The document provides information on various anesthetics and anthelmintic drugs including their generic and trade names, manufacturers, prices, dosage forms, indications, and pregnancy categories. It includes a table with details on mepivacaine, isoflurane, benzocaine, prilocaine and lidocaine anesthetics as well as a section on albendazole, mebendazole, ivermectin, pyrantel pamoate, and praziquantel anthelmintics listing their chemical names, brands, manufacturers, and other specifications. The document appears to be research or educational material comparing properties of different anesthetic and anthelmintic medications.
The document provides information on various anesthetics and anthelmintic drugs including their generic and trade names, manufacturers, prices, dosage forms, indications, and pregnancy categories. It includes a table with details on mepivacaine, isoflurane, benzocaine, prilocaine and lidocaine anesthetics as well as a section on albendazole, mebendazole, ivermectin, pyrantel pamoate, and praziquantel anthelmintics listing their chemical names, brands, manufacturers, and other specifications. The document appears to be research or educational material comparing properties of different anesthetic and anthelmintic medications.
The document provides information on various anesthetics and anthelmintic drugs including their generic and trade names, manufacturers, prices, dosage forms, indications, and pregnancy categories. It includes a table with details on mepivacaine, isoflurane, benzocaine, prilocaine and lidocaine anesthetics as well as a section on albendazole, mebendazole, ivermectin, pyrantel pamoate, and praziquantel anthelmintics listing their chemical names, brands, manufacturers, and other specifications. The document appears to be research or educational material comparing properties of different anesthetic and anthelmintic medications.
Polocaine MPF (Mepivacaine hydrochloride) Hospira, US
Dentsply Pharmaceutical , US
APP Pharmaceutical , US $17.75
$12.25
$16.75 Injectable solution (1%, 1.5%, 2%, 3%)
Injectable solution (1%, 1.5%, 2%, 3%)
Injectable solution (1%, 1.5%, 2%, 3%) This medication is a local anesthetic, prescribed for inducing local or regional analgesia and anesthesia during surgical procedures, labor, or delivery. It works by preventing nerves from transmitting painful impulses to the brain. C (Either studies in animals have revealed adverse effects on the fetus and there are no controlled studies in women or studies in women and animals are not available.) Isoflurane
Aerrane
Florane
Baxter Healthcare
Singapore Pharmawealth Lifesciences
P1,500
Inhalation solution 100mL x1s
Inhalation solution 100% x 100mL x 1s
General inhalation anesthetic B (Either animal- reproduction studies have not demonstrated a foetal risk but there are
Forane
Isocane
Phil Pharmawealth/ Minrad Isoflurane Abbott
Lunan
Minrad P 4,327.58
Inhalation solution 100mL x1s
Inhalation solution 100mL x1s
Inhalation solution 100mL x1s
no controlled studies in pregnant women or animal reproduction studies have shown any adverse effects.) Benzocaine
Ethyl 4- aminobenzoate Auralgan
United Home Burn Ointment
Orajel (UK)
Dermoplast (US)
Anbesol (US) Wyeth
United Home
Church & Dwight UK Ltd Pretige Brands, Inc.
