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Surgical Specialities-Vascular Surgery (38Qs)
Surgical Specialities-Vascular Surgery (38Qs)
This patient has peripheral arterial disease with typical deep punched out ulcers. The limb has signs
of chronic ischaemia with absent pulses. These ulcers usually occur in pressure areas such as the
ball of the foot or heel.
For each of the patients below, choose the most likely level of arterial disease from the list above.
Each option may be selected once, more than once or not at all.
Scenario 1
Rest pain and foot ulcers
A - Aorto-iliac occlusion« YOUR ANSWER
E - Aorto-iliac occlusion and superficial femoral artery occlusion« CORRECT ANSWER.
Scenario 2
Impotence
B - External iliac/common femoral occlusion« YOUR ANSWER
A - Aorto-iliac occlusion« CORRECT ANSWER.
Scenario 3
Calf claudication
C - Superficial femoral artery occlusion« CORRECT ANSWER.
Scenario 4
Thigh claudication
D - Crural vessel occlusion« YOUR ANSWER
B - External iliac/common femoral occlusion« CORRECT ANSWER.
Scenario 5
Buttock claudication
E - Aorto-iliac occlusion and superficial femoral artery occlusion« YOUR ANSWER
A - Aorto-iliac occlusion« CORRECT ANSWER.
Claudication pain usually occurs in the muscle group just distal to the diseased artery. Tissue loss
usually only results when there is disease at more than one level.
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
02. Theme: supra-aortic arterial surgey
A Carotid-carotid bypass
B Carotid-subclavian bypass
C Carotid endarterectomy
D Superficial temporal artery-middle cerebral artery bypass
E Thoracic-outlet decompression.
Page |
For each of the pathologies below, choose the procedure from the list above that may be required to
deal with the condition. Each option may be selected once, more than once or not at all. 1660
Scenario 1
Subclavian steal syndrome
A - Carotid-carotid bypass« YOUR ANSWER
B - Carotid-subclavian bypass« CORRECT ANSWER.
Scenario 2
Amaurosis fugax
B - Carotid-subclavian bypass« YOUR ANSWER
C - Carotid endarterectomy« CORRECT ANSWER.
Scenario 3
Unilateral 95% stenosis of the carotid bifurcation
C - Carotid endarterectomy« CORRECT ANSWER.
Scenario 4
Paget–Schroetter syndrome (axillary vein thrombosis)
D - Superficial temporal artery-middle cerebral artery bypass« YOUR ANSWER
E - Thoracic-outlet decompression« CORRECT ANSWER.
Scenario 5
Endovascular repair of a thoracic aneurysm where the landing zone involves the origin of the left carotid artery
(ie the origin of the left carotid artery is covered by the stent graft)
E - Thoracic-outlet decompression« YOUR ANSWER
A - Carotid-carotid bypass« CORRECT ANSWER.
Superficial temporal artery to middle cerebral artery bypass is now an obsolete procedure. Carotid
endarterectomy is indicated for both symptomatic and asymptomatic internal carotid artery stenosis
70%. Stenting of thoracic aneurysms is becoming preferable to ope n surgery due to its much lower
peri-/post-operative mortality. If the aneurysm is close to the origins of the left subclavian and left
carotid vessels, these may be covered by the stent as long as a carotid–carotid bypass is performed
before stenting, thereby preventing a left cerebrovascular accident. The left subclavian can usually be
covered without impunity. Paget–Schroetter syndrome (axillary vein thrombosis) is likely to recur
unless the thoracic outlet is decompressed.
04. A 72-year-old man is transferred to your vascular centre with a suspected AAA. Fast scan at the
initial hospital emergency department showed a 9cm suspected aneurysm. Vital signs are as follows;
heart rate 100, Blood pressure 117 systolic, 02sats 94% on room air. What is the next appropriate
step? Select one answer only.
This patient has a AAA and at present is relatively haemodynamically stable. Preferably when the Page |
surgical team is alerted to this transfer, radiology should be alerted to be on standby. Once the patient
is rapidly assessed in the emergency department and if haemodynamically stable and appears safe to 1661
do so as in the case above, an urgent CT scan should be performed. This allows confirmation of
diagnosis of the aneurysm and potential complication – leak or rupture and allows the vascular
surgeon to review the anatomy including the neck of the aneurysm as this aids planning for surgical
intervention including potential suitability for EVAR which if available can be performed in the
emergency setting if the patient is stable. Clearly if the patient is haemodynamically unstable and a
ruptured AAA is suspected, the vascular consultant should be informed and there should be no delay
to theatre.
For each of the case descriptions below, select the most appropriate diagnosis from the list above.
Each option may be used once, more than once, or not at all.
Scenario 1
A 54-year-old woman with known inflammatory bowel disease presents with a large nodulopustular ulcerating
lesion over her right anterior shin. It has a blue overhanging necrotic edge. Her ankle–brachial pressure
indices are normal.
A - Squamous cell carcinoma« YOUR ANSWER
C - Pyoderma gangrenosum« CORRECT ANSWER.
Pyoderma gangrenosum (PG) are recurring nodulopustular ulcers commonly affecting the legs,
abdomen and face. They are tender and have a red or blue overhanging necrotic edge. They heal with
cribriform scars. Over 50% of patients with PG have associated underlying active or quiescent
systemic disease – such as inflammatory bowel disease, seronegative rheumatoid arthritis, a
lymphoproliferative disease, autoimmune hepatitis or Wegener’s granulomatosis. The diagnosis of PG
is primarily clinical and by exclusion of other causes of cutaneous ulcerations with a similar
appearance; skin histology may help. Treatment is usually with immunosuppressants and
corticosteroids.
Scenario 2
A 57-year-old woman with varicose veins presents with a large ulcer over her left medial malleolus. This is
associated with surrounding lipodermatosclerosis and eczema. The ankle–brachial pressure index in this leg
is 1. The patient is moderately obese.
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
B - Hypertensive ulcer (Martorell syndrome) « YOUR ANSWER
H - Venous ulcer« CORRECT ANSWER.
Venous ulcers may develop spontaneously or following minor trauma. There may be a history of
varicose veins, deep venous thrombosis, chronic venous insufficiency, poor calf-muscle function or
arteriovenous fistulae. Other factors predisposing to venous ulceration include obesity, all risk factors
for deep-vein thrombosis, a family history of varicose veins and a history of leg fracture. In long-term Page |
venous insufficiency, the skin undergoes changes (atrophy and variable pigmentation), with the
dermis and subcutaneous tissue becoming indurated and fibrosed; this is termed 1662
lipodermatosclerosis. Venous eczema (erythema, scaling, weeping and itching) is a common feature
associated with such ulceration; this is distinct from cellulitis. The ankle–brachial pressure indices
are normal in patients with classic venous ulceration.
Scenario 3
A 59-year-old man presents with ulceration over the tips of his toes in his left foot and a large ulcer over his
right heel. He also complains of paraesthesias in both feet. The ankle–brachial pressure indices are 1.05 on
the right and 1.2 on the left. On neurological assessment, proprioception and vibration sense are reduced.
C - Pyoderma gangrenosum« YOUR ANSWER
D - Neuropathic ulcer« CORRECT ANSWER.
Neuropathic ulcers can result from peripheral sensory neuropathy secondary to diabetes mellitus. The
other causes of altered sensory neuropathy leading to neuropathic ulcers include spinal cord injuries,
spina bifida, tabes dorsalis, syringomyelia, alcohol abuse and leprosy. Neuropathic ulcers are
common at the sites of pressure or repeated trauma. The usual sites in the lower limb are the heads of
the metatarsals, the interdigital clefts, the heel (calcaneum) and the lateral malleolus. In diabetic
patients, the ankle–brachial pressure indices may be falsely elevated even in those with major vessel
disease. This is due to calcification of the vessel walls and medial sclerosis. Neurological assessment
may reveal altered sensation including proprioception and two-point discrimination in the foot or toes,
reduced vibration sense and absent ankle jerks.
Scenario 4
A 24-year-old woman of Jamaican origin presents with a 4-month history of painful ulceration over her right
shin. Ankle–brachial pressure indices are normal. The patient has mild splenomegaly. Her haemoglobin is 9.2
gm/dl.
