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The DNA Glycosylase NEIL2 Suppresses Fusobacterium-Infection-Induced Inflammation and DNA Damage in Colonic Epithelial Cells
Ibrahim M. Sayed, Anirban Chakraborty, Amer Ali Abd El-Hafeez, Aditi Sharma, Ayse Z. Sahan, Wendy Jia Men Huang, Debashis Sahoo, Pradipta Ghosh, Tapas K. Hazra, Soumita Das
Cells. 2020 Sep; 9(9): 1980. Published online 2020 Aug 28. doi: 10.3390/cells9091980
PMCID:
PMC7565382
Abstract Article PDF–3.9M

Is Cited by the Following 21 Articles in this Archive:

E-cigarettes increase the risk of adenoma formation in murine colorectal cancer model
Ibrahim M Sayed, Anirban Chakraborty, Kaili Inouye, Leanne Dugan, Stefania Tocci, Ira Advani, Kenneth Park, Tapas K Hazra, Soumita Das, Laura E. Crotty Alexander
Version 1. bioRxiv. Preprint. 2024 Aug 26. doi: 10.1101/2024.08.23.609469
PMCID:
PMC11383026
Abstract Article PDF–23M
Application of Fusobacterium nucleatum as a biomarker in gastrointestinal malignancies
Long-Chen Yu, Ya-Ping Li, Yue-Ming Xin, Mai Mao, Ya-Xin Pan, Yi-Xuan Qu, Zheng-Dong Luo, Yi Zhang, Xin Zhang
World J Gastrointest Oncol. 2024 Jun 15; 16(6): 2271–2283. Published online 2024 Jun 15. doi: 10.4251/wjgo.v16.i6.2271
PMCID:
PMC11236247
Abstract Article PDF–1.4M
Gut Microbiome–Colorectal Cancer Relationship
Devvrat Yadav, Chiranjeevi Sainatham, Evgenii Filippov, Sai Gautham Kanagala, Syed Murtaza Ishaq, Thejus Jayakrishnan
Microorganisms. 2024 Mar; 12(3): 484. Published online 2024 Feb 27. doi: 10.3390/microorganisms12030484
PMCID:
PMC10974515
Abstract Article PDF–1.9M
Fusobacterium nucleatum in tumors: from tumorigenesis to tumor metastasis and tumor resistance
Chun Ye, Xiao Liu, Zilun Liu, Chuxuan Pan, Xiaowei Zhang, Zhanyi Zhao, Haitao Sun
Cancer Biol Ther. 2024; 25(1): 2306676. Published online 2024 Jan 30. doi: 10.1080/15384047.2024.2306676
PMCID:
PMC10829845
Abstract Article PDF–5.3M
Fusobacterium nucleatum promotes inflammatory and anti-apoptotic responses in colorectal cancer cells via ADP-heptose release and ALPK1/TIFA axis activation
Camille Martin-Gallausiaux, Laurène Salesse, Diego Garcia-Weber, Ludovica Marinelli, Fabienne Beguet-Crespel, Vincent Brochard, Camille Le Gléau, Alexandre Jamet, Joël Doré, Hervé M. Blottière, Cécile Arrieumerlou, Nicolas Lapaque
Gut Microbes. 2024; 16(1): 2295384. Published online 2023 Dec 21. doi: 10.1080/19490976.2023.2295384
PMCID:
PMC10761154
Abstract Article PDF–2.4M
The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infection
Nisha Tapryal, Anirban Chakraborty, Kaushik Saha, Azharul Islam, Lang Pan, Koa Hosoki, Ibrahim M. Sayed, Jason M. Duran, Joshua Alcantara, Vanessa Castillo, Courtney Tindle, Altaf H. Sarker, Maki Wakamiya, Victor J. Cardenas, Gulshan Sharma, Laura E. Crotty Alexander, Sanjiv Sur, Debashis Sahoo, Gourisankar Ghosh, Soumita Das, Pradipta Ghosh, Istvan Boldogh, Tapas K. Hazra
