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A.K.T.U.

Lucknow
Rajarshi Rananjay Sinh College of Pharmacy
Maharaja Bhagwan Baksh Sinh Nagar, Amethi, Sultanpur (U.P.)-227405
B Pharm Ist Year IInd Sem Even Sem (2020-21)

Subject Name – Pathophysiology Subject code –BP204T

1. True about apoptosis are all except?


A. Inflammation in present
B. Chromosomal breakage
C.Clumping of chromatin
D.Cell shrinkage
Answer (a)
2. Programmed cell death is known as?
A. Cytolysis
B. Apoptosis
C. Necrosis
D. Proptosis
Answer(b)
3. Hypertrophy of a muscle due to
A. Increase in number of cells
BIncrease in size of cells
C. Decrease in number of cells
D. Abnormal shape of cells
Answer(b)
4. Apoptosis is?
A. Cell degradation
B. Type of cell injury
C. Cell regeneration
D. Cell activation
Answer (b)
5.Dysplasia refers to
A. Change in morphology
B. Change in number
C .Change in cell type
D.Change in cell type
Answer(a)
6. Liquefactive necrosis is seen in?
A. Heart
B. Brain
C. Lung
D. Spleen
Answer(b)
7. Macrophages are derived from
A.Monocytes
B.T cells
C.B cells
D.Plasma cells
Answer(a)
8. Macrophages may secrete
A. Histamine
B. Serotonin
C. Prostaglandins
D. none of the above
Answer(c)
9. Pain in inflammation is mediated by
A.Histamine
B.Serotonin
C.Thromboxane
D.Bradykinin
Answer (d)
10 .The formation of blood clot is known as which of the following
A.Coagulation
B.Chemotaxis
C.Leucopoiesis
D.Erythropoiesis
Answer(a)
11. Which of the following is not associated with inflammation?
A. Redness
B.Swelling
C. Decreased capillary permeability
D. Vasodilation
Answer (c)
12. Which is not one of the four characteristic symptoms of inflammation?
A. Redness.
B. Swelling
C. Pain
D. Cyanosis
Answer (d)

13. What is the function of blood platelets


A. Aid in coagulation of blood
B.Ingest bacteria
C.Carry hemoglobin
D.Transport CO 2
Answer (a)

14. In which part of the respiratory system, gaseous exchange takes place?
A.Alveoli
B.Pharynx
C.Larynx
D. Trachea
Answer(a)
15. Which of the following are parts of the human respiratory system?
A.Trachea
B.Diaphragm
C.The lungs
D.All of the above
Answer(d)
16. Heart attack occurs when there is blood clotting in
A. Renal arteries
B. Mesenteric arteries
C.Hepatic arteries
D. Coronary arteries
Answer(d)
17. The tiny air sacs present in human lungs is called_______.
A.Alveoli
B.Bronchus
C.Bronchioles
D.All of the above
Answer(a)
18. Which of the following functions by filtering and keeping the mucus and dirt away
from our lungs?
A.Cilia
B.Bronchioles
C.Hairs in the lungs
D.All of the above
Answer(a)
19 .The total numbers of alveoli present in the human lungs is estimated to be around
______.
A.1 billion
B.800 million
C.500 million
D.1500 million
Answer(c)
20. The exchange of gases between the external environment and the lungs______.
A.Respiration
B.External respiration
C.Cellular respiration
D.None of the above
Answer(b)
21. The maximum volume of air contained in the lung by a full forced inhalation is called
_________.
A.Tidal volume
B.Vital capacity
C.Ventilation rate
D.Total lung capacity
Answer(d)
22 .The windpipe is also called the ________.
A.Larynx
B.Lungs
C.Trachea
D.Oesophagus
Answer(c)
23. Which of these statements is true about internal respiration?
A.Production of ATP
B.Exchange of gases between the bloodstream and tissue cells
C.Exchange of gases between alveoli and the bloodstream
D.Breathing between the atmosphere and the alveoli
Answer(b)
24.The functional unit of the kidney is called a
A.Glomerulus.
B.Nephron.
C. Corpuscle.
D.Calyx.
Answer(b)

25. All of the following belong to the urinary system except:


A.Urethra.
B. Ureter.
C.Bladder.
D.Prostate.
Answer(d)