D - Neuropathic ulcer« YOUR ANSWER
G - Sickle cell disease« CORRECT ANSWER.
Sickle cell disease is an hereditary haemolytic anaemia occurring mainly among those of Afro-
Caribbean origin. The haemoglobin S molecule crystallises during reduced blood oxygen tension,
causing vascular occlusion. Depending on the affected vessel, patients may have bone or joint pain,
priapism, neurological abnormalities or skin ulcers. The ulceration is due to occlusion of the
cutaneous microcirculation, leading to ischaemia and skin breakdown. In dark-skinned individuals,
there may be a non-specific increase in melanin pigmentation around the ulcer, which, if over the
ankle region, may be confused with the discoloration caused by haemosiderin around a venous ulcer.
Anaemia and splenomegaly are recognised features of sickle cell disease.
For each of the following profiles, select the most likely cause of the ulcer from the above list. Each
option may be used once, more than once, or not at all. Page |
Scenario 1 1663
A 54-year-old lady with known inflammatory bowel disease presents with a large nodulo-pustular ulcerating
lesion over her right anterior shin. It has a blue overhanging necrotic edge. The arterial blood pressure index
(ABPI) is normal.
A - Basal cell carcinoma « YOUR ANSWER
F - Pyoderma gangrenosum« CORRECT ANSWER.
Pyoderma gangrenosum is recurring nodulo-pustular ulceration that commonly affect the legs,
abdomen and face. The ulcers are tender with a red-blue overhanging necrotic edge and they heal
with cribriform scars. Pyoderma gangrenosum is associated with inflammatory bowel disease, acute
leukaemia, polycythaemia rubra vera, autoimmune hepatitis, Wegener’s granulomatosis and myeloma.
Scenario 2
A 57-year-old obese lady with varicose veins presents with a large ulcer over her left medial malleolus. This is
associated with surrounding lipodermatosclerosis and eczema. The ABPI in this leg is 1.05.
B - Erythema nodosum « YOUR ANSWER
J - Venous ulcer« CORRECT ANSWER.
Venous ulcers may develop spontaneously or following a minor injury. Risk factors include past
history of varicose veins and deep-venous thrombosis (DVT); all causes of varicose veins or DVT may
therefore predispose to venous ulceration. Venous incompetence leads to a high venous pressure
which causes pericapillary fibrin deposition, white cell activation and increased production of free
radicals. All these factors contribute to skin breakdown, causing ulceration. These ulcers usually lie
proximal to the medial or lateral malleolus, although they may extend to the ankle or dorsum of the
foot. Lipodermatosclerosis frequently accompanies long-standing venous incompetence. Increased
exudates leads to venous eczema, excoriation of the surrounding skin, itch and worsening of the
ulcer.
Scenario 3
A 59-year-old man presents with ulceration over the distal tips of three toes in his left foot and over his right
heel. He also complains of paraesthesia in both his feet. The ABPI is 1.02 on the right and 1.16 on the left. On
neurological assessment, proprioception and vibration sense are reduced.
C - Hypertensive ulcer (Martorell’s ulcer) « YOUR ANSWER
E - Neuropathic ulcer« CORRECT ANSWER.
Neuropathic ulcers can result from peripheral sensory neuropathy secondary to diabetes mellitus. The
other causes for altered sensory neuropathy, leading to neuropathic ulcers include: spinal cord
injuries, spina bifida, tabes dorsalis, syringomyelia, alcohol abuse and leprosy. Neuropathic ulcers are
common at the sites of pressure or repeated trauma. The usual sites in the lower limb are the head of
the metatarsals, interdigital clefts, heel (calcaneum) and the lateral malleolus. In diabetic patients, the
arterial blood pressure index (ABPI) may be falsely elevated, because of calcification of the vessel
walls and medial sclerosis, even in those with major vessel disease. Neurological assessment of the
foot and toes may reveal altered sensation including proprioception and two-point discrimination,
reduced vibration sense and absent ankle jerks.
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
Scenario 4
A 30-year-old Afro-Caribbean lady presents with a 4-month history of a painful ulcer over her right shin. She
mentions that she does not have a functioning spleen. ABPIs are normal.
D - Necrobiosis lipoidica « YOUR ANSWER
G - Sickle cell disease« CORRECT ANSWER.
Sickle cell disease is hereditary haemolytic anaemia occurring mainly among those of Afro-Caribbean Page |
origin, often involving functional asplenia from childhood. The haemoglobin ‘S’ molecule crystallises
during reduced blood oxygen tension causing vascular occlusion. Depending on the affected vessel, 1664
patients may have bone or joint pain, priapism, neurological abnormalities, skin ulcers. Ulceration is
due to occlusion of the cutaneous microcirculation, leading to ischaemia and skin breakdown. In dark-
skinned individuals, there may be a non-specific increase in melanin pigmentation around the ulcer
which, if over the ankle region, may be confused with haemosiderin discoloration around a venous
ulcer.
For each of the patients described below, select the treatment of choice from the list of options above.
Each option may be used once, more than once, or not at all.
Scenario 1
A woman has thrombosed varicose veins and cellulitis.
A - Compression bandaging« YOUR ANSWER
B - Elevation, rest, NSAIDs and antibiotics« CORRECT ANSWER.
The woman with thrombosed varicose veins and cellulitis should be treated with elevation, rest,
NSAIDs and antibiotics.
Scenario 2
A woman develops a swollen and tender left leg 5 days after surgery.
B - Elevation, rest, NSAIDs and antibiotics« YOUR ANSWER
D - Subcutaneous low molecular weight heparin« CORRECT ANSWER.
One should also suspect a deep-vein thrombosis in a patient with a swollen and tender leg post-
operatively. It is best to perform some imaging (duplex Doppler study) before commencing treatment
for this second scenario.
Scenario 3
A 64-year-old woman, who is a known case of venous insufficiency, presents with hypotension and profuse
bleeding from the medial malleolus of the right leg. Conservative treatment has failed.
C - Emergency surgery« CORRECT ANSWER.
C – Emergency surgery
A patient with venous insufficiency and profuse bleeding from an ulcer should have emergency
surgery to stop the bleeding.
For each of the patient scenarios below, select the aetiology of the most likely ulcer from the above
list. Each option may be used once, more than once, or not at all.
Page |
Scenario 1
A 72-year-old woman presents with a 2-year history of an intermittently healing, shallow ulcer above the right 1665
medial malleolus. The surrounding skin has a brown discoloration. Ten years previously, she was involved in
an RTA and sustained pelvic fractures, which were treated with traction and bedrest.
A - Arterial« YOUR ANSWER
D - Postphlebitic« CORRECT ANSWER.
Scenario 2
A 68-year-old insulin-dependent diabetic man presents with a progressively worsening deep, painless ulcer
beneath the heel of his right foot, which has gradually deteriorated in the past two months. The ankle appears
deformed, and the ulcer is surrounded by wet macerated skin and culture has grown MRSA and
Pseudomonas species. Strong pedal pulses are present on examination.
B - Diabetic« CORRECT ANSWER.
Scenario 3
A 94-year-old man presents with a deep, painful ulcer at the tip of his great toe. He has gradually been getting
less mobile over the last few months and the pain in his toe prevents him from sleeping.
C - Neoplastic« YOUR ANSWER
A - Arterial« CORRECT ANSWER.
Leg ulcers often have multiple aetiologies. The aetiology is usually apparent from taking a clear
history and identifying the site of the ulcer. The most common causes of leg ulcers are venous, mixed,
arterial, neuropathic, vasculitic (including rheumatoid arthritis) and neoplastic. Venous and
postphlebitic ulcers tend to be situated in the gaiter area and have sloping edges.Arterial ulcers have
punched-out edges and often occur at pressure areas at the extremities, eg toes.Diabetic ulcers often
occur at the site of trauma or pressure points. In the question above, the presence of strong pedal
pulses excludes an arterial aetiology for the ulcers, while the ulcer location and Charcot-type joint
suggest a neuropathic component (in this case, secondary to poorly controlled diabetes). Neoplastic
ulcers have raised, rolled or everted edges and may occur anywhere.
Scenario 1
A 57-year-old man presents with left-sided cramping calf pain after walking approximately 100 metres.