Pfizer
Pfizer 559.03 php
70.0php (15g)
92.0php (30g)
5.25 pounds
10.79 dollars
6.27 dollars
Otic Solution (14mg/mL)
Ointment (10mg/g)
Mouth Gel ( 10% w/w)
Spray (20%)
Oral gel (20%)
Benzocaine is used to reduce pain or discomfort caused by minor skin irritations, sore throat, sunburn, teething pain, vaginal or rectal irritation and many other minor pain on a surface of the body C(Either studies in animals have revealed adverse effects on the fetus and there are no controlled studies in women or studies in women and animals are not available.) Prilocaine and Lidocaine
B(Either animal- reproduction studies have not demonstrated a foetal risk but there are no controlled studies in pregnant women or animal reproduction studies have shown any adverse effects.) Bupivacaine
ACI Ltd. 0.25% x 20ml vial: 35.40 IP; 0.5% x 30ml vial: 60.00 IP
0.25% x 20ml vial: 45.00 IP
4ml amp x 10s pack: 280.00 MRP
4ml amp x 0.25% or 0.5% Solution for injection
0.25% Solution for injection
80mg/ml Solution for injection
80mg/ml Bupivacaine is indicated for single dose- infiltration into surgical site to produce postsurgical anesthesia. It is also indicated for Peripheral nerve block, sympathetic nerve block, and caudal blocks. C (it has an action that crosses the placenta it has been approved as an obstetrical anesthesia. However Bupivacaine is excreted into human milk. The risk of continuing
ANTHELMINTICS GENERIC NAME IUPAC NAME STRUCTURE BRAND NAME INDICATION PREGNANCY CATEGORY 1.Albendazole methyl N-[6- (propylsulfanyl)-1H- 1,3-benzodiazol-2- yl]carbamate
1.HYEMEX chewable tab 400 mg (P25/tab) manufactured by: Blue sky Treatment of single & mixed intestinal nematode infections including ascariasis, Category C Either studies in animals have revealed adverse
BUPI Plain
Popular Pharmaceutical s Ltd. 10s pack: 300.00 IP
0.5% x 30ml vial: 60.00 MRP Solution for injection
0.5% Solution for injection
However it is most commonly used as local anesthetic in epidural anesthesia during labor. and discontinuing the drug is being discussed with the patient.) LIDOCAINE HCl 2- (diethylamino)- N-(2,6- dimethylphenyl) acetamide Euro-Med Lidocaine HCl
Elin Lidocaine HCl
Phil Pharmawealth/ Atlantic LidocaINE
Xepacaine
Xylocaine Euro-Med
Elin
Atlantic Lab
Gland Pharma
Astra Zeneca
(2mL) P 8.96/amp (5mL) P 12.32/amp (20mL) P 36.96/vial (50mL) P 66.08/vial P27.50 P65
P 1,757
P2,125 20 mg /mL 2% Solution for injection
2% x 10mL 50mL
20mg/mL
20mg/mL
10mg/dose(10 %) (2%) Local and regional anesth: local infiltration and peripheral and central nerve block.
B ( Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well- controlled studies in pregnant women )
5.AZOLE 400 mg/tab (20s pack/80 MRP) manufactured by: Bio-pharma Laboratories Ltd. enterobiasis & trichuriasis. effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus. 2.Mebendazole methyl (5-benzoyl-1H- benzimidazol-2- yl)carbamate
1.BENDEX 100mg & 500 mg/tab (100mg x 30s pack/22.20 MRP; 500mg x 30s pack/65.99 MRP)
2.ERMOX 100 Broad-spectrum anthelmintic indicated for the treatment of nematode infestations, including roundworm, hookworm, whipworm, threadworm, pinworm, and the intestinal form of trichinosis prior to its spread into the tissues beyond the digestive tract
Mebendazole is Pregnancy Category C, which means that it has been shown to cause ill effects in pregnancy in animal models and there are no adequate studies of its effects in human pregnancy. It is unknown whether it can be passed by breast feeding.
5. EVRINA 3mg tab (1x50tabs= 8.50 US dollars) Manufactured by: Pride Healthcare [USA] Used in humans in the treatment of onchocerciasis and effective against other worm infestations such as strongyloidiasis, ascariasis, trichuriasis, filariasis, and enterobiasis. B3 (Australia), C (US) 4. Pyrantel Pamoate 4-[(3-Carboxy-2- hydroxynaphthalen-1- yl)methyl]-3- hydroxynaphthalene- 2-carboxylic acid; 1- methyl-2-[(E)-2- thiophen-2-ylethenyl]- 5,6-dihydro-4H- pyrimidine
For control of hyperglycemia in gliclazide- responsive diabetes mellitus of stable, mild, non- ketosis prone, type 2 diabetes. It is used when diabetes cannot be controlled by proper dietary management and exercise or when insulin therapy is not appropriate.
