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    24 views3 pages

    Piperacillin

    Uploaded by

    Nicholas Tagle

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as docx, pdf, or txt
    of 3

    DRUG STUDY

    GENERIC NAME: Piperacillin / Tazobactam


    Brand name: Zosyn
    Drug Classification: Antiinfective; Beta-lactam antibiotic; Anti-pseudomonal penicillin

    DOSAGE, ROUTE, SIDE EFFECTS and


    FREQUENCY (prescribed and INDICATION MECHANISM OF ADVERSE REACTIONS
    recommended) ACTION (by system)
    It is similar to that of other
    penicillins. Interfere with Treatment of moderate to severe CNS: headache, insomnia, fever
    bacterial cell wall synthesis appendicitis, uncomplicated and
    promotes loss of membrane complicated skin and skin GI: diarrhea, nausea,
    integrity and leads to death structure infections, nosocomial or constipation, vomiting,
    of the organism. community-acquired pneumonia pseudomembranous colitis
    caused piperacillin-resistant,
    piperacillin/tazobactam SKIN: hypersensitivity reactions
    susceptible, beta-lactamase- ,rash, pruritus
    producing bacteria.

    NURSING RESPONSIBILITIES
    CONTRAINDICATION/S (at least 10)
    Hypersensitivity to penicillins, Before:
    cephalosphorins, or other drugs. > check the doctor’s order
    Safety in children < 12 years old, > assess for history: hepatic and renal impairment, lactation, pregnancy
    pregnancy, lactation.
    > assess for physical cues: skin status, LFTs, renal function tests, culture of
    affected area
    - > Obtain specimen for culture and sensitivity prior to first dose of the drug; start
    drug pending results. Periodic CBC with differential, platelet count, Hgb & Hgt, and
    serum electrolytes.

    During:
    > administer the right drug
    > explain to the patient about the importance and purpose of the drug
    > administer at the right time and right dosage
    > avoid alcohol while taking this drug and for 3 days after because severe
    reactions often occur
    > discontinue if hypersensitivity reaction occurs

    After:
    > document and record.
    - >Monitor for hypersensitivity response; discontinue drug and notify physician if allergic response
    noted.
    - Monitor for hemorrhagic manifestations because high dose may induce coagulation abnormalities.
    - Instruct family/significant others to report significant, unexplained diarrhea.

    Patient’s Name / Room No.

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