Medical Technology Board Exam Reviewer 1: CLINICAL CHEMISTRY

1. Specimen collection and processing is under 8. The independent variable is plotted along the:
which part of the quality assurance program? a. Horizontal axis
a. Pre-analytical b. Vertical axis
b. Analytical c. Y-axis
c. Post-analytical d. Ordinate
d. None of the above
9. A value of 11.2 mg/dL thyroxine is equivalent
2. Mechanical hazards are caused by: to ___ in SI units.
a. Centrifuges a. 135 nmol/L
b. Refrigerators b. 135 mmol/L
c. Both c. 145 nmol/L
d. Neither d. 145 mmol/L

3. What kind of quality control is important in 10. Convert 4.5 g/dL albumin to SI units:
maintaining long term accuracy of the analytical a. 45 g/L
methods? b. 90 g/L
a. Internal quality control c. 0.45 g/L
b. External quality control d. 0.45 g/L
c. Sensitivity
d. Specificity 11. What is the conversion for bilirubin from
conventional (mg/dL) to SI (mmol/L) unit?
4. In statistics, this is used to determine whether a. 17.1
there is a statistically significant difference b. 0.357
between the standard deviations of two groups c. 88.4
of data. d. 0.0113
a. Mean
b. Median 12. What anticoagulant is used for cardiopulmonary
c. F-test bypass?
d. T-test a. EDTA
b. Heparin
5. It is a sample of known quantity with several c. Citrate
analytes present. d. Oxalate
a. Calibrator
b. Reagent 13. Glucose is metabolized at room temperature at a
c. Standard rate of ___ mg/dl/hour and at 4oC, the loss is
d. Control approximately ___ mg/dl/hour.
a. 2, 7 c. 8, 3
6. This is the most widely used quality control b. 3, 8 d. 7, 2
chart in the clinical laboratory.
a. Gaussian Curve 14. Whole blood fasting glucose level is ___ than in
b. Cumulative Sum Graph serum or plasma.
c. Youden/Twin Plot a. 10-15% lower
d. Levey-Jennings Chart b. 5-10% lower
c. 10-15% higher
7. This type of error which can be observed on a d. 5-10% higher
Levey-Jennings chart is formed control values
that distribute themselves on one side or either 15. The glycated hemoglobin value represents the
side of the mean for six consecutive days. blood glucose value during the preceding:
a. Trend a. One to three weeks
b. Shift b. Three to six weeks
c. Outliers c. Two to three weeks
d. None of the above d. Eight to twelve weeks
 Medical Technology Board Exam Reviewer 1: CLINICAL CHEMISTRY

16. Apolipoprotein B-100 is the primary component 23. Which method for the assay of uric acid is
of: simple and nonspecific?
a. VLDL a. Colorimetric: kinetic
b. LDL b. Colorimetric: end point
c. IDL c. Enzymatic: UV
d. HDL d. Enzymatic: H2O2

17. Intermediate density lipoprotein (IDL) and 24. This approach to the assay for urea nitrogen has
Lipoprotein a (are) considered as: a greater specificity and more expensive.
a. Major lipoproteins a. Colorimetric: diacetyl
b. Minor lipoproteins b. Caraway
c. Abnormal lipoproteins c. Kinetic
d. Fatty acids d. Enzymatic: NH3 formation

