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Antiparasitic drug Ivermectin kills coronavirus in 48

hours
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Simple trick to clean earwax

By Angela Betsaida B. Laguipo, BSN Apr 6 2020
Earwax can cause hearing loss
and memory loss. Try this simple
x to remove earwax.
Around the world, scientists race to develop a vaccine or treatment against the coronavirus disease (COVID-19),
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Now, a team of researchers has
found that a drug already available around the world can kill the coronavirus in a lab setting in just 48 hours. Trending Latest Top Health
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Novel Coronavirus SARS-CoV-2 Colorized scanning electron micrograph of an apoptotic cell (green) heavily infected with
SARS-COV-2 virus particles (yellow), isolated from a patient sample. Image captured at the NIAID Integrated Research
Facility (IRF) in Fort Detrick, Maryland. Credit: NIAID

The drug, Ivermectin, an antiparasitic medicine, is an inhibitor of the virus SARS-CoV-2 in-vitro and can e ectively
cause a reduction in virus at 48 hours in cell cultures. The FDA-approved drug can be used for repurposing to
treat patients a ected by COVID-19, which has spread to 184 countries and territories.

The researchers at Monash University in Melbourne, Australia, have published their study in the journal Antiviral
Research, showing how this already widely-used drug may help combat the current global pandemic rippling
across continents.

Reduced COVID-19 viral RNA

The team worked with the Peter Doherty Institute of Infection and Immunity. They showed that Ivermectin
reduced COVID-19 viral RNA present in cell culture by as much as 93 percent after 24 hours and by 99.8 percent
after 48 hours, at around a 5,000-fold reduction in coronavirus RNA, hinting that the medicine can potentially
eradicate the virus.

"We found that even a single dose could essentially remove all viral RNA by 48 hours and that even at 24
hours, there was a signi cant reduction in it," Dr. Kylie Wagsta of the Monash Biomedicine Discovery
Institute, said.

"Ivermectin is very widely used and seen as a safe drug. We need to gure out now whether the dosage you
can use it in humans will be e ective – that's the next step," Dr. Wagsta added.
The researchers, however, cautioned that the tests performed in the
study were in vitro, and humanMEDICAL HOME
trials are LIFE SCIENCES HOME
still needed to determine the Become a Member  Search... 
e cacy and safety of the drug against the coronavirus. Ivermectin has
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also shown e ectiveness in vitro COVID-19
against Newsof other
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such as the in uenza virus, Zika virus, and the human COVID-19 treatment
immunode ciency virus (HIV). Climate change may have
contributed to the COVID-19
pandemic
Repurposing Ivermectin
P zer-BioNTech SARS-CoV-2
Ivermectin is an approved drug to treat parasitic conditions, such as vaccine e ective for wide range
rosacea, head lice, and scabies. It was developed in 1975 and has been of Covid-19–related outcomes
widely used across the globe since the early 1980s.

"In times when we're having a global pandemic, and there isn't an approved treatment, if we had a
compound that was already available around the world, then that might help people sooner. Realistically,
it's going to be a while before a vaccine is broadly available," Dr. Wagsta explained.

Though the mechanism of action by which Ivermectin works on the coronavirus is still unknown, the drug works
on other viruses by stopping them from inhibiting down the host cells' ability to detect and ght them.

Ivermectin, therefore, warrants further investigation for possible bene ts in humans. Further trials should be
performed to make sure the drug is e ective. If it is e ective on humans with coronavirus, it can be widely used
to treat a ected populations since it already went through approval by the U.S. Food and Drug Administration
(FDA).

Latest News
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Many countries are unprepared for the coming of the coronavirus disease, which has emerged in China in
in ammation
December 2019. Since then, it has spread to most countries across the globe, touching all continents except
Antarctica.

Fire ghters — ‘health care providers

The United States reports the highest infections, with more than 368,000 people a ected by the virus. It has a
on a truck’ — signal pandemic
staggering 10,923 deaths. Italy has the highest number of deaths, with its death toll reaching 16,523, while Spain burnout
has more than 136,000 con rmed cases and 13,341 deaths. Canada has more than 16,000 con rmed cases, while
Germany, France, and China have more than 103,000, 98,000, and 82,000 cases, respectively.

One school district’s struggle over

The coronavirus has dramatically a ected the United Kingdom and Australia also, with more than 52,000 and public health, parents and politics
more than 5,700 cases, respectively.  

