Better outcomes with

D-2795-2019
non-invasive ventilation (NIV)
Non-invasive ventilation (NIV) is any form of ventilator support applied to patients
without the use of an endotracheal tube. Therefore, potential complications of invasive
mechanical ventilation can be avoided. It has been applied to many different patients
with acute and chronic respiratory failure and is also used to support weaning therapy.

© Drägerwerk AG & Co. KGaA 1

BETTER OUTCOMES WITH NON-INVASIVE VENTILATION (NIV) BETTER OUTCOMES WITH NON-INVASIVE VENTILATION (NIV)

“Patients with mechanically-assisted ventilation often develop ventilator- Non-invasive ventilation (NIV)
associated-pneumonia which potentially lead to a longer hospital stay.”1
ONE DEVICE FOR INVASIVE AND NON-INVASIVE THERAPY INTELLIGENT ALARMS AND PARAMETER ADAPTATIONS
This approach simplifies the continuous implementation of an When non-invasive ventilation is chosen, alarms that are not
“Oversedation during mechanically-assisted ventilation is associated with optimal ventilation strategy. The NIV option means that non- applicable will not be displayed. In order to avoid artefacts, var-
worse clinical outcomes, including longer time on mechanical ventilation, invasive ventilation can be applied … ious alarm settings may be deactivated (e.g.: MVe, Vti high and
Apnea monitoring). For improved patient safety, a clearly visible
and increased brain dysfunction.”2 - in all ventilation modes* displayed message alerts the user to any deactivated alarms.
- with comprehensive monitoring
- with alarm adaptation SENSITIVE LEAKAGE COMPENSATION
“Complications from intubation can have significant morbidity and - with automatic leak compensation Leak compensation is an essential part of NIV therapy. With
mortality risks.”3 leakage compensation the flow-trigger sensitivity is adjusted
You can start with NIV whenever the patient is ready for it, according to leak size. In volume-controlled modes, the patient
without the need to change devices. Should intubation be nec- always receives the set tidal volume. In pressure-controlled
essary the therapist can quickly and easily switch to an invasive modes, the set pressure levels are continuously maintained.
ventilation mode. Even in the presence of large leaks, our ventilators flexible leak
Prevent intubation as long as possible and secure the weaning in the recovery phase compensation system continuously provides the exact amount
PREVENT AND SHORTEN INTUBATION TIME of breathing gas needed to complement the patient’s flow de-
Intubation has been linked to an increased risk for the develop- mand.
ment of ventilator-associated pneumonia2 , weaning problems
and patient discomfort. Due to these risks, both intubation and ANTI-AIR-SHOWER
invasive ventilation should be avoided whenever possible. NIV In case the mask has been taken off the Anti-Air-Shower func-
helps to avoid re-intubation and shorten recovery times1,4. The tion detects this disconnection and reduces the device given
use of NIV has been expanded to intensive care applications, high flow (e.g. for leakage compensation) to a minimum level.
including the treatment of acute chronic respiratory failure.3 It is This may help to reduce a possible contamination of caregivers
PREVENT WEAN QUICK SECURE WEANING an excellent choice for intermittent application when partial re- and ambient air. Accordingly, reconnection is detected and ven-
NON-INVASIVE INTUBATION
PROTECT THE LUNG
AND SAFE SUCCESS
VENTILATION spiratory support is needed. NIV applied as a weaning method tilation will continue automatically with the previous settings.
in COPD enables faster weaning and has a positive effect on
EARLY INTUBATION INTUBATION REINTUBATION
mortality rates.5
RISK OF VAP
RISK OF EXTUBATION
INVASIVE FAILURE
VENTILATION RISK OF VALI, ARDS RISK OF WEANING
FAILURE

D-12306-2016
NIV with the Evita V800 NIV with the Savina 300

MECHANICAL VENTILATION
As non-invasive as possible, as invasive as necessary. Along the Respiration Pathway a variance and diversity of treatment
WHAT IS NIV? Ventilation), is also very often referred to as “mask ventilation”.
tools clearly improve the clinical decision-making.
NIV – non-invasive ventilation is a broad term for any ventilation This is in contrast to “invasive ventilation”, where an endotracheal
NIV with automatic leak compensation in all ventilation modes supports the seamless transition from one application mode therapy applied in a non-invasive way, e.g. via a mask or nasal tube or a tracheal canula serves as an invasive interface between
to another supporting minimal invasiveness. prongs. Therefore, NIV, or NPPV (Non-invasive Positive Pressure the patient and the ventilator.

