STD
STD
STD
INFECTIOUS
Herpes simplex
Syphilis
Condyloma
accumonata
Candida
INFLAMMATORY
Fixed drug
eruption
Balanitides
Proriasis
Contact dermatitis
Lichen planus
NEOPLASTIC
Squamous cell
carcinoma
Bowens disease
TRAUMATIC
Accident/ burns
Suction/vacuum
erection divice
Zipper entrapment
Sexual induced
Amateur
circumcision
ETIOLOGY
Herpes simplex
Chancroid
ETIOLOGY
Primary syphilis
(Chancre)
Lymphogranuloma
venereum
DIAGNOSIS
Treponema pallidum on
darkfield microscopy/direct
fluorescent or LN aspirate
+ve serologic non treponemal
testing
Definitive : Chlamydia
trachomatis on culture
LN aspirate +ve
immunofluorescence = Bodies
inclusion/+ve C.trachomatis
Granuloma inguinale
Definitive :
1. Intracytolasmic Donovan
bodie on Wright stain
2. +ve Giemsa stain
PATHOLOGIC
AL
Def: Acute infectious STD affects the epithelium
of lower urogenital system
Etio: Neisseria gonorrhea
MOT: Sexual contact [Homo,hetero,orogenital]
Asexual [Contaminated towel,hand]
IP : 2-5 days
CP: 1. Gonococcal ant Urethral discharge,
KyraKhali
d
1. Infectious
Sexually transm. urethritis -Chlamydia,
mycoplasma genitalium
Non sexual urethritis Bacterial + UTI,
schistommomiasis
2. Infected organ: Cystitis, Balanitis,
Prostatitis
INCUBATION PERIOD
2-5 days
9-90 days
7 days [3 days to 3 weeks]
9 -90 days
1-6 weeks
2-7 days
3-10 years
KyraKhali
d
SYPHILIS
1. Dark field microscopy
Bright, corkscrew-shaped
2. PCR
3. Tissue biopsy
4. Serological test
Reagin test [non-specific antibodies test]: Wasserman
reaction, Rapid Plasma Reagin Test
Trepomal test [specific] : Flourescent Treponemal
Antibody [FTA]
5. Others: CSF [>5% lymphocyte,> 40% protein]
CHANCROID
1. Direct smear stained with Grams stain
School of fish pattern
2. Direct immunofluorescent : Check antigen
3. Culture on specific media [aka beef infusion agar,
rabbits blood]
colonies of organisms
4. ELISA/PCR
GRANULOMA INGUINALE
1. Tissue Smear with Wrights/Giemsa/Grams stain
Closed safety-pin apprearance
2. PCR
Specimen collected
Tissue biopsy from the margin
of the lesion
LYMPHOGRANULOMA VENERUM
Causative organism
Chlamydia trachomatis
Specimen collected
Urethral exudate
Causative organism
Herpes simplex type 1, 2
Specimen collected
Scrapping of the lesion floor
KyraKhali
d
Causative organism
HIV 1 & 2
Specimen collected
Overall investigations
1. Dark microscopic exam 2. Serological test 3. Viral study 4. Biopsy
KyraKhali
d
OBJECTIVE 7: STD THAT CAN CROSS THE PLACENTA AND AFFECT THE FETUS
1. Bacterial STIs
Infection
Method of Transfer
Gonorrhea
Chlamydia
Trichomoniasis
Bacterial
Vaginosis
Syphilis
M Miscarriage
B Stillbirth, congenital syphilis which can
result in mental & physical problems
2. Viral STIs
Infection
Method of Transfer
Human
Papilloma
Virus (HPV)
Herpes
Human
Immunodeficiency
Virus (HIV)
KyraKhali
d