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PULMONARY EDEMA slide #30

BY: Martin Allen Buenaventura Click to edit Master subtitle style 2b - group2

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CASE

A 60 year old female, known hypertensive and diagnosed of CONGESTIVE HEART FAILURE complained of orthopnea, paroxysmal nocturnal dsypnea. Atrial fibrillation occurred and patient succumbed.

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What is Edema?

Is defined as an abnormal increase in interstitial fluid within a tissue

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Etiology

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Etiology

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etiology

Cardiogenic primary cause Increased hydrostatic pressure Decreased oncotic pressure:Nephrotic syndrome, hypoproteinemia Lymphatic obstruction

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pathogenesis

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Left sided heart failure (MI, cardiomyopathy,HPN, valvular dse decrease pumping ability to the systemic circulation congestion and accumulation of blood in the pulmonary area fluid leaks out of the intravascular space to the interstitium

MORPHOLOGICAL CHANGES (GROSS)

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MORPHOLOGICAL CHANGES (GROSS)

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MORPHOLOGICAL CHANGES (GROSS)


2-3 times heavier than the normal weight Lungs appear red due to congestion Sectioning of the lung reveals a frothy blood tinged mixture of air and edema fluid. Brown induration

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MORPHOLOGICAL CHANGES (histologic)


There is thickening of alveolar septal wall Congestion of alveolar capillaries Transudation-Alveolar lumen is filled withtransudate(paleeosinophilic, finely granular), a liquid which replaces the air.

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MORPHOLOGICAL CHANGES (histologic)

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Clinical Manifestations of Pulmonary Edema


Tachypnea (+) crackles Cyanosis Dyspnea Orthopnea Coughing with blood-tinged sputum

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