Examination of both lower limbs reveals no significant abnormalities. Page |
A - Above-knee amputation« YOUR ANSWER
C - Atherosclerosis risk factor reduction« CORRECT ANSWER. 1666
This patient has intermittent claudication, a symptom of chronic lower limb atherosclerosis. Initial
management involves: risk factor reduction, including cessation of smoking, lipid-lowering drugs,
anti-platelet medication, good diabetic control if appropriate; regular exercise as part of a supervised
exercise programme and weight loss. Surgical intervention is only indicated when the patient has
disabling claudication, critical limb ischaemia, ulcers, or gangrene. The two main options are:
percutaneous angioplasty (preferable) or bypass surgery.
Scenario 2
A 64-year-old man presents with sudden onset of severe left-sided calf pain. On examination his left foot is
pale and cold; on the affected side he has no palpable pulses below the femoral pulse. He is currently
recovering from a recent cerebrovascular accident.
B - Aortofemoral bypass« YOUR ANSWER
N - Surgical thromboembolectomy« CORRECT ANSWER.
This patient has a classic presentation of acute lower ischaemia, with four of the six Ps: pallor,
pulselessness, paraesthesia, paralysis, ‘perishing’ cold and pain. Percutaneous thrombolytic
thromboembolectomy is the treatment of choice unless contraindicated, as in this scenario, in which
case the patient should procede to surgical thromboembolectomy. Contraindications to thrombolysis
include: cerebrovascular accident within the past 2 months, recent surgery, or previous thrombolytic
therapy.
Scenario 3
A 37-year-old woman presents with prominent unsightly leg veins, which cause discomfort on prolonged
standing. Examination reveals tortuous dilated subcutaneous veins along the lateral aspect of the right calf;
tourniquet tests indicate that when tied around the upper thigh and again just above the knee, the varicosities
refill upon standing; however, when tied just below the knee they are controlled. She is currently taking oral
contraception.
C - Atherosclerosis risk factor reduction« YOUR ANSWER
M - Short saphenous vein surgery« CORRECT ANSWER.
This patient has a classic presentation of symptomatic varicose veins. Injection sclerotherapy is not
applicable, first as it is contraindicated in those taking oral contraceptives, and second as it only
provides short-term benefit in those with major incompetence of either long or short saphenous veins.
The tourniquet test clearly indicates short saphenous incompetence, hence the need for short
saphenous ligation and stripping. General consensus would suggest that duplex scanning should be
performed to confirm the diagnosis and to site the junction for surgery (this is not necessary for long-
saphenous disease unless the veins are recurrent).
What initial investigation would you perform for each of the patients listed below? Each option may be
used once, more than once, or not at all.
Scenario 1
A 71-year-old man presents with a normal pulse, left carotid bruit and left TIAs.
A - Carotid angiogram« YOUR ANSWER Page |
B - Carotid Doppler« CORRECT ANSWER.
1667
Thirty per cent of carotid bruits heard on auscultation are not because of carotid stenosis. The initial
investigation that should be performed here is a Doppler ultrasound scan. This may be followed by
digital subtraction angiography or magnetic resonance angiography (MRA), but many centres will rely
on colour duplex Doppler alone if performed by an experienced operator.
Scenario 2
A 71-year-old man presents with a normal pulse, left carotid bruit and a dense left hemiplegia.
B - Carotid Doppler« YOUR ANSWER
C - CT scan« CORRECT ANSWER.
In cases where a persistent neurological deficit has occurred a CT scan must be carried out initially to
exclude a space-occupying lesion.
The following scenarios describe patients with leg ulceration. From the above list of causes of
ulceration, choose the most appropriate answer. Each item may be used once, more than once, or not
at all.
Scenario 1
A 55-year-old diabetic man presents with a large painless ulcer on the sole of his foot. On examination, the
ulcer appears deep with healthy surrounding skin. The foot feels warm and his ankle-brachial pressure index
is 0.8.
A - Arteriovenous fistula« YOUR ANSWER
E - Neuropathic ulcer« CORRECT ANSWER.
These ulcers occur in denervated tissue and result from local ischaemia, usually caused by non-
perceived local trauma. They are characteristically painless and have a good blood supply (although
diabetic neuropathy being a common cause may also lead to large-vessel atherosclerosis, resulting in
a mixed picture of arterial and neuropathic ulceration). The causes of neuropathic ulceration may be
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
divided into peripheral nerve lesions and spinal cord lesions. The former consist of diabetes, nerve
injuries and leprosy, while spina bifida, tabes dorsalis and syringomyelia comprise the second group.
Scenario 2
A 27-year-old man presents with abdominal pain, bloody diarrhoea and weight loss. On examination he is
noted to have some areas of necrotising ulceration surrounded by erythema over his legs, which are acutely
painful.
B - Ischaemic ulcer« YOUR ANSWER Page |
F - Pyoderma gangrenosum« CORRECT ANSWER.
1668
This man may have undiagnosed ulcerative colitis. The lesions at first resemble boils, which
subsequently break down to form necrotic ulcers with purple edges. Pyoderma gangrenosum is also
associated with rheumatoid arthritis, multiple myeloma and leukaemia.
Scenario 3
A 60-year-old lady presents with brown discoloration of both calves and a large left medial malleolar ulcer that
has developed over many years. A central raised patch of friable, irregular, nodular growth is noted.
C - Necrobiosis lipoidica« YOUR ANSWER
D - Neoplastic ulcer« CORRECT ANSWER.
This woman has a Marjolin’s ulcer or a squamous cell carcinoma arising from chronic inflammation in
a long-standing benign ulcer or scar. This commonly occurs in a venous ulcer making constant
review of such patients important.
For each of the patients described below, select the procedure of choice from the list of options
above. Each option may be used once, more than once, or not at all.
Scenario 1
A 50-year-old man has a 50-yard (~45 m) claudication distance, with complete occlusion of the lower aorta,
with patent femoral vessels.
A - Aortobifemoral bypass« CORRECT ANSWER.
Scenario 2
A 79-year-old man with emphysema requires home oxygen. He has complete occlusion of the aorta, with
patent femoral vessels. His toes appear gangrenous and dusky.
B - Axillobifemoral bypass« CORRECT ANSWER.
Scenario 3
A 43-year-old postman, otherwise fit and well, who is a non-smoker presents with acute onset claudication in
both feet – he is determined to go back to work. He has an aortic bifurcation block with good femoral run-off
on both sides.
C - Femoral-to-femoral crossover« YOUR ANSWER
A - Aortobifemoral bypass« CORRECT ANSWER.
An aortobifemoral bypass graft has the highest patency rate of any bypass procedures to the femoral
vessels. An axillobifemoral bypass graft should only be considered in the very high-risk surgical
patient who has critical ischaemia. It should not be performed in patients with claudication.
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
13. A 76-year-old woman attends for review of an ulcer that appeared 2 weeks ago over the medial
aspect of her lower left leg. This is shallow with sloping edges. On examination there is
hyperpigmentation of surrounding skin. She takes warfarin for a previous recurrent DVT. What is the
likely diagnosis? Select one answer only.
This patient has a venous ulcer as a consequence of poor venous flow after previous DVT. The
hyperpigmentation is lipodermatosclerosis from haemosiderin deposition. Typically venous ulceration
affects the ‘gaiter’ area in the lower medial third of the lower limb. The ulcers have gently sloping
edges, are shallow and flat with granulation tissue with healing or slough on the base.
14. Theme: Management of arterial disease
A Percutaneous angioplasty
B Femoropopliteal bypass graft
C Emergency aortoiliac bypass graft
D Endovascular stent graft
E Below-knee amputation.
For each of the clinical scenarios below select the most appropriate action. Each option may be used
once, mor than once, or not at all.
Scenario 1
A 56-year-old man with a necrotic arterial ulcer on his shin has an angiogram. This reveals a solitary, short
segment, distal superficial femoral artery (SFA) occlusion with single-vessel run-off on that side.
A - Percutaneous angioplasty« CORRECT ANSWER.
Short segment superficial femoral artery (SFA) occlusions are usually very amenable to angioplasty,
and restoration of distal circulation is likely to allow the necrotic ulcer to heal with close supervision.