1 Kalanuria A, Zai W, Mirski M. Ventilator-associated pneumonia in the ICU. Crit Care (2014) 18: 208. https://doi.org/10.1186/cc13775
2 Hughes CG, McGrane S, Pandharipande PP. Sedation in the intensive care setting. Clin Pharmacol. 2012; 4: 53–63
3 Loh KS, Irish JC. Traumatic complications of intubation and other airway management procedures. Anesthesiology Clinics of North America [01 Dec 2002, 20(4):953-969] *In neonatal ventilation only in SPN-CPAP and PC-CMV
1 Ferrer M, et al. Noninvasive ventilation in severe hypoxemic respiratory failure: a randomized clinical trial. Am J Respir Crit Care Med Vol 168. pp 1438–1444, 2003
2 2 Collard HR, Saint S, Matthay MA. Prevention of ventilator-associated pneumonia. Ann Intern Med. 2003 Mar 18;138(6):494-501 © Drägerwerk AG & Co. KGaA 3
3 Becker H F, Schönhofer B, Burchardi H. Nicht invasive Beatmung. Vorwort, S 59; Thieme 2005
4 Ram FSF et al. Non-invasive positive pressure ventilation for treatment of respiratory failure due to exacerbations of chronic obstructive pulmonary disease. The Cochrane Library 2005, Issue 4
5 Nava S, Ambrosio N, Clini E, et al. Noninvasive Mechanical Ventilation in the Weaning of Patients with Respiratory Failure Due to Chronic Obstructive Pulmonary Disease. Ann Intern Med. 128: 721 – 728; 1998
 BETTER OUTCOMES WITH NON-INVASIVE VENTILATION (NIV) BETTER OUTCOMES WITH NON-INVASIVE VENTILATION (NIV)

How rotation strategies can improve NIV tolerance

Improved outcomes have been shown with NIV
Non-invasive respiratory support encompasses CPAP.  Positive treatment when  treating acute  respiratory failure. Furthermore,
pressure respiratory support is delivered by utilising an external selecting the correct type of interface greatly reduces painful skin
interface such as a Nasal mask, Oronasal mask, or Total-Face breakdown and ulcerations. Thus, an alternating interface strategy
mask. Two key factors involved in successful NIV treatment are not only reduces the points of highest pressure, but also improves
the  rotation of the  mask type  and  choice of interface. Studies NIV tolerance and efficacy. We work together with you to find the ”NIV leads to a reduced number of complications
have  proven that alternating different mask types, from nasal to best rotation strategies, both for mask and interface types, to pro- by 62 % and treatment errors by 50%.“ 1
oronasal or Total-Face masks, improves the effectiveness of  mote your patient’s comfort.7,8

”Early NIV reduces the need for intubation

by 59 %.“ 2,3

”NIV leads to a shorter stay on the ICU and a

D-28635-2015

D-10386-2016

D-42721-2015
D-2300-2011

reduced length of hospital stay by average of 3 days.“ 4

Full-face mask NovaStar® plus* ClassicStar® NIV total-face mask ClassicStar® plus nasal mask* ClassicStar® plus NIV oronasal
mask*