Category C
Name Structure IUPAC Name 5 Trade Names (with manufacturer and selling price) Dosage forms and strengths Clinical Indication Pregnancy category
Metformin HCl
1- carbamimidamido- N, N- dimethylmethanimi damide
For people with Type 2 diabetes. Metformin is sometimes used in combination with insulin or other medications, but it is not for treating Type 1 diabetes.
Actos (Takeda Pharmaceutical Company ) 15 mg x 30s (Php2,027.30) 30 mg x 30s (Php 3,254.55) Glucozone (Vitalink) 500 mg x 100s (Php 320/box ; Php 3.20/tab) Piozone (LR Imperial, Inc) 15 mg x 10s, 30s (Php 509.45/box) 30 mg x 10s, 30s (Php 679.25/box) Prialta (OEP Philippines) 15 mg x 50s (Php 794.18) Actos tablet 15 mg, 30 mg Glucozone tablet 500 mg Piozone tablet 15 mg, 30 mg Prialta tablet 15 mg, 30 mg, 45 mg Zolid tablet 15 mg, 30 mg, 45 mg Used to lower high blood sugar associated with type 2 diabetes. It helps insulin to work more effectively. By keeping blood sugar at a desired level, It can help prevent or delay the long-term problems associated with uncontrolled high blood sugar (e.g., kidney disease, eye problems, nerve problems, heart disease). It increases
Category C
30 mg x 50s (Php 1,069.09) 45 mg x 50s (Php 1,069.09) Zolid (Getz Pharma) 15 mg x 14s (Php 249.50) 30 mg x 14s (Php 261.75) 45 mg x 14s (Php 336.50)
insulin sensitivity in muscle and adipose tissue, and inhibits hepatic gluconeogenesis Name Structure IUPAC Name 5 Trade Names (with manufacturer and selling price) Dosage forms and strengths Clinical Indication Pregnancy category
Trade Names: Manufacturer: Price: 1. Vidastat 20mg Unilab Php 43.39 /tab 2. Cholestad 20mg Littman Drug Corp Php 2,1.37/100 tab 3. Zocor 20mg Merck & Co. Php 41.22/tab 4. Alvastin 10mg Allied Chemicals & Pharmaceuticals Pvt.Ltd. Php 5.04/tab 5. Zosta 40 mg US Vitamins Limited Php 15.00/tab Dosage Forms and Strength: Tablet 5 mg, 10 mg, 20 mg, 40 mg, Clinical Indication: For the treatment of hypercholesterolemia and for the reduction in the risk of cardiac heart disease mortality and cardiovascular events. It can also be used in adolescent patients for the treatment of heterozygous familial hypercholesterolemia. Pregnancy Category: X
Trade Names: Manufacturer: Price: 1. Fenoflex LR Imperial, Inc. 30's (P1030.49/box) 2. Fenogal SMB Technology 30's (P885.00/pack) 3. Lofibra OEP Phils. Inc 50's (P1090.00/pack) 4. Lipway SR Cathay Drug Co. Inc. 30's (P1041.60/pack) 5. Trolip Gracio Med Phils., Inc. 30's (P823.73/pack) Dosage Forms and Strength: 160 mg capsule, 200 mg capsule, 250 mg capsule, 300 mg capsule Clinical Indication: It is mainly used to reduce cholesterol levels in patients at risk of cardiovascular disease. It reduces both low-density lipoprotein (LDL) and very low density lipoprotein (VLDL) levels, as well as increasing high- density lipoprotein (HDL) levels and reducing triglycerides level. Pregnancy Category: C
Trade Names: Manufacturer: Price: 1. Bestor Biocon Limited P32.40/10 tabs 2. Fortius Nicholas Piramal India Ltd. P35.28/10 tabs 3. Crestor AstraZeneca P1,730/30 tabs 4. Rosucol Ajanta Pharma Phil P493.69/30 tabs 5. Rustor InnoGen Pharma P1,065/30 tabs Dosage Forms and Strength: 5mg, 10mg, 20mg, and 40mg film-coated tablets Clinical Indication: Rosuvastatin is used for the reduction of blood total cholesterol, HDL cholesterol and triglyceride levels, and to increase HDL cholesterol levels. Rosuvastatin also is used for reducing the risk of heart attacks, stroke, and arterial revascularization procedures in patients without clinically evident coronary heart disease but with multiple risk factors for heart disease. Pregnancy Category: X