Nat Commun. 2023; 14: 8169. Published online 2023 Dec 9. doi: 10.1038/s41467-023-43938-0
PMCID:
PMC10710473
Abstract Article PDF–2.5M
Base Excision Repair: Mechanisms and Impact in Biology, Disease, and Medicine
Dhara Gohil, Altaf H. Sarker, Rabindra Roy
Int J Mol Sci. 2023 Sep; 24(18): 14186. Published online 2023 Sep 16. doi: 10.3390/ijms241814186
PMCID:
PMC10531636
Abstract Article PDF–2.0M
Phosphorylation of the Human DNA Glycosylase NEIL2 Is Affected by Oxidative Stress and Modulates Its Activity
Camilla Myrup Holst, Nanna Brøndum Andersen, Vibeke Thinggaard, Mine Tilken, Sofie Lautrup, Cinzia Tesauro, Tinna Stevnsner
Antioxidants (Basel) 2023 Feb; 12(2): 355. Published online 2023 Feb 2. doi: 10.3390/antiox12020355
PMCID:
PMC9952225
Abstract Article PDF–4.1M
Diagnosis and functional prediction of microbial markers in tumor tissues of sporadic colorectal cancer patients associated with the MLH1 protein phenotype
Anchao Zhu, Yingying Liu, Zongmin Li, Ying He, Lijing Bai, Youtian Wu, Yuying Zhang, Ying Huang, Ping Jiang
Front Oncol. 2022; 12: 1116780. Published online 2023 Jan 23. doi: 10.3389/fonc.2022.1116780
PMCID:
PMC9899897
Abstract Article PDF–4.5M
Association of Early Childhood Caries with Bitter Taste Receptors: A Meta-Analysis of Genome-Wide Association Studies and Transcriptome-Wide Association Study
Ekaterina Orlova, Tom Dudding, Jonathan M. Chernus, Rasha N. Alotaibi, Simon Haworth, Richard J. Crout, Myoung Keun Lee, Nandita Mukhopadhyay, Eleanor Feingold, Steven M. Levy, Daniel W. McNeil, Betsy Foxman, Robert J. Weyant, Nicholas J. Timpson, Mary L. Marazita, John R. Shaffer
Genes (Basel) 2023 Jan; 14(1): 59. Published online 2022 Dec 24. doi: 10.3390/genes14010059
PMCID:
PMC9858612
Abstract Article PDF–1.0M
The Role of Fusobacterium nucleatum in Colorectal Cancer Cell Proliferation and Migration
Zihong Wu, Qiong Ma, Ying Guo, Fengming You
Cancers (Basel) 2022 Nov; 14(21): 5350. Published online 2022 Oct 30. doi: 10.3390/cancers14215350
PMCID:
PMC9656216
Abstract Article PDF–2.1M
The DNA glycosylase NEIL2 plays a vital role in combating SARS-CoV-2 infection
Tapas Hazra, Nisha Tapryal, Anirban Chakraborty, Kempaiah Rayavara, Maki Wakamiya, Azharul Islam, Lang Pan, Jason Hsu, Vivian Tat, Junki Maruyama, Koa Hosoki, Ibrahim Sayed, Joshua Alcantara, Vanessa Castillo, Courtney Tindle, Altaf Sarker, Victor Cardenas, Gulshan Sharma, Laura Crotty Alexander, Sanjiv Sur, Gourisankar Ghosh, Slobodan Paessler, Debashis Sahoo, Pradipta Ghosh, Soumita Das, Istvan Boldogh, Chien-Te Tseng
Version 1. Res Sq. Preprint. 2022 May 27. doi: 10.21203/rs.3.rs-1690354/v1
Published in:
Nat Commun. 2023; 14: 8169.