”The mortality rate for COPD patients using

non-invasive ventilation falls by 48 %.“ 3

”NIV increases the quality of life for patients.“ 1,5,6

1  Ferrer M, et al. Non-invasive Ventilation during Persistent Weaning Failure. Am. J. Respir. Crit. Care Med. 2003
2  Elliott MW. Non-invasive ventilation for acute respiratory disease. British Medical Bulletin 2004
3 Ram FSF et al. Non-invasive positive pressure ventilation for treatment of respiratory failure due to
exacerbations of chronic obstructive pulmonary disease. The Cochrane Database of Systematic Reviews 2004
4 Warren DK, et al. Outcome and attributable cost of ventilator-associated pneumonia among intensive care unit
patients in a suburban medical center. Crit Care Med. 2003
5 Nava S, et al. Time of non-invasive ventilation. Intensive Care Med. 2006 Mar
6  Bülow HH, et al. Experiences from introducing non-invasive ventilation in the intensive care unit: a 2-year
prospective consecutive cohort study. Acta Anaesthesiol Scand 2007

*not available in the US

7 Hilbert G, Gruson D, Gbikpi-Benissan G, Cardinaud JP. Sequential use of noninvasive pressure support ventilation for acute exacerbations of COPD. Intensive Care Med. 1997;23:955–961.
8 Ozyilmaz E et al. Timing of noninvasive ventilation failure: causes, risk factors, and potential remedies. BMC Pulm. Med. 2014; 14:19

4 © Drägerwerk AG & Co. KGaA 5

BETTER OUTCOMES WITH NON-INVASIVE VENTILATION (NIV)

NIV IS AVAILABLE FOR THE FOLLOWING DRÄGER ICU VENTILATORS:

- Evita® V800
- Evita® V600
- Evita® Infinity® V500
- Evita® V300
- Savina® 300 Select
- Savina® 300 Classic

D-5759-2018
Dräger Evita® V800
Not all products or features are for sale in all countries or are only available as an option.

TECHNICAL DATA EVITA V-SERIES TECHNICAL DATA SAVINA 300

91 08 147 | 19.11-1 | CR | LE | Subject to modifications | © 2019 Drägerwerk AG & Co. KGaA

Option NIV alarms Option NIV alarms
MVe 0.01 ... 40 L/min or off MV low 0.2 ... 40 L/min or off
VTi high 0.110 ... 4 L or off VTi high 0.06 ... 4 L or off; with Pediatric Plus 0.03 ... 4 L or off
Apnea monitoring 5 – 60 s or off Apnea monitoring 15 – 60 s or off
Tdisconnect 0 ... 60 s Tdisconnect 0 ... 60 s
Ti max 0 ... 60 s Ti max 0 ... 60 s

CORPORATE HEADQUARTERS REGION DACH REGION MIDDLE EAST, AFRICA REGION NORTH AMERICA
Drägerwerk AG & Co. KGaA Drägerwerk AG & Co. KGaA Drägerwerk AG & Co. KGaA Draeger, Inc.
Moislinger Allee 53–55 Moislinger Allee 53–55 Branch Office 3135 Quarry Road
23558 Lübeck, Germany 23558 Lübeck, Germany P.O. Box 505108 Telford, PA 18969-1042, USA
Tel +49 451 882 0 Dubai, United Arab Emirates Tel +1 800 4DRAGER
www.draeger.com Fax +49 451 882 2080 Tel +971 4 4294 600 (+1 800 437 2437)
[email protected] Fax +971 4 4294 699 Fax +1 215 723 5935
[email protected] [email protected]
REGION EUROPE
Manufacturer: Drägerwerk AG & Co. KGaA REGION ASIA PACIFIC REGION CENTRAL AND
Drägerwerk AG & Co. KGaA Moislinger Allee 53–55 Draeger Singapore Pte. Ltd. SOUTH AMERICA
Moislinger Allee 53–55 23558 Lübeck, Germany 25 International Business Park Dräger Panama S. de R.L.
23542 Lübeck, Germany Tel +49 451 882 0 #04-20/21 German Centre 59 East Street, Nuevo Paitilla,
Fax +49 451 882 2080 Singapore 609916 House 30, San Francisco Town
[email protected] Tel +65 6308 9400 Panama City, Panama
Fax +65 6308 9401 Tel +507 377 9100
asia.pacifi[email protected] Fax +507 377 9130
[email protected]

Locate your Regional Sales

Representative at:
www.draeger.com/contact