Trade Names: Manufacturer: Price: 1. Canef (EU) 20 & 40 mg AstraZeneca 84s (P2,680.70) 84s (P2,777.32) 2. Cranoc (US) 20 & 40 mg Astellas 50s (P2567.29) 50s (P3153.52) 3. Lescol 40 mg Novartis Pharmaceutical 28s (P1,650) 4. Lescol XL 80 mg Novartis Pharmaceutical 28s (P1,912.65) 5. Liposit (US) 20 & 40 mg Ferrer International 28s (P1890.29) 28s (P2541.67) Dosage Forms and Strength: 20 mg Capsule, 40mg Capsule, 40 mg Tablet, 80mg Tablet Clinical Indication: To be used as an adjunct to dietary therapy to prevent cardiovascular events. May be used as secondary prevention in patients with coronary heart disease (CHD) to reduce the risk of requiring coronary revascularization procedures, for reducing progression of coronary atherosclerosis in hypercholesterolemic patients with CHD, and for the treatment of primary hypercholesterolemia and mixed dyslidipidemia To be used as an adjunct to dietary therapy to prevent cardiovascular events. May be used as secondary prevention in patients with coronary heart disease (CHD) to reduce the risk of requiring coronary revascularization procedures, for reducing progression of coronary atherosclerosis in hypercholesterolemic patients with CHD, and for the treatment of primary hypercholesterolemia and mixed dyslidipidemia. To be used as an adjunct to dietary therapy to prevent cardiovascular events. May be used as secondary prevention in patients with coronary heart disease (CHD) to reduce the risk of requiring coronary revascularization procedures, for reducing progression of coronary atherosclerosis in hypercholesterolemic patients with CHD, and for the treatment of primary hypercholesterolemia and mixed dyslidipidemia. Pregnancy Category: X Structure:
Trade Names: Manufacturer: Price: 1.Lipitor 10mg Pfizer 100's (P3272.75/pack) 2. Ator-10 InnoGen Pharma 30's (P676.50/pack) 3. Avamax 20mg Therapharma 100's (P28.57/pack) 4. Atorwin 10mg Sanofi-Aventis 30's (P552.27/pack) 5. Xantor 80mg Sandoz 30's (P34.00/film-coated tab) Dosage Forms and Strength: 10 mg capsule, 20 mg capsule, 40 mg capsule, 80 mg capsule Clinical Indication: Atorvastatin is used for the treatment of elevated total cholesterol, LDL, and triglycerides and to elevate HDL cholesterol. The effectiveness of atorvastatin in lowering cholesterol is dose-related, meaning that higher doses reduce cholesterol more. It prevents angina, stroke, heart attack, hospitalization for congestive heart failure, and revascularization procedures in individuals with coronary artery disease. It also reduces the risk of myocardial infarction (heart attack), stroke, angina and revascularization procedures in adults with multiple risk factors for coronary artery disease. Atorvastatin also prevents heart attacks and strokes in patients with type 2 diabetes with multiple risk factors for coronary artery disease. Pregnancy Category: X
ANALGESIC / ANTI-INFLAMMATORY DRUGS
Generic Name Structure IUPAC name Trade Name Manufacturer Selling Price Dosage Form/s Strengths Clinical Indication Pregnancy Category Celecoxib
