DLL On Changes in Chromosome Number

EXEMPLAR SCIENCE LESSON PLAN
GRADE LEVEL QUARTER / DOMAIN WEEK & DAY NO. PAGE NO.
GRADE 10 3rd QUARTER/LIVING THINGS WEEK 5 DAY2 1
AND THEIR ENVIRONMENT
I. OBJECTIVES
The learners demonstrate an understanding of:
1. The information stored in DNA as being used to make proteins
A. Content Standards
2. How changes in a DNA molecule may cause changes in its product
3. Mutations that occur in sex cells as being heritable
The learners shall be able to:
Option 1. Demonstrate the process of protein synthesis through role-playing.
Option 2. Explain the importance DNA as the code of life by creating a fictitious
B. Performance organism.
Standards Option 3: Compose a letter to the parents of the patients explaining their findings in
the Karyotyping activity.
Option 4. Interview parents in the community having children with genetic
Disorder.
C. Learning Explain how mutations may cause changes in the structure and function of a protein.
Competencies/ (S10LT-IIIe-38)
Objectives Write 1. Identify human disorders associated with aneuploidy
the LC code for 2. Create a display board showing the karyotype and important facts about the
each person with genetic disorder
II. CONTENT Heredity: Inheritance and Variation (Changes in Chromosome Number)
III. LEARNING RESOURCES
A. References
1. Teacher’s Guide
Teacher’s Guide pp. 210 - 212
pages
2. Learner’s Materials
Learner’s Material pp. 283-293
pages
3. Textbook pages
4. Additional Materials
from Learning
EASE/OHSP Biology Module 14: Genetics - The Study of Inherited Traits
Resource (LR)
portal
Accessed October 25, 2018. http://www.genetics.edu.au/genetics/Genetic-conditions-
support-groups/FS29.pdf.
Accessed October 25, 2018. . http://www.genetics.edu.au/genetics/Genetic-conditions-

support-groups/FS30.pdf.
B. Other Learning Accessed October 25, 2018. http://plaza.ufl.edu/brownjc/Sex-Chromosome-Linked

Resources Disorders homework.pdf.
Accessed October 25, 2018. http://www.genetics.edu.au/publications-and-

resources/facts-sheets/fact-sheet-36-trisomy-21-down-syndrome.
Accessed October 25, 2018. . http://www.ssbp.org.uk/XYY Syndrome.pdf.

Accessed October 25, 2018. http://www.genetics.edu.au/genetics/Publications and

Resources/Genetics-Fact-Sheets/FS32KBS.pdf.
IV. PROCEDURES
Entry Card: 3-2-1
A. Reviewing previous
3 types of Mutation
lesson or
2 causes of mutation
presenting the new
lesson 1 effect of mutaion
Have learners label the Genes, Chromosomes and DNA in the diagram/cartoon below:
B. Establishing a
purpose for the
lesson
Present a normal human karyotype
C. Presenting
examples/instances
of the new lesson
QUESTIONS:
1. What is the purpose of a karyotype? What information does it tell you?
2. How is karyotyping done?
3. Is this karyotype for a male or female? How can you tell?

4. Does this karyotype have the correct total number of chromosomes and chromosome
pairs?
3. Since we are dealing with human karyotypes, how many matched pairs of chromosomes
would you expect to see for a female? For a male?
GROUP ACTIVITY: HUMAN KARYOTYPING

Teacher Tasks: 1. Divide the class into 6 groups.
2. Hand out envelopes with cut karyotypes to each group. Tell
them, “We have been studying the genetics of plants, but
we’ll be looking at humans today. Today you will play the
D. Discussing new
role of a geneticist.
concepts and
Learners Tasks:
practicing new
skills #1 1. Match the chromosomes in your envelope and order them by size. The
longest chromosome is called number 1 and the shortest is called number 22.
The last pair of chromosomes is the sex chromosomes.
2. Glue your karyotypes to a clean sheet of paper.
3. Analyze and compare the karyotype made by your group with the karyotype
of a normal person. Write your observations in the worksheet.
GALLERY WALK
Post the Disorder Fact Sheets on the walls of the classroom. Have learners do the gallery
walk and ask them to gather the following information related to the patient’s karyotype
E. Discussing new
assigned to their respective groups. Have them write the facts on their activity sheets:
concepts and
1. Number of Chromosomes
practicing new
skills #2 2. What is the sex of the patient?
3. Patient’s genetic disorder
4. Reason for abnormality
5. Signs/symptoms
Have learners study the diagram of meiosis showing gametes formation
F. Developing
mastery (leads to
Formative
Assessment 3)
QUESTIONS:
1. What happens when chromosomes fail to separate before Meiosis ends?
2. How does nondisjunction change the number of chromosomes of
organisms/humans?
G. Finding practical
Ask learners if they know someone in their community suffering from any disorders
applications of
discussed in the lesson. Have them share how she/he interacts with normal persons in the
concepts and skills
in daily living community.
Have one representative from each group to fill in data needed in the table .
H. Making
generalizations and
abstractions about
the lesson
Assessment of group’s output using Rubrics

I. Evaluating learning Using recycled materials, have learners make a display of the karyotype and facts about
the genetic disorder assigned to their respective groups.
J. Additional activities
for application or Have learners prepare to present their display board next meeting
remediation
V. REMARKS
VI. REFLECTION
A. No. of learners who earned 80% in the evaluation
B. No. of learners who require additional activities for
remediation
C. Did the remedial lessons work? No. of learners who have
caught up with the lesson
D. No. of learners who continue to require remediation
E. Which of my teaching strategies worked well? Why did these
work?
F. What difficulties did I encounter which my principal or
supervisor can help me solve?
G. What innovation or localized materials did I use/discover
which I wish to share with other teachers?
ODETTE M. FABON
Writer/s: City of Mandaluyong Science High School
Mandaluyong

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EXEMPLAR SCIENCE LESSON PLAN

Accessed October 25, 2018. . http://www.genetics.edu.au/genetics/Genetic-conditions-

B. Other Learning Accessed October 25, 2018. http://plaza.ufl.edu/brownjc/Sex-Chromosome-Linked

Accessed October 25, 2018. http://www.genetics.edu.au/publications-and-

Accessed October 25, 2018. . http://www.ssbp.org.uk/XYY Syndrome.pdf.

Accessed October 25, 2018. http://www.genetics.edu.au/genetics/Publications and

Present a normal human karyotype

3. Is this karyotype for a male or female? How can you tell?

GROUP ACTIVITY: HUMAN KARYOTYPING

Assessment of group’s output using Rubrics

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