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    Joshua Christian Penggele
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    Sucralfate is a medication used to treat and prevent ulcers. It works by forming a protective paste on the ulcer that shields it from stomach acid. Common side effects include constipation, diarrhea and dizziness. It can interact with other drugs by decreasing their absorption. Nursing care involves monitoring for abdominal pain and blood in the stool. The goals are to reduce pain and promote ulcer healing.

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    Sucralfate is a medication used to treat and prevent ulcers. It works by forming a protective paste on the ulcer that shields it from stomach acid. Common side effects include constipation, diarrhea and dizziness. It can interact with other drugs by decreasing their absorption. Nursing care involves monitoring for abdominal pain and blood in the stool. The goals are to reduce pain and promote ulcer healing.

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    © All Rights Reserved
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    416 views2 pages

    Sucralfate PDF

    Uploaded by

    Joshua Christian Penggele
    Sucralfate is a medication used to treat and prevent ulcers. It works by forming a protective paste on the ulcer that shields it from stomach acid. Common side effects include constipation, diarrhea and dizziness. It can interact with other drugs by decreasing their absorption. Nursing care involves monitoring for abdominal pain and blood in the stool. The goals are to reduce pain and promote ulcer healing.

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    © All Rights Reserved
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    of 2

    Name /bks_53161_deglins_md_disk/sucralfate 02/17/2014 10:30AM Plate # 0-Composite pg 1 # 1

    1 Adverse Reactions/Side Effects


    CNS: dizziness, drowsiness. GI: constipation, diarrhea, dry mouth, gastric discom- PDF Page #1
    sucralfate (soo-kral-fate) fort, indigestion, nausea. Derm: pruritus, rashes. Endo: hyperglycemia (with sus-
    Carafate, Sulcrate pension). Misc: ANAPHYLAXIS.
    Classification Interactions
    Therapeutic: antiulcer agents Drug-Drug: Maypabsorption of phenytoin, fat-soluble vitamins, or tetracy-
    Pharmacologic: GI protectants cline.peffectiveness when used with antacids, cimetidine, or ranitidine.pab-
    Pregnancy Category B sorption of fluoroquinolones (separate administration by 2 hours).
    Route/Dosage
    Indications
    Short-term management of duodenal ulcers. Maintenance (preventive) therapy of Treatment of Ulcers
    duodenal ulcers. Unlabeled Use: Management of gastric ulcer or gastroesopha- PO (Adults): 1 g 4 times daily, given 1 hr before meals and at bedtime; or 2 g twice
    geal reflux. Prevention of gastric mucosal injury caused by high-dose aspirin or other daily, on waking and at bedtime.
    NSAIDs in patients with rheumatoid arthritis or in high-stress situations (e.g., inten-
    sive care unit). Suspension: Mucositis/stomatitis/rectal or oral ulcerations from Prevention of Ulcers
    various etiologies. PO (Adults): 1 g twice daily, given 1 hr before a meal.
    Action Gastroesophageal Reflux
    Aluminum salt of sulfated sucrose reacts with gastric acid to form a thick paste, which PO (Adults): 1 g 4 times daily, given 1 hr before meals and at bedtime (unlabeled).
    selectively adheres to the ulcer surface. Therapeutic Effects: Protection of ul- PO (Children): 40– 80 mg/kg/day divided q 6 hr, given 1 hr before meals and at
    cers, with subsequent healing. bedtime (unlabeled).
    Pharmacokinetics Stomatitis
    Absorption: Systemic absorption is minimal (⬍5%). PO (Adults and Children): 5– 10 mL of suspension swish and spit or swish and
    Distribution: Unknown. swallow 4 times daily.
    Metabolism and Excretion: ⬎90% is eliminated in the feces.
    Half-life: 6– 20 hr. Proctitis
    TIME/ACTION PROFILE (mucosal protectant effect) Rect (Adults): 2 g of suspension given as an enema once or twice daily.
    ROUTE ONSET PEAK DURATION NURSING IMPLICATIONS
    PO 1–2 hr unknown 6 hr Assessment
    ● Assess patient routinely for abdominal pain and frank or occult blood in the stool.
    Contraindications/Precautions
    Contraindicated in: Hypersensitivity. Potential Nursing Diagnoses
    Use Cautiously in: Renal failure (accumulation of aluminum can occur); Diabe- Acute pain (Indications)
    tes (qrisk of hyperglycemia with suspension); Impaired swallowing (qrisk of tablet Constipation (Side Effects)
    aspiration). Deficient knowledge, related to medication regimen (Patient/Family Teaching)
    ⫽ Canadian drug name. ⫽ Genetic Implication. CAPITALS indicate life-threatening, underlines indicate most frequent. Strikethrough ⫽ Discontinued.
    Name /bks_53161_deglins_md_disk/sucralfate 02/17/2014 10:30AM Plate # 0-Composite pg 2 # 2

    2
    Implementation PDF Page #2
    ● PO: Administer on an empty stomach, 1 hr before meals and at bedtime. Tablet
    may be broken or dissolved in water before ingestion. Shake suspension well be-
    fore administration.
    ● If nasogastric or feeding tube administration is required, consult pharmacist; pro-
    tein-binding properties of sucralfate have resulted in formation of a bezoar when
    administered with enteral feedings and other medications.
    ● If antacids are also required for pain, administer 30 min before or after sucralfate
    dosage.
    Patient/Family Teaching
    ● Advise patient to continue with course of therapy for 4– 8 wk, even if feeling better,
    to ensure ulcer healing. If a dose is missed, take as soon as remembered unless
    almost time for next dose; do not double doses.
    ● Advise patient that increase in fluid intake, dietary bulk, and exercise may prevent
    drug-induced constipation.
    ● Emphasize the importance of routine examinations to monitor progress.

    Evaluation/Desired Outcomes
    ● Decrease in abdominal pain.
    ● Prevention and healing of duodenal ulcers, seen by x-ray examination and endos-
    copy.
    Why was this drug prescribed for your patient?

    䉷 2015 F.A. Davis Company

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