Depend. Author manuscript; available in PMC 2022 Oct 1.
Published in final edited form as: Drug Alcohol Depend. 2021 Oct 1; 227: 108914. Published online 2021 Jul 28. doi: 10.1016/j.drugalcdep.2021.108914
PMCID:
PMC8464518
Abstract Article PDF–674K
Fecal microbiota transplantation and antibiotic treatment attenuate naloxone-precipitated opioid withdrawal in morphine-dependent mice
Ana C. Thomaz, Vishakh Iyer, Taylor J. Woodward, Andrea G. Hohmann
Exp Neurol. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Exp Neurol. 2021 Sep; 343: 113787. Published online 2021 Jun 18. doi: 10.1016/j.expneurol.2021.113787
PMCID:
PMC8477666
Abstract Article PDF–1.5M
Alterations in microbiome composition and metabolic byproducts drive behavioral and transcriptional responses to morphine
Rebecca S. Hofford, Nicholas L. Mervosh, Tanner J. Euston, Katherine R. Meckel, Amon T. Orr, Drew D. Kiraly
Neuropsychopharmacology. 2021 Nov; 46(12): 2062–2072. Published online 2021 Jun 14. doi: 10.1038/s41386-021-01043-0
PMCID:
PMC8505488
Abstract Article PDF–2.4M
Contributions of Neuroimmune and Gut-Brain Signaling to Vulnerability of Developing Substance Use Disorders
Kelsey E. Lucerne, Aya Osman, Katherine R. Meckel, Drew D. Kiraly
Neuropharmacology. Author manuscript; available in PMC 2022 Jul 1.
Published in final edited form as: Neuropharmacology. 2021 Jul 1; 192: 108598. Published online 2021 May 6. doi: 10.1016/j.neuropharm.2021.108598
PMCID:
PMC8220934
Abstract Article PDF–378K
Cues conditioned to withdrawal and negative reinforcement: Neglected but key motivational elements driving opioid addiction
Caroline B. Pantazis, Luis A. Gonzalez, Brendan J. Tunstall, Stephanie A. Carmack, George F. Koob, Leandro F. Vendruscolo
Sci Adv. 2021 Apr; 7(15): eabf0364. Published online 2021 Apr 7. doi: 10.1126/sciadv.abf0364
PMCID:
PMC8026136
Abstract Article PDF–294K
Within-treatment changes in a novel addiction treatment program using traditional Amazonian medicine
David M. O’Shaughnessy, Ilana Berlowitz, Robin Rodd, Zoltán Sarnyai, Frances Quirk
Ther Adv Psychopharmacol. 2021; 11: 2045125320986634. Published online 2021 Jan 25. doi: 10.1177/2045125320986634
PMCID:
PMC7841703
Abstract Article PDF–846K