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    Meraz Ahmed
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    Parotin is a preparation of paroxetine, a selective serotonin reuptake inhibitor. It is indicated for major depressive disorder, obsessive compulsive disorder, panic disorder, generalized anxiety disorder, and post-traumatic stress disorder. Common side effects include somnolence, insomnia, nausea, and sexual dysfunction. Parotin should be used cautiously in patients with certain medical conditions and avoids interactions with other drugs. It is available as 10mg and 20mg tablets in blister packs of 30 tablets.

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    Parotin is a preparation of paroxetine, a selective serotonin reuptake inhibitor. It is indicated for major depressive disorder, obsessive compulsive disorder, panic disorder, generalized anxiety disorder, and post-traumatic stress disorder. Common side effects include somnolence, insomnia, nausea, and sexual dysfunction. Parotin should be used cautiously in patients with certain medical conditions and avoids interactions with other drugs. It is available as 10mg and 20mg tablets in blister packs of 30 tablets.

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    © All Rights Reserved
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    25 views2 pages

    Parot in

    Uploaded by

    Meraz Ahmed
    Parotin is a preparation of paroxetine, a selective serotonin reuptake inhibitor. It is indicated for major depressive disorder, obsessive compulsive disorder, panic disorder, generalized anxiety disorder, and post-traumatic stress disorder. Common side effects include somnolence, insomnia, nausea, and sexual dysfunction. Parotin should be used cautiously in patients with certain medical conditions and avoids interactions with other drugs. It is available as 10mg and 20mg tablets in blister packs of 30 tablets.

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    © All Rights Reserved
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    Only for the use of medical professionals

    Parotin®
    Paroxetine

    Description
    Parotin® is a preparation of Paroxetine which is a potent and selective inhibitor of 5-
    hydroxytryptamine (5-HT, serotonin) uptake. Paroxetine works by enhancing the
    serotonergic activity in the central nervous system resulting from inhibition of neuronal
    reuptake of serotonin (5-hydroxytryptamine, 5-HT), in addition with blocking the reuptake
    of serotonin into human platelets and has only very weak effects on norepinephrine and
    dopamine neuronal reuptake.

    Indication and usage


    Parotin® is indicated for -
    Major depressive disorder ● Obsessive compulsive disorder
    Panic disorder ● Generalized anxiety disorder
    Social anxiety disorder ● Post-traumatic stress disorder

    Dosage and administration

    Adults
    ● Major depression, social anxiety disorder, post-traumatic stress disorder, generalized
    anxiety disorder: The recommended dose is 20mg daily, usually to be taken in the morning
    and maximum dose up to 50mg daily.

    ● Obsessive-compulsive disorder: The initial dose is 20mg daily, usually to be taken in the
    morning and maximum dose up to 60mg daily.

    ● Panic disorder: The initial dose is 10mg daily, usually to be taken in the morning and
    maximum dose up to 60mg daily.

    Elderly
    The maximum dose for elderly is 40mg daily.

    Children under 18 years


    Paroxetine is not recommended.

    Use in pregnancy and lactation


    Paroxetine should only be used during pregnancy when strictly indicated. Abrupt
    discontinuation should be avoided during pregnancy. Neonates should be observed if
    maternal use of paroxetine continues into the later stages of pregnancy, particularly the
    third trimester.

    Small amount of Paroxetine are excreted into breast milk and caution should be exercised
    when Paroxetine is administered to a nursing woman. In published studies, as no sign of
    drug effects were observed in infants, breast-feeding can be considered.
    Side effects
    The most common side effects are somnolence, insomnia, agitation, abnormal dreams
    (including nightmares), increases in cholesterol levels, decreased appetite, dizziness,
    tremor, headache, blurred vision, yawning, nausea, constipation, diarrhea, vomiting, dry
    mouth, sweating, sexual dysfunction, asthenia, body weight gain.

    The less common side effects are arrhythmias, confusion, urinary incontinence, panic
    attacks, depersonalization, neuroleptic malignant syndrome-like events, peripheral edema,
    acute glaucoma, hepatic disorders, priapism, tinnitus, extra pyramidal reactions and
    withdrawal reactions.

    Precautions
    Paroxetine should be used with caution in patients with mania, epilepsy, seizures, bone
    fracture, diabetes, ECT, glaucoma, cardiac conditions, hyponatraemia, haemorrhage,
    renal/hepatic impairment.

    Contraindications
    Paroxetine is contraindicated in patients with a hypersensitivity to Paroxetine or any of the
    exipients.

    Drug interactions
    Paroxetine should not be used with pimozide, tyrptophan, drug metabolizing enzyme
    inducers /inhibitors, thioridazine, alcohol, fosamprenavir/ritonavir, MAOIs, lithium,
    phenytoin/anticonvulsants, warfarin, drugs affecting gastric pH, NSAIDs and acetylsalicylic
    acid.

    Pharmaceutical precautions
    Keep away from the reach of children. Store in a cool and dry place protected from light. To
    be taken and sold only on the prescription of a registered physician.

    Presentation
    Parotin® 10 tablet: Each tablet contains Paroxetine 10mg as Hydrochloride Hemihydrate BP.
    Parotin® 20 tablet: Each tablet contains Paroxetine 20mg as Hydrochloride Hemihydrate BP.

    Packaging
    Parotin® 10 tablet: Carton of 30 tablets in blister pack.
    Parotin® 20 tablet: Carton of 30 tablets in blister pack.

    ® Registered Trade Mark

    ACI Limited
    Narayanganj, Bangladesh

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