4-[5-(4- methylphenyl)-3- (trifluoromethyl)- 1H-pyrazol-1-yl] benzene-1- sulfonamide Aubrex Corbridge P26.00/cap Capsule 200 mg Treatment of rheumatic arthritis, juvenile idiopathic arthritis, osteoarthritis, signs and symptoms of ankylosing spondylitis, and of adenomatous colorectal polyps, and management of acute pain Category C OR Category D (in third trimester or near delivery) Brexen Xeno P19.80/cap Capsule 200 mg Celcoxx Getz Pharma P18.83/cap Capsule 100 mg P27.24/cap 200 mg P42.27/cap 400 mg Celebrex Pfizer P41.66/cap Capsule 100 mg P58.91/cap 200 mg P79.50/cap 400 mg Celeflam Flamingo P17.66/cap Capsule 200 mg Diclofenac
2-[2-(2,6- dichlorophenyl- amino)phenyl]acetic acid Difenax GXI P5.57/tab Tablet 50 mg Treatment of rheumatic arthritis, osteoarthritis, juvenile rheumatic arthritis, ankylosing spondylitis, and painful inflammation and swelling Category C OR Category D (in third trimester or near delivery) Cataflam Novartis Healthcare P13.14/tab Sugar- coated Tablet 25 mg P22.25/tab 50 mg Clofil Filadams P6.00/tab EC Tablet 50 mg Votan Taiwan Biotech P18.00/tab Tablet 100 mg Arthrotec Pfizer (USA) P39.20/tab MR Tablet 75 mg Generic Name Structure IUPAC name Trade Name Manufacturer Selling Price Dosage Form/s Strengths Clinical Indication Pregnancy Category Ibuprofen
(RS)-2-[4-(2-methyl propyl)phenyl]pro- panoic acid Advil Pfizer Consumer P6.83/caplet Caplet 200 mg Management of mild to moderate Category C OR Category D P74.25/bottle (60 mL) Oral Suspension 100 mg/ 5 mL P7.39/cap Softgel Capsule 200 mg paint and inflammation (menstrual pain, dental pain, headaches, migraines, sprains, strains), and treatment of rheumatic arthritis (juvenile arthritis, ankylosing spondylitis, osteoarthritis, and acute gouty arthritis) (in third trimester or near delivery) Brufen Abbott P73.50/bottle (60 mL) Oral Suspension 100 mg/ 5 mL P13.13/tab Tablet 600 mg Dolan FP Pediatrica P70.75/bottle (15 mL) Oral Drops 100 mg/ 2.5 mL P115.51/bottle (60 mL) Oral Suspension 200 mg/ 5 mL P69.31/bottle (60 mL) 100 mg/ 5 mL Faspic Zambon P22.40/tab Tablet 400 mg Midol Invida P6.14/tab Tablet 200 mg Category B OR Category D (in third trimester) P14.55/tab 400 mg Mefenamic Acid
2-[(2,3- dimethylphenyl) amino]benzoic acid Hispen Genesis P5.50/tab Tablet 500 mg For the relief of pain including muscular, rheumatic, traumatic, dental, post- op and post partum pain, headache, and juvenile rheumatic arthritis Category C OR Category D (in third trimester or near delivery) Afligec Filadams P6.20/caplet Caplet 500 mg Dolfenal Westmont P10.83/tab Tablet 250 mg P20.85/tab 500 mg Dolsten Medic+Aid P2.95/cap Capsule 250 mg P4.95/cap 500 mg Gisfen S V More P5.54/tab Tablet 500 mg Generic Name Structure IUPAC name Trade Name Manufacturer Selling Price Dosage Form/s Strengths Clinical Indication Pregnancy Category Tramadol
() cis-2- [(dimethylamino) methyl]-1-(3- Clomadol Mount Mettur P104.00/amp (1 mL) Ampule 50 mg/ mL Relief of p mild to moderate to Category C Dolotral Stada P17.58/cap Capsule 50 mg methoxyphenyl) cyclohexanol hydrochloride
P106.80/amp (2 mL) Ampule 100 mg/ 2 mL severe pain (chronic back pain, neuropathic pain, surgical pain, and pain associated with cancer or arthritis Tramid Euro-Med P84.00/amp (1 mL) Ampule 50 mg/ mL Pengesic Hovid P12.50/cap Capsule 50 mg Peptrad Shin Poong P52.00/amp (1 mL) Ampule 50 mg/ mL