Scenario 2
A 60-year-old man is found to have a right iliac aneurysm at angiography. However, during the procedure the
aneurysm is ruptured by the guidewire. The patient becomes hypotensive
B - Femoropopliteal bypass graft« YOUR ANSWER
D - Endovascular stent graft « CORRECT ANSWER.
There is already a catheter sheath in place, and a straight covered stent graft is kept close to hand in
such procedures for exactly this reason.
Scenario 3
Angiography of a 56-year-old male shows disease involving a long segment of the SFA on the same side as a
foot with a gangrenous-looking toe.
C - Emergency aortoiliac bypass graft« YOUR ANSWER
B - Femoropopliteal bypass graft« CORRECT ANSWER.
Traditionally a femoropopliteal bypass would be considered but long-segment occlusions of SFA with
good distal run-off, and also popliteal artery are being treated with endovascular stenting. The foot is
likely to still be viable and non-resolving digital gangrene may require only local amputation.
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
Scenario 4
A 35-year-old male involved in a road traffic accident has a grossly comminuted compound fracture of his right
tibia with no distal pulses felt. His lower leg and foot are very cold to feel and white. He is otherwise stable but
in a lot of pain.
D - Endovascular stent graft « YOUR ANSWER
E - Below-knee amputation« CORRECT ANSWER
Page |
This difficult case shows a non-salvageable lower limb which if left will only become necrotic,
gangrenous and cause much more life-threatening problems. It is literally life or limb and, by deciding 1670
early, the level of amputation can be restricted to below knee.
For each of the patients below, choose the most appropriate management from the list above. Each
option may be selected once, more than once or not at all.
Scenario 1
A 60-year-old patient; no significant past medical history; bilateral rest pain; complete occlusion of both
common iliac and external iliac arteries
A - Best medical treatment and exercise« YOUR ANSWER
C - Aorto-bifemoral graft« CORRECT ANSWER
Scenario 2
An 82-year-old patient; bed-bound secondary to right-sided cerebro-vascular accident; extensive gangrene of
right foot; complete occlusion of both common and external iliac arteries
B - Angioplasty and stenting« YOUR ANSWER
E - Amputation« CORRECT ANSWER
Scenario 3
A 79-year-old patient; history of coronary heart disease and impaired renal function; bilateral gangrenous toes;
complete occlusion of both common iliac and external iliac arteries
C - Aorto-bifemoral graft« YOUR ANSWER
D - Axillo-bifemoral graft« CORRECT ANSWER
Scenario 4
A 70-year-old patient; sedentary life style; claudicates at 400 yards; short occlusions of both common iliac
arteries
D - Axillo-bifemoral graft« YOUR ANSWER
A - Best medical treatment and exercise« CORRECT ANSWER
Scenario 5
A 79-year-old patient; enthusiastic golfer; claudicates at 100 yards; short occlusions of both common iliac
arteries
E - Amputation« YOUR ANSWER
B - Angioplasty and stenting« CORRECT ANSWER
Patients with claudication do not require radiological/surgical intervention unless it interferes with their life style
and they are willing to accept the small but significant risks associated with the procedures involved. Iliac
angioplasty/stenting does achieve very good results with low complication rates in those patients with short
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
occlusions. Patients with critical limb ischaemia require revascularisation to prevent them from losing their leg
in the near future. What they are offered depends on the length of the occlusion (surgery vs angioplasty) and
on their level of fitness (aortic vs extra-anatomical bypass). Patients who are unlikely to walk in the future may
be better managed with a primary amputation.
16. The medical team ask you to review a patient on the ward who has developed a swollen painful
pale oedematous leg. Looking through the notes you see the patient was diagnosed with a deep vein Page |
thrombosis last week. Pulses are present. Which is the likely diagnosis? Select one answer only.
1671
Atherosclerotic Ischaemia« YOUR ANSWER
Deep Vein Thrombosis
LymphodemaTarda
Phlegmasia Alba Dolens« CORRECT ANSWER
Phelgmasia Cerulea Dolens.
This condition is related to extensive complicated deep vein thrombosis. The deep venous system is
totally occluded and must rely on the superficial venous system. However, this superficial system is
now under pressure of high flow from the arterial system which leads to a painful oedematous white
leg (‘alba’ meaning white). If this progresses all venous outflow is occluded leading to cerulean dolens
– here the arterial supply is impeded and ischaemia and gangrene occur. Thrombolysis is an effective
treatment but needs to be undertaken with caution.
What initial investigation would you perform for each of the clinical scenarios below? Each option
may be used once, more than once, or not at all.
Scenario 1
A 71-year-old man with left carotid bruit and normal pulse and left transient ischaemic attacks (TIAs).
A - Computed tomography (CT)« YOUR ANSWER
B - Carotid Doppler ultrasonography« CORRECT ANSWER
Scenario 2
A 71-year-old man with left carotid bruit and normal pulse plus a dense left hemiplegia.
B - Carotid Doppler ultrasonography« YOUR ANSWER
A - Computed tomography (CT)« CORRECT ANSWER
Thirty per cent of carotid bruits heard on auscultation are not due to carotid stenosis. The initial
investigation that should be performed is a Doppler ultrasound scan in patient 1. In cases where a
persistent neurological deficit has occurred a CT scan must be carried out initially to exclude a space-
occupying lesion.
The following patients all present with swelling affecting the lower limb. From the list above, select the
most likely diagnosis. The items may be used once, more than once, or not at all.
Scenario 1
A 21-year-old woman is referred to clinic with a history of intermittent oedema of the face and extremities. Her
mother also suffers with similar symptoms.
A - Angio-oedema« CORRECT ANSWER
Hereditary angio-oedema is inherited as an autosomal dominant condition. It arises as a result of a
deficiency in the complement system regulation, and is characterised by recurrent attacks of swelling
of the face and extremities that subsequently resolve. The oedema is often associated with erythema.
Scenario 2
A 14-year-old boy is referred to clinic for assessment of varicose veins and associated swelling of his left leg.
As he enters the consultation room you note that he has a ‘short-leg’ gait. His varicose veins are large and do
not lie in a typical distribution.
B - Congestive cardiac failure« YOUR ANSWER
H - Klippel–Trenaunay syndrome« CORRECT ANSWER
This syndrome is characterised by dilated veins, associated with bony and soft tissue deformity,
elongation of the limb, capillary naevi and limb oedema. There are no arterial abnormalities. The
diagnosis is suggested as varicose veins are present since birth or early childhood, and are often
present on the outside of the leg, not the inner side where most varicose veins appear.
Scenario 3
A 48-year-old woman presents with a history of unilateral swelling of the right leg. There is no history of
venous obstruction. Her general practitioner has sent copies of recent full blood counts, urea & electrolytes,
and liver function tests, all of which are normal. Isotope lymphography demonstrates delayed transit of
radionuclide on the right side.
E - Chronic venous insufficiency« YOUR ANSWER
M - Primary lymphoedema« CORRECT ANSWER
It has been suggested that these groups represent different parts of the same spectrum of disease,
which has been attributed to aplasia, hypoplasia, or hyperplasia of the lymph vessels. Once other
causes of oedema have been excluded, the diagnosis of primary lymphoedema may be confirmed
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
using isotope lymphography, computed tomography scanning, magnetic resonance imaging, or
contrast lymphangiography. The aims of treatment are to reduce limb swelling and weight, reduce the
risk of infection, and improve function. This may be achieved using conservative measures
(elevation/compression of affected limb). Surgical intervention involves debulking (of excess skin and
subcutaneous tissue) or bypass procedures (where regional blockade of lymphatics is evident).
Lymphoedema is an accumulation of tissue fluid secondary to a fault in the lymphatic system Page |
(abnormalities of lymph formation or lymph clearance). This may be primary, in the absence of other
1673
causes, or secondary to malignant disease, surgery (eg post-radical mastectomy/groin dissection),
radiotherapy or infection (filariasis, pyogenic tuberculosis). The differential diagnosis of
lymphoedema includes other causes of tissue oedema, which may be broadly classified as:
1. systemic disorders, eg cardiac/renal/liver failure, hereditary angiooedema, etc
2. venous disorders, eg post-thrombotic syndrome, extrinsic compression
(pregnancy/tumour/retroperitoneal fibrosis), Klippel–Trenaunay syndrome
3. miscellaneous disorders, eg arteriovenous malformations, factitious oedema etc.