Sources:
Monash University. (2020). Possible coronavirus drug identi ed by Monash University scientists. One dose of SARS-CoV-2 vaccine
candidate boosts neutralizing
https://www.monash.edu/discovery-institute/news-and-events/news/2020-articles/possible-coronavirus-
antibody response in COVID-19
drug-identi ed-by-monash-university-scientists convalescents
Coronavirus COVID-19 Global Cases by the Center for Systems Science and Engineering (CSSE) at Johns
Hopkins University (JHU) -
A SARS-CoV-2 spike protein
https://gisanddata.maps.arcgis.com/apps/opsdashboard/index.html#/bda7594740fd40299423467b48e9ecf
adjuvant vaccine candidate
6 produces durable rapid protection
Journal reference: in vivo
Caly, L., Druce, J., Catton, M., Jans, D., and Wagsta , K. (2020). The FDA-approved Drug Ivermectin inhibits the
replication of SARS-CoV-2 in vitro. Antiviral Research.
https://www.sciencedirect.com/science/article/pii/S0166354220302011 Newsletters you may be interested in

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Posted in: Drug Trial News | Medical Research News | Disease/Infection News

Tags: Biomedicine, Cell, Cell Culture, Compound, Coronavirus, Coronavirus Disease COVID-19, E cacy, Electron, Head Lice, HIV,
HIV-1, Immunode ciency, in vitro, In uenza, Ivermectin, Medicine, Micrograph, Pandemic, Research, Respiratory, RNA, Rosacea,
Infectious Diseases
SARS-CoV-2, Scabies, Severe Acute Respiratory Syndrome, Vaccine, Virus, Zika Virus (Subscribe or Preview)

Comments (6)

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Written by

Angela Betsaida B. Laguipo

Angela is a nurse by profession and a writer by heart. She graduated with honors (Cum Laude)
for her Bachelor of Nursing degree at the University of Baguio, Philippines. She is currently
completing her Master's Degree where she specialized in Maternal and Child Nursing and
worked as a clinical instructor and educator in the School of Nursing at the University of Baguio.
 MEDICAL HOME LIFE SCIENCES HOME Become a Member  Search... 
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Read in: English

Citations 

Suggested Reading

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favors adaptive evolution of protection against severe from Siemens Healthineers to COVID-19 treatment?
SARS-CoV-2 COVID-19, nds study receives special approval in
Germany for self-use by
laypeople

Comments

It is a publicized well known fact that high heat kills the virus, doesn't
Pamela Newton says:
April 9, 2020 at 8:30 AM
It is a publicized well known fact that high heat kills the virus, doesn't help spread it as your article states. That is why
it is encouraged to drink hot liquids. Your article said it spreads in high heat. It likes cold environments instead. You need to
correct your article.

Reply 1 0

Correction, a link to a related story, says it spreads in high heat, when

Pamela Newton says:
April 9, 2020 at 8:36 AM
Correction, a link to a related story, says it spreads in high heat, when it is heat that destroys it instead. It spread in
winter time.

Reply 1 0

Be Careful What You Wish For...You May Get It

Doug Graham says:
December 28, 2020 at 10:22 PM
If this were true, it would be reported by CBS, NBC, ABC, MSNBC, etc. I'll wait until it's been peer-reviewed by real
medical professionals (UW Medical Center, Johns Hopkins University, Mayo Clinic, CDC, etc.), and not some unknown BSN with
an unproven opinion, before I'll ever consider it's e cacy.

It smacks too much of that sh tank cleaner "drug' that was killing too many people earlier this year.

Reply 1 0

Ivermectin e ective in clinical trials.

Janaia Donaldson says:
December 29, 2020 at 11:56 PM
Dig deeper in your research, Angela: Doctors in the US & UK have been using Ivermectin on patients quite
successfully. Check out https://covid19criticalcare.com. You can download their report "Review of the Emerging Evidence
Demonstrating the E cacy of Ivermectin in the Prophylaxis and Treatment of COVID-19." From that review: "Despite the
growing list of failed therapeutics in COVID-19, the FLCCC recently discovered that ivermectin, an anti-parasitic medicine, has
highly potent real-world, anti-viral, and anti-in ammatory properties against SARS-CoV-2 and COVID-19. This conclusion is
based on the increasing study results reporting e ectiveness, not only within in-vitro and animal models, but also in
numerous clinical trials from centers and countries around the world."

Reply 2 0
 Old News MEDICAL HOME LIFE SCIENCES HOME Become a Member  Search... 
Lucy Redding says:
December 30, 2020 at 12:54 PM
About
This report does not go far COVID-19 Newssince
enough, probably Health
it wasA-Z
from Drugs Medical more
April 2020.  Wish Devices Interviews
people (especially White Papers More...
reporters and DOCTORS) saw this back then. Maybe the FLCCC would have more support. Soooo much more is
known now!

Reply 1 0

Lancet on Ivermectin
L. G. Bloom says:
January 24, 2021 at 5:09 PM
www.thelancet.com/.../fulltext

Reply 0 0

The opinions expressed here are the views of the writer and do not necessarily re ect the views and opinions of News Medical.

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