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Antiparasitic Drug Ivermectin Kills Coronavirus in 48 Hours
Antiparasitic Drug Ivermectin Kills Coronavirus in 48 Hours
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Novel Coronavirus SARS-CoV-2 Colorized scanning electron micrograph of an apoptotic cell (green) heavily infected with
SARS-COV-2 virus particles (yellow), isolated from a patient sample. Image captured at the NIAID Integrated Research
Facility (IRF) in Fort Detrick, Maryland. Credit: NIAID
The drug, Ivermectin, an antiparasitic medicine, is an inhibitor of the virus SARS-CoV-2 in-vitro and can e ectively
cause a reduction in virus at 48 hours in cell cultures. The FDA-approved drug can be used for repurposing to
treat patients a ected by COVID-19, which has spread to 184 countries and territories.
The researchers at Monash University in Melbourne, Australia, have published their study in the journal Antiviral
Research, showing how this already widely-used drug may help combat the current global pandemic rippling
across continents.
"We found that even a single dose could essentially remove all viral RNA by 48 hours and that even at 24
hours, there was a signi cant reduction in it," Dr. Kylie Wagsta of the Monash Biomedicine Discovery
Institute, said.
"Ivermectin is very widely used and seen as a safe drug. We need to gure out now whether the dosage you
can use it in humans will be e ective – that's the next step," Dr. Wagsta added.
The researchers, however, cautioned that the tests performed in the
study were in vitro, and humanMEDICAL HOME
trials are LIFE SCIENCES HOME
still needed to determine the Become a Member Search...
e cacy and safety of the drug against the coronavirus. Ivermectin has
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also shown e ectiveness in vitro COVID-19
against Newsof other
a wide range Health A-Z Drugs
viruses, Medical Devices
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may be White Papers
bene cial in More...
such as the in uenza virus, Zika virus, and the human COVID-19 treatment
immunode ciency virus (HIV). Climate change may have
contributed to the COVID-19
pandemic
Repurposing Ivermectin
P zer-BioNTech SARS-CoV-2
Ivermectin is an approved drug to treat parasitic conditions, such as vaccine e ective for wide range
rosacea, head lice, and scabies. It was developed in 1975 and has been of Covid-19–related outcomes
widely used across the globe since the early 1980s.
"In times when we're having a global pandemic, and there isn't an approved treatment, if we had a
compound that was already available around the world, then that might help people sooner. Realistically,
it's going to be a while before a vaccine is broadly available," Dr. Wagsta explained.
Though the mechanism of action by which Ivermectin works on the coronavirus is still unknown, the drug works
on other viruses by stopping them from inhibiting down the host cells' ability to detect and ght them.
Ivermectin, therefore, warrants further investigation for possible bene ts in humans. Further trials should be
performed to make sure the drug is e ective. If it is e ective on humans with coronavirus, it can be widely used
to treat a ected populations since it already went through approval by the U.S. Food and Drug Administration
(FDA).
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Many countries are unprepared for the coming of the coronavirus disease, which has emerged in China in
in ammation
December 2019. Since then, it has spread to most countries across the globe, touching all continents except
Antarctica.
Sources:
Monash University. (2020). Possible coronavirus drug identi ed by Monash University scientists. One dose of SARS-CoV-2 vaccine
candidate boosts neutralizing
https://www.monash.edu/discovery-institute/news-and-events/news/2020-articles/possible-coronavirus-
antibody response in COVID-19
drug-identi ed-by-monash-university-scientists convalescents
Coronavirus COVID-19 Global Cases by the Center for Systems Science and Engineering (CSSE) at Johns
Hopkins University (JHU) -
A SARS-CoV-2 spike protein
https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf
adjuvant vaccine candidate
6 produces durable rapid protection
Journal reference: in vivo
Caly, L., Druce, J., Catton, M., Jans, D., and Wagsta , K. (2020). The FDA-approved Drug Ivermectin inhibits the
replication of SARS-CoV-2 in vitro. Antiviral Research.
https://www.sciencedirect.com/science/article/pii/S0166354220302011 Newsletters you may be interested in
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Posted in: Drug Trial News | Medical Research News | Disease/Infection News
Tags: Biomedicine, Cell, Cell Culture, Compound, Coronavirus, Coronavirus Disease COVID-19, E cacy, Electron, Head Lice, HIV,
HIV-1, Immunode ciency, in vitro, In uenza, Ivermectin, Medicine, Micrograph, Pandemic, Research, Respiratory, RNA, Rosacea,
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SARS-CoV-2, Scabies, Severe Acute Respiratory Syndrome, Vaccine, Virus, Zika Virus (Subscribe or Preview)
Comments (6)
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laypeople
Comments
It is a publicized well known fact that high heat kills the virus, doesn't
Pamela Newton says:
April 9, 2020 at 8:30 AM
It is a publicized well known fact that high heat kills the virus, doesn't help spread it as your article states. That is why
it is encouraged to drink hot liquids. Your article said it spreads in high heat. It likes cold environments instead. You need to
correct your article.
Reply 1 0
Reply 1 0
It smacks too much of that sh tank cleaner "drug' that was killing too many people earlier this year.
Reply 1 0
Reply 2 0
Old News MEDICAL HOME LIFE SCIENCES HOME Become a Member Search...
Lucy Redding says:
December 30, 2020 at 12:54 PM
About
This report does not go far COVID-19 Newssince
enough, probably Health
it wasA-Z
from Drugs Medical more
April 2020. Wish Devices Interviews
people (especially White Papers More...
reporters and DOCTORS) saw this back then. Maybe the FLCCC would have more support. Soooo much more is
known now!
Reply 1 0
Lancet on Ivermectin
L. G. Bloom says:
January 24, 2021 at 5:09 PM
www.thelancet.com/.../fulltext
Reply 0 0
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