For each of the patients described below, select the most likely treatment from the list of options
above. Each option may be used once, more than once or not at all. You may believe that more than
one treatment is possible but you should choose the ONE most likely treatment.
Scenario 1
A 54-year-old woman with thrombosed varicose veins and cellulitis.
A - Elevation, non-steroidal anti-inflammatory drugs (NSAIDs) and antibiotics« CORRECT ANSWER
Scenario 2
A 49-year-old lady, 5 days post-left hip replacement, with a swollen, red and tender left leg.
B - Urgent surgery« YOUR ANSWER
C - Low molecular weight heparin« CORRECT ANSWER
In patients with a high clinical suspicion of DVT, therapeutic low molecular weight heparin should be
commenced, and urgent imaging (e.g. venous duplex imaging) should be organised.
Scenario 3
A 70-year-old man with long history of venous ulcer over the medial malleolus.
C - ILow molecular weight heparin« YOUR ANSWER
D - Compression bandaging« CORRECT ANSWER
A 70-year-old man with a poorly healing venous ulcer should be treated with appropriate compression
bandaging.
Scenario 4
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
A 64-year-old woman, with known history of venous insufficiency, presents with hypotension and profuse
bleeding from the medial malleolus of her right leg.
D - Compression bandaging« YOUR ANSWER
B - Urgent surgery« CORRECT ANSWER
A patient with venous insufficiency with profuse bleeding from an engorged vein (long saphenous
vein in this case) should have urgent surgery to stop the bleeding. Page |
20. Theme: Lower limb ischaemia 1674
A Angioplasty
B Aortofemoral bypass graft
C Correct the risk factors and provide conservative treatment
D Femoropopliteal bypass graft
E Surgical embolectomy.
Select the most appropriate option above for the treatment of the patients below. Each option may be
used once, more than once, or not at all.
Scenario 1
A 55-year-old man presents with a sudden onset of severe pain in his left foot and calf. There is no preceding
history of intermittent claudication but he experienced a myocardial infarction two weeks ago. He is unable to
move his foot, which is now mottled and cold. There are absent pulses below his left knee but a palpable
femoral pulse. ECG reveals Q waves with sinus rhythm.
A - Angioplasty« YOUR ANSWER
E - Surgical embolectomy« CORRECT ANSWER.
The first patient is likely to have had a mural thrombus post MI that has embolised to his leg. He may
also have been in atrial fibrillation previously. As he has acute limb ischaemia, surgical embolectomy
is indicated.
Scenario 2
A 75-year-old man presents to the outpatient clinic with right buttock and thigh pain when walking 100 yards.
He smokes 30 cigarettes per day and has a poor cardiac history (three previous MIs, hypertension and left
ventricular failure). Ankle brachial Doppler pressure ratio in the right leg is 0.3 and that on the left 0.6. An
arteriogram shows an isolated 3 cm 80% stenosis in the right common iliac artery with good run-off. There is
evidence of 40% stenosis in the left superficial femoral artery with well-developed collaterals. His symptoms
have persisted despite best medical care.
B - Aortofemoral bypass graft« YOUR ANSWER
A - Angioplasty« CORRECT ANSWER.
Angioplasty is useful for short stenoses. This has better results for proximal stenosis above the
inguinal ligament. For occluded vessels the procedure is now possible in specialist centres using
cutting-balloon or subintimal angioplasty techniques.
Scenario 3
A 65-year-old man presents with pain in his foot when at rest. He has given up smoking and is otherwise fit
and well. Angiography shows a 10-cm block in the superficial femoral artery with good distal run-off.
C - Correct the risk factors and provide conservative treatment« YOUR ANSWER
D - Femoropopliteal bypass graft« CORRECT ANSWER
A patient with rest pain has critical ischaemia and needs urgent intervention. A 10-cm stenosis is too
long for a successful angioplasty. A good distal run-off would allow distal bypass grafting. The SFA is
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
the commonest site for lower limb atherosclerosis because the vessel narrows as it passes through
the adductor hiatus.
For each of the patients described below, select the most likely intervention from the list of options
above. Each option may be used once, more than once, or not at all.
Scenario 1
A patient has resolving right-sided hemiplegia following a CVA. A carotid duplex shows 99% stenosis of the
left internal carotid artery and a completely occluded right internal carotid artery.
A - Carotid angiography« YOUR ANSWER
F - Left carotid endarterectomy« CORRECT ANSWER
Scenario 2
A 30-year-old patient with optic neuritis develops foot drop.
B - Carotid duplex« YOUR ANSWER
D - MRI head« CORRECT ANSWER
Scenario 3
A resolving recent left-sided hemiparesis with 90% right internal carotid artery stenosis.
C - CT head« YOUR ANSWER
E - Right carotid endarterectomy« CORRECT ANSWER
Patients with carotid territory TIAs, amaurosis fugax or a stroke (with subsequent recovery), and a >
70% stenosis should be offered endarterectomy. The risks of the operation are less than the risk of
suffering a disabling stroke, providing the operation is performed within 6 months of the stroke.
Endarterectomy should carry a mortality of < 2%, and a 1-2% risk of stroke. It is normally too late to
operate on completely occluded arteries. Patients with lesser degrees of stenosis should be given
antiplatelet drug therapy. A young patient with optic neuritis and foot drop should first have an MRI
scan of the brain to look for demyelinating disease.
22. A 15-year-old girl attends the vascular clinic with recent right leg swelling. On examination she has
confluent swelling to the thigh with pitting oedema. Examination of the groin and abdomen is
unremarkable, as is ultrasound of the abdomen and groin. Lymphatic abnormality was seen on
lymphoscintigraphy. Which is the likely diagnosis? Select one answer only.
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
This is primary lymphoedema that occurs after puberty and before the age of 35 years. It is more
common in females than males. It is the recent diagnosis in the 15 year old female which makes this
diagnosis most likely in this female along with any obvious aetiology. Kippel-Trenaunay Syndrome
causes limb hypertrophy - characterised with a capillary haemangioma, venous malformations and
varicosities that can be superficial or deep involving muscle, bone and viscera and limb abnormalities
with limb lengthening.Lymphoedema Praecox, Tarda and Milroy Disease are all example of primary Page |
lymphoedema. Milroy is congentiallymphoedema. Praecox occurs before the age of 35 and usually
around puberty. Tarda is primary lymphoedema occurring after the age of 35. Secondary 1676
lymphoedema occurs as a consequence of another aetiology or surgery.
23. You are called to see an 8-year-old girl admitted overnight following an emergency open reduction
and internal fixation of her right supracondylar fracture. She is complaining of severe pain and
tingling in her right hand. On examination there is pain on passive flexion of the hand. Which is the
likely diagnosis? Select one answer only.
This occurs when tissue pressure in a closed muscle compartment is greater than the perfusion
pressure and leads to muscle and nerve ischemia. This can readily occur after supracondylar
fractures. Passive flexion of the muscle induces pain is a reliable sign. Pressure in the compartment
must be released. In this case you must immediately split the hard plaster of paris cast to reduce the
pressure on the limb. However, if this does not help the symptoms, the patient would require an
urgentfasciotomy to release the muscle compartment pressure. Serious consequences arise if
compartment syndrome is missed with necrosis of the nerve and muscles resulting in ischaemic
contractures – in the upper limb this is classically Volkmann’s Ischemic Contracture.
24. A 64-year-old smoker attends for review due to intermittent pain in the back of the right calf on
walking. After 30 yards she needs to stop and rest to ease the pain. Which is her likely ABPI value?
Select one answer only.
This patient has intermittent claudication. Ankle Brachial Pressure Index (ABPI) aids assessment of
peripheral arterial disease and aids the assessment of severity in the legs.
ANKLE BP systolic / Brachial BP Systolic = ABPI >1 common in diabetic patients due to calcified
arteries obscuring the true result so is unreliable.
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
1. 1 Normal
2. 0.95 -0.5 Intermittent Claudication
3. 0.5 -0.3 Rest Pain
4. <0.2 Gangrene.
For each of the patients below, choose the most likely ABPI value from the list above. Each option
may be selected once, more than once or not at all.
Scenario 1
Walks unlimited distances
A - 1.1« CORRECT ANSWER.