ANTIDEPRESSANTS
Name Citalopram HBr Structure
IUPAC Name 5-Isobenzofurancarbonitrile 5 Trade Names 1. Feliz 20 Manufactured by Torrent Selling price: 3 10's (P1760.00/box) 2. Lupram Manufactured by Lundbeck Selling price: 14's (P1670.00/pack) 3. Celexa Manufactured by Forest Laboratories (US) Selling price: N/A 4. Cipramill Manufactured by Lundbeck (US) Selling price: N/A Dosage Forms & Strengths Tablets: 10, 20, and 40 mg Solution: 10 mg/5 ml Clinical Indication Depression in patients whose diagnosis corresponds most closely to the DSM-III and DSM-III-R category of major depressive disorder Pregnancy Category Pregnancy category: C Use late in the third trimester associated with complications in newborns and may require prolonged hospitalization, respiratory support, and tube feeding.
Name Escitalopram Structure
IUPAC Name (1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile 5 Trade Names 1. Nexito Manufactured by Jewim Pharma Selling price: 10mg 100s (P474.50/box) 2. Feliz S 10/ Feliz S 20 Manufactured by Torrent Pharma Selling price: Feliz s 10 100's (P3300.00/box) Feliz s 20 100s (P6000.00/box) 3. Jovia Manufactured by Medichem Selling price: 10mg 28's (P1188.21/pack) 4. Lexapro Manufactured by Lundbeck Selling price: 5mg 28's (P1650.00/pack) 10mg 14's (P1500.00/pack) 20mg 28's (P6000.00/pack) 5. Morcet Manufactured by Searle Selling price: 20mg 250s (P7553.00/pack) Dosage Forms & Strengths 5mg, 10mg, 20mg film coated tablets 5mg/5ml oral solution
Clinical Indication For major depressive disorder, generalized anxiety disorder, social anxiety disorder, obsessive-compulsive disorder, and panic disorder(significant behavioral change). Pregnancy Category Category C Use late in the third trimester associated with complications in newborns and may require prolonged hospitalization, respiratory support, and tube feeding.
Name Sertraline HCl Structure
IUPAC Name (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine 5 Trade Names 1. Exulten Manufactured by: Medichem Selling price: 30's (P1071.29/pack) 2. Serenata Manufactured by: Torrent Selling price: 30's (P1858.50/pack) 3. Zolodin Manufactured by: Medchoice Pharma Selling price: 30's (P38.00/tab, P1140.00/box) 4. Zoloft Manufactured by: Pfizer Selling price: 28's (P3717.78/pack) Dosage Forms & Strengths Tablet: 25mg, 50mg, 100mg Solution: 20mg/ml Clinical Indication Treatment of symptoms of depression, including depression accompanied by symptoms of anxiety, in patients w/ or w/o history of mania. Treatment of obsessive-compulsive disorder (OCD), ped OCD, panic disorder w/ or w/o agoraphobia, post traumatic stress disorder (PTSD), social phobia & premenstrual dysphoric disorder (PMDD). Pregnancy Category Category C or Category D (if taken in the 2nd half of pregnancy)
Name Fluoxetine HCl Structure
IUPAC Name N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine 5 Trade Names 1. Motivest Manufactured by: Medichem Pharmaceuticals, Inc. Selling price: 30s (P974.33/pack) 2. Neuxetin .Manufactured by: Korea United Pharma (Korea) Selling price: 30s (P1230.00/pack) 3. Prodin Manufactured by: MedChoice Pharma, Inc. Selling price: P38.00/cap, 30s (P1140.00/box) 4. Prozac 20 Manufactured by: Eli Lilly (USA) Selling price: P125.00/cap 5. Prozyn Manufactured by: Platinum Pharmaceuticals Ltd. (Pakistan) Selling price: 30s (P900.00/box) Dosage Forms & Strengths Capsule: 20mg Syrup: 20mg/5mL Clinical Indication Management of generalized anxiety disorder, obsessive compulsive disorder, panic disorders w/ or w/o agoraphobia, social phobia & posttraumatic stress disorder; bulimia nervosa. Treatment of premenstrual dysphoric disorder. Pregnancy Category Category C