26. The structure that connects a kidney to the urinary bladder is the
A.Ureter.
B.Urethra.
C.Renal pelvis.
D.Collecting duct.
Answer(a)

27.The kidneys are:


A .Help regulates blood volume.
B.Help control blood pressure.
C.Help control PH.
D .All of the above is correct.
Answer(d)

28. The medical term for chest pain is………


A.Angina
B.There is no medical term for chest pain
C.Flutter
D.Arrhythmia
Answer(a)

29. Sickle cell anemia is caused by replacement of glutamic acid in beta globin chain of HB
by
A. Arginine
B. Valine
C. Histidine
D. Leucine
Answer(b)

30. Hemophilia is also known as except


A.Disease of kings
B.Bleeder disease
C.Disease of Hapsburg
D.Christmas disease
Answer(d)

31. Anemia is a common condition, what happen when a person has anemia?
A.The produces too much iron
B.The body does not have enough red blood cells
C.The blood become thick
D.Too many white blood cells are produces
Answer(b)

32. How does anemia affect the body?


A.The blood does not deliver enough oxygen to the body
B.Blood becomes thin
C.Tissues retain fluids
D.None of the above
Answer(a)

33. Which of these sign of anemia


A.Pale gums
B.Dark circles under the eye
D.Numbness in hand and feet
Answer(a)

34.Most of the iron in the red blood cells is located in


A.Ferritin
B.Myoglobin
C.Hemoglobin
C.Cytochromes
Answer(c)

35. High intakes of iron in certain people can leads to


A.Liver damage
B.Anemia
C.Nerve damage
D.Hypertension
Answer(a)

36. Person unable to absorb dietary vitamin B12 suffer from


A.Iron deficiency anemia
B.Pernicious anemia
C.Aplastic anemia
D.Pellagra
Answer(c)

37.The risk factor for type 2 diabetes mellitus include …..


A.Family history
B.Being a member of high risk population
C.Being overweight
D.All of the above
Answer(d)
38. The risk factor for type 1 diabetes mellitus include …..
A.Being overweight
B. Inactivity
C.Family history
D.All of the above
Answer (c)

39. Having a high blood glucose level is called


A.Hyperglycemia
B.Hypoglycemia
C.Diabetic ketoacidosis
D.Microsome
Answer (a)
40. Physical symptoms of type 1 diabetes mellitus include …..
A.Unexpected weight loss
B.Increased thirst
C.Frequent urination
D.All of the above
Answer (d)

41. After a meal, blood glucose level increase and stimulate the secretion of which hormone
A.Insulin
B.Glycogen
C.Pancreatisome
D. Glucagon
Answer(a)

42. The most effective treatment for premature ejaculation


A.Benzodiazepine medication
B.Brief dynamic psychotherapy
C.Prestige suggestion
D.The squeeze technique

Answer(d)

43.The part of brain most affected in Parkinson disease is


A.Corpus stritum
B.Putamen
C.Substantianigra
D.Thalmus
Answer(c)

44 .The common cause of chronic progressive Parkinsonism is


A.Gene mutation
B.Toxins
C.Trauma
D.All of the above
Answer(d)

45.IBD is inflammatory disorder of which part


A. Liver
B. Spleen
C. Intestine
D. Lung
Answer (c)

46.How isAlzheimer’s diagnosed


A. Mental status test
B .Blood test
C.Neurological tests
D.All of the above
Answer(d)

47. Sign of Alzheimer’s include which of the symptoms


A.Loss of memory
B.Increase in irritability
C.Restlessness
D.All of the above
Answer(d)

48. Mood disorder is seen in


A.Hysterical state
B.Borderline personality state
C.Paranoid state
D.Schizoid state
Answer(b)
49. Jaundice is also known as
A.Lacterus
B.Hemophilia
C.Anemia
D.Hypercholesterolemia
Answer(a)

50. Depression is an:


A.Affective disorders
B.Organic disorder
C.Mood disorders
D.Dissociate disorder
Answer(c)

51. The commonest psychiatric disorder is


A.Dementia
B.Schizophrenia
C.Paranoia
D.Depression
Answer(d)