Scenario 2
Poorly controlled diabetic with Charcot ankle arthropathy
B - 0.7« YOUR ANSWER
E - Incompressible« CORRECT ANSWER.
Scenario 3
Claudicates at 200 yards
C - 0.4« YOUR ANSWER
B - 0.7« CORRECT ANSWER.
Scenario 4
Rest pain both day and night, as well as gangrene of the first and second toes
D - 0.1« CORRECT ANSWER.
Scenario 5
Rest pain at night but no ulcers or gangrene
E - Incompressible« YOUR ANSWER
C - 0.4« CORRECT ANSWER.
Clinical presentation: ankle brachial index· normal > 0.90· claudication 0.50–0.90· rest pain 0.21–0.49·
tissue loss < 0.20
> 1.25, commonly seen in diabetics.
26. A 79-year-old woman presents with an ulcer over the medial aspect of her lower right leg. Although
she has had this for months, recently it has become increasingly painful. The edges of the ulcer have
become raised and thickened. What is the most likely diagnosis? Select one answer only.
Marjolin’s Ulcer« YOUR ANSWER
Post-Phlebitic Ulcer
Traumatic Ulcer
Vascular Ulcer
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
Vasculitic Ulcer.
This is a Marjolin’s Ulcer, in which a chronic venous ulcer has undergone malignant change. This is a
type of squamous cell carcinoma and is diagnosed by the description of change in a longstanding
ulcer that is tender with thickened edges. Diagnosis is by biopsy.
Page |
27. Theme: 5-year graft patency rates
A Aortobifemoral graft 1678
B Axillofemoral graft
C Femoral–femoral crossover graft
D Femoropopliteal PTFE graft patency (below knee)
E Reversed vein femoropopliteal graft.
For each of the percentages below, select the most likely single graft from the options listed above.
Each option may be used once, more than once, or not at all.
Scenario 1
70%
A - Aortobifemoral graft« YOUR ANSWER
E - Reversed vein femoropopliteal graft« CORRECT ANSWER.
Scenario 2
80%
B - Axillofemoral graft« YOUR ANSWER
C - Femoral–femoral crossover graft« CORRECT ANSWER.
Scenario 3
60%
C - Femoral–femoral crossover graft« YOUR ANSWER
B - Axillofemoral graft« CORRECT ANSWER.
Scenario 4
35%
D - Femoropopliteal PTFE graft patency (below knee)« CORRECT ANSWER.
Scenario 5
90%
E - Reversed vein femoropopliteal graft« YOUR ANSWER
A - Aortobifemoral graft« CORRECT ANSWER.
Patency rates are related to the force and volume of the inflow and the runoff away from the graft. If
the run-off is poor then blood that passes into the graft will be functionless; therefore, flow will be
greatly reduced so leading to graft occlusion and failure. Synthetic grafts used below the inguinal
ligament are vastly inferior to vein grafts.
28. The medical team ask for a vascular opinion on a 62 year old woman who has lower limb
ulceration and a persistent cough. On examination, multiple ulcerations that are irregular, friable with
an undermined edge and a bluish tinge are seen on both lower limbs. Pulses are present. CXR shows
a cavitational lesion in the right upper lobe. What is the likely aetiology of these ulcers? Select one
answer only.
Arterial « YOUR ANSWER
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
Infective« CORRECT ANSWER
Post-Phlebitic
Vasculitis
Venous.
Page |
This patient has Tuberculosis. Usually respiratory or bone disease is concurrent. The description of
the ulcers are typical for tuberculous ulceration. 1679
29. Theme: medications used in those patients with peripheral vascular disease.
A Cilostazol
B Aspirin
C Clopidogrel
D Simvastatin
E Losartan.
For each of the statements below, choose the most appropriate drug from the list above. Each option
may be selected once, more than once or not at all.
Scenario 1
Angiotensin–II receptor antagonist
A - Cilostazol« YOUR ANSWER
E - Losartan« CORRECT ANSWER.
Scenario 2
Stabilises atheromatous plaque
B - Aspirin« YOUR ANSWER
D - Simvastatin« CORRECT ANSWER.
Scenario 3
Reduces serum levels of LDL cholesterol
C - Clopidogrel« YOUR ANSWER
D - Simvastatin« CORRECT ANSWER.
Scenario 4
Cyclo-oxygenase inhibitor
D - Simvastatin« YOUR ANSWER
B - Aspirin« CORRECT ANSWER.
Scenario 5
Phosphodiesterase inhibitor
E - Losartan« YOUR ANSWER
A - Cilostazol« CORRECT ANSWER.
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
function, relaxing vascular smooth muscle and increasing lipoprotein lipase activity. It is
contraindicated in those patients with ischaemic heart disease.
Select the most appropriate option above for the treatment of the patients below. Each option may be
used once, more than once or not at all.
Scenario 1
A 55-year-old man presenting with a sudden onset of severe pain in his left foot and calf. There is no
preceding history of intermittent claudication. He is unable to move his foot which is now mottled and cold.
There are absent pulses below his left knee but a palpable femoral pulsation. Electrocardiogram (ECG)
reveals Q waves with sinus rhythm.
In the absence of precipitating factors this gentleman has probably dislodged a proximal embolus
which is now blocking the popliteal artery. He may have had a paroxysm of AF which has now
resolved. The treatment of choice is a surgical embolectomy and anticoagulation.
Scenario 2
A 75-year-old man presents to the outpatient clinic with right buttock and thigh pain after walking 100 yards.
He is a smoker of 30 cigarettes per day with poor cardiac history (3 previous MIs, hypertension and left
ventricular failure). Ankle brachial Doppler pressure ratio in the right leg is 0.3 and that on the left 0.6.
Arteriogram shows an isolated 3 cm 80% stenosis in the right common iliac artery with good run-off. There is
evidence of 40% stenosis in the left superficial femoral artery with well-developed collaterals. His Symptoms
have persited despite lifestyle modification.
As this gentleman has good distal run, off, a short segment stenosis, multilevel disease and
intermittent claudication, angioplasty is the treatment of choice in the first instance. If this doesn’t
work he may have to proceed to bypass grafting. In either event he should be counselled strongly to
stop smoking and start an appropriate anti-platelet agent.
Scenario 3
A 65-year-old man has been admitted to the emergency department; when you see him he presents with pain
in his foot while at rest. Investigation reveals 10 cm (superficial femoral artery (SFA) block. The patient has
given up smoking and on examination has a good constitution and is otherwise fit and well.
This gentleman has critical ischaemia with a long segment stenosis. A fem-pop bypass would be in
his best interests.
31. Theme: Varicose veins
A Compression and warfarin
B Elevation and NSAIDs
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
C LMW heparin
D Varicose vein surgery.
For each of the patients described below, select the most likely intervention from the list of above
options. Each option may be used once, more than once, or not at all.
Scenario 1 Page |
A 54-year-old man presents with varicose veins and a bleeding varicose ulcer.
A - Compression and warfarin« YOUR ANSWER 1681
D - Varicose vein surgery« CORRECT ANSWER.
Varicose veins must be dealt with surgically if they are suspected of causing an ulcerating lesion that
is bleeding intermittently – this should be done promptly.
Scenario 2
A 30-year-old woman presents with varicose veins and an acute episode of thrombophlebitis.
B - Elevation and NSAIDs« CORRECT ANSWER.
Episodes of thrombophlebitis are best treated by elevation, analgesics (NSAIDs are useful) and
external elastic support.
Scenario 3
A 45-year-old woman presents with varicose veins and a swollen leg. Duplex confirms a DVT.
C - LMW heparin« CORRECT ANSWER.
On confirmation of a DVT, patients should be started on LMW heparin as soon as possible assuming
there are no contraindications. This is continued until warfarin therapy can be instigated and made
theraputic. Warfarin therapy aims to prevent the formation of clots; heparin aims to prevent their
propagation and dispersal.
From each of the statements below, select the most appropriate investigation from the above list.
Each option may be used once, more than once, or not at all.
Scenario 1
What should be the initial investigation in a 65-year-old man presenting with an episode of amaurosis fugax
affecting his right eye?
B - CT scan of head« YOUR ANSWER
C - Duplex Doppler ultrasound of carotid arteries« CORRECT ANSWER.
