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Acute Myeloid Leukemia (Drug Study)
Acute Myeloid Leukemia (Drug Study)
Francisco
BSN III – B (group B3)
DRUG STUDY
DRUG NAME DATE/TIME/ USES ACTION INDICATION SIDE EFFECTS NURSING RESPONSIBLITIES
FREQUENCY OF
ADMINISTRATION
It is used Causes It is indicated for Redness/pain/ Assessment & Drug Effects
Azacitidine 3/11/2021 8:00am to treat changes in treatment of bruising at the
myelodys DNA in patients with the injection Monitor for S&S of drug toxicity in
300 mg PO q day on days plastic those with renal insufficiency.
abnormal following site, tiredness,
Drug 1 - 14 syndrome Lab tests: Obtain LFTs and serum
Classification: (a group blood-forming myelodysplastic diarrhea, dizziness,
creatinine before initiation of therapy;
Cytotoxic of cells in the syndrome subtypes: trouble sleeping, monitor CBC with differential before
chemotherapy conditions bone marrow, refractory anemia constipation, nausea, each treatment cycle and prn.
drugs/ demethy in which resulting in or refractory vomiting, mouth Withhold drug & notify physician for
lation agents the bone restoration of anemia with ringed sores, dry S&S of hepatic or renal insufficiency;
marrow normal sideroblasts (if skin, headache, and lab values that indicate leukopenia,
Generic produces neutropenia, thrombocytopenia, or
function to accompanied by loss of appetite may
name: vidaza blood hepatic or renal insufficiency; or
cells that tumor- neutropenia or occur.
serum bicarbonate levels less than 20
are suppressor thrombocytopenia mEq/L.
misshapen genes that are or requiring
and does responsible for transfusions), Patient & Family Education
not regulating cell refractory anemia
produce differentiation with excess blasts, Promptly report S&S of infection or
enough indication of unusual bleeding
and growth. refractory anemia
healthy tendencies (e.g., dark, tarry stools and
blood with excess blasts
easy bruising).
cells). in bone marrow
Men should not father a child while
taking this drug.
DRUG NAME DATE/TIME/ USES ACTION INDICATION SIDE EFFECTS NURSING RESPONSIBLITIES
FREQUENCY OF
ADMINISTRATION
It is used It binds to and It is indicated in Common side Assessment & Drug Effects
Venetoclax 3/11/2021 8:00am to slow or inhibiting combination with effects of Venclexta
stop the BCL-2, which azacitidine, for the include: Monitor for S&S of drug toxicity in
Drug 20 mg PO q Day for growth treatment of newly- those with renal insufficiency.
is a protein low white blood cell
Classification: Week 1 of cancer diagnosed acute Monitor complete blood count
Cytotoxic cells. found on myeloid leukemia count (neutropenia),
chemotherapy cancerous (AML) in adults 75 diarrhea, nausea, Patient & Family Education
drug lymphocyte years or older. low blood iron
cells. Venetocl (anemia), upper Men should be advised of the
Generic ax causes the respiratory tract possibility of infertility and sperm
name: breakdown of infection, low levels banking options.
Venclexta Patients must avoid grapefruit
the of platelets in the
lymphocytes blood products, Seville oranges, and starfruit
while taking venetoclax.
that cause (thrombocytopenia),
Patients should contact their oncology
Chronic fatigue, nausea, care providers before taking any new
Lymphocytic vomiting, prescription or over-the-counter
Leukemia constipation, fatigue, drugs.
(CLL). fever, swelling in the Teach patients how to monitor for and
extremities, back decrease the risk of infection and
pain headache, and, bleeding, including when to contact
cough their healthcare providers.
Instruct patients to take venetoclax at
a similar time each day with a meal
and water. If they are within eight
hours of a missed dose, they should
take it as soon as possible. If it has
been more than eight hours, they
should wait until the next scheduled
dose. If they vomit after taking a dose,
they should not repeat the venetoclax
but wait until their next scheduled
dose.