Legacy of Tuskegee Syphilis Study
Legacy of Tuskegee Syphilis Study
It was called the "Tuskegee Study of Untreated Syphilis in the Negro Male".
"For 40 years, the U.S. Public Health Service has conducted a study in which human guinea pigs, not
given proper treatment, have died of syphilis and its side effects," AP reporter Jean Heller wrote on July
25, 1972, referring to one of America's most notorious medical experiments, the Tuskegee Syphilis Study.
Heller further noted, "The study was conducted to determine from autopsies what the disease does to the
human body."
The Public Health Service began the study in 1932 in conjunction with the Tuskegee Institute. Nearly 400
impoverished black men with syphilis from Macon County, Ala., were enrolled in the study. According to
the Centers for Disease Control, the men were told they were being treated for "bad blood," a local term
used to describe several illnesses, including syphilis, anemia and fatigue. For participating in the study,
the men were given free medical exams, free meals and free burial insurance.
They were never told they had syphilis, nor were they ever treated for it.
Taliford Clark of the Health Service defending why it was deemed appropriate to target poor and rural
Macon County, Alabama, stated "Macon County is a natural laboratory; a ready-made situation. The
rather low intelligence of the Negro population, depressed economic conditions, and the common
promiscuous sex relations not only contribute to the spread of syphilis but the prevailing indifference with
regard to treatment."
When several nationwide campaigns to eradicate venereal disease came to Macon County, the men were
prevented from participating. Moreover, when penicillin was discovered in the 1940s — the first real cure
for syphilis — the Tuskegee men were deliberately denied the medication. During World War II, 250 of
the men registered for the draft and were consequently ordered to get treatment for syphilis, only to have
the PHS exempt them. Pleased at their success, the PHS representative announced: “So far, we are
keeping the known positive patients from getting treatment.” The experiment continued in spite of both
the Henderson Act (1943), a public health law requiring testing and treatment for venereal disease, and
the World Health Organization's Declaration of Helsinki (1964), which specified that “informed consent”
was needed for any experiment involving human beings.
At the start of the study, there was no proven treatment for syphilis. But even after penicillin became a
standard cure for the disease in 1947, the medicine was withheld from the men. The Tuskegee scientists
wanted to continue to study how the disease spreads and kills. The experiment lasted four decades, until
public health workers eventually leaked the story to the media.
By then, dozens of the men had died, and many wives and children had been infected. In 1973, the
National Association for the Advancement of Colored People (NAACP) filed a class-action lawsuit. A $9
million settlement was divided among the study's participants, and free health care was given to the men
who were still living, and to their infected wives, widows and children.
It was not until 1997 that the government formally apologized for the study. President Clinton delivered
the apology, saying what the government had done was deeply, profoundly and morally wrong:
"To the survivors, to the wives and family members, the children and the grandchildren, I say what you
know: No power on Earth can give you back the lives lost, the pain suffered, the years of internal torment
and anguish.
"What was done cannot be undone. But we can end the silence. We can stop turning our heads away. We
can look at you in the eye and finally say, on behalf of the American people: what the United States
government did was shameful.
"And I am sorry."