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VII.

DRUG STUDY
DRUG
Date ordered:
August 04, 2010
Generic name:
Dexamethasone
Brand name:
-Classification:
Anti inflammatory
Glucocorticoid
Dosage:
1.8 mg IV q6

INDICATION

ACTION

Specific
The patient was given
Adjunctive treatment dexamtehasone 1.8 mg
in bacterial meningitis. through IV every 6
hours to decreases
General
inflammation, mainly by
Cerebral edema
stabilizing leukocyte
Allergic and
lysosomal membranes;
inflammatory
suppresses immune
conditions
response; stimulates
Shock
bone marrow; and
Tuberculosis
influences protein, fat
meningitis
and carbohydrate
metabolism.

SIDE/ADVERSE EFFECTS
CNS: euphoria, insomnia,
psychotic behavior,
pseudotumor cerebri,
vertigo, headache,
paresthesia, seizures,
depression.
CV: hypertension, edema,
arrythmias,
thromboembolism.
EENT: cataracts, glaucoma.
GI: peptic ulceration, GI
irritation, increased
appetite, pancreatitis,
nausea, vomiting.
GU: increase urine glucose,
and calcium levels
Metabolic: hypokalemia,
hyperglycemia
Musculoskeletal: muscle
weakness
Skin: Delayed wound
healing
Other: Susceptibility to
infections.

NURSING
CONSIDERATION
1. Determine whether
patient is sensitive to
other corticosteroids
2. Most adverse
reactions to
corticosteroids are
dose-or durationdependent.
3. For better results and
less toxicity, give
once daily dose in
morning.
4. Give oral dose with
food when possible.
Patient may need
drugs to prevent GI
irritation.
5. Give I.M injection
deeply into gluteal
muscle. Rotate
injection sites to
prevent muscle
atrophy. Avoid
subcutaneous
injection because
atrophy and sterile
abscesses may occur.

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