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Pediatric Dentistry

5 th
Year

Lec. 11
Treatment of Immature
Permanent Teeth with
Pulpal Necrosis
Assistant Professor
Aseel Haidar
Lec.11 Pedodontics Fifth stage

Assist. Prof. Dr. Aseel Haidar


Treatment of Immature Permanent Teeth with
Pulpal Necrosis

Apexification
The conventional treatment of pulpless anterior teeth usually requires apical
surgery. There is a less traumatic endodontic therapy called apexification, which has been
found to be effective in the management of immature, necrotic permanent teeth. The
apexification procedure should precede root canal therapy in the management of teeth
with irreversibly diseased pulps and open apices. The procedure has been demonstrated
to be successful in repeated clinical trials stimulating the process of root end
development, which was interrupted by pulpal necrosis, so that it continues to the point of
apical closure. Often a calcific bridge develops just coronal to the apex. When the closure
occurs, or when the calcific “plug” is observed in the apical portion, routine endodontic
procedures may be completed; the possibility of recurrent periapical pathosis is thus
prevented.

a) A

preoperative
radiograph of maxillary left central incisor with an open apex (b) Radiographic evaluation of Mineral trioxide
aggregate level (c) Follow-up after 6 months (d) Follow-up at 18 months
(https://jbcd.uobaghdad.edu.iq/index.php/jbcd/article/view/525)

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Lec.11 Pedodontics Fifth stage

Regenerative Endodontic Procedures (REPs)

It is defined as biologically based procedures designed to replace damaged


structures, which include dentin, root structures, and cells of the pulp–dentin complex.
These procedures provide a biological alternative to induce continuous root development
and reduce the risk of fracture associated with traditional treatments of immature teeth
with necrotic pulps, such as calcium hydroxide or MTA or biodentin apexification, where
the root remains thin and weak.

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Lec.11 Pedodontics Fifth stage

REACTION OF THE PULP TO VARIOUS


CAPPING MATERIALS

ZINC OXIDE–EUGENOL
Zinc oxide–eugenol was used more often than any other pulp capping material
before calcium hydroxide came into common use. Although dentists have apparently had
good clinical results with the use of zinc oxide–eugenol, it is not recommended as a direct
pulp-capping material.

CALCIUM HYDROXIDE
Calcium hydroxide used as a biological dressing. Because of its high
alkalinity (pH 12), it is so caustic that when it is placed in contact with vital pulp tissue,
the reaction produces a superficial necrosis of the pulp. The irritant qualities seem to be
related to its ability to stimulate development of a calcified barrier. The superficial
necrotic area in the pulp that develops beneath the calcium hydroxide is demarcated from
the healthy pulp tissue below by a new, deeply staining zone comprised of basophilic
elements of the calcium hydroxide dressing.
The original proteinate zone is still present. However, against this zone is a
new area of coarse fibrous tissue likened to a primitive type of bone. On the periphery of
the new fibrous tissue, cells resembling odontoblasts appear to be lining up. One month
after the capping procedure, a calcified bridge is evident radiographically. This bridge
continues to increase in thickness during the next 12 months. The pulp tissue beneath the
calcified bridge remains vital and is essentially free of inflammatory cells.

PREPARATIONS CONTAINING FORMALIN


The clinical success experienced in the treatment of primary pulps with these
materials is due to the drug’s germicidal action and fixation qualities than to its ability to
promote healing.
Some studies have indicated that the formocresol pulpotomy technique may
be applied to permanent teeth, but its use in permanent teeth remains an interim
procedure, to be followed by conventional endodontic therapy.

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Lec.11 Pedodontics Fifth stage

Notes:
Recently, because of formocresol negative systemic properties, its use
should be limited. Formaldehyde has a known carcinogenic, immunogenic, toxic,
and mutagenic potential, which makes it questionable and unsuitable for use in
pedodontic endodontics.
Therefore, Biodentin and MTA can be used instead of it and other
experimental capping materials alternative to formocresol are:
 Laser Pulpotomy
 Electrosurgical Pulpotomy
 Bone morphogenic protein
 Calcium hydroxide Dentin chips

FERRIC SULFATE
Ferric sulfate (15.5% Fe2SO4) has been used as pulpotomy agent as a
substitute for formocresol for 15–20 years. Ferric sulfate in contact with blood forms a
ferric ion–protein complex, which seals the cut blood vessels mechanically, producing
hemostasis. The effect of ferric sulfate is hemostatic but not bactericidal or fixative. After
application of ferric sulfate for 15 seconds, the pulp is covered with zinc oxide–eugenol
and the cavity sealed.

Glutaraldehyde
It has been widely tested, to replace formocresol. Studies have shown that
application of 2-4% produces rapid surface fixation of the underlying pulp tissue.
Attributes of glutaraldehyde over formocresol
1) Forms strong intra- and intermolecular protein bonds leading to superior
fixation by cross linkage.
2) Diffusability is limited, thus reducing the apical extension of the material
3) Excellent antimicrobial property
4) Less dystrophic calcification
5) Produces initial zone of fixation that does not proceed apically
6) Readily excreted from the body. About 90% will be eliminated in 3 days.
7) 15-20 times less toxic than formocresol and have little potential for
chromosomal interference or mutagenecity.

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