2. Seroxat Manufactured by: GlaxoSmithKline (GSK) Selling price: 30s Php 1,792.80/ 3. Pexeva Manufactured by: Noven Pharmaceuticals, Inc. Selling price: N/A 4. Brisdelle Manufactured by: Noven Pharmaceuticals, Inc. Selling price: N/A 5. Panex Manufactured by: Brown & Burk Phils. Selling price: Php 79.02/tab Dosage Forms & Strengths Tablet: 10 mg, 20 mg, 30 mg & 40 mg Oral Suspension: 10mg/5mL Clinical Indication This medication is an SSRI antidepressant, prescribed for major depression, obsessive-compulsive disorder, panic disorder, social anxiety and generalized anxiety disorder. It increases the amount of serotonin, a natural substance in the brain that helps maintain mental balance. Pregnancy Category Pregnancy category: D Infants exposed to paroxetine in the first trimester of pregnancy have an increased risk of congenital malformations, particularly cardiovascular malformations.
ANTIHISTAMINES A. Name: Cetirizine diHCl Structure:
IUPAC name: ()-[2-[4-[(4-chlorophenyl)phenylmethyl]-1- piperazinyl]ethoxy]acetic acid Trade Name Manufacturer Selling Price Zyrtec Duncan Oral drops 10 mg/mL: 10 mL x 1's (P377.00/bottle) Oral solution 1 mg/mL: 30 mL x 1's (P205.00/bottle) 60 mL x 1's (P392.00/bottle) Tablet 10 mg: 100's (P3667.00/box) RiteMED Cetirizine RiteMED Tablet 10 mg: 100's (P2075.00/box, P20.75/tab) Virlix GlaxoSmithKline Film-coated tablet 10 mg: 50's (P2300.00/pack) Oral drops 10 mg/mL: 10 mL x 1's (P391.00/bottle) Oral solution 1 mg/mL: 30 mL x 1's (P221.80/bottle) Prixlae Shou Chan Film-coated tablet 10 mg: 100's (P2150.00/pack) Allerkid Pediatrica Oral drops 2.5 mg/mL: 10 mL x 1's (P142.00/bottle) Syrup 5 mg/5 mL: 30 mL x 1s (P130.00/bottle) 60 mL x 1s (P212.26/bottle)
Dosage Form and Strength: tablet 10 mg oral drops 10 mg/mL and 2.5 mg/mL oral solution 1 mg/mL syrup 5 mg/ 5 mL
Clinical Indication: Cetirizine diHCl is indicated for the relief of symptoms associated with perennial allergic rhinitis due to allergens such as dust mites, animal dander and molds in adults and children 6 months of age and older. Symptoms treated effectively include sneezing, rhinorrhea, postnasal discharge, nasal pruritus, ocular pruritus, and tearing. Cetirizine diHCl is also indicated for the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria in adults and children 6 months of age and older. It significantly reduces the occurrence, severity, and duration of hives and significantly reduces pruritus. Pregnancy Category: Category B: Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1 st trimester (and there is no evidence of a risk in later trimester). B. Name: Loratadine Structure:
Dosage Form and Strength: tab 10 mg syrup 5 mg/5mL
Clinical Indication: Loratadine is indicated for the relief of symptoms and signs of chronic urticaria sand other allergic dermatologic disorders. It is also used in the relief of symptoms associated with allergic rhinitis such as sneezing, nasal discharge and itching, and ocular itching and burning.
