Schizophrenia: Vaisnvi Muthoovaloo 102011430
Schizophrenia: Vaisnvi Muthoovaloo 102011430
Anamnesis
Apperance Demeanor Speech Grooming, hygiene Motor activity, attitude Rate, volume, organization, clarity, latency, candor
Affect
Mood Thought process Thought content Sensorium Insight Judgement
Anamnesis
Pemeriksaan Fisik
Pemeriksaan Penunjang
CBC Liver function test Urine drug abuse Electrolyte abnormalities Neuropsychological testing
Radiology
Working diagnosis
Schizophrenia
Differential diagnosis
Schizoaffective disorder Bipolar affective disorder Cocaine-related psychiatric disorder
Etiology
Uncertain but several risk factors need to be considered.
Genetics Consideration
1st degree & 2nd degree relative
Environmental
Abnormalities of pregnancy and delivery [2%] Maternal Influenza 2nd trimester [2%] Fetal Malnutrition [2%] Winter & Low Social Class birth [1.1%]
Epidemiology
Types of schizophrenia
Catatonic
Negative symptoms
Neurocognitive symptoms
Positive symptoms
Clinical manifestations
Mood symptoms
Anti-psychotic medication
Ist generation 2nd generation Dopamine D2 antagonist Chlorpromazine, haloperidol Clozapine most effective but not first line Loxapine inhaled acute agitation
Other medications
antidepressants, mood stabilizers, anxiolytic agents
Complications
Substance abuse
Depression
Anxiety
Violence
Prognosis
20% 20% 20%
Complete recovery
Recurrent acute illness Chronic disease starting acutely Chronic disease starting insidiously Suicide
20%
10-15%