Clinical Infectious Diseases 2020
Clinical Infectious Diseases 2020
Clinical Infectious Diseases 2020
BRIEF REPORT
COVID-19 Transmission Within a Index 2 and cases 1–4 were all admitted to hospital as per-
sons under investigation on the day index 1’s diagnosis was con-
Family Cluster by Presymptomatic firmed. The daughter (case 1) presented with fever and cough
Carriers in China on 27 January, and was diagnosed with COVID-19 after being
tested positive by RT-PCR using throat swab specimen.
Received 11 March 2020; editorial decision 14 March 2020; accepted 20 March 2020;
published online March 23, 2020. main undiagnosed and be able to spread the disease to large
a
G. Q. and N. Y. contributed equally to this work.
numbers of people. Last, it appears that children may not be
Correspondence: X. Chen, Department of General Internal Medicine, Ningbo First Hospital,
No. 59 Liuting St, Haishu District, Ningbo, Zhejiang Province, China ([email protected]). as susceptible to this new virus as adults and elderly persons,
Clinical Infectious Diseases® 2020;XX(XX):1–2 and they may fare better when they have contracted the virus.
© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases As reported in this family cluster, the 6-year-old child was
Society of America. This is an Open Access article distributed under the terms of the Creative
Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/ not infected and the 13-month-old was infected but stayed
by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any asymptomatic.
medium, provided the original work is not altered or transformed in any way, and that the work
is properly cited. For commercial re-use, please contact [email protected]
In summary, there are variations across individuals in the
DOI: 10.1093/cid/ciaa316 clinical manifestations of COVID-19, indicating that we should
BRIEF REPORT • cid 2020:XX (XX XXXX) • 1
Downloaded from https://academic.oup.com/cid/article-abstract/doi/10.1093/cid/ciaa316/5810900 by Joongbu University user on 18 April 2020
Figure 1. Timeline of exposure to index patients with coronavirus disease 2019 (COVID-19) in China. Abbreviations: F, female; ICU, intensive care unit; M, male; PCR,
polymerase chain reaction.
pay attention to how to prevent people from being infected by Financial support. This work was supported by the Natural Science
Foundation of Zhejiang Province (grant number Q17H010001).
asymptomatic patients and patients who are in the incubation
Potential conflicts of interest. The authors: No reported conflicts of
period. interest. All authors have submitted the ICMJE Form for Disclosure of
Potential Conflicts of Interest.
Notes
Author contributions. L. W. and Xue. C. collected the data. Xiao C.,
References
G. Q., and N. Y. conceived the idea. G. Q. and N. Y. drafted the manuscript.
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Acknowledgments. The study has been reviewed and approved by the with the 2019 novel coronavirus indicating person-to-person transmission: a
Ningbo City First Hospital, Medical Ethical Committees (2020-R018). study of a family cluster. Lancet 2020. doi:10.1016/S0140-6736(20)30154–9.
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