Duplex Doppler ultrasound of the carotid arteries is the initial investigation of choice for carotid
stenosis. It is the quickest and safest investigation for amaurosis fugax. Subsequently, carotid
angiography (digital subtraction angiography) or MRA may be used to confirm the duplex findings.
Scenario 2
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
Which is the most appropriate investigation for a 28-year-old woman who collapses with a possible dense,
right-sided stroke?
A - Carotid angiography« YOUR ANSWER
B - CT scan of head« CORRECT ANSWER.
The 28-year-old with the dense stroke is most likely to have had an intracranial bleed necessitating a
CT of the brain. Page |
Scenario 3 1682
Which is the most appropriate procedure for intraoperative monitoring during carotid endarterectomy?
C - Duplex Doppler ultrasound of carotid arteries« YOUR ANSWER
F - Transcranial Doppler ultrasound« CORRECT ANSWER.
Transcranial Doppler measures the flow in the middle cerebral artery and is thus useful in the
intraoperative monitoring and investigation of postendarterectomy neurological episodes. Duplex
Doppler would also demonstrate patency of the carotid artery following endarterectomy. Nearinfrared
spectroscopy measures intracerebral blood flow but is not currently used for intraoperative
monitoring.
For each of the presentations below, select the most likely single treatment from the options listed
above. Each option may be used once, more than once or not at all.
Scenario 1
A 73-year-old diabetic woman presents with critical ischaemia of the right lower leg. Angiography reveals
extensive disease of the superficial femoral, popliteal and tibial arteries. Pulse-generated run-off assessment
indicates a good run-off in the posterior tibial artery.
A - Femoropopliteal bypass« YOUR ANSWER
C - Femorodistal bypass« CORRECT ANSWER.
Femorodistal bypass using an autogenous vein graft is the treatment of choice in this patient. The
absence of images of the posterior tibial, anterior tibial and common peroneal arteries on angiography
films must not be accepted as evidence of their occlusion.
Scenario 2
A 72-year-old man presents with a 4-h history of acute ischaemia of the left leg. Clinical examinations
demonstrate signs of acute ischaemia with no evidence of gangrene. There is no neurological deficit. An
urgent angiogram reveals a complete occlusion of the distal superficial femoral artery probably due to
thrombosis.
B - Percutaneous balloon angioplasty« YOUR ANSWER
E - Tissue plasminogen activator infusion (intra-arterial)« CORRECT ANSWER.
Intra-arterial thrombolysis with tissue plasminogen activator (TPA) or streptokinase is the treatment of
choice in this patient in view of the short history (4 h), absence of neurological deficit and
angiographic findings.
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
Scenario 3
A 57-year-old smoker presents with intermittent claudication of the right calf. The claudication distance is 70
m. Angiography reveals a 12 cm stenosis in the proximal superficial femoral artery with adequate distal run-off
present.
C - Femorodistal bypass« YOUR ANSWER
G - No treatment but recommend lifestyle changes« CORRECT ANSWER
Page |
BMT and lifestyle. This is single level disease and femoro-distal is not indicated. Femoro-popliteal or
angioplasty are options but are unlikely to be popular at this stage. 1683
Scenario 4
A 21-year-old motorcyclist presents with multiple injuries following a road traffic accident. Clinical examination
reveals a critically ischaemic right lower leg. The right dorsalis pedis pulse is feeble. The right calf is tense and
swollen. The intracompartmental pressure is 55 mmHg. Angiography shows no discontinuity of the arterial
tree.
D - Below knee amputation« YOUR ANSWER
F - Fasciotomy« CORRECT ANSWER
This patient has the compartment syndrome. Urgent fasciotomy is indicated in order to save his right
leg.
34. A worried mother brings her child to see you. He has just started walking and she has noticed that
he has a gait abnormality as his right leg appears longer than the other. He has prominent varicosities
on his right leg and a bluish ‘port-wine stain’ on his face. What is the likely diagnosis? Select one
answer only.
For each of the scenarios below, choose the most appropriate treatment option from the list above.
Each option may be selected once, more than once or not at all.
Scenario 1
An 85-year-old patient has no symptoms and a 90% stenosis of the left and a 40% stenosis of the right
internal carotid artery.
A - Right carotid endarterectomy« YOUR ANSWER
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
E - No surgical/endovascular intervention« CORRECT ANSWER
Carotid endarterectomy is indicated for patients with a symptomatic (ie transient ischaemic attack
[TIA] or amaurosis fugax) > 70% stenosis of an internal carotid artery. With regard to asymptomatic
but significant internal carotid artery stenosis, a recent randomised trial has shown that surgery will
reduce the risk of stroke from around 12% to 6% over a 5-year period. Most surgeons would therefore
not operate on patients with asymptomatic stenosis who are 80 years of age or older. Carotid stenting Page |
is still an experimental procedure and its use is confined to randomised clinical trials; previous series
have shown an unacceptably high stroke rate with carotid stenting compared with surgery. 1684
Scenario 2
An 80-year-old patient complains of amaurosis fugax in the left eye with an 80% stenosis of the right and a
50% stenosis of the left internal carotid artery.
B - Left carotid endarterectomy« YOUR ANSWER
E - No surgical/endovascular intervention« CORRECT ANSWER
In this case, the symptoms are not in the territory of the significantly stenosed carotid artery. It is
important to remember that amaurosis fugax (transient, sudden loss of vision) should occur on the
same side as the significantly diseased artery, whilst sensory or motor loss in the limbs should occur
contralateral to the diseased artery.
Scenario 3
A 60-year-old patient has no significant past medical history and a 90% stenosis of the left and a 60%
stenosis of the right internal carotid artery.
C - Right carotid artery stenting« YOUR ANSWER
E - No surgical/endovascular intervention« CORRECT ANSWER
Current guidelines (National Clinical Guideline for Stroke, 4th ed, 2012, Royal College of Physicians)
dictate the following for asymptomatic carotid artery stenosis:
1. Screening for asymptomatic carotid stenosis should not be performed.
2. Surgery or angioplasty/stenting for asymptomatic carotid artery stenosis should not routinely
be performed unless as part of a randomised trial.
3. Carotid endarterectomy or stenting should not be performed routinely in patients with
asymptomatic carotid stenosis prior to coronary artery surgery.
Scenario 4
A 72-year-old patient complains of recurrent episodes of loss of function of the left upper limb lasting for a few
minutes to an hour with 90% stenosis of both internal carotid arteries.
D - Left carotid artery stenting« YOUR ANSWER
A - Right carotid endarterectomy« CORRECT ANSWER
In this case, the 90% stenosis of the right carotid artery correlates with recurrent transient loss or
impairment of function in the contralateral (left) upper limb. Since symptoms that correlate with
significant impairment of the left carotid artery are not being experienced, most surgeons would
consider it appropriate, in a patient of this age, to carry out endarterectomy of the right carotid artery
only.
Scenario 5
A 79-year-old patient has made a good recovery from a right-sided cerebrovascular accident and has been
found to have a complete occlusion of the right and a 40% stenosis of the left internal carotid artery.
E - No surgical/endovascular intervention« CORRECT ANSWER
When assessing patients for carotid surgery, it is important to make sure that their symptoms
correlate with the significantly stenosed side. This is not the case in this patient. Carotid
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
endarterectomy is performed to prevent stroke secondary to embolisation for carotid plaque. If the
artery is occluded, there is no flow and there can therefore be no embolisation. Surgery is thus not
indicated for occluded internal carotid arteries.
36. Theme: Vascular tumours
A Angiosarcoma
B Chemodectoma
C Leiomyomas Page |
D Glomus jugulare tumour
E Kaposi’s sarcoma. 1685
Match the most appropriate feature above with the list below. Each option may be used once, more
than once, or not at all.
Scenario 1
Carotid artery
B - Chemodectoma« CORRECT ANSWER.
B – Chemodectoma:
Chemodectomas originate from paraganglionic cells at the carotid bifurcation. If untreated, 5%
metastasise within 10 years.
Scenario 2
Rapid growing, bulky
A - Angiosarcoma« CORRECT ANSWER.
Angiosarcomas usually develop in the extremities. Although they are radiosensitive and respond to
chemotherapy, radical amputation is still advised.