18. What age group has a moderate risk cut off 25. The most simple method for creatinine
value of >240 mg/dl and high risk cut off value determination but is nonspecific is:
of >260 mg/dl for total cholesterol? a. Colorimetric: end point
a. 2-19 years old b. Colorimetric: kinetic
b. 20-29 years old c. Enzymatic: UV
c. 30-39 years old d. Enzymatic: H2O2
d. 40 years old and over
26. Proteins that migrate in the alpha-2 globulin
19. According to the NCEP Guidelines for band in serum protein electrophoresis except:
Acceptable Measurement Error, the coefficient a. Transferring
of variation for HDL cholesterol should be on b. Haptoglobin
what range? c. AMG
a. < 2% d. Ceruloplasmin
b. < 3%
c. < 4% 27. This condition shows a beta-gamma bridging
d. < 5% effects as the serum protein electrophoretic
pattern:
20. This is considered as a one-step method for a. Multiple myeloma
cholesterol determination: b. Nephrotic syndrome
a. Liebermann-Burchardt c. Hepatic cirrhosis
b. Abell-Kendall d. Pulmonary emphysema
c. Schoenheimer Sperry
d. Bloors 28. In hemolytic disease of the newborn, which
form of bilirubin is elevated in plasma?
21. Cholesterol esterase is used in which method/s a. Conjugated bilirubin
for chelesterol determination? b. Unconjugated bilirubin
a. Chemical methods c. Delta bilirubin
b. Enzymatic methods d. B and C

22. LDL can be calculated from measurements of 29. Creatine kinase is under what enzyme category?
the following except: ___ by the Friedewald a. Oxidoreductases
formula: b. Hydrolases
a. Total cholesterol c. Lyases
b. VLDL d. Transferases
c. HDL
d. Triglyceride
 Medical Technology Board Exam Reviewer 1: CLINICAL CHEMISTRY

30. It is the only enzyme whose clinical significance 38. Which of the following drugs is a barbiturate?
is not increased, but decreased levels. a. Cyclosporine
a. Pseudocholinesterase b. Methotrexate
b. Ceruloplasmin c. Phenobarbital
c. 5’ Nucleotidase d. Acetaminophen
d. Glucose-6-Phospate Dehydrogenase
39. The signs and symptoms of this blood alcohol
31. For each degree of fever in the patient, pO2 will level in %w/v are mental confusion, dizziness
fall ___ & pCO2 will rise ___%. and strongly impaired motor skills (staggering,
a. 7,3 slurred speech).
b. 3,7 a. 0.09-0.25
c. 2,5 b. 0.18-0.30
d. 5,2 c. 0.27-0.40
d. 0.35-0.50
32. Confirmatory test for acromegaly:
a. Physical activity test 40. This pipette, commonly used in laboratories, is
b. Insulin tolerance test the considered the most basic pipette.
c. Somatomedin C a. Automatic pipette
d. Glucose suppression test b. Air displacement pipette
c. Glass pipette
33. It is the most potent of the estrogens. d. Positive displacement pipette
a. Estriol
b. Estrone 41. The BMI of an obese individual in kg/m2 is:
c. Estradiol a. 18.5
d. Testradiol b. 25
c. 29.9
34. An individual with hyperthyroidism will d. 30
manifest ___ triglyceride levels.
a. Increased 42. Which of the following is true about Fahey and
b. Decreased McKelvey method?
a. Kinetic method
35. An individual with hypothyroidism will b. Measured after 18 hours
manifest ___ T3 uptake levels. c. Diameter = log of concentration
a. Increased d. All of the above
b. Decreased
43. Which correctly describes when there is
36. This tumor marker is helpful in the diagnosis of damaged in the epithelium?
urinary bladder cancer: a. Increased AST
a. CA 19-9 b. Increased ALT
b. Calcitonin c. Direct bilirubin ratio to total bilirubin is greater
c. HER-2/neu than 1:2
d. NMP d. Increased CK

37. The primary product of hepatic metabolism of 44. Which correctly describes when there is
cocaine is: decreased in the potency of the biliary
a. Morphine epithelium?
b. NAPA a. Increased AST
c. Benzoylecgonine b. Increased ALT
d. Primidone c. Direct bilirubin ratio to total bilirubin is greater
than 1:2
d. Increased CK
 Medical Technology Board Exam Reviewer 1: CLINICAL CHEMISTRY

45. Which test are routinely used to assess the

46. Which enzyme has a moderate specificity for

47. Who can perform POCT for glucose?

48. Considered as the risk factor for coronary heart

49. Physician asks in asymptomatic DM patients