52. About 70% of people with epilepsy the cause are …..
A.Head trauma
B.Brain tumors
C.Unknown
D.Stroke
Answer(c)

53.In pancrease the insulin is secreted from


A. Alpha cells
B. Beta cells
C. Delta cells
D. all of the above
Answer(b)

54. The preferred noninvasive test to confirm H .pylori eradication is


A.A stool antigen test
B.A whole blood antibody detection test
C.A serologic antibody detection test
D.A urea breath test
Answer(d)

55. The most frequent cause of UGI bleeding is


A. Esophageal varices
B.Peptic ulcer disease
C.Angiomata
D.Gastritis
Answer (b)

56 Gout is a disorder of
A. Metabolism
B. Catabolism
C. Children
D. The nervous system
Answer(a)

57.Hepatitis A
A.Is a benign self-limiting disease
B.Has a mean incubation period of 1-4 months
C.Frequently cause fulfillment hepatitis
D.Igm is not a reliable maker of acute infection
Answer(b)

58.Hepatitis B can produce all of the following except


A.Acute hepatitis
B.Helper independent latent infection
C.Non progressive chronic hepatitis
D.An asymptomatic carrier state
Answer (b)

59. Antiviral drug therapy for HIV infection


A.Eradicates HIV
B.Once the virus is suppressed, progressive loss of CD+T cell is halted
C.Over years the peripheral CD+T cell count slowly decreases
D.Use of these drugs has not affected death rates from AIDS
Answer(b)

60. The major routes of transmission of HIV are


A.Sexual transmission
B.Parenteral transmission
C.Mother to infant transmission
D.Fecal oral transmission
Answer(d)

61.Which of the following disease characteristically cause the fatty change in lever?
A.Hepatitis B virus infection
B.Wilson disease
C.Hepatitis C virus infection
D.Chronic alcoholism
Answer(d)

62. Which of the following is the most likely site for acute Mon articular gouty arthritis?
A.First metatarsophalangeal joint
B.Instep
C.Hel
D.Knee
Answer(a)

63. Jaundice is caused due to


A. Excess of uric acid in blood
B.Excess of hemoglobin in the blood
C.Excess of potassium in the blood
D.Excess of bilirubin in the blood
Answer(d)

64. Risk factors for the development of osteoarthritis include


A.Smoking
B.Participation in running
C.Being underweight
D.Advanced age
Answer (d)

65 Anemia rises due to deficiency of


A. Iron
B .Vitamin B12
C .Folic acid
D .All of the above
Answer(d)

66. Genotoxic carcinogens affect


A.Cell wall
B.RNA
C.DNA
D.Mitochondria
Answer (c)

67. Which of the following is not a characteristic of cancer cells?


A.Loss of cell control
B.Transplant ability
C.loss of contact inhibitor
D.All are characteristics
Answer (d)

68. Which of the following contribute to causing cancer?


A.A mutation in a gene that slows the cell cycle
B.Faulty DNA repair
C. loss of control over telomere length
D.all of the above
Answer(d)

69.Cancer cell can easily be destroyed by radiation


A.Fast mutation
B.Rapid cell mutation
C.Lack of mutation
D.Lack of oxygen
Answer (b)

70. Cancer is caused by


A.Uncontrolled mitosis
B .A Uncontrolled meiosis
C.Rapturing of cell
D.Loss of immunity of cell
Answer(a)

71.Tuberculosis (TB) is caused by


A. Mycobacterium tuberculosis
B. Salmonella typhi
C. Mycobacteriumleprae
D. Treponema palladium
Answer(a)

72 .Typhoid fever is transmitted by


A.Contaminated food and water
B.Droplet nuclei
C.Infected syringes and needles
D.Sexual intercourse
Answer (a)

73.The most common symptoms of typhoid is


A.Fever
B.Abdominal pain
C.Haloperidol
D.Diarrhea
Answer (a)

74. Tuberculosis is transmitted through


A. Infected water
B. Infected hand
C. Infected blood
D. Infected air
Answer(d)

75. The following test is not used for diagnosis of leprosy


A. Lepromin test
B. Slit skin smear
C.FNAC
D. Skin biopsy
Answer(a)

76. Which drug is not used to treatment of leprosy?


A. Rifampicin
B. Dapsone
C. Clofamaine
D. isoniazid
Answer(d)

77.All of the following aspect oneis CD4+ T cells


A. Monocyte
B.T helper cell
C. Cytotoxic cell
D. Macrophages
Answer(b)

78. What kind of virus is HIV?


A. Rotavirus
B. Retrovirus
C. Rhinovirus
D. Coronavirus
Answer(b)

79. How is a person tested for syphilis?


A.A blood test
B.A urine test
C.A breathalyzer test
D. All of the above
Answer(a)