Scenario 3
Blue-red macule with HIV
C - Leiomyomas« YOUR ANSWER
E - Kaposi’s sarcoma« CORRECT ANSWER
Scenario 4
Buzzing sensation in head
D - Glomus jugulare tumour« CORRECT ANSWER
A glomus jugulare tumour arises at the jugular bulb. Excision is associated with palsies of cranial
nerves X, XI and XII. It should not be confused with a glomus tumour, which is the only true benign
blood vessel tumour (cavernous haemangiomas are dilated blood spaces with thin walls, and port-
wine stains/telangiectasias are capillary malformations). Most glomus tumours occur on the upper
limbs, especially the digits.
For each of the presentations below, select the most likely single treatment from the options listed
above. Each option may be used once, more than once, or not at all.
Scenario 1
A 65-year-old man presents with intermittent claudication of the left calf. His claudication distance is 50 yards Page |
(~45 m). Angiography demonstrates a 1.5-cm stenosis of the left superficial femoral artery.
A - Below-knee amputation« YOUR ANSWER 1686
F - Percutaneous balloon angioplasty« CORRECT ANSWER
Percutaneous balloon angioplasty is particularly suitable for localised stenoses and short occlusions.
Lesions in the larger proximal vessels (above knee) are technically easier to treat, with fewer
complications and better long-term results.
Scenario 2
A 73-year-old diabetic presents with critical ischaemia of the right lower leg. Angiography reveals extensive
disease of the superficial femoral, popliteal and tibial arteries. Pulse-generated, run-off assessment indicates
a good run-off in the posterior tibial artery.
B - Fasciotomy« YOUR ANSWER
C - Femorodistal bypass« CORRECT ANSWER
Femorodistal bypass using an autogenous vein graft is the treatment of choice in the second patient.
Absence of contrast in the posterior tibial, anterior tibial and common peroneal arteries on
angiography films must not be accepted as evidence of their occlusion.
Scenario 3
A 72-year-old man presents with a 4-hour history of acute ischaemia of the left leg. Clinical examination
demonstrates signs of acute ischaemia with no evidence of gangrene, mottling or neurological deficit. An
urgent angiogram reveals a complete thrombotic occlusion of the distal superficial femoral artery.
C - Femorodistal bypass« YOUR ANSWER
G - Tissue plasminogen activator (TPA) infusion (intra-arterial)« CORRECT ANSWER.
Intra-arterial thrombolysis with TPA is the treatment of choice in the third patient in view of the short
history (4 hours), angiographic findings and absence of neurological deficit.
Scenario 4
A 57-year-old smoker has a history of intermittent claudication of his right calf. His claudication distance is 0.5
mile (~0.8 km). Angiography reveals a 12-cm stenosis in the proximal superficial femoral artery. This has had
no effect on his lifestyle, work or social activities.
D - Femoropopliteal bypass« YOUR ANSWER
E - Lifestyle changes only« CORRECT ANSWER.
The initial treatment of intermittent claudication is correction of risk factors, such as diabetes,
hypertension, smoking and exercise. Younger non-smokers should have a thrombotic screen
performed on presentation. Critical ischaemia is defined by rest-pain of at least 2 weeks’ duration that
requires regular adequate analgesia, or ulceration or gangrene of the foot or toes with an ankle
pressure of < 50 mmHg or a toe pressure of < 30 mmHg.
Scenario 5
A 21-year-old motorcyclist presents with multiple injuries following a road traffic accident. Clinical examination
reveals a critically ischaemic right lower leg. The right dorsalis pedis pulse is weak. His right calf is tense and
swollen. The intracompartmental pressure is 55 mmHg. Angiography shows no discontinuity of the arterial
tree.
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
E - Lifestyle changes only« YOUR ANSWER
B - Fasciotomy« CORRECT ANSWER
The fifth patient has compartment syndrome. Urgent fasciotomy is indicated in order to save his right
leg.
From the list above, select the most likely diagnosis for the following patients who all present with
pain in the lower limb. The items may be used once, more than once, or not at all.
Scenario 1
A 32-year-old man with a long history of intravenous drug abuse attends The Emergency Department with a
4-h history of very severe pain in his left leg. On examination, the patient is in sinus rhythm. The limb is pale
and cold compared to the other side, and only the femoral pulse is present. Pulses are normal contralaterally.
A - Atherosclerosis « YOUR ANSWER
F - Embolus « CORRECT ANSWER.
The scenario describes several of the classic clinical features associated with acute limb ischaemia as
a result of arterial embolism (pain, paraesthesia, paralysis, pale, perishing with cold, pulseless). An
embolus is the passage of matter from one part of the circulation to another through a vascular lumen.
The commonest sources of arterial emboli arise in the heart (thrombus in atrial appendage secondary
to atrial fibrillation), from mural thrombus on a myocardial infarct, from aneurysms and atherosclerotic
plaques. Peripheral emboli may also arise from the heart valves. Previously, acute endocarditis on a
rheumatic heart valve was an important source, but is now rare. More commonly, peripheral emboli
occur secondary to acute bacterial endocarditis after intravenous drug abuse with contaminated
needles, as in the clinical case described.
Scenario 2
A 54-year-old woman is referred to clinic with limb pain. She describes a dull ache that is worse at the end of
the day, and that affects the right side more than the left. She has a past history of deep venous thrombosis.
On examination, varicose veins are evident in the distribution of the long sapheous system, and there is brown
pigmentation of the skin of the lower third of both legs. There is also a small ulcer superior to the medial
malleolus.
B - Buerger’s disease « YOUR ANSWER
C - Chronic venous insufficiency « CORRECT ANSWER.
Chronic venous insufficiency describes a spectrum of disease of the lower limb veins in which
venous return is chronically impaired by reflux, obstruction, or calf pump failure. This results in
sustained venous hypertension, which is associated with clinical complications such as oedema,
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]
MyPasTest: MRCS A Online - Jan Exam 2015
30. Systemic Surgery- Vascular Surgery (38Qs)
eczema, lipodermatosclerosis and ulceration. Varicose veins are usually characteristic of this
condition, and provide visual confirmation of venous reflux. However, the absence of visible varicose
veins does not exclude the presence of significant superficial reflux. The pain associated with this
condition tends to be worse following prolonged periods of standing (gravitational effects/calf pump
not functional), and is relieved by rest and elevation of the affected limb. In the case described (and
most commonly) the insufficiency is secondary to previous venous obstruction of the deep veins by
thrombosis (DVT). Page |
Scenario 3 1688
A 28-year-old man of Chinese origin with a history of calf pain induced by exercise presents to The
Emergency Department with gangrene of the left great toe. He reports a history of preceding calf pain induced
by exercise. He is a heavy smoker, but has no other risk factors for atherosclerosis. Examination reveals
absent pedal pulses on the affected side.
C - Chronic venous insufficiency « YOUR ANSWER
B - Buerger’s disease « CORRECT ANSWER.
Buerger’s disease (thromboangiitis obliterans) almost exclusively affects young men in their early 20s
or 30s who are heavy smokers. It is particularly common in men of Jewish, Arab, Indian and Chinese
origin. It has previously been considered as a variant of accelerated atherosclerosis but most now
regard it as a separate disease process. It involves progressive obliteration of distal, medium-sized
arteries of the lower limb, characterised by transmural round cell infiltration associated with intimal
proliferation. Collagen is laid down around the vessels, encasing them in a thick fibrous coat. Patients
usually present with distal gangrene, often preceded by a history of claudication. Popliteal pulses are
usually preserved, but pedal pulses are absent. Arteriography shows normal proximal vessels and
distal occlusions with ‘corkscrew’ collaterals. Biopsy of the occluded vessel provides histological
confirmation of the diagnosis.
Editor:
Dr Mohammed Shamsul Islam Khan
MBBS (CMC); FCPS-II (Neuro-Surgery)
Medical Officer, Clinical Neuro-Surgery
National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh.
Mobile: +880 1713 455 662, +880 1685 811979.
E-mail: [email protected]
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
Dr Mohammed Shamsul Islam Khan, Medical Officer, Clinical Neuro-Surgery, National Institute of Neuro-Sciences and Hospital
Sher-E-Bangla Nagar, Dhaka-1207, Bangladesh. Mobile: +880 1713 455 662, +880 1685 811979. E-mail: [email protected]