Red Flags
Red Flags
Body region
Cervical
Diagnosis
Myelopathy
Fracture
Instability
Cervical Arterial
Dissection
Malignancy
Upper Extremity
Coronary Artery
Disease (CAD)
Elbow Fracture
Lumbo-pelvic
Fracture
Malignancy
Cauda Equina
Syndrome
Sx/Sy
CPR:
- Age > 45
- Gait abnormality
- + Babinski
- +Inverted Supinator
- +Hoffmans
Refer to Canadian C-spine
rules
Hx of trauma; RA, Down
Syndrome; signs of cord
compression
- + Sharp Pursor
- + Alar Ligament
- + Anterior Shear
- Age > 40
- Recent head/neck trauma
- Recent infection
- Migraines
CPR:
- Past hx of CA
- Age >50
- Recent unexplained weight
loss
- Failed conservative tx
CPR:
- Females > 65, males > 55
- Known clinical vascular
disease
- Pain worse during exercise
- Pain not reproducible by
palpation
- Patient believes pain is of
cardiac origin
- Elbow Extension Test
CPR:
- Age > 50
- Female gender
- Major trauma
- Pain and tenderness
- Distracting injury
- Pelvic palpation
CPR:
- Past hx of CA
- Age >50
- Recent unexplained weight
loss
- Failed conservative treatment
- Urinary Retention
- Bladder dysfunction
- Major limb motor
dysfunction
- Saddle anesthesia
Diagnostic Accuracy
1/5: Sn .94, Sp .31
2/5: Sn .39, Sp .88
3/5: Sn .19, Sp .99
4/5: Sn .09, Sp 1.0
(Cook, 2010)
Sn .9-1.0
(Michaleff, 2012)
No clustered statistics
published
Sharp Pursor: Sn .69, Sp
.96, +LR 17.3
(Forrester, 1999)
No published statistics
Sn .97, Sp .49
-LR: .03 (adults), .11
(children)
(Appelboam, 2008)
Unvalidated CPR
(Henschke, 2008)
No clustered statistics
published.
Urinary Retention: Sn .90,
Sp .95, +LR 18, -LR0.1
(Deyo, 1992)
Ankylosing
Spondylitis
Knee Fracture
Malignancy
Lower Extremity
CPR:
- Morning stiffness > 30
minutes
- Improvement with exercise
- Waking with back pain in the
second half of the night
- Alternating buttock pain
CPR:
- Age > 55
- Isolated patellar tenderness
- Isolated fibular head
tenderness
- Inability to actively flex knee
to 90 degrees
- Inability to bear weight x 4
steps immediately following
injury and in the ED
CPR:
- Past hx of CA
- Age >50
- Recent unexplained weight
loss
- Failed conservative treatment
Deep Vein
Thrombosis
Ankle/Foot Fracture
CPR:
- Isolated medial/lateral
malleolus, navicular, or base of
the 5th metatarsal bony
tenderness
- Inability to bear weight x 4
steps immediately following
injury and in the ED
References
1. Cook, C. Clustered clinical findings for diagnosis of cervical spine myelopathy.
2. Michaleff, Z. Accuracy of the Canadian C-spine rule and NEXUS to screen for clinically important cervical spine injury in patients
following blunt trauma: a systematic review.
3. Forrester, GA et al. Reliability and Validity of the Sharp-Purser Test in the Assessment of Atlanto-axial Instability in Patients with
Rheumatoid Arthritis. Physiotherapy, Volume 85 , Issue 7 , 376.
4. Deyo RA, Diehl AK. Cancer as a cause of back pain: frequency, clinical presentation, and diagnostic strategies. Journal of General
Internal Medicine 1988;3:2308.
5. Bsner S, Haasenritter J, Becker A, et al. Ruling out coronary artery disease in primary care: development and validation of a
simple prediction rule. CMAJ. 2010;182(2):1295-1300.
6. Appelboam A, Reuben A D, Benger J R, Beech F, Dutson J, Haig S et al. Elbow extension test to rule out elbow fracture:
multicentre, prospective validation and observational study of diagnostic accuracy in adults and children BMJ 2008; 337:a2428.
7. Henschke N. A systematic review identifies five "red flags" to screen for vertebral fracture in patients with low back pain.
8. Deyo RA, Rainville J, Kent DL. What can the history and physical examination tell us
about low back pain? JAMA 1992;268:7605.
9. McCormick, JP. Clinical effectiveness of the physical examination in diagnosis of posterior pelvic ring injuries.
10. Rudwaleit M, Metter A, Listing J, Sieper J, Braun J. Inflammatory back pain in ankylosing spondylitis. Arthritis Rheum.
2006;54;569-578.
11. Bachmann, LM. The accuracy of the Ottawa knee rule to rule out knee fractures: a systematic review.
12. Tagelagi M, Elley CR. Accuracy of the Wells Rule in diagnosing deep vein thrombosis in primary health care.
13. Steill IG. Decision rules for the use of radiography in acute ankle injuries. Refinement and prospective validation.