PMCID:
PMC9164514
Abstract Article PDF–1.3M
Fusobacterium nucleatum: a new player in regulation of cancer development and therapeutic response
Tengda Zhao, Xueping Wang, Liwu Fu, Ke Yang
Cancer Drug Resist. 2022; 5(2): 436–450. Published online 2022 May 12. doi: 10.20517/cdr.2021.144
PMCID:
PMC9255244
Abstract Article PDF–2.2M
Targeting the DNA Damage Response Pathway as a Novel Therapeutic Strategy in Colorectal Cancer
Fabio Catalano, Roberto Borea, Silvia Puglisi, Andrea Boutros, Annalice Gandini, Malvina Cremante, Valentino Martelli, Stefania Sciallero, Alberto Puccini
Cancers (Basel) 2022 Mar; 14(6): 1388. Published online 2022 Mar 9. doi: 10.3390/cancers14061388
PMCID:
PMC8946235
Abstract Article PDF–749K
A Low-Activity Polymorphic Variant of Human NEIL2 DNA Glycosylase
Zarina I. Kakhkharova, Dmitry O. Zharkov, Inga R. Grin
Int J Mol Sci. 2022 Feb; 23(4): 2212. Published online 2022 Feb 17. doi: 10.3390/ijms23042212
PMCID:
PMC8879280
Abstract Article PDF–2.4M
Low Abundance Fusobacterium Nucleatum Supports Early Pregnancy Development – An In Vitro Study
Martha Heusler, Rebekka Einenkel, Jens Ehrhardt, Damián Oscar Muzzio, Marek Zygmunt
Front Immunol. 2021; 12: 698045. Published online 2021 Aug 31. doi: 10.3389/fimmu.2021.698045
PMCID:
PMC8438310
Abstract Article PDF–4.3M
Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19
Courtney Tindle, MacKenzie Fuller, Ayden Fonseca, Sahar Taheri, Stella-Rita Ibeawuchi, Nathan Beutler, Gajanan Dattatray Katkar, Amanraj Claire, Vanessa Castillo, Moises Hernandez, Hana Russo, Jason Duran, Laura E Crotty Alexander, Ann Tipps, Grace Lin, Patricia A Thistlethwaite, Ranajoy Chattopadhyay, Thomas F Rogers, Debashis Sahoo, Pradipta Ghosh, Soumita Das
eLife. 2021; 10: e66417. Published online 2021 Aug 13. doi: 10.7554/eLife.66417
PMCID:
PMC8463074
Abstract Article PDF–14M
Functional assays with human patient-derived enteroid monolayers to assess the human gut barrier
Ibrahim M. Sayed, Courtney Tindle, Ayden G. Fonseca, Pradipta Ghosh, Soumita Das
STAR Protoc. 2021 Sep 17; 2(3): 100680. Published online 2021 Jul 17. doi: 10.1016/j.xpro.2021.100680
PMCID:
PMC8313751
Abstract Article PDF–4.3M
Intrapulmonary administration of purified NEIL2 abrogates NF-κB–mediated inflammation
Nisha Tapryal, Shandy Shahabi, Anirban Chakraborty, Koa Hosoki, Maki Wakamiya, Gobinda Sarkar, Gulshan Sharma, Victor J. Cardenas, Istvan Boldogh, Sanjiv Sur, Gourisankar Ghosh, Tapas K. Hazra
J Biol Chem. 2021 Jan-Jun; 296: 100723. Published online 2021 Apr 28. doi: 10.1016/j.jbc.2021.100723
PMCID:
PMC8164026
Abstract Article PDF–3.6M
Role of the β-Catenin/REG Iα Axis in the Proliferation of Sessile Serrated Adenoma/Polyps Associated with Fusobacterium nucleatum
Heihachiro Nishimura, Hirokazu Fukui, Xuan Wang, Nobuhiko Ebisutani, Takashi Nakanishi, Toshihiko Tomita, Tadayuki Oshima, Seiichi Hirota, Hiroto Miwa
Pathogens. 2021 Apr; 10(4): 434. Published online 2021 Apr 6. doi: 10.3390/pathogens10040434
PMCID:
PMC8067346
Abstract Article PDF–4.1M
Modeling colorectal cancers using multidimensional organoids
Ibrahim M. Sayed, Amer Ali Abd El-Hafeez, Priti P. Maity, Soumita Das, Pradipta Ghosh
Adv Cancer Res. Author manuscript; available in PMC 2022 Mar 26.
Published in final edited form as: Adv Cancer Res. 2021; 151: 345–383. Published online 2021 Mar 26. doi: 10.1016/bs.acr.2021.02.005
PMCID:
PMC8221168
Abstract Article PDF–875K