Pregnancy Category: Category B: Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1 st trimester (and there is no evidence of a risk in later trimester). C. Name: Fexofenadine HCl Structure:
Dosage Form and Strength: film-coated tablet 120 mg and 180mg Clinical Indication: Fexofenadine HCl is indicated for the symptomatic relief of allergic conditions including seasonal allergic rhinitis and chronic urticaria.
Pregnancy Category: Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) an there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus.
Trade name Manufacturer Selling price Benadryl AH Johnson & Johnson
Benadryl AH cap 25 mg 100's (P1663.00/pack) Source: MIMS Philippines Benadryl AH cap 50 mg 100's (P2810.50/pack) Source: MIMS Philippines Benadryl AH syrup 12.5 mg/5 mL 60 mL x 1's (P109.25/bottle) Source: MIMS Philippines 120 mL x 1s (P174.50/bottle) Source: MIMS Philippines Soniphen United Lab
Soniphen soft-gelatin cap 25 mg 100's (P1037.74/pack) Source: MIMS Philippines Soniphen syrup 12.5 mg/5 mL 60 mL x 1's (P59.44/bottle) Source: MIMS Philippines
Amherst Lab Soniphen cap 50 mg 30's (P339.62/box) Source: MIMS Philippines Soniphen inj 50 mg/mL 1 mL x 10's (P1038.20/ampoule) Source: MIMS Philippines
Dramelin Wescrib Dramelin cap 50 mg 100s (P263.00/pack) Source: MIMS Philippines Dramelin syrup 12.5mg/5mL 60 mL x 1's (P70.00/bottle) Source: MIMS Philippines RiteMed Diphenhydramine HCl
RiteMed RiteMed Diphenhydramine HCl cap 50 mg 100s (P700.00/pack) Source: Mercury Drug Store Bexil Zhejiang Ruixin Bexil inj 50 mg/mL 1 mL x 10 x 1's (P130.00/ampoule) Source: MIMS Philippines
Dosage Form and Strength: Capsule 25 mg Capsule 50 mg Syrup 12.5 mg/5 mL o 60 mL o 120 mL Injection 50 mg/mL
Clinical Indication: Antihistaminic: For perennial and seasonal (hay fever) allergic rhinitis; vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and foods; amelioration of allergic reactions to blood or plasma, dermatographism; as therapy for anaphylactic reactions adjunctive to epinephrine and other standard measures after the acute manifestations have been controlled. Motion Sickness: For active and prophylactic treatment of motion sickness. Antiparkinsonism: For parkinsonism (including drug-induced extrapyramidal reactions) in the elderly unable to tolerate more potent agents; mild cases of parkinsonism (including drug-induced) in other age groups; in other cases of parkinsonism (including drug-induced) in combination with centrally-acting anticholinergic agents.
Pregnancy Category: Category B: Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1 st trimester (and there is no evidence of a risk in later trimester). E. Name: Levocetirizine Structure:
Dosage Form and Strength: oral solution 2.5 mg/5mL tablet 5 mg
Clinical Indication: Levocetirizine is indicated for the symptomatic treatment of seasonal and perennial allergic rhinitis including persistent allergic rhinitis and chronic idiopathic urticarial.
Pregnancy Category: Category B: Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the 1 st trimester (and there is no evidence of a risk in later trimester).
The Link Between Nutrition and Dementia - Domenic Commisso MSc (Nutrition and Dietetics)., B HSc (Naturopathy)., Grad cert Nutrition Medicine (RMIT). Current Post Grad Student. https://imgv2-2-f.scribdassets.com/img/document/363803986/111x142/a2aa85527d/1510272183