80. Sexually transmitted disease is ……..


A. Rare
B.A major worldwide problem
C. Cause on by bacteria
D. None of these are correct
Answer(b)

81.The bacterium Neisseria gonorrhea causes


A. Botulism
B. Strep throat
C. Gonorrhea
D. Syphilis
Answer (c)

82. Syphilis has …….stage


A. One
B. Two
C. Three
D. Four
Answer(c)

83. Which of the following is not a symptom of syphilis?


A. A hard cancer sore
B.A sashes on the skin including the palm and soles
C.A thick yellow discharge
D. Large ulcer called gummas
Answer(c)

84. The role of reverse transcription is to


A. Make RNA and DNA
B. Make DNA and RNA
C. Make capsid
D. Make a provirus
Answer(c)

85. The over production of thyroid hormones is called as


A. Hyperthyroidism
B. Hypothyroidism
C. Hypocalcemia
D. All of the above
Answer(a)

86. Increase in size of parenchymal cell is called as


A.Hypertrophy
B.Atrophy
C.Hyperplasia
D.Metaplasia
Answer (a)

87. The condition in which urine production is decreased below 500 ml per day
is called as
A.Polyuria
B.Oliguria
C.Anuria
D.Etruria
Answer(b)

88. The major location of occurrence of Emphysema is


A.Bronchus
B .Trachea
C.Bronchioles
D.Acinus
Answer(c)

89. Which of the following Hepatitis is having the longest incubation period
A. Hepatitis A
B .Hepatitis B
C .Hepatitis C
D .Hepatitis D
Answer(c)
90.The duration of the initial asymptomatic incubation period in typhoid fever
Is about
A. 2 days
B. 2 weeks
C. months
D.2 years
Answer(b)

91. The study of causes of diseases is known as


A. Epidemiology
B. Etiology
C. Histology
D. Morphology
Answer(b)

92. The causative organism for syphilis is


A.Salmonella typhi
B. Vibrio cholera
C.Treponemapalladium
D.Clostridium tetani
Answer(c)

93.Hansen’s disease is also known as


A. Leprosy
B. Typhoid
C. Asthma
D. Gonorrhea
Answer(a)

94. Loss of appetite is known as


A. Insomnia
B. Nausea
C. Anorexia
D. Alopecia
Answer(c)

95.Hypercalcemia indicates high serum levels of


A .Sodium
B.Potassium
C .Chloride
D.Calcium
Answer(d)

96. Decrease oxygen concentration of blood is called as


A.Anemia
B.Hypoxia
C.Hypercapnia
D .Cyanosis
Answer(b)

97. Caseous necrosis is the hallmark of


A .Myocardial infraction
B .Cerebral infract
C .Tuberculosis
D .Fungal infection
Answer(c)

98. Phagocytosis includes all of the following steps except


A.Endocytosis
B .Exocytosis
C .Antibody formation
D.Enzymatic digestion
Answer(c)

99. Duodenal peptic ulcers are associated with


A. Achlorhydria
B. Hypochlorhydria
C. Normochlorhydria
D. Hyperchlorhydria
Answer(d)

100. Necrosis means?

A. Efflux of calcium

B. Swelling of cell

C .Enzymatic degradation

D .Fat deposition

Answer(c)

101. Asthma is defined as chronic inflammation disease of………………..


A.Heart
B.Airway
C.Arteries
D.None of the above
Answer(c)
102. Leukocytes are
A.RBC
B Platelets
C.WBC
D.Toxins
Answer (c)

103. Dolor means……….


A .Redness
B .Swelling
C.Tumor
D .Pain
Answer (d)

104. Leucocytes migrates in extracellular space through gaps between endothelium


referred as
A.Transduction
B.Locomotion
C .Emigration
D.Transfer
Answer(c)

105. Rubber means……….

A .Redness

B .Swelling

C .Tumor

D.Pain

Answer (a)

106. Vitamin B12 is also known as

A. Riboflavin

B. Cynocobalamin

C. Pyridoxine
D. None of the above

Answer (b)

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